| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bimatoprost perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bimatoprost_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PHIP | pleckstrin homology domain interacting protein | 0.1014 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0974931 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0861508 |
| PCDH9 | protocadherin 9 | 0.0710229 |
| JMJD1C | jumonji domain containing 1C | 0.0707221 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0688696 |
| APP | amyloid beta (A4) precursor protein | 0.0632107 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0622415 |
| SMYD3 | SET and MYND domain containing 3 | 0.0581477 |
| CALR | calreticulin | 0.0554408 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0544795 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0536986 |
| ANK2 | ankyrin 2, neuronal | 0.0521461 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0517195 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0510801 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0500367 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0499632 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0497396 |
| STAG2 | stromal antigen 2 | 0.0495173 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0491618 |
| PTMA | prothymosin, alpha | 0.0482405 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0480843 |
| RCOR1 | REST corepressor 1 | 0.0476736 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.046662 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0462201 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0459882 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0443115 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0413299 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0404905 |
| OGA | O-GlcNAcase | 0.0388164 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0382012 |
| ZNF451 | zinc finger protein 451 | 0.0381061 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0378797 |
| NTM | neurotrimin | 0.0365549 |
| WDR43 | WD repeat domain 43 | 0.0364941 |
| ZNF292 | zinc finger protein 292 | 0.0360429 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0359262 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0355016 |
| HMGB2 | high mobility group box 2 | 0.0353054 |
| NHSL1 | NHS-like 1 | 0.0349247 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0344523 |
| MRPS30 | mitochondrial ribosomal protein S30 | 0.0343556 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0343026 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.034236 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0338246 |
| RBM33 | RNA binding motif protein 33 | 0.033771 |
| CTBP2 | C-terminal binding protein 2 | 0.0331895 |
| CDH19 | cadherin 19, type 2 | 0.0329549 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0328334 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.032522 |
| PRTG | protogenin | 0.0321847 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0317814 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0315847 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0312265 |
| SP3 | Sp3 transcription factor | 0.0308945 |
| FNBP1L | formin binding protein 1-like | 0.0307554 |
| ATXN2 | ataxin 2 | 0.0307284 |
| PARD3 | par-3 family cell polarity regulator | 0.0306506 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0304278 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0303462 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0302063 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0290939 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.028979 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.0287628 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0284796 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0283145 |
| HDAC9 | histone deacetylase 9 | 0.0281715 |
| RBM39 | RNA binding motif protein 39 | 0.0279739 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0279314 |
| CYRIB | CYFIP related Rac1 interactor B | 0.0279293 |
| SPAG9 | sperm associated antigen 9 | 0.0278755 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0278364 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0277936 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.027766 |
| RBM25 | RNA binding motif protein 25 | 0.0275207 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0271649 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0271164 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0267587 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | 0.0264975 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0263664 |
| PSMD8 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 | 0.0261005 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0260296 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0258058 |
| XPO1 | exportin 1 | 0.0256923 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.025679 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.025615 |
| MATR3 | matrin 3 | 0.025362 |
| ABI2 | abl-interactor 2 | 0.0252774 |
| ZNF608 | zinc finger protein 608 | 0.0251716 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0250156 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0249483 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 0.024805 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0245124 |
| TENM2 | teneurin transmembrane protein 2 | 0.0244905 |
| SBF2 | SET binding factor 2 | 0.0242282 |
| USP53 | ubiquitin specific peptidase 53 | 0.0240677 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0240037 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0239146 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0238325 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0237773 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.191561 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0778255 |
| TMSB10 | thymosin beta 10 | -0.0728052 |
| POTEF | POTE ankyrin domain family, member F | -0.0714473 |
| RPS6 | ribosomal protein S6 | -0.0662958 |
| PFN1 | profilin 1 | -0.0653336 |
| DST | dystonin | -0.0635515 |
| PEG10 | paternally expressed 10 | -0.0495777 |
| CADM2 | cell adhesion molecule 2 | -0.0488503 |
| SYT1 | synaptotagmin I | -0.0470406 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0466498 |
| NRG1 | neuregulin 1 | -0.0444018 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0441174 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0434048 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0425968 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.041021 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0408228 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0395418 |
| MEIS2 | Meis homeobox 2 | -0.0394348 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0394338 |
| RPL23 | ribosomal protein L23 | -0.0390473 |
| ACTG1 | actin gamma 1 | -0.0384658 |
| FTL | ferritin, light polypeptide | -0.0381763 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0374542 |
| FOXP2 | forkhead box P2 | -0.0357008 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0355209 |
| MAP1B | microtubule-associated protein 1B | -0.0350768 |
| RPS16 | ribosomal protein S16 | -0.0334068 |
| FAT1 | FAT atypical cadherin 1 | -0.0331352 |
| TOX | thymocyte selection-associated high mobility group box | -0.0325199 |
| SLC38A2 | solute carrier family 38, member 2 | -0.031882 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.031547 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0312599 |
| RPLP1 | ribosomal protein, large, P1 | -0.0311633 |
| FAM171B | family with sequence similarity 171, member B | -0.0309364 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0307896 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0307285 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.030071 |
| HMCN1 | hemicentin 1 | -0.0297357 |
| RPS19 | ribosomal protein S19 | -0.029326 |
| FGF13 | fibroblast growth factor 13 | -0.0289922 |
| RPS21 | ribosomal protein S21 | -0.0289017 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0283841 |
| MPG | N-methylpurine-DNA glycosylase | -0.0281497 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0281308 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0281222 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0280693 |
| TUBA1B | tubulin, alpha 1b | -0.0279495 |
| AHNAK | AHNAK nucleoprotein | -0.0273057 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.0272253 |
| RPL19 | ribosomal protein L19 | -0.0272127 |
| RPL12 | ribosomal protein L12 | -0.0271296 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0269035 |
| EMP1 | epithelial membrane protein 1 | -0.0268523 |
| RPS5 | ribosomal protein S5 | -0.0265447 |
| SIK2 | salt-inducible kinase 2 | -0.0265403 |
| TENM3 | teneurin transmembrane protein 3 | -0.0263359 |
| RPLP2 | ribosomal protein, large, P2 | -0.0260495 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0257274 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0251428 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0251158 |
| LYST | lysosomal trafficking regulator | -0.0248772 |
| SHROOM3 | shroom family member 3 | -0.024874 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0240735 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.023841 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.023261 |
| SCFD1 | sec1 family domain containing 1 | -0.0232541 |
| S100A10 | S100 calcium binding protein A10 | -0.0231219 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0231139 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0230014 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.02293 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0225677 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0225297 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0223808 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0222529 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0218845 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0214531 |
| TBC1D32 | TBC1 domain family, member 32 | -0.0213708 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0212184 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.021186 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0211386 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0209832 |
| RPL31 | ribosomal protein L31 | -0.0207901 |
| PDCD5 | programmed cell death 5 | -0.0207708 |
| S100A9 | S100 calcium binding protein A9 | -0.0206308 |
| CBX3 | chromobox homolog 3 | -0.0205739 |
| SERF2 | small EDRK-rich factor 2 | -0.0203631 |
| SEMA3E | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E | -0.0203021 |
| RPL8 | ribosomal protein L8 | -0.0202053 |
| GNAS | GNAS complex locus | -0.0200442 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0200231 |
| RPL34 | ribosomal protein L34 | -0.0198913 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0195765 |
| PRORP | protein only RNase P catalytic subunit | -0.0195079 |
| ACTN4 | actinin, alpha 4 | -0.0193663 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0193508 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0191274 |
| DEK | DEK proto-oncogene | -0.0191038 |
| FN1 | fibronectin 1 | -0.0190453 |
| USH2A | Usher syndrome 2A (autosomal recessive, mild) | -0.0190313 |
