| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bimatoprost perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bimatoprost_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.267134 |
| HMGA2 | high mobility group AT-hook 2 | 0.0961659 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0839001 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0813777 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0648119 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0604123 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.05806 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0557789 |
| FAM20C | family with sequence similarity 20, member C | 0.0552396 |
| LOX | lysyl oxidase | 0.0507077 |
| SMAD3 | SMAD family member 3 | 0.0494768 |
| FN1 | fibronectin 1 | 0.0494712 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0491187 |
| PRELID2 | PRELI domain containing 2 | 0.0476865 |
| ASPH | aspartate beta-hydroxylase | 0.0453881 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0449421 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0425152 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0411079 |
| FKBP5 | FK506 binding protein 5 | 0.0410393 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0408015 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0383317 |
| INTS6 | integrator complex subunit 6 | 0.0360364 |
| NAV2 | neuron navigator 2 | 0.0353924 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0337579 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0333132 |
| NEBL | nebulette | 0.0329265 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0321358 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0314803 |
| ZNF638 | zinc finger protein 638 | 0.0313542 |
| AADAC | arylacetamide deacetylase | 0.0306761 |
| EFNA5 | ephrin-A5 | 0.0303966 |
| NTN4 | netrin 4 | 0.0303846 |
| TGM2 | transglutaminase 2 | 0.0291873 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0291425 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0286385 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0282426 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0279928 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.027137 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.0269188 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0267927 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0258295 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0254181 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0253208 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0253049 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.0243977 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0242676 |
| MYO10 | myosin X | 0.0238748 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0237754 |
| NRCAM | neuronal cell adhesion molecule | 0.0230601 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0227555 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0227341 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0226346 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0225824 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0224472 |
| AHNAK | AHNAK nucleoprotein | 0.0224146 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.022385 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0216387 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0213827 |
| CAPRIN2 | caprin family member 2 | 0.0213571 |
| RAD51B | RAD51 paralog B | 0.02106 |
| SMYD3 | SET and MYND domain containing 3 | 0.0210462 |
| ZMYND11 | zinc finger, MYND-type containing 11 | 0.0210042 |
| UTRN | utrophin | 0.0208664 |
| RNF144A | ring finger protein 144A | 0.0207295 |
| RHCG | Rh family, C glycoprotein | 0.0206224 |
| APP | amyloid beta (A4) precursor protein | 0.0204111 |
| MT2A | metallothionein 2A | 0.0194257 |
| TUT7 | terminal uridylyl transferase 7 | 0.0193401 |
| ZBTB16 | zinc finger and BTB domain containing 16 | 0.0184802 |
| ATXN1 | ataxin 1 | 0.0184543 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0184471 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0182665 |
| KSR1 | kinase suppressor of ras 1 | 0.0181312 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0181225 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0180773 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0178767 |
| LOXL2 | lysyl oxidase-like 2 | 0.0176082 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0175579 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0175028 |
| CPNE1 | copine I | 0.0174802 |
| IL1R1 | interleukin 1 receptor, type I | 0.0174749 |
| ANO6 | anoctamin 6 | 0.0173703 |
| HDAC4 | histone deacetylase 4 | 0.0171555 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0170742 |
| MYOF | myoferlin | 0.0170126 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0168658 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.0166236 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.016601 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0163826 |
| DST | dystonin | 0.0161643 |
| NABP1 | nucleic acid binding protein 1 | 0.0161352 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0160808 |
| ANGPTL4 | angiopoietin-like 4 | 0.0160354 |
| ITGA10 | integrin, alpha 10 | 0.0160136 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0159247 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0158538 |
| MLPH | melanophilin | 0.0158417 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0155819 |
| WWOX | WW domain containing oxidoreductase | 0.0154995 |
| STK38L | serine/threonine kinase 38 like | 0.0152798 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.203428 |
| VIM | vimentin | -0.163012 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.157828 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.140646 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0963453 |
| FTL | ferritin, light polypeptide | -0.0891461 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0870858 |
| STC1 | stanniocalcin 1 | -0.0813741 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0790606 |
| S100A6 | S100 calcium binding protein A6 | -0.0731851 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0677151 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0665617 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0657808 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0645059 |
| OSMR | oncostatin M receptor | -0.062591 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0620762 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0613011 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0611696 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0601454 |
| MEF2A | myocyte enhancer factor 2A | -0.0566884 |
| GOLGA4 | golgin A4 | -0.055173 |
| PTMA | prothymosin, alpha | -0.0544358 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0538941 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0533924 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0511329 |
| GLCCI1 | glucocorticoid induced 1 | -0.0497239 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0490193 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.048477 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.048148 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0478887 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0476283 |
| B2M | beta-2-microglobulin | -0.0458126 |
| TMEM165 | transmembrane protein 165 | -0.0456133 |
| RPS19 | ribosomal protein S19 | -0.0437267 |
| CDCP1 | CUB domain containing protein 1 | -0.0436369 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0425689 |
| EGR1 | early growth response 1 | -0.0425499 |
| HMGA1 | high mobility group AT-hook 1 | -0.042259 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0409786 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0407935 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0405931 |
| FNDC3B | fibronectin type III domain containing 3B | -0.039815 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0381438 |
| SNX9 | sorting nexin 9 | -0.0379922 |
| FNBP1 | formin binding protein 1 | -0.0374912 |
| RPL35A | ribosomal protein L35a | -0.0372467 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0370942 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0362418 |
| ETV6 | ets variant 6 | -0.0359269 |
| SETD5 | SET domain containing 5 | -0.0358436 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0357256 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0352741 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0348992 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0347707 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0345479 |
| NRP1 | neuropilin 1 | -0.0340724 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0339093 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.033897 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0338742 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0338545 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0336513 |
| NDRG1 | N-myc downstream regulated 1 | -0.0336453 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0335886 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0332886 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0332249 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0329408 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0328403 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0321689 |
| DENND4A | DENN/MADD domain containing 4A | -0.0319817 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0318688 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0318278 |
| RPS6 | ribosomal protein S6 | -0.0317546 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0315736 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0315311 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0313894 |
| RPS21 | ribosomal protein S21 | -0.0313269 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0312713 |
| POTEF | POTE ankyrin domain family, member F | -0.0306755 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0302095 |
| PKM | pyruvate kinase, muscle | -0.0299715 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.029955 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0299444 |
| VRK2 | vaccinia related kinase 2 | -0.0296228 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0295153 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0293352 |
| USP34 | ubiquitin specific peptidase 34 | -0.0292714 |
| RPL36 | ribosomal protein L36 | -0.0292497 |
| RPLP1 | ribosomal protein, large, P1 | -0.0289692 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.0287653 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0286961 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0278239 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0276062 |
| RPS13 | ribosomal protein S13 | -0.0275495 |
| MAP1B | microtubule-associated protein 1B | -0.0272774 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0272689 |
| RNF24 | ring finger protein 24 | -0.0272665 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0269923 |
| RPL37A | ribosomal protein L37a | -0.0268645 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0267299 |
| MTSS1 | metastasis suppressor 1 | -0.0264249 |
