| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bimatoprost perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bimatoprost_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.146359 |
| FAM107B | family with sequence similarity 107, member B | 0.0658858 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0639564 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0535753 |
| EHBP1 | EH domain binding protein 1 | 0.0535069 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0510213 |
| DSPP | dentin sialophosphoprotein | 0.045415 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0438258 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0407085 |
| FOXP1 | forkhead box P1 | 0.0404528 |
| ATXN1 | ataxin 1 | 0.0392355 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0339768 |
| GK | glycerol kinase | 0.0331286 |
| ASPH | aspartate beta-hydroxylase | 0.0330862 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0308246 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0305828 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0294084 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0290286 |
| ITGAV | integrin, alpha V | 0.0287687 |
| SMAD3 | SMAD family member 3 | 0.0269252 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0267005 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.026227 |
| SVIL | supervillin | 0.0255448 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0254891 |
| ZNF644 | zinc finger protein 644 | 0.0252859 |
| FAT1 | FAT atypical cadherin 1 | 0.0251386 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.025128 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0245714 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0245016 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0244948 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0243536 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0241918 |
| FRMD5 | FERM domain containing 5 | 0.0240682 |
| BCL2L1 | BCL2-like 1 | 0.0237911 |
| INTS6 | integrator complex subunit 6 | 0.0234255 |
| VCL | vinculin | 0.0234225 |
| MYO1E | myosin IE | 0.0226355 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0225752 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0224449 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0220391 |
| TPM1 | tropomyosin 1 (alpha) | 0.0220037 |
| DST | dystonin | 0.0218867 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0216322 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0212557 |
| DNAH5 | dynein, axonemal, heavy chain 5 | 0.0208051 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0208003 |
| RASA2 | RAS p21 protein activator 2 | 0.0207775 |
| DNAH17 | dynein, axonemal, heavy chain 17 | 0.0206441 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0205438 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0203453 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0201608 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0200236 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0199294 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0190812 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0182422 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0182363 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | 0.0180094 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0177459 |
| SERTAD2 | SERTA domain containing 2 | 0.0175857 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0175713 |
| SMYD3 | SET and MYND domain containing 3 | 0.0175046 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.017463 |
| RSU1 | Ras suppressor protein 1 | 0.017309 |
| GPC6 | glypican 6 | 0.017278 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0172706 |
| PRKCA | protein kinase C, alpha | 0.0170981 |
| RIGI | RNA sensor RIG-I | 0.0169523 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.016912 |
| FERMT1 | fermitin family member 1 | 0.0168577 |
| LMO7 | LIM domain 7 | 0.0167682 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0166488 |
| FMNL2 | formin-like 2 | 0.0165817 |
| RAD51B | RAD51 paralog B | 0.0162271 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0161729 |
| CADM1 | cell adhesion molecule 1 | 0.0159738 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0159059 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0157043 |
| CP | ceruloplasmin (ferroxidase) | 0.0156019 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0153233 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.015118 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0150353 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.015009 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0150089 |
| HPCAL1 | hippocalcin-like 1 | 0.0148039 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0146444 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0146159 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | 0.0146004 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0145261 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0143018 |
| DUSP16 | dual specificity phosphatase 16 | 0.0142871 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.014269 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.014212 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0141797 |
| FKBP5 | FK506 binding protein 5 | 0.0141613 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0141291 |
| KYNU | kynureninase | 0.0139533 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.013948 |
| AOPEP | aminopeptidase O (putative) | 0.0137917 |
| CANX | calnexin | 0.0136772 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0135343 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.316946 |
| IGF2 | insulin-like growth factor 2 | -0.179224 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.170019 |
| C3 | complement component 3 | -0.104984 |
| APOB | apolipoprotein B | -0.0617395 |
| MT2A | metallothionein 2A | -0.0608205 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0433291 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0428767 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0367778 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0358712 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0355369 |
| RPS6 | ribosomal protein S6 | -0.0346508 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0338533 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0332046 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0324697 |
| TMSB10 | thymosin beta 10 | -0.031245 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.0297968 |
| RPL23 | ribosomal protein L23 | -0.0272095 |
| FTL | ferritin, light polypeptide | -0.0262059 |
| VEGFA | vascular endothelial growth factor A | -0.0255444 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0251949 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0238803 |
| TMEM123 | transmembrane protein 123 | -0.0236721 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0233274 |
| FN1 | fibronectin 1 | -0.0230441 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0226478 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0223182 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0221557 |
| CPE | carboxypeptidase E | -0.0220954 |
| RPS19 | ribosomal protein S19 | -0.0219399 |
| H1-0 | H1.0 linker histone | -0.0219113 |
| ZNF292 | zinc finger protein 292 | -0.0218216 |
| A2M | alpha-2-macroglobulin | -0.0217855 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0217126 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0216986 |
| CFB | complement factor B | -0.0212099 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.020936 |
| HMGA1 | high mobility group AT-hook 1 | -0.0207634 |
| RPLP2 | ribosomal protein, large, P2 | -0.0204063 |
| APOA2 | apolipoprotein A-II | -0.0202572 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.0202466 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0202252 |
| PEG3 | paternally expressed 3 | -0.019445 |
| EGR1 | early growth response 1 | -0.0191338 |
| PKM | pyruvate kinase, muscle | -0.0186903 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0186685 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0185636 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -0.018543 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0181603 |
| RPLP1 | ribosomal protein, large, P1 | -0.0177269 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | -0.0176709 |
| DTNA | dystrobrevin, alpha | -0.0175696 |
| RBM25 | RNA binding motif protein 25 | -0.0175154 |
| CRLS1 | cardiolipin synthase 1 | -0.0174961 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0171736 |
| RPL35A | ribosomal protein L35a | -0.0169916 |
| PLIN2 | perilipin 2 | -0.0169672 |
| NDRG1 | N-myc downstream regulated 1 | -0.0163831 |
| LYZ | lysozyme | -0.0161208 |
| GSE1 | Gse1 coiled-coil protein | -0.0159372 |
| RPL26 | ribosomal protein L26 | -0.0159279 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0159199 |
| PFN1 | profilin 1 | -0.0158907 |
| RPL11 | ribosomal protein L11 | -0.0158519 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0158243 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.015682 |
| APOE | apolipoprotein E | -0.0155806 |
| RBM39 | RNA binding motif protein 39 | -0.0155724 |
| RPS12 | ribosomal protein S12 | -0.0154824 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0154595 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0152313 |
| TMEM51 | transmembrane protein 51 | -0.0152277 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0148032 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.0147061 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0146281 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0146201 |
| UBXN4 | UBX domain protein 4 | -0.014565 |
| CST3 | cystatin C | -0.0145247 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.014228 |
| PHYHIPL | phytanoyl-CoA 2-hydroxylase interacting protein-like | -0.0142173 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0141437 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.014097 |
| PCBP2 | poly(rC) binding protein 2 | -0.0139361 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0137662 |
| S100A9 | S100 calcium binding protein A9 | -0.0137061 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -0.0135998 |
| TLK1 | tousled-like kinase 1 | -0.013581 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0134158 |
| APOH | apolipoprotein H (beta-2-glycoprotein I) | -0.0134148 |
| RPS21 | ribosomal protein S21 | -0.0133902 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0133791 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0133234 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.013287 |
| RPL37A | ribosomal protein L37a | -0.0130075 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0127419 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | -0.0127286 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0127033 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.01266 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0125672 |
| RPS13 | ribosomal protein S13 | -0.0124274 |
