| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bimatoprost perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bimatoprost_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CAPRIN2 | caprin family member 2 | 0.0750126 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0735202 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0663752 |
| MT2A | metallothionein 2A | 0.060532 |
| RPS12 | ribosomal protein S12 | 0.0601535 |
| ENO1 | enolase 1, (alpha) | 0.058726 |
| PRELID2 | PRELI domain containing 2 | 0.0571852 |
| ANGPTL4 | angiopoietin-like 4 | 0.0563843 |
| DST | dystonin | 0.0518949 |
| PDE10A | phosphodiesterase 10A | 0.0503857 |
| CADM2 | cell adhesion molecule 2 | 0.0499893 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0471541 |
| SLK | STE20-like kinase | 0.0426451 |
| TMSB4X | thymosin beta 4, X-linked | 0.0422845 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0418306 |
| B2M | beta-2-microglobulin | 0.0415035 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0406336 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0403802 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0383217 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0366272 |
| RPL37A | ribosomal protein L37a | 0.0347988 |
| MSN | moesin | 0.0324943 |
| ASPH | aspartate beta-hydroxylase | 0.0319004 |
| VCL | vinculin | 0.0310695 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0310495 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.030772 |
| RPL37 | ribosomal protein L37 | 0.0307191 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.030608 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0297718 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0296654 |
| RPS27A | ribosomal protein S27a | 0.028089 |
| PYGL | phosphorylase, glycogen, liver | 0.0274303 |
| HLA-B | major histocompatibility complex, class I, B | 0.0267016 |
| RTTN | rotatin | 0.0260963 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.026022 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0255721 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0254131 |
| SET | SET nuclear proto-oncogene | 0.0253913 |
| PRKCE | protein kinase C, epsilon | 0.0253186 |
| F2R | coagulation factor II (thrombin) receptor | 0.0247624 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0245767 |
| RPL26 | ribosomal protein L26 | 0.024001 |
| CUX1 | cut-like homeobox 1 | 0.0231897 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0230502 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0229368 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0229188 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0228803 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0223786 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0221593 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0218806 |
| TPRG1 | tumor protein p63 regulated 1 | 0.0217991 |
| RPS6 | ribosomal protein S6 | 0.0213277 |
| RPS18 | ribosomal protein S18 | 0.0209792 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0206869 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.020624 |
| DNER | delta/notch-like EGF repeat containing | 0.0204659 |
| AREG | amphiregulin | 0.0201416 |
| PTMA | prothymosin, alpha | 0.0200223 |
| TPM3 | tropomyosin 3 | 0.0198903 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0198372 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0198257 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0197354 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0196697 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0195005 |
| RPL36A | ribosomal protein L36a | 0.0194207 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0194095 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0192356 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0191816 |
| VMP1 | vacuole membrane protein 1 | 0.0189523 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0189147 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0186831 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0185879 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0185876 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0183144 |
| TSC22D1 | TSC22 domain family, member 1 | 0.018292 |
| DSTN | destrin (actin depolymerizing factor) | 0.0182737 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0181083 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0175814 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0171102 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0170953 |
| CEP290 | centrosomal protein 290kDa | 0.0170386 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0170072 |
| RBM25 | RNA binding motif protein 25 | 0.0169058 |
| GRAMD1B | GRAM domain containing 1B | 0.0168845 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0167382 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0167092 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0165235 |
| RPL27 | ribosomal protein L27 | 0.0164396 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0164256 |
| MYO9A | myosin IXA | 0.0163441 |
| NDRG1 | N-myc downstream regulated 1 | 0.0162921 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0161472 |
| RPS17 | ribosomal protein S17 | 0.016068 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0159967 |
| SMYD3 | SET and MYND domain containing 3 | 0.0159961 |
| RAD51B | RAD51 paralog B | 0.0159765 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0157741 |
| FMNL2 | formin-like 2 | 0.0155608 |
| RPS3 | ribosomal protein S3 | 0.0152028 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0151589 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.477853 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.121191 |
| TXNRD1 | thioredoxin reductase 1 | -0.113445 |
| VIM | vimentin | -0.107671 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0987944 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0972343 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0918987 |
| TMSB10 | thymosin beta 10 | -0.0855622 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0834083 |
| CD44 | CD44 molecule (Indian blood group) | -0.0818212 |
| AHNAK | AHNAK nucleoprotein | -0.0810088 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0771797 |
| ACTG1 | actin gamma 1 | -0.0742654 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0647059 |
| POTEF | POTE ankyrin domain family, member F | -0.0620579 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0587993 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0571972 |
| EGR1 | early growth response 1 | -0.0555108 |
| HDLBP | high density lipoprotein binding protein | -0.0535487 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0516989 |
| FTL | ferritin, light polypeptide | -0.0498198 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0431874 |
| USP34 | ubiquitin specific peptidase 34 | -0.042269 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.042205 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0418338 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0414186 |
| TMEM123 | transmembrane protein 123 | -0.0398868 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0381999 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0372925 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0368059 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0366115 |
| RGS4 | regulator of G-protein signaling 4 | -0.0343057 |
| APP | amyloid beta (A4) precursor protein | -0.0339832 |
| SPAG9 | sperm associated antigen 9 | -0.0338016 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0331786 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0331492 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0330064 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0327749 |
| EHBP1 | EH domain binding protein 1 | -0.0325069 |
| TOP1 | topoisomerase (DNA) I | -0.0325036 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0324685 |
| RAI1 | retinoic acid induced 1 | -0.0321616 |
| MKI67 | marker of proliferation Ki-67 | -0.0320022 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0319585 |
| GSK3B | glycogen synthase kinase 3 beta | -0.031717 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0315381 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0304686 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0298425 |
| CANX | calnexin | -0.0297626 |
| ANKRD28 | ankyrin repeat domain 28 | -0.029309 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0289214 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0287532 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0282608 |
| ZNF217 | zinc finger protein 217 | -0.0281766 |
| LOXL2 | lysyl oxidase-like 2 | -0.0280085 |
| HPCAL1 | hippocalcin-like 1 | -0.0278779 |
| FBXO11 | F-box protein 11 | -0.027611 |
| CMIP | c-Maf inducing protein | -0.0275987 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0273017 |
| RUNX1 | runt-related transcription factor 1 | -0.0271866 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0267858 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0266156 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0262194 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0261752 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0259976 |
| TAOK1 | TAO kinase 1 | -0.0257783 |
| YBX1 | Y box binding protein 1 | -0.0256674 |
| SRGN | serglycin | -0.0256504 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.025575 |
| EPHA4 | EPH receptor A4 | -0.0252227 |
| RASAL2 | RAS protein activator like 2 | -0.025124 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0249715 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -0.0249451 |
| RPL8 | ribosomal protein L8 | -0.0244759 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0243863 |
| LDHA | lactate dehydrogenase A | -0.0242321 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0231103 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0228468 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0224808 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0223038 |
| FLNB | filamin B, beta | -0.0218776 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0216855 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0216405 |
| NAV2 | neuron navigator 2 | -0.0213359 |
| ANKRD50 | ankyrin repeat domain 50 | -0.0213265 |
| SBF2 | SET binding factor 2 | -0.02131 |
| CENPF | centromere protein F, 350/400kDa | -0.0212179 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0211787 |
| ECT2 | epithelial cell transforming 2 | -0.0211732 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0208291 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0206628 |
| AFAP1 | actin filament associated protein 1 | -0.0206426 |
| RPS8 | ribosomal protein S8 | -0.0204591 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0204557 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0204418 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0203997 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0202872 |
| ANLN | anillin, actin binding protein | -0.0201429 |
| STK17A | serine/threonine kinase 17a | -0.0201151 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0199757 |
