| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bimatoprost perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bimatoprost_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB4X | thymosin beta 4, X-linked | 0.1124 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0860265 |
| EZR | ezrin | 0.0779158 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0746695 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0701651 |
| ENO1 | enolase 1, (alpha) | 0.0658264 |
| PTMA | prothymosin, alpha | 0.0656335 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0653704 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.059738 |
| PGK1 | phosphoglycerate kinase 1 | 0.0500013 |
| ZNF608 | zinc finger protein 608 | 0.0490794 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0458708 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0443625 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0443016 |
| SQSTM1 | sequestosome 1 | 0.0399655 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0395333 |
| RPS12 | ribosomal protein S12 | 0.039228 |
| LDHA | lactate dehydrogenase A | 0.038012 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0371898 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0370156 |
| ANXA1 | annexin A1 | 0.0359889 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0338278 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0333071 |
| GOLGA4 | golgin A4 | 0.0329903 |
| SPAG9 | sperm associated antigen 9 | 0.0321961 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0311665 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0307433 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0304711 |
| VCL | vinculin | 0.0304339 |
| CANX | calnexin | 0.0291739 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0290619 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0283074 |
| UBC | ubiquitin C | 0.0275626 |
| APP | amyloid beta (A4) precursor protein | 0.0275002 |
| RNF145 | ring finger protein 145 | 0.0265689 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0262778 |
| RPL7 | ribosomal protein L7 | 0.0259832 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0258647 |
| JMJD1C | jumonji domain containing 1C | 0.025503 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0249181 |
| DST | dystonin | 0.0241136 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0235296 |
| FAT1 | FAT atypical cadherin 1 | 0.02337 |
| TMF1 | TATA element modulatory factor 1 | 0.0232921 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0232564 |
| SERINC3 | serine incorporator 3 | 0.0231411 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.023098 |
| RAD50 | RAD50 homolog (S. cerevisiae) | 0.0230941 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0229396 |
| CCDC68 | coiled-coil domain containing 68 | 0.0228554 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0227391 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0225903 |
| NDRG1 | N-myc downstream regulated 1 | 0.0225226 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0224862 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0224288 |
| RPS6 | ribosomal protein S6 | 0.0223444 |
| OGA | O-GlcNAcase | 0.0221489 |
| GOLGB1 | golgin B1 | 0.0220104 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0218779 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0218153 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0212067 |
| PLK2 | polo-like kinase 2 | 0.0211707 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0210975 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0209633 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.020959 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0209575 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0209279 |
| RO60 | Ro60, Y RNA binding protein | 0.020626 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0206212 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.020521 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0203353 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0202185 |
| CCNC | cyclin C | 0.0202016 |
| B2M | beta-2-microglobulin | 0.0201019 |
| SMAP1 | small ArfGAP 1 | 0.0200166 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0199489 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0198193 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0197856 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0194188 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0192932 |
| MACROD2 | MACRO domain containing 2 | 0.019262 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.0192424 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0192107 |
| YTHDC1 | YTH domain containing 1 | 0.0191254 |
| ZNF638 | zinc finger protein 638 | 0.0191079 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0190943 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0190903 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0190005 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0189817 |
| AMOTL2 | angiomotin like 2 | 0.0189393 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0189381 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | 0.0188974 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0187482 |
| SON | SON DNA binding protein | 0.0185399 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0185201 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0184991 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0183968 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.0183002 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0182308 |
| DUSP6 | dual specificity phosphatase 6 | 0.0181253 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.211819 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.154088 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.125862 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.120931 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.108116 |
| NBEA | neurobeachin | -0.0923569 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0812609 |
| DPYD | dihydropyrimidine dehydrogenase | -0.075066 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0688728 |
| FOXP1 | forkhead box P1 | -0.0585324 |
| RPL35A | ribosomal protein L35a | -0.0582351 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0541923 |
| NAV2 | neuron navigator 2 | -0.05126 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0498223 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0484462 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | -0.046402 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0457394 |
| GLI2 | GLI family zinc finger 2 | -0.0455793 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0449405 |
| FHIT | fragile histidine triad | -0.0423739 |
| CCND1 | cyclin D1 | -0.0402906 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0402576 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0385985 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0369072 |
| PDE7B | phosphodiesterase 7B | -0.0360089 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0347622 |
| IGF2 | insulin-like growth factor 2 | -0.034686 |
| EFNA5 | ephrin-A5 | -0.0332791 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0326511 |
| RPL34 | ribosomal protein L34 | -0.0326292 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0325651 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0325598 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0323332 |
| DIAPH3 | diaphanous-related formin 3 | -0.0315848 |
| S100A4 | S100 calcium binding protein A4 | -0.0314844 |
| NEBL | nebulette | -0.031449 |
| GSE1 | Gse1 coiled-coil protein | -0.0308008 |
| INTS6 | integrator complex subunit 6 | -0.0304786 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0303291 |
| DENND1A | DENN/MADD domain containing 1A | -0.0303096 |
| IRX2 | iroquois homeobox 2 | -0.0294265 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0293043 |
| HJURP | Holliday junction recognition protein | -0.0292557 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0291683 |
| NFIA | nuclear factor I/A | -0.0290766 |
| RPL32 | ribosomal protein L32 | -0.0286486 |
| CENPE | centromere protein E, 312kDa | -0.0281502 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0277327 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0277296 |
| ZNF609 | zinc finger protein 609 | -0.0276288 |
| RPS23 | ribosomal protein S23 | -0.0275561 |
| RPS8 | ribosomal protein S8 | -0.027299 |
| GNAS | GNAS complex locus | -0.0270183 |
| FUS | FUS RNA binding protein | -0.0270058 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 | -0.0264855 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0262077 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0258171 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0256582 |
| BMP10 | bone morphogenetic protein 10 | -0.02559 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0255728 |
| TMEM65 | transmembrane protein 65 | -0.0254371 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | -0.0248573 |
| RPL26 | ribosomal protein L26 | -0.0248143 |
| SLC38A2 | solute carrier family 38, member 2 | -0.024706 |
| RPS11 | ribosomal protein S11 | -0.0244593 |
| TCF12 | transcription factor 12 | -0.0239448 |
| CENPF | centromere protein F, 350/400kDa | -0.0238123 |
| PARD3 | par-3 family cell polarity regulator | -0.0235725 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | -0.0233015 |
| RPL19 | ribosomal protein L19 | -0.023269 |
| MEIS2 | Meis homeobox 2 | -0.0232006 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0231877 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0229988 |
| PRSS23 | protease, serine, 23 | -0.0225018 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0221928 |
| PKM | pyruvate kinase, muscle | -0.0221229 |
| EBNA1BP2 | EBNA1 binding protein 2 | -0.0220483 |
| RPS21 | ribosomal protein S21 | -0.0219947 |
| CRPPA | CDP-L-ribitol pyrophosphorylase A | -0.021984 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0218931 |
| RYR2 | ryanodine receptor 2 (cardiac) | -0.021808 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase | -0.0216232 |
| RPS24 | ribosomal protein S24 | -0.0215964 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | -0.0213831 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0212919 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0212748 |
| RAD18 | RAD18 E3 ubiquitin protein ligase | -0.0212638 |
| COMMD10 | COMM domain containing 10 | -0.0212564 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0211353 |
| GPATCH2L | G patch domain containing 2-like | -0.0207591 |
| PFN1 | profilin 1 | -0.0206448 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0205918 |
| DHFR | dihydrofolate reductase | -0.0205128 |
| POTEF | POTE ankyrin domain family, member F | -0.0205009 |
| MELTF | melanotransferrin | -0.0204847 |
| RCOR1 | REST corepressor 1 | -0.0204367 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.0204308 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0203789 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0203362 |
| CNTNAP3B | contactin associated protein-like 3B | -0.0203131 |
