| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bimiralisib perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bimiralisib_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.16534 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.114303 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0792283 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.078983 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0718203 |
| FOXP1 | forkhead box P1 | 0.0709101 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0701724 |
| NPSR1 | neuropeptide S receptor 1 | 0.066794 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0659715 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0646378 |
| MYO1E | myosin IE | 0.0598494 |
| DSPP | dentin sialophosphoprotein | 0.0541801 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.05349 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0523683 |
| MUC13 | mucin 13, cell surface associated | 0.0521803 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0506896 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.0483994 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.047054 |
| PARD3B | par-3 family cell polarity regulator beta | 0.044318 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0409578 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0397268 |
| MECOM | MDS1 and EVI1 complex locus | 0.0392756 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0387105 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0386491 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0386307 |
| NEBL | nebulette | 0.0375337 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0372539 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.037039 |
| POF1B | premature ovarian failure, 1B | 0.0353667 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.0335581 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0335407 |
| FHIT | fragile histidine triad | 0.0329419 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0329333 |
| RAD51B | RAD51 paralog B | 0.0327706 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | 0.0323475 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0311643 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0310454 |
| PCDH9 | protocadherin 9 | 0.0310271 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0307972 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | 0.0304748 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0303394 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0299004 |
| RPS12 | ribosomal protein S12 | 0.0293002 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0290672 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0289334 |
| FOXP2 | forkhead box P2 | 0.0287499 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.0287025 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0273574 |
| SVIL | supervillin | 0.0268895 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0268031 |
| NRXN3 | neurexin 3 | 0.0264741 |
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | 0.0263005 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | 0.0261804 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0251288 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0248883 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0239491 |
| EXOC4 | exocyst complex component 4 | 0.0238425 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0237266 |
| ATXN1 | ataxin 1 | 0.0234978 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0232199 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0230262 |
| RPS8 | ribosomal protein S8 | 0.0226805 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0221899 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0221609 |
| ACTG1 | actin gamma 1 | 0.0220527 |
| DST | dystonin | 0.0219741 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0219189 |
| PALLD | palladin, cytoskeletal associated protein | 0.0210731 |
| MACROD2 | MACRO domain containing 2 | 0.021049 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0206743 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | 0.0206272 |
| CUX1 | cut-like homeobox 1 | 0.0205993 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0205841 |
| JUN | jun proto-oncogene | 0.0204376 |
| B2M | beta-2-microglobulin | 0.0200997 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0199372 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0199123 |
| PRSS23 | protease, serine, 23 | 0.0196212 |
| AEBP2 | AE binding protein 2 | 0.0195389 |
| DIAPH2 | diaphanous-related formin 2 | 0.0195234 |
| TMC5 | transmembrane channel-like 5 | 0.0192135 |
| TPM1 | tropomyosin 1 (alpha) | 0.0191629 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | 0.0191606 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0186326 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.018477 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.018265 |
| PHF3 | PHD finger protein 3 | 0.0182261 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0180524 |
| DSG2 | desmoglein 2 | 0.0177819 |
| WWOX | WW domain containing oxidoreductase | 0.0176187 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0175608 |
| EGFR | epidermal growth factor receptor | 0.0172072 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0170654 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0169749 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | 0.0169421 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0167094 |
| KIZ | kizuna centrosomal protein | 0.0166789 |
| NABP1 | nucleic acid binding protein 1 | 0.0166038 |
| KLF6 | Kruppel-like factor 6 | 0.0166025 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0165987 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.192441 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.138553 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.130374 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.129342 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.100889 |
| TNS4 | tensin 4 | -0.0958169 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0918156 |
| GOLGA4 | golgin A4 | -0.0871853 |
| ANXA2 | annexin A2 | -0.0841699 |
| NDRG1 | N-myc downstream regulated 1 | -0.0790002 |
| FLNB | filamin B, beta | -0.0708589 |
| FAT1 | FAT atypical cadherin 1 | -0.0679114 |
| RNF43 | ring finger protein 43 | -0.0667719 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0633776 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0630734 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0607629 |
| LDHA | lactate dehydrogenase A | -0.0587667 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0569486 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0568796 |
| RNF145 | ring finger protein 145 | -0.0545516 |
| GPHN | gephyrin | -0.053926 |
| TMSB10 | thymosin beta 10 | -0.0534762 |
| PKM | pyruvate kinase, muscle | -0.0534022 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0527409 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0526042 |
| FAM13A | family with sequence similarity 13, member A | -0.0498066 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0494612 |
| ITGA6 | integrin, alpha 6 | -0.049251 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0485389 |
| WDR45B | WD repeat domain 45B | -0.0460717 |
| MED13L | mediator complex subunit 13-like | -0.0459272 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.045865 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0452634 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0446066 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0445029 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0442577 |
| RBM39 | RNA binding motif protein 39 | -0.0442371 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0439997 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0436201 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0430928 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0420211 |
| ASPH | aspartate beta-hydroxylase | -0.0419883 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0417975 |
| S100P | S100 calcium binding protein P | -0.0407526 |
| GDF15 | growth differentiation factor 15 | -0.0404192 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0400553 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0397628 |
| OGA | O-GlcNAcase | -0.039407 |
| KIF5B | kinesin family member 5B | -0.0393234 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0387748 |
| COG5 | component of oligomeric golgi complex 5 | -0.0384622 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0381251 |
| SETD5 | SET domain containing 5 | -0.0377278 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0373676 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0372696 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0371338 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0368893 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0368098 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0359297 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0355205 |
| EREG | epiregulin | -0.0353794 |
| DSCAM | Down syndrome cell adhesion molecule | -0.034953 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0348209 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0346901 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0346478 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0337585 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.0335505 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0328023 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0327906 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0322872 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0320182 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0315903 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0315462 |
| HDLBP | high density lipoprotein binding protein | -0.0312534 |
| ITGB4 | integrin, beta 4 | -0.0312269 |
| RREB1 | ras responsive element binding protein 1 | -0.0311996 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0311593 |
| AREG | amphiregulin | -0.0310227 |
| ACTN4 | actinin, alpha 4 | -0.0309314 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0306989 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0305684 |
| PTMA | prothymosin, alpha | -0.0302012 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0300669 |
| TXNRD1 | thioredoxin reductase 1 | -0.0299034 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0296328 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0295885 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0295382 |
| H1-0 | H1.0 linker histone | -0.0295005 |
| MLEC | malectin | -0.0294549 |
| NFIA | nuclear factor I/A | -0.0293689 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0292378 |
| ONECUT3 | one cut homeobox 3 | -0.0292128 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0291148 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0289449 |
| TFG | TRK-fused gene | -0.0289387 |
| DERA | deoxyribose-phosphate aldolase (putative) | -0.0287728 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0286142 |
| KRT8 | keratin 8, type II | -0.0285441 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | -0.0284505 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0282885 |
