| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bimatoprost perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bimatoprost_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYO1E | myosin IE | 0.0555956 |
| RPS12 | ribosomal protein S12 | 0.0488329 |
| LMO7 | LIM domain 7 | 0.0402548 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0341986 |
| VCL | vinculin | 0.0277236 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0256965 |
| VIM | vimentin | 0.0254113 |
| ONECUT3 | one cut homeobox 3 | 0.0244455 |
| MT2A | metallothionein 2A | 0.0235588 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0227684 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0223571 |
| MUC13 | mucin 13, cell surface associated | 0.0222676 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0221107 |
| FN1 | fibronectin 1 | 0.0204985 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0204577 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0203964 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0198953 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0195725 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0191767 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0186729 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0185796 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0185303 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0178945 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0170221 |
| GPC6 | glypican 6 | 0.016965 |
| POF1B | premature ovarian failure, 1B | 0.0163317 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0162331 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0161746 |
| B2M | beta-2-microglobulin | 0.0160547 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0160257 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0151484 |
| DST | dystonin | 0.0146249 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.01444 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.014219 |
| PDE10A | phosphodiesterase 10A | 0.0139451 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0132185 |
| RIGI | RNA sensor RIG-I | 0.0131163 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.013091 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0130298 |
| TUFT1 | tuftelin 1 | 0.0125933 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0124089 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0122916 |
| RND3 | Rho family GTPase 3 | 0.0122656 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0122258 |
| RPL14 | ribosomal protein L14 | 0.0121091 |
| PLAUR | plasminogen activator, urokinase receptor | 0.011669 |
| CFAP44 | cilia and flagella associated protein 44 | 0.0113464 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0113134 |
| DUSP16 | dual specificity phosphatase 16 | 0.0113107 |
| WWOX | WW domain containing oxidoreductase | 0.0109032 |
| LAMB3 | laminin, beta 3 | 0.0108367 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.0108137 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0105781 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0104737 |
| SQSTM1 | sequestosome 1 | 0.0104283 |
| RPS7 | ribosomal protein S7 | 0.0102707 |
| AREG | amphiregulin | 0.0098982 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0098826 |
| PRKCSH | protein kinase C substrate 80K-H | 0.00981731 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.00978518 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.00968233 |
| SIDT1 | SID1 transmembrane family, member 1 | 0.00966448 |
| ANXA1 | annexin A1 | 0.00962836 |
| MYO6 | myosin VI | 0.00962738 |
| KIF5C | kinesin family member 5C | 0.00953754 |
| NAV2 | neuron navigator 2 | 0.00927673 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.00926253 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.00917793 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.00914959 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.00910567 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.00907239 |
| RDX | radixin | 0.00899126 |
| OSMR | oncostatin M receptor | 0.008961 |
| TMF1 | TATA element modulatory factor 1 | 0.00887634 |
| USP53 | ubiquitin specific peptidase 53 | 0.00877029 |
| TMC5 | transmembrane channel-like 5 | 0.00876967 |
| GLIS3 | GLIS family zinc finger 3 | 0.00875704 |
| RPS18 | ribosomal protein S18 | 0.00874319 |
| TNFSF15 | tumor necrosis factor (ligand) superfamily, member 15 | 0.00873095 |
| NABP1 | nucleic acid binding protein 1 | 0.00869738 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.00868279 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.00867914 |
| ATP5F1E | ATP synthase F1 subunit epsilon | 0.00860257 |
| NLGN1 | neuroligin 1 | 0.00858433 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.00850819 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | 0.00849208 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.00847945 |
| SMYD3 | SET and MYND domain containing 3 | 0.00839873 |
| TRIB1 | tribbles pseudokinase 1 | 0.00834554 |
| INTS6 | integrator complex subunit 6 | 0.00832141 |
| PRR5L | proline rich 5 like | 0.00824435 |
| COL6A3 | collagen, type VI, alpha 3 | 0.00823787 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.00823776 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.00821458 |
| MYOF | myoferlin | 0.00819984 |
| OFD1 | oral-facial-digital syndrome 1 | 0.00819716 |
| RAI14 | retinoic acid induced 14 | 0.00819205 |
| CRY1 | cryptochrome circadian clock 1 | 0.00816968 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.00813226 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0080877 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.346185 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.206623 |
| NPSR1 | neuropeptide S receptor 1 | -0.180374 |
| TMSB10 | thymosin beta 10 | -0.148024 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.111351 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.10875 |
| ITGA6 | integrin, alpha 6 | -0.0933705 |
| PTMA | prothymosin, alpha | -0.089519 |
| ANXA2 | annexin A2 | -0.087044 |
| PKM | pyruvate kinase, muscle | -0.0850952 |
| RPS6 | ribosomal protein S6 | -0.0843734 |
| ACTN4 | actinin, alpha 4 | -0.0679761 |
| KRT8 | keratin 8, type II | -0.0666241 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0659025 |
| TNS4 | tensin 4 | -0.0658222 |
| FLNB | filamin B, beta | -0.0657785 |
| LDHA | lactate dehydrogenase A | -0.0656937 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0637177 |
| POTEF | POTE ankyrin domain family, member F | -0.0622437 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0617224 |
| AHNAK | AHNAK nucleoprotein | -0.0614795 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0600555 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0590156 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0579134 |
| CALB1 | calbindin 1, 28kDa | -0.0561403 |
| TXNIP | thioredoxin interacting protein | -0.0555515 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0541936 |
| GPHN | gephyrin | -0.0536997 |
| S100A6 | S100 calcium binding protein A6 | -0.0521173 |
| PERP | PERP, TP53 apoptosis effector | -0.0509818 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0505692 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0498747 |
| UBC | ubiquitin C | -0.0495337 |
| RPL8 | ribosomal protein L8 | -0.0495089 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0482204 |
| RREB1 | ras responsive element binding protein 1 | -0.0459612 |
| KIF5B | kinesin family member 5B | -0.0454483 |
| ACTG1 | actin gamma 1 | -0.0452647 |
| KRT18 | keratin 18, type I | -0.0451069 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0449246 |
| EPCAM | epithelial cell adhesion molecule | -0.0442814 |
| GOLGA4 | golgin A4 | -0.0435776 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0428234 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0424801 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.042413 |
| HMGA1 | high mobility group AT-hook 1 | -0.0423333 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0422895 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0417645 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0414909 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0408661 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0403424 |
| MUC17 | mucin 17, cell surface associated | -0.0401402 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.0396198 |
| PTEN | phosphatase and tensin homolog | -0.0393408 |
| LMNA | lamin A/C | -0.0391161 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0383536 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0382216 |
| SETD5 | SET domain containing 5 | -0.0371779 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0368203 |
| PIGR | polymeric immunoglobulin receptor | -0.0367596 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0363591 |
| RPS23 | ribosomal protein S23 | -0.0363142 |
| NFIA | nuclear factor I/A | -0.0361963 |
| RPL23 | ribosomal protein L23 | -0.0352175 |
| ENO1 | enolase 1, (alpha) | -0.0348168 |
| FERMT1 | fermitin family member 1 | -0.0343652 |
| YBX1 | Y box binding protein 1 | -0.0341655 |
| ITGB4 | integrin, beta 4 | -0.0341492 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0340835 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0340317 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0339256 |
| DEK | DEK proto-oncogene | -0.0331427 |
| TPM4 | tropomyosin 4 | -0.032883 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0328369 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0325838 |
| CCND1 | cyclin D1 | -0.0325587 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0322537 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0321863 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0320933 |
| PRSS3 | protease, serine, 3 | -0.0318362 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | -0.0313168 |
| FOSL1 | FOS-like antigen 1 | -0.0311111 |
| FAM13A | family with sequence similarity 13, member A | -0.0310782 |
| RPS5 | ribosomal protein S5 | -0.0310738 |
| RPL32 | ribosomal protein L32 | -0.0310477 |
| RNF43 | ring finger protein 43 | -0.0309963 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0305629 |
| SBF2 | SET binding factor 2 | -0.0303309 |
| S100A10 | S100 calcium binding protein A10 | -0.0303058 |
| RPL35A | ribosomal protein L35a | -0.0302353 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0299912 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0298335 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0298245 |
| PFN1 | profilin 1 | -0.029818 |
| PCBP2 | poly(rC) binding protein 2 | -0.0297897 |
| RPS8 | ribosomal protein S8 | -0.0297523 |
| TRIM2 | tripartite motif containing 2 | -0.0293756 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0293324 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0292936 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0289771 |
