| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bimiralisib perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bimiralisib_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.130902 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | 0.0824418 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0768061 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0702571 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.058598 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0561355 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0531922 |
| SP100 | SP100 nuclear antigen | 0.048656 |
| SQSTM1 | sequestosome 1 | 0.0457959 |
| B2M | beta-2-microglobulin | 0.0447028 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0440348 |
| PALLD | palladin, cytoskeletal associated protein | 0.0408437 |
| PDLIM5 | PDZ and LIM domain 5 | 0.040533 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0401205 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0398237 |
| IFI44L | interferon-induced protein 44-like | 0.0397555 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0376296 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0367752 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0366324 |
| HLA-E | major histocompatibility complex, class I, E | 0.0362333 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0358487 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0354432 |
| ACTG1 | actin gamma 1 | 0.0352981 |
| RPS8 | ribosomal protein S8 | 0.0348649 |
| GOLGB1 | golgin B1 | 0.0344515 |
| RND3 | Rho family GTPase 3 | 0.0340474 |
| MX2 | MX dynamin-like GTPase 2 | 0.0339594 |
| RPS12 | ribosomal protein S12 | 0.0336245 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0335226 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0332414 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0320163 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0311595 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.030687 |
| VCL | vinculin | 0.0306668 |
| CFB | complement factor B | 0.0301877 |
| PLSCR1 | phospholipid scramblase 1 | 0.0300084 |
| MT2A | metallothionein 2A | 0.0295172 |
| RPS3 | ribosomal protein S3 | 0.0287118 |
| RIGI | RNA sensor RIG-I | 0.0286142 |
| ENO1 | enolase 1, (alpha) | 0.0274925 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0264033 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0262574 |
| VIM | vimentin | 0.025481 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.024968 |
| FBXO32 | F-box protein 32 | 0.0247336 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0246644 |
| RPS2 | ribosomal protein S2 | 0.0246108 |
| DSTN | destrin (actin depolymerizing factor) | 0.0232531 |
| MYADM | myeloid-associated differentiation marker | 0.0230229 |
| OPTN | optineurin | 0.0223757 |
| NEK10 | NIMA-related kinase 10 | 0.0220254 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0218371 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0216407 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0209158 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0207253 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0203699 |
| HLA-B | major histocompatibility complex, class I, B | 0.020309 |
| GBP1 | guanylate binding protein 1, interferon-inducible | 0.0202553 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0201695 |
| HDAC9 | histone deacetylase 9 | 0.0198351 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0198108 |
| RPS6 | ribosomal protein S6 | 0.0196638 |
| RPS25 | ribosomal protein S25 | 0.0195343 |
| VMP1 | vacuole membrane protein 1 | 0.0192811 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | 0.0191678 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.019121 |
| AEBP2 | AE binding protein 2 | 0.0190157 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0187623 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.0185121 |
| TPM4 | tropomyosin 4 | 0.0184749 |
| XAF1 | XIAP associated factor 1 | 0.0182162 |
| RACK1 | receptor for activated C kinase 1 | 0.0182032 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0181516 |
| LIMA1 | LIM domain and actin binding 1 | 0.0180073 |
| LDHA | lactate dehydrogenase A | 0.0179405 |
| FOXP1 | forkhead box P1 | 0.0177245 |
| RPL37A | ribosomal protein L37a | 0.0175723 |
| BRD2 | bromodomain containing 2 | 0.0174892 |
| DTX3L | deltex 3 like, E3 ubiquitin ligase | 0.0171826 |
| DST | dystonin | 0.0169345 |
| RPL26 | ribosomal protein L26 | 0.0164863 |
| COL3A1 | collagen, type III, alpha 1 | 0.0163707 |
| RPS23 | ribosomal protein S23 | 0.0163695 |
| RPL36 | ribosomal protein L36 | 0.0163437 |
| MX1 | MX dynamin-like GTPase 1 | 0.016307 |
| PLSCR2 | phospholipid scramblase 2 | 0.0161848 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 | 0.0161784 |
| BPTF | bromodomain PHD finger transcription factor | 0.0161235 |
| PMP22 | peripheral myelin protein 22 | 0.0161189 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0159528 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0157434 |
| CALD1 | caldesmon 1 | 0.0157015 |
| TLE4 | transducin-like enhancer of split 4 | 0.0156478 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0156244 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0155988 |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta | 0.0154205 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0153543 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | 0.0153105 |
| RPL11 | ribosomal protein L11 | 0.0152758 |
| NEK11 | NIMA-related kinase 11 | 0.0151164 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | -0.277799 |
| NDRG1 | N-myc downstream regulated 1 | -0.238357 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.221081 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.196069 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.174006 |
| CDH13 | cadherin 13 | -0.127866 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.12112 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.115546 |
| COL1A1 | collagen, type I, alpha 1 | -0.11276 |
| PDE10A | phosphodiesterase 10A | -0.104057 |
| ATP13A3 | ATPase type 13A3 | -0.0787229 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.076262 |
| CADM1 | cell adhesion molecule 1 | -0.0723952 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0659599 |
| COL5A1 | collagen, type V, alpha 1 | -0.0655442 |
| TMSB10 | thymosin beta 10 | -0.063057 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0607294 |
| LOXL2 | lysyl oxidase-like 2 | -0.0591679 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0567732 |
| ASPH | aspartate beta-hydroxylase | -0.0561531 |
| COL1A2 | collagen, type I, alpha 2 | -0.053104 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.052639 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0512221 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0500236 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0486921 |
| STC1 | stanniocalcin 1 | -0.0477426 |
| HMGA2 | high mobility group AT-hook 2 | -0.0468578 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0437001 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0433779 |
| LOX | lysyl oxidase | -0.0427173 |
| CALR | calreticulin | -0.0419219 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.041724 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0406632 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0405278 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0401102 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0392257 |
| EGR1 | early growth response 1 | -0.0384928 |
| ZNF292 | zinc finger protein 292 | -0.0367913 |
| SPAG9 | sperm associated antigen 9 | -0.0366185 |
| MTSS1 | metastasis suppressor 1 | -0.0362481 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0361035 |
| PTMA | prothymosin, alpha | -0.0355971 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0353609 |
| FN1 | fibronectin 1 | -0.0348861 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0341778 |
| IER3 | immediate early response 3 | -0.0339923 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0337762 |
| CANX | calnexin | -0.0336144 |
| USP3 | ubiquitin specific peptidase 3 | -0.032702 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0326968 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0325382 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0324918 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | -0.0316537 |
| EFNA5 | ephrin-A5 | -0.0315551 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0313276 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0313138 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0310202 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0309918 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.030875 |
| RTN4 | reticulon 4 | -0.0306981 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0306644 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0303792 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0302805 |
| FMNL2 | formin-like 2 | -0.0302763 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0302002 |
| RLF | rearranged L-myc fusion | -0.0301534 |
| GOLGA4 | golgin A4 | -0.0298979 |
| CLINT1 | clathrin interactor 1 | -0.0298063 |
| DOCK5 | dedicator of cytokinesis 5 | -0.02979 |
| CALU | calumenin | -0.0296745 |
| MYO10 | myosin X | -0.0296177 |
| VCAN | versican | -0.0294407 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0293885 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0293127 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0290917 |
| COG5 | component of oligomeric golgi complex 5 | -0.0290546 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0289154 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.02891 |
| PTK2 | protein tyrosine kinase 2 | -0.028867 |
| RUNX1 | runt-related transcription factor 1 | -0.0287092 |
| ECE1 | endothelin converting enzyme 1 | -0.0285603 |
| TMEM165 | transmembrane protein 165 | -0.0284111 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0282013 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0277866 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0276264 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0275074 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0272187 |
| RRBP1 | ribosome binding protein 1 | -0.0272031 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0271778 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0266977 |
| SEC24A | SEC24 family member A | -0.0265691 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0263435 |
| CABIN1 | calcineurin binding protein 1 | -0.0262314 |
| TFG | TRK-fused gene | -0.0261308 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0260931 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0258029 |
| COPA | coatomer protein complex, subunit alpha | -0.0257233 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0252628 |
| QKI | QKI, KH domain containing, RNA binding | -0.0251463 |
| RBM39 | RNA binding motif protein 39 | -0.0250667 |
