| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bimatoprost perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bimatoprost_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.161451 |
| EGFR | epidermal growth factor receptor | 0.160512 |
| GRAMD1B | GRAM domain containing 1B | 0.096989 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.087722 |
| GOLGA4 | golgin A4 | 0.0829687 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0769214 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0687516 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0682843 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0682233 |
| KYNU | kynureninase | 0.0672848 |
| TENM3 | teneurin transmembrane protein 3 | 0.0644424 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0644361 |
| HMGA2 | high mobility group AT-hook 2 | 0.0636298 |
| SMAD3 | SMAD family member 3 | 0.0634096 |
| PTK2 | protein tyrosine kinase 2 | 0.0619979 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.059866 |
| TJP1 | tight junction protein 1 | 0.0576837 |
| ASPH | aspartate beta-hydroxylase | 0.0568782 |
| CTBP2 | C-terminal binding protein 2 | 0.0551137 |
| CLTC | clathrin, heavy chain (Hc) | 0.055033 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0548638 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.054648 |
| MYO1E | myosin IE | 0.0536355 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0536046 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0502559 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0495495 |
| ITGA6 | integrin, alpha 6 | 0.0492671 |
| MYO10 | myosin X | 0.0491677 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0488792 |
| INTS6 | integrator complex subunit 6 | 0.0487092 |
| PRELID2 | PRELI domain containing 2 | 0.0485818 |
| AREG | amphiregulin | 0.0484184 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0476572 |
| CADM1 | cell adhesion molecule 1 | 0.047619 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0474546 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0470418 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0468763 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0467766 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0460317 |
| MED13L | mediator complex subunit 13-like | 0.0459616 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0458771 |
| MED13 | mediator complex subunit 13 | 0.0456956 |
| FAT1 | FAT atypical cadherin 1 | 0.0450286 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0450227 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0441568 |
| MT2A | metallothionein 2A | 0.043937 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0435848 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0432742 |
| INHBA | inhibin, beta A | 0.0424499 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0419815 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0413911 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0408084 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0406875 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0401213 |
| RPS4X | ribosomal protein S4, X-linked | 0.0400359 |
| YTHDC1 | YTH domain containing 1 | 0.0397818 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0396001 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0385097 |
| TMSB4X | thymosin beta 4, X-linked | 0.0384741 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0383082 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0380055 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.037916 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0375092 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0369831 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.036874 |
| GPHN | gephyrin | 0.0356274 |
| TPR | translocated promoter region, nuclear basket protein | 0.0353113 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0351749 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0351301 |
| TMF1 | TATA element modulatory factor 1 | 0.0348546 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0340624 |
| FNDC3B | fibronectin type III domain containing 3B | 0.034016 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0337079 |
| MAP7 | microtubule-associated protein 7 | 0.0336065 |
| UBR1 | ubiquitin protein ligase E3 component n-recognin 1 | 0.0335059 |
| TRIM2 | tripartite motif containing 2 | 0.0334715 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0331258 |
| ZNF644 | zinc finger protein 644 | 0.0330204 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.032856 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0328037 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0322178 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0321425 |
| MATR3 | matrin 3 | 0.0319823 |
| EFNA5 | ephrin-A5 | 0.0312845 |
| FHIT | fragile histidine triad | 0.0310771 |
| RPS12 | ribosomal protein S12 | 0.0310704 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 | 0.0310521 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0308498 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0305432 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.0304751 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0304069 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0302286 |
| PDE8A | phosphodiesterase 8A | 0.0297731 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.0294855 |
| VCL | vinculin | 0.0294013 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0290186 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0288883 |
| MYOF | myoferlin | 0.0288627 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0287715 |
| DENND5A | DENN/MADD domain containing 5A | 0.0287539 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ATOSA | atos homolog A | -0.15864 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.122213 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.117918 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.112573 |
| IGF2 | insulin-like growth factor 2 | -0.112211 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.109402 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.107261 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0851276 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0849767 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0772143 |
| S100A9 | S100 calcium binding protein A9 | -0.0722848 |
| FN1 | fibronectin 1 | -0.0693152 |
| FTL | ferritin, light polypeptide | -0.0691481 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0686471 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0681107 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0676197 |
| MXD1 | MAX dimerization protein 1 | -0.0667378 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0628306 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0620178 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0566531 |
| STC1 | stanniocalcin 1 | -0.0541638 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0533201 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0520819 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0520349 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0517407 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0506535 |
| SBF2 | SET binding factor 2 | -0.0505655 |
| B2M | beta-2-microglobulin | -0.0504175 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0488964 |
| FOXO3 | forkhead box O3 | -0.0482739 |
| SVIL | supervillin | -0.048234 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0475587 |
| TAOK3 | TAO kinase 3 | -0.0474342 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0465218 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.0460665 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0459968 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0455867 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0451862 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0437202 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0431205 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0417773 |
| RPL23 | ribosomal protein L23 | -0.0416013 |
| HLA-B | major histocompatibility complex, class I, B | -0.0413228 |
| RREB1 | ras responsive element binding protein 1 | -0.0411007 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0410515 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0410385 |
| ANXA2 | annexin A2 | -0.0393138 |
| ATP11B | ATPase, class VI, type 11B | -0.0391241 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0391149 |
| FAM107B | family with sequence similarity 107, member B | -0.0388379 |
| LAMB3 | laminin, beta 3 | -0.0387626 |
| WDR26 | WD repeat domain 26 | -0.0385462 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0385142 |
| HELZ | helicase with zinc finger | -0.0383713 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0382139 |
| GPC6 | glypican 6 | -0.0377747 |
| TXNRD1 | thioredoxin reductase 1 | -0.0374198 |
| H3-3B | H3.3 histone B | -0.0373656 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0372474 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | -0.037083 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0370108 |
| UBXN4 | UBX domain protein 4 | -0.0369591 |
| CSTB | cystatin B (stefin B) | -0.0366132 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0365161 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | -0.0364315 |
| ZNF207 | zinc finger protein 207 | -0.0363652 |
| FMN1 | formin 1 | -0.0363132 |
| S100A8 | S100 calcium binding protein A8 | -0.036073 |
| TMEM123 | transmembrane protein 123 | -0.0360657 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0358575 |
| RPL31 | ribosomal protein L31 | -0.0356456 |
| WASF2 | WAS protein family, member 2 | -0.0353152 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0351293 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0350599 |
| BBX | bobby sox homolog (Drosophila) | -0.0350124 |
| FDPS | farnesyl diphosphate synthase | -0.0344724 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0343963 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0340779 |
| RIOK3 | RIO kinase 3 | -0.0338193 |
| KLF6 | Kruppel-like factor 6 | -0.0337254 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0334409 |
| HLA-A | major histocompatibility complex, class I, A | -0.0334103 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0332846 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0330615 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0328428 |
| SRPK2 | SRSF protein kinase 2 | -0.0327597 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0324848 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | -0.0318053 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0316514 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0315996 |
| CLDN4 | claudin 4 | -0.0315009 |
| AGFG1 | ArfGAP with FG repeats 1 | -0.0314823 |
| RUNX1 | runt-related transcription factor 1 | -0.0312105 |
| ABHD17C | abhydrolase domain containing 17C | -0.0311466 |
| PLAU | plasminogen activator, urokinase | -0.0308128 |
| UBAP1 | ubiquitin associated protein 1 | -0.0306594 |
| VIM | vimentin | -0.0301785 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0301501 |
| S100P | S100 calcium binding protein P | -0.0300552 |
| ZNF217 | zinc finger protein 217 | -0.0299221 |
