| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bimatoprost perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bimatoprost_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PM20D1 | peptidase M20 domain containing 1 | 0.199113 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.118876 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0966964 |
| PDE10A | phosphodiesterase 10A | 0.0933107 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0827948 |
| DST | dystonin | 0.078854 |
| DNER | delta/notch-like EGF repeat containing | 0.0721063 |
| SMAD2 | SMAD family member 2 | 0.0695619 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0681741 |
| MCL1 | myeloid cell leukemia 1 | 0.0677714 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0654023 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0633908 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0628916 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0628131 |
| INTS6 | integrator complex subunit 6 | 0.0608469 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0608265 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.060281 |
| FMNL2 | formin-like 2 | 0.0591803 |
| VCL | vinculin | 0.0555303 |
| KYNU | kynureninase | 0.0552565 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0531686 |
| AUTS2 | autism susceptibility candidate 2 | 0.0503519 |
| UBC | ubiquitin C | 0.0480049 |
| CHL1 | cell adhesion molecule L1-like | 0.0442389 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0412532 |
| RAD51B | RAD51 paralog B | 0.0401537 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0377893 |
| HDAC4 | histone deacetylase 4 | 0.0362902 |
| FAM107B | family with sequence similarity 107, member B | 0.0344489 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0332879 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0330438 |
| PRELID2 | PRELI domain containing 2 | 0.0324725 |
| XYLT1 | xylosyltransferase I | 0.0324453 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0318083 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0310984 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0308474 |
| AEBP2 | AE binding protein 2 | 0.028811 |
| CUX1 | cut-like homeobox 1 | 0.0284228 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0283338 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0281191 |
| RPS27A | ribosomal protein S27a | 0.0279739 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0278528 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0278095 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.027452 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0267895 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | 0.0264509 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 0.0261067 |
| PDE7B | phosphodiesterase 7B | 0.0260823 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0254211 |
| DENND1A | DENN/MADD domain containing 1A | 0.0253408 |
| CTBP2 | C-terminal binding protein 2 | 0.0249172 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | 0.0247417 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.024675 |
| NRXN3 | neurexin 3 | 0.0241191 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.023705 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0236732 |
| HMGA2 | high mobility group AT-hook 2 | 0.0231976 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0231641 |
| MGST1 | microsomal glutathione S-transferase 1 | 0.0227507 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | 0.0226608 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0224908 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0223 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0219584 |
| GDA | guanine deaminase | 0.0218477 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0217486 |
| GLRX | glutaredoxin (thioltransferase) | 0.021423 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0213539 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0213186 |
| MAP7 | microtubule-associated protein 7 | 0.0211754 |
| IRS2 | insulin receptor substrate 2 | 0.021149 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0209888 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0208075 |
| AADAC | arylacetamide deacetylase | 0.0206211 |
| GPC6 | glypican 6 | 0.0204602 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0203696 |
| RCOR1 | REST corepressor 1 | 0.02023 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.020103 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0199861 |
| PCBP2 | poly(rC) binding protein 2 | 0.0199455 |
| RAB31 | RAB31, member RAS oncogene family | 0.0197193 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0196939 |
| FNIP1 | folliculin interacting protein 1 | 0.0195126 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0193166 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0192928 |
| FRY | furry homolog (Drosophila) | 0.0186844 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 | 0.0185667 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0184252 |
| OXSR1 | oxidative stress responsive 1 | 0.0183813 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0183775 |
| BMP6 | bone morphogenetic protein 6 | 0.0182011 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0180689 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0177144 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0173664 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0170955 |
| NRDC | nardilysin convertase | 0.0170531 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0170007 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0169597 |
| PCDH15 | protocadherin-related 15 | 0.0168315 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.0167413 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0167412 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | -0.169977 |
| EFNA5 | ephrin-A5 | -0.162599 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.157389 |
| ASPH | aspartate beta-hydroxylase | -0.125908 |
| NRCAM | neuronal cell adhesion molecule | -0.117583 |
| TXNRD1 | thioredoxin reductase 1 | -0.114678 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.105954 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0973407 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0929443 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0854297 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0834692 |
| NEK7 | NIMA-related kinase 7 | -0.0805026 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0792277 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0736917 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0645076 |
| RTN4 | reticulon 4 | -0.0636354 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0636129 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0626002 |
| TNPO1 | transportin 1 | -0.0612669 |
| FN1 | fibronectin 1 | -0.0586276 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0531986 |
| CD109 | CD109 molecule | -0.053191 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0522847 |
| CTSC | cathepsin C | -0.0521814 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0495139 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0487055 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0482372 |
| TMSB10 | thymosin beta 10 | -0.0464735 |
| MFF | mitochondrial fission factor | -0.0456862 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | -0.0453624 |
| RPS6 | ribosomal protein S6 | -0.0444255 |
| BMERB1 | bMERB domain containing 1 | -0.0439068 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0425323 |
| RPL35A | ribosomal protein L35a | -0.0419614 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0416042 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0413955 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0411593 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0409631 |
| MAP1B | microtubule-associated protein 1B | -0.0394044 |
| CENPF | centromere protein F, 350/400kDa | -0.0393284 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0381687 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.037688 |
| AGFG1 | ArfGAP with FG repeats 1 | -0.0366451 |
| RPS24 | ribosomal protein S24 | -0.0365567 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0364341 |
| PTGR1 | prostaglandin reductase 1 | -0.0358128 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0339458 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0331649 |
| FTL | ferritin, light polypeptide | -0.0318729 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.031645 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0310356 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0309696 |
| ENAH | enabled homolog (Drosophila) | -0.0308197 |
| PYGL | phosphorylase, glycogen, liver | -0.0306172 |
| RPLP1 | ribosomal protein, large, P1 | -0.0304719 |
| PGK1 | phosphoglycerate kinase 1 | -0.0304371 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0303144 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0301107 |
| GNAS | GNAS complex locus | -0.0301102 |
| PALLD | palladin, cytoskeletal associated protein | -0.0299295 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0297874 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0296178 |
| OSMR | oncostatin M receptor | -0.0295942 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.029532 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | -0.0294582 |
| ZNF292 | zinc finger protein 292 | -0.0292189 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0286469 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0284234 |
| CDK6 | cyclin-dependent kinase 6 | -0.0281439 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0281378 |
| MYOF | myoferlin | -0.027826 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0277909 |
| OGA | O-GlcNAcase | -0.0275975 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0272866 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0272271 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0270832 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0270526 |
| MKI67 | marker of proliferation Ki-67 | -0.0270524 |
| SLFN5 | schlafen family member 5 | -0.0268866 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0260111 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0259908 |
| SEPTIN10 | septin 10 | -0.0257534 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0255476 |
| RPL26 | ribosomal protein L26 | -0.0255062 |
| RPS19 | ribosomal protein S19 | -0.0254224 |
| RPL23 | ribosomal protein L23 | -0.0253488 |
| RPS21 | ribosomal protein S21 | -0.025301 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0250702 |
| RRBP1 | ribosome binding protein 1 | -0.0245915 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0245586 |
| GPRIN3 | GPRIN family member 3 | -0.0245576 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0243896 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | -0.0243276 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0242778 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.0242645 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0242041 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0241971 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0240597 |
| GOLGA4 | golgin A4 | -0.0239808 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | -0.0239672 |
