| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bimatoprost perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bimatoprost_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | 0.125208 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0977099 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.088355 |
| MT2A | metallothionein 2A | 0.0691935 |
| BICC1 | BicC family RNA binding protein 1 | 0.0662387 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0646441 |
| MSN | moesin | 0.0569812 |
| FN1 | fibronectin 1 | 0.0492822 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0461609 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0458731 |
| STC1 | stanniocalcin 1 | 0.0391859 |
| SDC4 | syndecan 4 | 0.0386879 |
| FKBP5 | FK506 binding protein 5 | 0.0385236 |
| RPS12 | ribosomal protein S12 | 0.0372878 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0363078 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.036205 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.035255 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.035231 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.03462 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0329665 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0328694 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.032275 |
| LDHA | lactate dehydrogenase A | 0.0320297 |
| KYNU | kynureninase | 0.0312445 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0301208 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0294713 |
| INHBA | inhibin, beta A | 0.0293436 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0289267 |
| AHR | aryl hydrocarbon receptor | 0.0286512 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0277883 |
| MCL1 | myeloid cell leukemia 1 | 0.0276197 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0257338 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.025417 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0242323 |
| ZNF608 | zinc finger protein 608 | 0.0231422 |
| DUSP5 | dual specificity phosphatase 5 | 0.0230789 |
| TOP1 | topoisomerase (DNA) I | 0.0230697 |
| JAK2 | Janus kinase 2 | 0.0229847 |
| VCL | vinculin | 0.0229388 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0227775 |
| HMGA2 | high mobility group AT-hook 2 | 0.0221567 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0208628 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0202249 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0199156 |
| RPLP0 | ribosomal protein, large, P0 | 0.0197076 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0193641 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0192931 |
| MT1X | metallothionein 1X | 0.0191159 |
| TGM2 | transglutaminase 2 | 0.0188547 |
| KLF6 | Kruppel-like factor 6 | 0.018691 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0183057 |
| APP | amyloid beta (A4) precursor protein | 0.0181111 |
| B2M | beta-2-microglobulin | 0.0173078 |
| NAV2 | neuron navigator 2 | 0.0172024 |
| TUT7 | terminal uridylyl transferase 7 | 0.0169474 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0169036 |
| VMP1 | vacuole membrane protein 1 | 0.016902 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0168528 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0168437 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0167879 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0164817 |
| CTSA | cathepsin A | 0.0163462 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0162227 |
| DCBLD1 | discoidin, CUB and LCCL domain containing 1 | 0.0161998 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0161501 |
| SET | SET nuclear proto-oncogene | 0.0160759 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0160716 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0159428 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0158323 |
| ASPH | aspartate beta-hydroxylase | 0.0157979 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0155677 |
| RPS3 | ribosomal protein S3 | 0.0153758 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0152709 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0148984 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0147822 |
| TPM3 | tropomyosin 3 | 0.0147807 |
| RPL7 | ribosomal protein L7 | 0.0146096 |
| PCBP3 | poly(rC) binding protein 3 | 0.0145409 |
| ENO1 | enolase 1, (alpha) | 0.0144861 |
| NRP1 | neuropilin 1 | 0.0144164 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 0.0144095 |
| RPL9 | ribosomal protein L9 | 0.0142046 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0140758 |
| EZR | ezrin | 0.0140075 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0139023 |
| SAA2 | serum amyloid A2 | 0.0138477 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0137771 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0137708 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0137627 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0137201 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0137077 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0136464 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0136117 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.013545 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0135358 |
| RCL1 | RNA terminal phosphate cyclase-like 1 | 0.0133501 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0133076 |
| CCNL1 | cyclin L1 | 0.0132639 |
| NTN4 | netrin 4 | 0.0132562 |
| MKI67 | marker of proliferation Ki-67 | 0.0131682 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FRMD4A | FERM domain containing 4A | -0.203438 |
| VIM | vimentin | -0.19684 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.158724 |
| PDE10A | phosphodiesterase 10A | -0.153432 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.131876 |
| CADM1 | cell adhesion molecule 1 | -0.116946 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.11559 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.113441 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.112941 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.110803 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0949266 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0776711 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0716821 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0714939 |
| IER3 | immediate early response 3 | -0.0714098 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0683967 |
| HLA-B | major histocompatibility complex, class I, B | -0.0673244 |
| NDRG1 | N-myc downstream regulated 1 | -0.0667652 |
| FTL | ferritin, light polypeptide | -0.0664195 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.064476 |
| RAI14 | retinoic acid induced 14 | -0.0610525 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0587308 |
| CDH13 | cadherin 13 | -0.0581489 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.054981 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0546446 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.054087 |
| DST | dystonin | -0.0538587 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0502 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0481532 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0465081 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0456072 |
| DIAPH2 | diaphanous-related formin 2 | -0.0455464 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0453942 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.045147 |
| MMP12 | matrix metallopeptidase 12 | -0.0446679 |
| ZNF292 | zinc finger protein 292 | -0.0436693 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0429497 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0421033 |
| VCAN | versican | -0.0412901 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0409711 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0403969 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0393006 |
| CCBE1 | collagen and calcium binding EGF domains 1 | -0.0391122 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0387981 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0384336 |
| COL1A1 | collagen, type I, alpha 1 | -0.0382716 |
| ADM | adrenomedullin | -0.0381104 |
| NAV1 | neuron navigator 1 | -0.0374099 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0372382 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0369475 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0365742 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0357088 |
| TMSB10 | thymosin beta 10 | -0.0349505 |
| GNAS | GNAS complex locus | -0.034841 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0344295 |
| HLA-A | major histocompatibility complex, class I, A | -0.0344199 |
| EGR1 | early growth response 1 | -0.0342206 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0339062 |
| NCKAP5 | NCK-associated protein 5 | -0.033476 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0329652 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0328475 |
| VEGFA | vascular endothelial growth factor A | -0.0325131 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0321144 |
| GOLGA4 | golgin A4 | -0.0312886 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0309739 |
| PHF21A | PHD finger protein 21A | -0.0308378 |
| PLIN2 | perilipin 2 | -0.0307354 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0305704 |
| EGFR | epidermal growth factor receptor | -0.0301538 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0300497 |
| MORF4L2 | mortality factor 4 like 2 | -0.029922 |
| BNC2 | basonuclin 2 | -0.0297833 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0288077 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0286857 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.028667 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0284884 |
| TENM2 | teneurin transmembrane protein 2 | -0.0280972 |
| MAP4 | microtubule-associated protein 4 | -0.0280913 |
| KIF13A | kinesin family member 13A | -0.0280653 |
| LRRC7 | leucine rich repeat containing 7 | -0.0278027 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0273595 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0273077 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0269599 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0269117 |
| RRBP1 | ribosome binding protein 1 | -0.0267176 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0266691 |
| NRN1 | neuritin 1 | -0.0260292 |
| AHNAK | AHNAK nucleoprotein | -0.0258435 |
| GLIS3 | GLIS family zinc finger 3 | -0.0256075 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0253732 |
| CTSD | cathepsin D | -0.0252747 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0252436 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0251742 |
| COL5A1 | collagen, type V, alpha 1 | -0.0251562 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0250219 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0249347 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0249049 |
| PKM | pyruvate kinase, muscle | -0.0248078 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0247811 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0247451 |
