| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bimatoprost perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bimatoprost_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.0729214 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0681268 |
| MSN | moesin | 0.0603552 |
| INTS6 | integrator complex subunit 6 | 0.059611 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0564077 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0508771 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0504181 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0500732 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.048138 |
| HMGA2 | high mobility group AT-hook 2 | 0.0441576 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0440272 |
| CAPRIN2 | caprin family member 2 | 0.0436054 |
| EFNA5 | ephrin-A5 | 0.0393769 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0387569 |
| SEPTIN9 | septin 9 | 0.0370636 |
| FKBP5 | FK506 binding protein 5 | 0.034127 |
| PRELID2 | PRELI domain containing 2 | 0.0336975 |
| YAP1 | Yes-associated protein 1 | 0.0331919 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0329206 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0327013 |
| RPS12 | ribosomal protein S12 | 0.0324525 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0323673 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.031395 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0313156 |
| FAT1 | FAT atypical cadherin 1 | 0.0309602 |
| LUZP1 | leucine zipper protein 1 | 0.0297332 |
| SMAD3 | SMAD family member 3 | 0.0296366 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0292088 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.0289658 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0289361 |
| KRT6A | keratin 6A, type II | 0.0287595 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0279132 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0272073 |
| PLXNA2 | plexin A2 | 0.0268538 |
| CTBP2 | C-terminal binding protein 2 | 0.0262693 |
| MCL1 | myeloid cell leukemia 1 | 0.0257339 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0250031 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0249796 |
| RASAL2 | RAS protein activator like 2 | 0.0247166 |
| CLIC4 | chloride intracellular channel 4 | 0.0243767 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.02433 |
| SETX | senataxin | 0.0241394 |
| LMO7 | LIM domain 7 | 0.0239727 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0238995 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0233695 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0230071 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.022892 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0228816 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0227494 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0226375 |
| TJP1 | tight junction protein 1 | 0.022544 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0223589 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0222661 |
| GPR176 | G protein-coupled receptor 176 | 0.0221858 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0220206 |
| FNIP1 | folliculin interacting protein 1 | 0.0219365 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0217606 |
| FMNL2 | formin-like 2 | 0.0215072 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0214261 |
| LAMB1 | laminin, beta 1 | 0.021373 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0213313 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0212726 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0210759 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0209918 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0207245 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0204269 |
| TOP1 | topoisomerase (DNA) I | 0.0204172 |
| JAG1 | jagged 1 | 0.0195818 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0195679 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0193895 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0193232 |
| ARHGAP23 | Rho GTPase activating protein 23 | 0.0189243 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 | 0.0189149 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.018888 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0188709 |
| SLTM | SAFB-like, transcription modulator | 0.0186728 |
| TUT7 | terminal uridylyl transferase 7 | 0.0186632 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0185915 |
| IRS2 | insulin receptor substrate 2 | 0.0185025 |
| BLCAP | bladder cancer associated protein | 0.0184163 |
| ANO6 | anoctamin 6 | 0.0182512 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0182473 |
| LPAR1 | lysophosphatidic acid receptor 1 | 0.0181221 |
| JAK2 | Janus kinase 2 | 0.0180468 |
| TXNIP | thioredoxin interacting protein | 0.0178744 |
| KLF12 | Kruppel-like factor 12 | 0.0178687 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0178138 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.0178005 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0177134 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.017676 |
| FRMD6 | FERM domain containing 6 | 0.0172019 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0169209 |
| EHBP1 | EH domain binding protein 1 | 0.0169137 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0168963 |
| RASA2 | RAS p21 protein activator 2 | 0.0168796 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0168431 |
| VIM | vimentin | 0.0165378 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0165282 |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase | 0.0165212 |
| DGKH | diacylglycerol kinase, eta | 0.016507 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.243399 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.239249 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.213691 |
| NDRG1 | N-myc downstream regulated 1 | -0.159962 |
| SULF1 | sulfatase 1 | -0.112751 |
| MEF2A | myocyte enhancer factor 2A | -0.0981846 |
| MTSS1 | metastasis suppressor 1 | -0.0964849 |
| S100A10 | S100 calcium binding protein A10 | -0.0959753 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0948786 |
| RPS6 | ribosomal protein S6 | -0.090488 |
| STC1 | stanniocalcin 1 | -0.0882914 |
| GNAS | GNAS complex locus | -0.0790725 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0784695 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0768246 |
| HLA-B | major histocompatibility complex, class I, B | -0.0753499 |
| RPS8 | ribosomal protein S8 | -0.0715849 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0704915 |
| TMSB4X | thymosin beta 4, X-linked | -0.0698054 |
| IGF2 | insulin-like growth factor 2 | -0.0691325 |
| RAI14 | retinoic acid induced 14 | -0.0687425 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.068393 |
| RPLP1 | ribosomal protein, large, P1 | -0.0680102 |
| RPS21 | ribosomal protein S21 | -0.0678088 |
| LMNA | lamin A/C | -0.0677358 |
| FLNB | filamin B, beta | -0.0662642 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0658456 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0638963 |
| PGK1 | phosphoglycerate kinase 1 | -0.0638259 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0635402 |
| CLU | clusterin | -0.06287 |
| RPL8 | ribosomal protein L8 | -0.0612749 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0605228 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0597294 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.059304 |
| RPL35A | ribosomal protein L35a | -0.058953 |
| LDHA | lactate dehydrogenase A | -0.0588222 |
| ANXA2 | annexin A2 | -0.057893 |
| RPLP2 | ribosomal protein, large, P2 | -0.0576213 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0546272 |
| RPL34 | ribosomal protein L34 | -0.0516389 |
| RPS13 | ribosomal protein S13 | -0.0503942 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0491438 |
| ENO1 | enolase 1, (alpha) | -0.0482739 |
| EMP1 | epithelial membrane protein 1 | -0.0482169 |
| PKM | pyruvate kinase, muscle | -0.0481324 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0480467 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.047738 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0470752 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | -0.0458283 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0454394 |
| RRBP1 | ribosome binding protein 1 | -0.0449641 |
| MKI67 | marker of proliferation Ki-67 | -0.0446164 |
| GOLGA4 | golgin A4 | -0.0440065 |
| CALB1 | calbindin 1, 28kDa | -0.0437009 |
| SQLE | squalene epoxidase | -0.0425241 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0423822 |
| S100A2 | S100 calcium binding protein A2 | -0.0420544 |
| CSTB | cystatin B (stefin B) | -0.041642 |
| ACTN4 | actinin, alpha 4 | -0.041309 |
| AHNAK | AHNAK nucleoprotein | -0.0411488 |
| CD99 | CD99 molecule | -0.0409155 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.0402642 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0398389 |
| S100A11 | S100 calcium binding protein A11 | -0.0396746 |
| TMSB10 | thymosin beta 10 | -0.0393194 |
| S100A9 | S100 calcium binding protein A9 | -0.0386636 |
| YBX1 | Y box binding protein 1 | -0.0386293 |
| SQSTM1 | sequestosome 1 | -0.0385525 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0371008 |
| HLA-E | major histocompatibility complex, class I, E | -0.0358415 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0355296 |
| MT1X | metallothionein 1X | -0.0354614 |
| CAVIN1 | caveolae associated protein 1 | -0.0347764 |
| RPL11 | ribosomal protein L11 | -0.0347099 |
| KRT17 | keratin 17, type I | -0.0345867 |
| MT2A | metallothionein 2A | -0.0345825 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0344929 |
| RPL19 | ribosomal protein L19 | -0.0342506 |
| MYO10 | myosin X | -0.03419 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0339889 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0337204 |
| H1-0 | H1.0 linker histone | -0.0334679 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0333644 |
| S100A6 | S100 calcium binding protein A6 | -0.033217 |
| RPS27 | ribosomal protein S27 | -0.0330885 |
| EFHD2 | EF-hand domain family, member D2 | -0.0324639 |
| TPM4 | tropomyosin 4 | -0.0324623 |
| IER3 | immediate early response 3 | -0.032368 |
| HM13 | histocompatibility (minor) 13 | -0.0322092 |
| RPL28 | ribosomal protein L28 | -0.0321366 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0320458 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0319643 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0317402 |
| DOK5 | docking protein 5 | -0.0316738 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0313948 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.030772 |
| GUK1 | guanylate kinase 1 | -0.0307508 |
| RPL7A | ribosomal protein L7a | -0.0306798 |
| PODXL | podocalyxin-like | -0.0306788 |
| POTEF | POTE ankyrin domain family, member F | -0.0306293 |
