| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bimiralisib perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bimiralisib_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.197631 |
| LCN2 | lipocalin 2 | 0.150451 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.143404 |
| EXT1 | exostosin glycosyltransferase 1 | 0.11834 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.114187 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.103009 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0872563 |
| DST | dystonin | 0.082925 |
| RNF213 | ring finger protein 213 | 0.0827144 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0762272 |
| PHF3 | PHD finger protein 3 | 0.0735371 |
| INTS6 | integrator complex subunit 6 | 0.0730112 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.071634 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0704646 |
| PLSCR2 | phospholipid scramblase 2 | 0.0697738 |
| VMP1 | vacuole membrane protein 1 | 0.0696498 |
| FTL | ferritin, light polypeptide | 0.0694359 |
| SP100 | SP100 nuclear antigen | 0.0675814 |
| VCL | vinculin | 0.0674179 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0672113 |
| MYO1E | myosin IE | 0.0665545 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0655289 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0654013 |
| KYNU | kynureninase | 0.0652271 |
| SMAD3 | SMAD family member 3 | 0.0642465 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0616534 |
| SERINC5 | serine incorporator 5 | 0.0615355 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0590529 |
| ETV6 | ets variant 6 | 0.0588765 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0585851 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0579744 |
| PDZD8 | PDZ domain containing 8 | 0.0577569 |
| MX2 | MX dynamin-like GTPase 2 | 0.0569025 |
| MCU | mitochondrial calcium uniporter | 0.0566457 |
| TMC5 | transmembrane channel-like 5 | 0.0562663 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0556737 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0548927 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0528318 |
| HKDC1 | hexokinase domain containing 1 | 0.0517 |
| TJP1 | tight junction protein 1 | 0.0514586 |
| ZNF292 | zinc finger protein 292 | 0.0508544 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.050587 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0491255 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0457551 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0449169 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0435793 |
| FNIP2 | folliculin interacting protein 2 | 0.0419658 |
| MAP7 | microtubule-associated protein 7 | 0.0394965 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0387533 |
| SIK3 | SIK family kinase 3 | 0.038497 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0379948 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0379934 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.036508 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.035861 |
| RND3 | Rho family GTPase 3 | 0.0356484 |
| RBM47 | RNA binding motif protein 47 | 0.0354731 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0350114 |
| TOX3 | TOX high mobility group box family member 3 | 0.0347737 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0346613 |
| TMEM65 | transmembrane protein 65 | 0.0342551 |
| DPP4 | dipeptidyl-peptidase 4 | 0.0340503 |
| MX1 | MX dynamin-like GTPase 1 | 0.0338754 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0337052 |
| MYO5B | myosin VB | 0.0331986 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0329009 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0325084 |
| UBAP2 | ubiquitin associated protein 2 | 0.0316353 |
| RPS6 | ribosomal protein S6 | 0.0314883 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0314048 |
| BCL2L1 | BCL2-like 1 | 0.0312332 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0308688 |
| CLOCK | clock circadian regulator | 0.0304679 |
| EFNA5 | ephrin-A5 | 0.0301783 |
| LIMA1 | LIM domain and actin binding 1 | 0.0296975 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0288168 |
| XAF1 | XIAP associated factor 1 | 0.0286447 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.0282082 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0279874 |
| SYT1 | synaptotagmin I | 0.0278332 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0277241 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.027704 |
| DIAPH1 | diaphanous-related formin 1 | 0.027658 |
| TRIM2 | tripartite motif containing 2 | 0.0275594 |
| YAP1 | Yes-associated protein 1 | 0.0275418 |
| JAK1 | Janus kinase 1 | 0.0272239 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0267932 |
| WWOX | WW domain containing oxidoreductase | 0.0266857 |
| RPS12 | ribosomal protein S12 | 0.0263511 |
| AREG | amphiregulin | 0.0261655 |
| POF1B | premature ovarian failure, 1B | 0.0260706 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | 0.0258479 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0256568 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0254589 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0254226 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.025383 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0253399 |
| GK | glycerol kinase | 0.0252897 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0249432 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0247554 |
| NABP1 | nucleic acid binding protein 1 | 0.0247099 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.166607 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.115292 |
| EGR1 | early growth response 1 | -0.0910601 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0902795 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0870783 |
| NDRG1 | N-myc downstream regulated 1 | -0.0850157 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0832765 |
| ITGA6 | integrin, alpha 6 | -0.0808322 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0778723 |
| EZR | ezrin | -0.0690973 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0679578 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0647793 |
| H1-0 | H1.0 linker histone | -0.0643943 |
| CCNL1 | cyclin L1 | -0.0630426 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0586553 |
| PTMA | prothymosin, alpha | -0.0571472 |
| UBC | ubiquitin C | -0.056193 |
| RUNX1 | runt-related transcription factor 1 | -0.0559157 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.054213 |
| PTEN | phosphatase and tensin homolog | -0.0541562 |
| LYZ | lysozyme | -0.0517827 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0513807 |
| DIAPH3 | diaphanous-related formin 3 | -0.0509892 |
| RNF149 | ring finger protein 149 | -0.0504947 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0488683 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0479873 |
| PRKCA | protein kinase C, alpha | -0.0477477 |
| STK39 | serine threonine kinase 39 | -0.0476416 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.0465972 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0445539 |
| LDLR | low density lipoprotein receptor | -0.0442963 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0437284 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.043263 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0430469 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0424268 |
| GRK3 | G protein-coupled receptor kinase 3 | -0.0423004 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0412875 |
| WDR45B | WD repeat domain 45B | -0.0411457 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0404257 |
| NPSR1 | neuropeptide S receptor 1 | -0.0402163 |
| CANX | calnexin | -0.0401207 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.0399371 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0398853 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0396749 |
| CALR | calreticulin | -0.0392259 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.0387991 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.038709 |
| MKI67 | marker of proliferation Ki-67 | -0.0386545 |
| PKM | pyruvate kinase, muscle | -0.0385508 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.0383053 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0379315 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0379285 |
| HLA-B | major histocompatibility complex, class I, B | -0.0375169 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0372538 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0367283 |
| IRF1 | interferon regulatory factor 1 | -0.0359835 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0351548 |
| RBM39 | RNA binding motif protein 39 | -0.0350221 |
| AHNAK | AHNAK nucleoprotein | -0.0349853 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0349849 |
| RNF43 | ring finger protein 43 | -0.034927 |
| CMIP | c-Maf inducing protein | -0.0348052 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0346591 |
| PRELID2 | PRELI domain containing 2 | -0.0346219 |
| HDAC4 | histone deacetylase 4 | -0.0345087 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0343767 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0336824 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0336689 |
| SCARB1 | scavenger receptor class B, member 1 | -0.0331232 |
| ABHD2 | abhydrolase domain containing 2 | -0.0330259 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0328541 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0327817 |
| CALU | calumenin | -0.0324924 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0320391 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0317707 |
| TXNIP | thioredoxin interacting protein | -0.0316609 |
| HDLBP | high density lipoprotein binding protein | -0.0311168 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0302555 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0302234 |
| JUN | jun proto-oncogene | -0.0297537 |
| BRCA2 | breast cancer 2, early onset | -0.0296964 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0294499 |
| SPATA13 | spermatogenesis associated 13 | -0.0293716 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0292262 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.029044 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0289519 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0288365 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0283737 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0281765 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0280588 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0279578 |
| TMEM263 | transmembrane protein 263 | -0.0278464 |
| COPA | coatomer protein complex, subunit alpha | -0.0278299 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.027713 |
| SDCBP2 | syndecan binding protein (syntenin) 2 | -0.027527 |
| ZNRF3 | zinc and ring finger 3 | -0.0274606 |
| NCKAP5 | NCK-associated protein 5 | -0.027321 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0272935 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0271028 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0268833 |
