| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bimatoprost perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bimatoprost_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0860903 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0584473 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0566439 |
| SQSTM1 | sequestosome 1 | 0.0532942 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0461839 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0445112 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0443389 |
| DST | dystonin | 0.0438779 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0437674 |
| RIGI | RNA sensor RIG-I | 0.0399156 |
| PHF20 | PHD finger protein 20 | 0.0370994 |
| ANXA1 | annexin A1 | 0.037069 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0361295 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0359364 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0324603 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0295111 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.026672 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0262332 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.0261308 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0260014 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0259167 |
| TXNIP | thioredoxin interacting protein | 0.025913 |
| MYO9A | myosin IXA | 0.025543 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0251987 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0247589 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.0247219 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.024444 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0243491 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0241195 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0239187 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0236227 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0236051 |
| IER3 | immediate early response 3 | 0.0235058 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0231479 |
| LAMB1 | laminin, beta 1 | 0.0228918 |
| TCF12 | transcription factor 12 | 0.0225851 |
| UBC | ubiquitin C | 0.0224893 |
| SP100 | SP100 nuclear antigen | 0.0223548 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0222117 |
| CCND3 | cyclin D3 | 0.0217937 |
| CCND1 | cyclin D1 | 0.021668 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0216219 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0213832 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0213684 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0211944 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | 0.0211558 |
| EZR | ezrin | 0.0211282 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0211105 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.021026 |
| FKBP5 | FK506 binding protein 5 | 0.0205286 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0204152 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0200739 |
| ASPH | aspartate beta-hydroxylase | 0.0200026 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0199704 |
| PRKD1 | protein kinase D1 | 0.0199667 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0198863 |
| MGLL | monoglyceride lipase | 0.0197982 |
| SVIL | supervillin | 0.0197681 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.019764 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0196746 |
| EXOC4 | exocyst complex component 4 | 0.0195518 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.019531 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.0191633 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0191118 |
| TRIM56 | tripartite motif containing 56 | 0.0189664 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0189463 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.0189383 |
| RBM27 | RNA binding motif protein 27 | 0.0188115 |
| NPLOC4 | nuclear protein localization 4 homolog (S. cerevisiae) | 0.0188094 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0186568 |
| LDHA | lactate dehydrogenase A | 0.0186009 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0185414 |
| TMEM41B | transmembrane protein 41B | 0.0182803 |
| R3HDM2 | R3H domain containing 2 | 0.018032 |
| JUN | jun proto-oncogene | 0.0180096 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0179475 |
| NPTN | neuroplastin | 0.0178559 |
| EFNA5 | ephrin-A5 | 0.0174832 |
| ATRN | attractin | 0.0174212 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.017303 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.017294 |
| PATJ | PATJ crumbs cell polarity complex component | 0.017235 |
| TMEM245 | transmembrane protein 245 | 0.0172175 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0171014 |
| MYO1B | myosin IB | 0.0168762 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0168702 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 | 0.0168511 |
| PCBP3 | poly(rC) binding protein 3 | 0.0168046 |
| COPA | coatomer protein complex, subunit alpha | 0.0167709 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.016743 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.0166501 |
| TSPAN5 | tetraspanin 5 | 0.0165731 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0165089 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0164882 |
| ZBTB16 | zinc finger and BTB domain containing 16 | 0.016355 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0162926 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0161855 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0161701 |
| PROS1 | protein S (alpha) | 0.016134 |
| EGFR | epidermal growth factor receptor | 0.015994 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | -0.110161 |
| VIM | vimentin | -0.0931065 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0872231 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0712822 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0688107 |
| GOLGA4 | golgin A4 | -0.0628855 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0591324 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.054985 |
| TMSB10 | thymosin beta 10 | -0.054128 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0496955 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0490257 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0477265 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0453864 |
| RAD51B | RAD51 paralog B | -0.0422513 |
| NKTR | natural killer cell triggering receptor | -0.0399807 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0395538 |
| FMNL2 | formin-like 2 | -0.0390539 |
| FLNB | filamin B, beta | -0.0363279 |
| SMYD3 | SET and MYND domain containing 3 | -0.0363247 |
| DNER | delta/notch-like EGF repeat containing | -0.0360696 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0352661 |
| YAP1 | Yes-associated protein 1 | -0.0340396 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0331891 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0322715 |
| FNIP1 | folliculin interacting protein 1 | -0.0317674 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0313558 |
| RIN2 | Ras and Rab interactor 2 | -0.0308048 |
| TPX2 | TPX2, microtubule-associated | -0.0304044 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0301237 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0298977 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0286132 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0285661 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0283118 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0282322 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0278832 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0276843 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0276343 |
| RPL23 | ribosomal protein L23 | -0.0275902 |
| PKM | pyruvate kinase, muscle | -0.0275275 |
| RPL12 | ribosomal protein L12 | -0.027145 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0270403 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0267947 |
| PTMA | prothymosin, alpha | -0.0267476 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0267218 |
| SS18 | synovial sarcoma translocation, chromosome 18 | -0.0266587 |
| ATXN2 | ataxin 2 | -0.0265484 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | -0.0265232 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0264375 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0264315 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0262968 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0260488 |
| PCED1B | PC-esterase domain containing 1B | -0.0258312 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0255805 |
| DTNA | dystrobrevin, alpha | -0.0248962 |
| LAMA5 | laminin, alpha 5 | -0.0243173 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0242853 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | -0.0241703 |
| ANLN | anillin, actin binding protein | -0.024105 |
| SETD5 | SET domain containing 5 | -0.0239844 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0239586 |
| PCBP2 | poly(rC) binding protein 2 | -0.0238999 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0236745 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0232349 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.023053 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | -0.0229669 |
| NDRG1 | N-myc downstream regulated 1 | -0.0228814 |
| COL5A1 | collagen, type V, alpha 1 | -0.0227448 |
| KIF5B | kinesin family member 5B | -0.0227205 |
| RDX | radixin | -0.0225731 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0224832 |
| FAF2 | Fas associated factor family member 2 | -0.0224698 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0224318 |
| CDK19 | cyclin-dependent kinase 19 | -0.0223673 |
| POTEF | POTE ankyrin domain family, member F | -0.0223336 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.022308 |
| KDM5A | lysine (K)-specific demethylase 5A | -0.0222795 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0220687 |
| CENPF | centromere protein F, 350/400kDa | -0.0220484 |
| SEPTIN2 | septin 2 | -0.0220063 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0217738 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0216739 |
| TRIM44 | tripartite motif containing 44 | -0.0215325 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0213955 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0212852 |
| ZBTB1 | zinc finger and BTB domain containing 1 | -0.0209892 |
| MATR3 | matrin 3 | -0.020639 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0205549 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0204958 |
| MEF2A | myocyte enhancer factor 2A | -0.0204304 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0203982 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0203424 |
| EPC1 | enhancer of polycomb homolog 1 (Drosophila) | -0.0203359 |
| HDAC9 | histone deacetylase 9 | -0.0202352 |
| SCFD1 | sec1 family domain containing 1 | -0.0202264 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0201496 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.020075 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0199834 |
| ANKRD17 | ankyrin repeat domain 17 | -0.019879 |
| H3-3B | H3.3 histone B | -0.0198016 |
| SDC4 | syndecan 4 | -0.0197696 |
