| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bimatoprost perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bimatoprost_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.120495 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0924539 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0916518 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0703451 |
| PRELID2 | PRELI domain containing 2 | 0.0673855 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0658347 |
| CDH13 | cadherin 13 | 0.0645119 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0625477 |
| FN1 | fibronectin 1 | 0.0594373 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0575676 |
| KYNU | kynureninase | 0.0531693 |
| FNIP1 | folliculin interacting protein 1 | 0.052945 |
| VCL | vinculin | 0.0521541 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0498207 |
| ENO1 | enolase 1, (alpha) | 0.0497994 |
| NAV2 | neuron navigator 2 | 0.047039 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0464975 |
| RAD51B | RAD51 paralog B | 0.0462219 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0457907 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.043053 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0429368 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0428867 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0425679 |
| CANX | calnexin | 0.0422289 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0421673 |
| MSN | moesin | 0.0419983 |
| EGFR | epidermal growth factor receptor | 0.04187 |
| INTS6 | integrator complex subunit 6 | 0.0416955 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0416459 |
| ANO6 | anoctamin 6 | 0.041219 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0411458 |
| DST | dystonin | 0.0393251 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0382226 |
| HIP1 | huntingtin interacting protein 1 | 0.0381584 |
| EXOC6B | exocyst complex component 6B | 0.0362036 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0361949 |
| CLIC4 | chloride intracellular channel 4 | 0.0357665 |
| FAM20C | family with sequence similarity 20, member C | 0.0344775 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0339347 |
| ATXN1 | ataxin 1 | 0.0331645 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0329596 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0322973 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0322298 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0321583 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0319274 |
| MCL1 | myeloid cell leukemia 1 | 0.0318651 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0317895 |
| ZNF638 | zinc finger protein 638 | 0.0316662 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0314354 |
| GLIS3 | GLIS family zinc finger 3 | 0.0314014 |
| MYOF | myoferlin | 0.0311328 |
| NRXN3 | neurexin 3 | 0.0310037 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0308197 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0308087 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0304208 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0302664 |
| FAM13A | family with sequence similarity 13, member A | 0.029895 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0295141 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0293524 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0292744 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0284897 |
| RUNX1 | runt-related transcription factor 1 | 0.0283812 |
| TNS3 | tensin 3 | 0.0282995 |
| CUX1 | cut-like homeobox 1 | 0.0280161 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0277787 |
| CSMD2 | CUB and Sushi multiple domains 2 | 0.027689 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0274868 |
| JAK1 | Janus kinase 1 | 0.0274614 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0272062 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0268496 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0268414 |
| LAMB1 | laminin, beta 1 | 0.0266498 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0261895 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0260116 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | 0.0258992 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0258251 |
| VEGFC | vascular endothelial growth factor C | 0.0258246 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0257585 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | 0.025706 |
| NAV1 | neuron navigator 1 | 0.0254876 |
| JPH2 | junctophilin 2 | 0.0254384 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0249052 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.024593 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0244904 |
| DENND1A | DENN/MADD domain containing 1A | 0.024478 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0244616 |
| HMGA2 | high mobility group AT-hook 2 | 0.0243616 |
| PRKCA | protein kinase C, alpha | 0.0243114 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0242592 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0241042 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0240292 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0239979 |
| HDAC9 | histone deacetylase 9 | 0.0239923 |
| NF1 | neurofibromin 1 | 0.0238692 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0237664 |
| CCDC18 | coiled-coil domain containing 18 | 0.0236286 |
| KDM3B | lysine (K)-specific demethylase 3B | 0.0235978 |
| ANLN | anillin, actin binding protein | 0.0235917 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0235026 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0233989 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.227015 |
| TMSB10 | thymosin beta 10 | -0.216836 |
| MT2A | metallothionein 2A | -0.16954 |
| HLA-B | major histocompatibility complex, class I, B | -0.147616 |
| VIM | vimentin | -0.145599 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.132385 |
| NDRG1 | N-myc downstream regulated 1 | -0.11297 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.102322 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.101339 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0828277 |
| FTL | ferritin, light polypeptide | -0.0767699 |
| RPL35A | ribosomal protein L35a | -0.058794 |
| CADM1 | cell adhesion molecule 1 | -0.0557153 |
| S100A9 | S100 calcium binding protein A9 | -0.0523424 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0516931 |
| RPL34 | ribosomal protein L34 | -0.0514192 |
| LOXL2 | lysyl oxidase-like 2 | -0.0502674 |
| HLA-C | major histocompatibility complex, class I, C | -0.0467695 |
| RTN4 | reticulon 4 | -0.0466814 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0458311 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0453808 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0440248 |
| B2M | beta-2-microglobulin | -0.0440243 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0430823 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.041443 |
| TAGLN2 | transgelin 2 | -0.0402561 |
| H3-3B | H3.3 histone B | -0.0393383 |
| RPLP1 | ribosomal protein, large, P1 | -0.0391385 |
| MAP4 | microtubule-associated protein 4 | -0.0377881 |
| MT1X | metallothionein 1X | -0.0376923 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0371341 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0369861 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0362402 |
| PTMA | prothymosin, alpha | -0.0360263 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0353672 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0350258 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.034845 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0342382 |
| RPLP2 | ribosomal protein, large, P2 | -0.0340389 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0339052 |
| SRPK2 | SRSF protein kinase 2 | -0.0339004 |
| ANXA2 | annexin A2 | -0.0338567 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0335572 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0330502 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0330397 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0325715 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0324151 |
| RPS6 | ribosomal protein S6 | -0.0322874 |
| SERF2 | small EDRK-rich factor 2 | -0.0321369 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.032016 |
| CLTC | clathrin, heavy chain (Hc) | -0.0319405 |
| RPL23 | ribosomal protein L23 | -0.0319397 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0313733 |
| RPL31 | ribosomal protein L31 | -0.0312797 |
| COL1A2 | collagen, type I, alpha 2 | -0.031218 |
| RPS17 | ribosomal protein S17 | -0.0310465 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0309503 |
| SETD5 | SET domain containing 5 | -0.030831 |
| RPL36 | ribosomal protein L36 | -0.0305583 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0299251 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0296218 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0295402 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0294756 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0293225 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0292042 |
| RPL37 | ribosomal protein L37 | -0.0289779 |
| PMM2 | phosphomannomutase 2 | -0.0289266 |
| RNF24 | ring finger protein 24 | -0.0287778 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0286358 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0285169 |
| SNX6 | sorting nexin 6 | -0.0276227 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.027608 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0275784 |
| SDC4 | syndecan 4 | -0.0272361 |
| RPS19 | ribosomal protein S19 | -0.0272194 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0263633 |
| WTAP | Wilms tumor 1 associated protein | -0.0263207 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | -0.0261785 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0261758 |
| ACTN4 | actinin, alpha 4 | -0.0258818 |
| CUL3 | cullin 3 | -0.0258623 |
| RPS23 | ribosomal protein S23 | -0.0257436 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0256228 |
| TXNIP | thioredoxin interacting protein | -0.0255831 |
| RPL5 | ribosomal protein L5 | -0.0254762 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.025283 |
| TPM4 | tropomyosin 4 | -0.0252825 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0249521 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0248229 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0246299 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0246072 |
| SUCO | SUN domain containing ossification factor | -0.0245427 |
| RPL11 | ribosomal protein L11 | -0.024408 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0242279 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | -0.0241266 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0237774 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0234223 |
| RPL36A | ribosomal protein L36a | -0.0234046 |
| RARS1 | arginyl-tRNA synthetase 1 | -0.023404 |
| COL1A1 | collagen, type I, alpha 1 | -0.0233954 |
