| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bimiralisib perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bimiralisib_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.201204 |
| CLU | clusterin | 0.122969 |
| LMO7 | LIM domain 7 | 0.0934984 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0650603 |
| B2M | beta-2-microglobulin | 0.0591789 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0566818 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0560583 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0538376 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0519826 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0492794 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0491099 |
| IFI44L | interferon-induced protein 44-like | 0.0456676 |
| RPS8 | ribosomal protein S8 | 0.0453994 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0452319 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0452119 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0448622 |
| RAI14 | retinoic acid induced 14 | 0.0447688 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.044159 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0440779 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.0440557 |
| TXNIP | thioredoxin interacting protein | 0.0438592 |
| MT2A | metallothionein 2A | 0.043782 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0425301 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0423235 |
| HLA-E | major histocompatibility complex, class I, E | 0.0420362 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0406073 |
| SQSTM1 | sequestosome 1 | 0.038839 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0363043 |
| SP100 | SP100 nuclear antigen | 0.0355567 |
| ITGB8 | integrin, beta 8 | 0.0350067 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0344218 |
| MT1E | metallothionein 1E | 0.0324253 |
| AOPEP | aminopeptidase O (putative) | 0.0320038 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0309601 |
| RPS6 | ribosomal protein S6 | 0.0308963 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0304404 |
| HLA-B | major histocompatibility complex, class I, B | 0.0297507 |
| RPS12 | ribosomal protein S12 | 0.0294269 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0293587 |
| DOK5 | docking protein 5 | 0.0286182 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0273755 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0267365 |
| FTL | ferritin, light polypeptide | 0.0267168 |
| KYNU | kynureninase | 0.0263829 |
| RPS25 | ribosomal protein S25 | 0.0262084 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0254559 |
| EGFR | epidermal growth factor receptor | 0.0253658 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0250581 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0241252 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.023889 |
| CLDN1 | claudin 1 | 0.0237656 |
| RAD51B | RAD51 paralog B | 0.0235226 |
| MX1 | MX dynamin-like GTPase 1 | 0.0234765 |
| RPL37 | ribosomal protein L37 | 0.0234534 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 0.0231566 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0230024 |
| RIGI | RNA sensor RIG-I | 0.023002 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0229862 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0229722 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.022942 |
| RPLP2 | ribosomal protein, large, P2 | 0.0229084 |
| DSPP | dentin sialophosphoprotein | 0.0227104 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0223123 |
| RPLP1 | ribosomal protein, large, P1 | 0.0221713 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0220982 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.021905 |
| TRIM56 | tripartite motif containing 56 | 0.0215473 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.0212843 |
| RPL31 | ribosomal protein L31 | 0.0208298 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0207694 |
| MEIS2 | Meis homeobox 2 | 0.0206828 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0204748 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0204662 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0203556 |
| GBP4 | guanylate binding protein 4 | 0.0203456 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0199159 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.0198949 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0194728 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.0194692 |
| CNTNAP3 | contactin associated protein-like 3 | 0.019405 |
| EXOC4 | exocyst complex component 4 | 0.0193923 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0191054 |
| PHF3 | PHD finger protein 3 | 0.0190714 |
| RPL34 | ribosomal protein L34 | 0.0190116 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0189541 |
| RPL23 | ribosomal protein L23 | 0.0189238 |
| PLPP1 | phospholipid phosphatase 1 | 0.0188751 |
| TNRC6B | trinucleotide repeat containing 6B | 0.018806 |
| RPS27 | ribosomal protein S27 | 0.0186799 |
| XAF1 | XIAP associated factor 1 | 0.0184301 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0181645 |
| AHNAK | AHNAK nucleoprotein | 0.0179062 |
| RPS14 | ribosomal protein S14 | 0.0178334 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0176328 |
| RPL5 | ribosomal protein L5 | 0.0176258 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0175949 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0175267 |
| RPS19 | ribosomal protein S19 | 0.0174603 |
| TMOD3 | tropomodulin 3 (ubiquitous) | 0.0174406 |
| RPS13 | ribosomal protein S13 | 0.0174138 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | -0.308756 |
| NDRG1 | N-myc downstream regulated 1 | -0.14738 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.111443 |
| ITGA6 | integrin, alpha 6 | -0.100402 |
| STC1 | stanniocalcin 1 | -0.069636 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0694994 |
| BCL2L1 | BCL2-like 1 | -0.0675287 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0667362 |
| EMP1 | epithelial membrane protein 1 | -0.0655435 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0629185 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.061138 |
| FOXO1 | forkhead box O1 | -0.0603166 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0598477 |
| MYO10 | myosin X | -0.0596311 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.058726 |
| PODXL | podocalyxin-like | -0.0526722 |
| SULF1 | sulfatase 1 | -0.0517428 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0513908 |
| ANXA2 | annexin A2 | -0.0499313 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0476082 |
| MSN | moesin | -0.0462743 |
| CUL4B | cullin 4B | -0.0457639 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.041543 |
| RBM39 | RNA binding motif protein 39 | -0.0414662 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.040542 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.040359 |
| MEF2A | myocyte enhancer factor 2A | -0.0402807 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0395233 |
| CAPRIN2 | caprin family member 2 | -0.0394946 |
| ASPH | aspartate beta-hydroxylase | -0.0390112 |
| RIN2 | Ras and Rab interactor 2 | -0.0389936 |
| GOLGA4 | golgin A4 | -0.0387344 |
| FOSL1 | FOS-like antigen 1 | -0.0386613 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0383233 |
| EZR | ezrin | -0.0374778 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0368592 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0368515 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0367858 |
| DUSP6 | dual specificity phosphatase 6 | -0.0367228 |
| ANKRD33B | ankyrin repeat domain 33B | -0.03651 |
| CALU | calumenin | -0.0364117 |
| LMNA | lamin A/C | -0.0364057 |
| EPHA2 | EPH receptor A2 | -0.0363766 |
| LAMA5 | laminin, alpha 5 | -0.0356263 |
| ANLN | anillin, actin binding protein | -0.0356024 |
| PLEC | plectin | -0.035316 |
| COPA | coatomer protein complex, subunit alpha | -0.0350454 |
| EGR1 | early growth response 1 | -0.0344165 |
| SQLE | squalene epoxidase | -0.0342841 |
| EFHD2 | EF-hand domain family, member D2 | -0.0338808 |
| FLNA | filamin A, alpha | -0.033684 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0333933 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0331361 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0330767 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.0326182 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0324477 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0322084 |
| PKM | pyruvate kinase, muscle | -0.0321344 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0318037 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0312743 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0311297 |
| KRT6A | keratin 6A, type II | -0.0310958 |
| TPM3 | tropomyosin 3 | -0.0309241 |
| ACTN4 | actinin, alpha 4 | -0.030889 |
| PGK1 | phosphoglycerate kinase 1 | -0.0307992 |
| LUZP1 | leucine zipper protein 1 | -0.030246 |
| FN1 | fibronectin 1 | -0.0300287 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0298819 |
| SPAG9 | sperm associated antigen 9 | -0.0297504 |
| POTEF | POTE ankyrin domain family, member F | -0.0297141 |
| RTN4 | reticulon 4 | -0.0293777 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0289951 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0289248 |
| CDK6 | cyclin-dependent kinase 6 | -0.0288622 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0283141 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.0282477 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0281266 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0278873 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0275511 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0275177 |
| DUSP4 | dual specificity phosphatase 4 | -0.0274974 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0274792 |
| KIAA0040 | KIAA0040 | -0.0272112 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0268992 |
| SUCO | SUN domain containing ossification factor | -0.0267687 |
| AMOTL1 | angiomotin like 1 | -0.02666 |
| WASF2 | WAS protein family, member 2 | -0.0264399 |
| CMIP | c-Maf inducing protein | -0.0264144 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0263388 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0260765 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0260509 |
| C4BPB | complement component 4 binding protein, beta | -0.0258392 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.025824 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0254085 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0253142 |
| LDLR | low density lipoprotein receptor | -0.025229 |
| CD44 | CD44 molecule (Indian blood group) | -0.0251159 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | -0.0250528 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0248699 |
| ACER3 | alkaline ceramidase 3 | -0.0247121 |
