| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bimatoprost perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bimatoprost_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.125807 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0970107 |
| LAMB3 | laminin, beta 3 | 0.0825801 |
| RPS12 | ribosomal protein S12 | 0.0821751 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0768663 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.073238 |
| HMGB2 | high mobility group box 2 | 0.069136 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0672393 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0633242 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0618854 |
| MT2A | metallothionein 2A | 0.0582268 |
| MSN | moesin | 0.0566227 |
| RPS3 | ribosomal protein S3 | 0.0563302 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0500351 |
| DSPP | dentin sialophosphoprotein | 0.0456603 |
| RPL9 | ribosomal protein L9 | 0.0440907 |
| RPLP0 | ribosomal protein, large, P0 | 0.0438224 |
| RPL7 | ribosomal protein L7 | 0.0435045 |
| SDC4 | syndecan 4 | 0.0410117 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0399948 |
| CANX | calnexin | 0.0386759 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0384919 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.037948 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0375222 |
| RPL37A | ribosomal protein L37a | 0.0361924 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0359368 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0350984 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0350802 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0346763 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0344491 |
| ENO1 | enolase 1, (alpha) | 0.0343703 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0339203 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0337862 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.033698 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0333209 |
| LAMC2 | laminin, gamma 2 | 0.0323411 |
| RPL37 | ribosomal protein L37 | 0.032189 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0307423 |
| ANXA1 | annexin A1 | 0.0306747 |
| SGMS2 | sphingomyelin synthase 2 | 0.0306412 |
| NDRG1 | N-myc downstream regulated 1 | 0.0304074 |
| RPS27A | ribosomal protein S27a | 0.0298237 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0285916 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0282265 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0281114 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0275243 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.026913 |
| ANO6 | anoctamin 6 | 0.0267535 |
| PCBP2 | poly(rC) binding protein 2 | 0.0264378 |
| EGFR | epidermal growth factor receptor | 0.0260122 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0256906 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.025617 |
| B2M | beta-2-microglobulin | 0.0254432 |
| MCL1 | myeloid cell leukemia 1 | 0.0253818 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0253517 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0249348 |
| SET | SET nuclear proto-oncogene | 0.0244131 |
| RPL12 | ribosomal protein L12 | 0.0244094 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0243282 |
| KIAA1217 | KIAA1217 | 0.0242983 |
| CD44 | CD44 molecule (Indian blood group) | 0.0236566 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0233742 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0225479 |
| APP | amyloid beta (A4) precursor protein | 0.0223824 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0222193 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0222185 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0221029 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0220379 |
| VIM | vimentin | 0.0219921 |
| EZR | ezrin | 0.0217338 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0216081 |
| VGLL3 | vestigial-like family member 3 | 0.0213481 |
| RBM25 | RNA binding motif protein 25 | 0.0212197 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0211037 |
| MYO5B | myosin VB | 0.0210256 |
| IRS2 | insulin receptor substrate 2 | 0.0208872 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 0.0208094 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0208027 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0206994 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0205968 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0205488 |
| RACK1 | receptor for activated C kinase 1 | 0.0205368 |
| DST | dystonin | 0.0204147 |
| TUFT1 | tuftelin 1 | 0.0202307 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0199145 |
| RPS6 | ribosomal protein S6 | 0.0196641 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0196397 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.0195188 |
| RPS4X | ribosomal protein S4, X-linked | 0.0195077 |
| CALR | calreticulin | 0.0193702 |
| CD109 | CD109 molecule | 0.0191668 |
| USP53 | ubiquitin specific peptidase 53 | 0.0191394 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0188699 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0187295 |
| TNPO1 | transportin 1 | 0.0186794 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0186339 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0186189 |
| RPL13A | ribosomal protein L13a | 0.0185773 |
| TPR | translocated promoter region, nuclear basket protein | 0.0185244 |
| RPS17 | ribosomal protein S17 | 0.0184279 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.336474 |
| FN1 | fibronectin 1 | -0.205266 |
| POTEF | POTE ankyrin domain family, member F | -0.174561 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.143683 |
| ACTG1 | actin gamma 1 | -0.11701 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0881706 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0865109 |
| TMSB10 | thymosin beta 10 | -0.0832886 |
| CCND1 | cyclin D1 | -0.0803821 |
| KRT7 | keratin 7, type II | -0.0790361 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0776012 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0764109 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0732139 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0729652 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0699387 |
| CD2AP | CD2-associated protein | -0.0643972 |
| TPM4 | tropomyosin 4 | -0.0630083 |
| UBC | ubiquitin C | -0.0615433 |
| PKM | pyruvate kinase, muscle | -0.0597126 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0581151 |
| GNAS | GNAS complex locus | -0.0570151 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0567041 |
| S100A10 | S100 calcium binding protein A10 | -0.0557667 |
| RPL8 | ribosomal protein L8 | -0.0550527 |
| TMEM165 | transmembrane protein 165 | -0.0542011 |
| FTL | ferritin, light polypeptide | -0.0535307 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0534258 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0507002 |
| TMEM123 | transmembrane protein 123 | -0.0498222 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0468189 |
| TMEM263 | transmembrane protein 263 | -0.0446319 |
| FBXO32 | F-box protein 32 | -0.043592 |
| CSTB | cystatin B (stefin B) | -0.0434742 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0430881 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0413077 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0410262 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0402513 |
| HLA-B | major histocompatibility complex, class I, B | -0.0398841 |
| MAP1B | microtubule-associated protein 1B | -0.0384758 |
| HDLBP | high density lipoprotein binding protein | -0.0383955 |
| FAM3C | family with sequence similarity 3, member C | -0.0373804 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0373242 |
| RAI14 | retinoic acid induced 14 | -0.0372489 |
| LMAN1 | lectin, mannose-binding, 1 | -0.037031 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0370121 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0368479 |
| RPS23 | ribosomal protein S23 | -0.0357459 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0351766 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0350816 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0343617 |
| KRT8 | keratin 8, type II | -0.0338142 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0336832 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0336609 |
| WASF2 | WAS protein family, member 2 | -0.0336339 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0332073 |
| LMNA | lamin A/C | -0.0330787 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0326823 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0325699 |
| RRBP1 | ribosome binding protein 1 | -0.0325298 |
| KRT18 | keratin 18, type I | -0.0324743 |
| HMGA1 | high mobility group AT-hook 1 | -0.0320992 |
| S100A6 | S100 calcium binding protein A6 | -0.0320719 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0319999 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0315797 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0311666 |
| MCU | mitochondrial calcium uniporter | -0.0309247 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0306267 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0303246 |
| TKT | transketolase | -0.0301589 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0300769 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0298815 |
| MX2 | MX dynamin-like GTPase 2 | -0.02966 |
| ARF1 | ADP-ribosylation factor 1 | -0.0293923 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0291043 |
| RPL32 | ribosomal protein L32 | -0.0289849 |
| RNF213 | ring finger protein 213 | -0.0289264 |
| LDHA | lactate dehydrogenase A | -0.0283318 |
| LMO7 | LIM domain 7 | -0.0280287 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0279064 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0278658 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0276561 |
| CTSB | cathepsin B | -0.0275943 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0274994 |
| SEC24D | SEC24 family member D | -0.027458 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.027414 |
| ZNF217 | zinc finger protein 217 | -0.02736 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0273221 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0270848 |
| H1-0 | H1.0 linker histone | -0.0269528 |
| FBXO34 | F-box protein 34 | -0.0269319 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0264906 |
| MSI2 | musashi RNA-binding protein 2 | -0.0264619 |
| HLA-A | major histocompatibility complex, class I, A | -0.0263177 |
| MAP4 | microtubule-associated protein 4 | -0.0262433 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0262306 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0261052 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0257719 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.025179 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0251079 |
| TRAM1 | translocation associated membrane protein 1 | -0.0249631 |
