| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bimatoprost perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bimatoprost_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.180324 |
| MCL1 | myeloid cell leukemia 1 | 0.124135 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0932884 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0782443 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0606188 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0589762 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0580153 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0553932 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0532465 |
| INTS6 | integrator complex subunit 6 | 0.0526322 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0523542 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0495571 |
| HOMER1 | homer scaffolding protein 1 | 0.0476378 |
| DST | dystonin | 0.0474002 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0452274 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0448417 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0423016 |
| AEBP2 | AE binding protein 2 | 0.0400709 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0398347 |
| YBX3 | Y box binding protein 3 | 0.0395934 |
| VCL | vinculin | 0.0374493 |
| MSN | moesin | 0.0366739 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0365738 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0345574 |
| PRELID2 | PRELI domain containing 2 | 0.0345124 |
| YAP1 | Yes-associated protein 1 | 0.0339711 |
| DSPP | dentin sialophosphoprotein | 0.0320722 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.0315209 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0312278 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0306783 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0304711 |
| SET | SET nuclear proto-oncogene | 0.0301479 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0297122 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0297077 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0295925 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.029211 |
| POTEF | POTE ankyrin domain family, member F | 0.0289186 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0284401 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0278244 |
| FERMT2 | fermitin family member 2 | 0.0275215 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0263493 |
| CALD1 | caldesmon 1 | 0.0262746 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0258024 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0256882 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0256794 |
| GDI2 | GDP dissociation inhibitor 2 | 0.0256045 |
| CPNE1 | copine I | 0.0254956 |
| ASPH | aspartate beta-hydroxylase | 0.0253948 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0253437 |
| ATXN1 | ataxin 1 | 0.024941 |
| WWOX | WW domain containing oxidoreductase | 0.0249301 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0245752 |
| NEK10 | NIMA-related kinase 10 | 0.0244163 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0241072 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0239488 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0238989 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0236414 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0234541 |
| CALR | calreticulin | 0.0233264 |
| TPM3 | tropomyosin 3 | 0.0232391 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0229858 |
| GRAMD1B | GRAM domain containing 1B | 0.0225003 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0216918 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.02163 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0213498 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0213078 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0212974 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0212764 |
| TRIM59 | tripartite motif containing 59 | 0.0212352 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0210046 |
| RRM2 | ribonucleotide reductase M2 | 0.0209764 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0209281 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0208726 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0208637 |
| BRD2 | bromodomain containing 2 | 0.0206018 |
| DOCK5 | dedicator of cytokinesis 5 | 0.020588 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0203392 |
| RCOR1 | REST corepressor 1 | 0.0202945 |
| CERS2 | ceramide synthase 2 | 0.0202091 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0201595 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.0200971 |
| KRT18 | keratin 18, type I | 0.0198005 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | 0.0196124 |
| CANX | calnexin | 0.0195741 |
| B2M | beta-2-microglobulin | 0.0195305 |
| CUX1 | cut-like homeobox 1 | 0.0195288 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0194882 |
| SETX | senataxin | 0.0194723 |
| FNIP1 | folliculin interacting protein 1 | 0.0193014 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0190558 |
| R3HDM2 | R3H domain containing 2 | 0.01885 |
| STYK1 | serine/threonine/tyrosine kinase 1 | 0.0187957 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0185792 |
| DUSP16 | dual specificity phosphatase 16 | 0.0185157 |
| RPL3 | ribosomal protein L3 | 0.0184894 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0184566 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 0.0181411 |
| MACROD2 | MACRO domain containing 2 | 0.0179122 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0178646 |
| CEP128 | centrosomal protein 128kDa | 0.0173965 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.23062 |
| TXNRD1 | thioredoxin reductase 1 | -0.106093 |
| TMSB10 | thymosin beta 10 | -0.09724 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0749278 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0745327 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0737028 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0711336 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0567321 |
| ZFR | zinc finger RNA binding protein | -0.0555254 |
| RTN4 | reticulon 4 | -0.0535842 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0513878 |
| RPL35A | ribosomal protein L35a | -0.0482857 |
| XPO1 | exportin 1 | -0.0481682 |
| RSF1 | remodeling and spacing factor 1 | -0.0478501 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0463279 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0460635 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.04595 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0457877 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0453195 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0452038 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0447239 |
| CAVIN1 | caveolae associated protein 1 | -0.0439563 |
| ZNF292 | zinc finger protein 292 | -0.0438066 |
| TLK1 | tousled-like kinase 1 | -0.0429504 |
| OSMR | oncostatin M receptor | -0.0427299 |
| TMEM165 | transmembrane protein 165 | -0.0421091 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0414623 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0410143 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0409808 |
| IGF2 | insulin-like growth factor 2 | -0.0409731 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0409713 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0408984 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0404905 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0403859 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0398755 |
| BBX | bobby sox homolog (Drosophila) | -0.0396712 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0396223 |
| GNAS | GNAS complex locus | -0.0391626 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.0389757 |
| IGF2BP1 | insulin-like growth factor 2 mRNA binding protein 1 | -0.038813 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0388106 |
| EPN2 | epsin 2 | -0.038275 |
| EGR1 | early growth response 1 | -0.0376806 |
| PHF21A | PHD finger protein 21A | -0.0375356 |
| SEPTIN7 | septin 7 | -0.0373888 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0371536 |
| RPL37 | ribosomal protein L37 | -0.0369895 |
| CCND2 | cyclin D2 | -0.0369478 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0364896 |
| PHIP | pleckstrin homology domain interacting protein | -0.0362894 |
| NF1 | neurofibromin 1 | -0.035756 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0356522 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0354471 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0351239 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0349073 |
| GATAD2B | GATA zinc finger domain containing 2B | -0.0348438 |
| RAD51B | RAD51 paralog B | -0.0343226 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0342886 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0337414 |
| LATS2 | large tumor suppressor kinase 2 | -0.0335607 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0335396 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | -0.033448 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0333908 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0331928 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0331319 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0327332 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0325841 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0319767 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0318828 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0318176 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.031762 |
| CCDC91 | coiled-coil domain containing 91 | -0.0317262 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0317204 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0313405 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0313275 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0312344 |
| RPLP1 | ribosomal protein, large, P1 | -0.0312237 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0311576 |
| TNPO3 | transportin 3 | -0.0310948 |
| NEMF | nuclear export mediator factor | -0.0309322 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.0308623 |
| RPL34 | ribosomal protein L34 | -0.0305833 |
| RPS8 | ribosomal protein S8 | -0.0303845 |
| RPL26 | ribosomal protein L26 | -0.0302566 |
| RPS21 | ribosomal protein S21 | -0.0302146 |
| RBM39 | RNA binding motif protein 39 | -0.0301167 |
| HMGA1 | high mobility group AT-hook 1 | -0.0300877 |
| RPL12 | ribosomal protein L12 | -0.0299379 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0296266 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0289853 |
| RNF169 | ring finger protein 169 | -0.0288218 |
| R3HDM1 | R3H domain containing 1 | -0.0288211 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0286445 |
| LDHB | lactate dehydrogenase B | -0.0284012 |
| H1-0 | H1.0 linker histone | -0.0281549 |
| ATXN2 | ataxin 2 | -0.0280875 |
| IMMT | inner membrane protein, mitochondrial | -0.0279862 |
| FTL | ferritin, light polypeptide | -0.027985 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0278246 |
| NUP153 | nucleoporin 153kDa | -0.0277084 |
