| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bimatoprost perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bimatoprost_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0524165 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0451107 |
| NDRG1 | N-myc downstream regulated 1 | 0.0442769 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0433031 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0400412 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0374133 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0368234 |
| FAM13A | family with sequence similarity 13, member A | 0.0358562 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.03567 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0354581 |
| ASPH | aspartate beta-hydroxylase | 0.034937 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.034398 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0328854 |
| RPS12 | ribosomal protein S12 | 0.031944 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0308723 |
| MCL1 | myeloid cell leukemia 1 | 0.0304777 |
| PRELID2 | PRELI domain containing 2 | 0.030177 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0289644 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0286511 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0274351 |
| INTS6 | integrator complex subunit 6 | 0.0271536 |
| EFNA5 | ephrin-A5 | 0.0270548 |
| EGFR | epidermal growth factor receptor | 0.0270477 |
| MYOF | myoferlin | 0.0269006 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0267974 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0267505 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0260891 |
| ENO1 | enolase 1, (alpha) | 0.0260848 |
| IRS2 | insulin receptor substrate 2 | 0.0250011 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0240259 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0236762 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0234694 |
| ANGPTL4 | angiopoietin-like 4 | 0.0232388 |
| FAT1 | FAT atypical cadherin 1 | 0.0226935 |
| FLNB | filamin B, beta | 0.0221378 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0220296 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0220287 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0218086 |
| STC1 | stanniocalcin 1 | 0.0216609 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0214666 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0214623 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0213652 |
| EZR | ezrin | 0.0212206 |
| FAM107B | family with sequence similarity 107, member B | 0.0210939 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.020679 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0202268 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0196448 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0194107 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0192763 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0192356 |
| FMNL2 | formin-like 2 | 0.019215 |
| DUSP6 | dual specificity phosphatase 6 | 0.019135 |
| NEBL | nebulette | 0.0190909 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0184357 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0182758 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0181104 |
| SVIL | supervillin | 0.0177538 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0176545 |
| PTK2 | protein tyrosine kinase 2 | 0.0176455 |
| SIRT1 | sirtuin 1 | 0.0174602 |
| PDE10A | phosphodiesterase 10A | 0.0173777 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0172242 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0171353 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0170027 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.016871 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.016694 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.016693 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0166354 |
| ZNF638 | zinc finger protein 638 | 0.0166051 |
| FKBP5 | FK506 binding protein 5 | 0.01659 |
| PLIN2 | perilipin 2 | 0.0162382 |
| AHNAK | AHNAK nucleoprotein | 0.0161517 |
| DSPP | dentin sialophosphoprotein | 0.0160187 |
| APP | amyloid beta (A4) precursor protein | 0.0155764 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0155026 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0153455 |
| RPS4X | ribosomal protein S4, X-linked | 0.0153436 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0152494 |
| RPL9 | ribosomal protein L9 | 0.0151003 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0149193 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0148986 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0148877 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0148812 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0148708 |
| LAMB3 | laminin, beta 3 | 0.0148424 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0146669 |
| RPL36A | ribosomal protein L36a | 0.0145337 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0143745 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0142647 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0141625 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0141491 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0141333 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0140103 |
| TMF1 | TATA element modulatory factor 1 | 0.0139779 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.013799 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0137824 |
| ANXA1 | annexin A1 | 0.0135838 |
| MSN | moesin | 0.0134955 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0134843 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0134257 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.473355 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.324209 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.234846 |
| FN1 | fibronectin 1 | -0.200912 |
| NRG1 | neuregulin 1 | -0.115538 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.104185 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0904584 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.082008 |
| SQSTM1 | sequestosome 1 | -0.0789027 |
| SYT1 | synaptotagmin I | -0.078017 |
| HLA-B | major histocompatibility complex, class I, B | -0.071938 |
| ITGA1 | integrin, alpha 1 | -0.0656241 |
| TMSB10 | thymosin beta 10 | -0.0643096 |
| MAP1B | microtubule-associated protein 1B | -0.0590034 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0577503 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0574407 |
| FTL | ferritin, light polypeptide | -0.0540227 |
| PKM | pyruvate kinase, muscle | -0.0537778 |
| CENPF | centromere protein F, 350/400kDa | -0.0524156 |
| NRP1 | neuropilin 1 | -0.0503161 |
| GLIS3 | GLIS family zinc finger 3 | -0.0491516 |
| S100A6 | S100 calcium binding protein A6 | -0.0472681 |
| TMEM156 | transmembrane protein 156 | -0.0459946 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0457403 |
| VCL | vinculin | -0.0453403 |
| OSMR | oncostatin M receptor | -0.0451624 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0433327 |
| KLHL5 | kelch-like family member 5 | -0.0427231 |
| ETV1 | ets variant 1 | -0.0424719 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0398813 |
| TMEM165 | transmembrane protein 165 | -0.0395572 |
| MKI67 | marker of proliferation Ki-67 | -0.0392618 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0383729 |
| FNBP1 | formin binding protein 1 | -0.038193 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0381573 |
| EGR1 | early growth response 1 | -0.0378821 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0377646 |
| NTN4 | netrin 4 | -0.0363553 |
| HMGA2 | high mobility group AT-hook 2 | -0.0352015 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0348404 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0348168 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0338499 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0337816 |
| SMOX | spermine oxidase | -0.03286 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0327433 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0307147 |
| CALU | calumenin | -0.0302599 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0302093 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0296602 |
| TXNIP | thioredoxin interacting protein | -0.0296429 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0290253 |
| HMGA1 | high mobility group AT-hook 1 | -0.0288182 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0283156 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0279119 |
| RTN4 | reticulon 4 | -0.027621 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0271264 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0271089 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0269257 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0264381 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0261301 |
| FAF2 | Fas associated factor family member 2 | -0.0254927 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0254236 |
| LRP5 | low density lipoprotein receptor-related protein 5 | -0.0253753 |
| RRBP1 | ribosome binding protein 1 | -0.0251975 |
| ACTN4 | actinin, alpha 4 | -0.0251935 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0250846 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0250302 |
| KRT81 | keratin 81, type II | -0.0249589 |
| HLA-A | major histocompatibility complex, class I, A | -0.0248829 |
| SYNJ2 | synaptojanin 2 | -0.0245401 |
| SSH1 | slingshot protein phosphatase 1 | -0.0244172 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0242943 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0241928 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0238981 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0237319 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0234137 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0233188 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0232753 |
| TMEM263 | transmembrane protein 263 | -0.0230507 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0229098 |
| TXNRD1 | thioredoxin reductase 1 | -0.022893 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0225642 |
| TMEM131 | transmembrane protein 131 | -0.022509 |
| RAB31 | RAB31, member RAS oncogene family | -0.022505 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0223971 |
| RPS21 | ribosomal protein S21 | -0.0223703 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0223698 |
| ETNK1 | ethanolamine kinase 1 | -0.0222914 |
| ZNF644 | zinc finger protein 644 | -0.0221175 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0219681 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0218558 |
| TPI1 | triosephosphate isomerase 1 | -0.0218154 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0214951 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0213498 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0210891 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.021083 |
| FAM20C | family with sequence similarity 20, member C | -0.0210644 |
| ATN1 | atrophin 1 | -0.0210612 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0210583 |
| UBXN4 | UBX domain protein 4 | -0.0209036 |
