| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bimiralisib perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bimiralisib_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FOXP2 | forkhead box P2 | 0.0787184 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0756343 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0745877 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.0627949 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0627411 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0614183 |
| PUM1 | pumilio RNA-binding family member 1 | 0.059266 |
| ZNF292 | zinc finger protein 292 | 0.0536141 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0514537 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0504195 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.049539 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0469056 |
| PHF3 | PHD finger protein 3 | 0.0453502 |
| FN1 | fibronectin 1 | 0.0449453 |
| CDK13 | cyclin-dependent kinase 13 | 0.0438544 |
| TLK1 | tousled-like kinase 1 | 0.0436793 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0424721 |
| RPS2 | ribosomal protein S2 | 0.0412289 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0410792 |
| KIF5B | kinesin family member 5B | 0.0403184 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0391648 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0391142 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0390237 |
| RASAL2 | RAS protein activator like 2 | 0.0385202 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0384359 |
| HDAC9 | histone deacetylase 9 | 0.0383226 |
| ZNF608 | zinc finger protein 608 | 0.0369017 |
| SP3 | Sp3 transcription factor | 0.0368423 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0364513 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0358187 |
| RYBP | RING1 and YY1 binding protein | 0.0354078 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0350748 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0350604 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0342945 |
| ATXN2 | ataxin 2 | 0.0337588 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0336924 |
| NEK7 | NIMA-related kinase 7 | 0.0330286 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0327548 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0322655 |
| SMYD3 | SET and MYND domain containing 3 | 0.0318202 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0314692 |
| JMJD1C | jumonji domain containing 1C | 0.0313773 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0310571 |
| PCNX4 | pecanex 4 | 0.0301153 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0295788 |
| XPO1 | exportin 1 | 0.0293336 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.029332 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0293047 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | 0.0292062 |
| DENND4C | DENN/MADD domain containing 4C | 0.0291632 |
| RPS12 | ribosomal protein S12 | 0.0286299 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0280497 |
| GPC4 | glypican 4 | 0.0278059 |
| UBE3C | ubiquitin protein ligase E3C | 0.0275821 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0274245 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0272186 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0271451 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.026807 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0264718 |
| RPL21 | ribosomal protein L21 | 0.0264321 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0264123 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0258475 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.025645 |
| MB21D2 | Mab-21 domain containing 2 | 0.0255024 |
| FILIP1 | filamin A interacting protein 1 | 0.0254948 |
| OGA | O-GlcNAcase | 0.025443 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.025292 |
| SERTAD2 | SERTA domain containing 2 | 0.0252493 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.025183 |
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 | 0.0249909 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0246834 |
| PTK2 | protein tyrosine kinase 2 | 0.0246477 |
| USP3 | ubiquitin specific peptidase 3 | 0.0245011 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0243029 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0242865 |
| CDC73 | cell division cycle 73 | 0.0242298 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0240959 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0239029 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0237933 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0237352 |
| MEMO1 | mediator of cell motility 1 | 0.0236236 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0235292 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0234337 |
| MRTFA | myocardin related transcription factor A | 0.0233184 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | 0.023259 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0232331 |
| SPAG9 | sperm associated antigen 9 | 0.0231466 |
| PSPC1 | paraspeckle component 1 | 0.0231462 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0230115 |
| LATS2 | large tumor suppressor kinase 2 | 0.022876 |
| B3GALNT2 | beta-1,3-N-acetylgalactosaminyltransferase 2 | 0.02271 |
| DROSHA | drosha, ribonuclease type III | 0.0224392 |
| SBF2 | SET binding factor 2 | 0.0223921 |
| PTGES2 | prostaglandin E synthase 2 | 0.0222556 |
| TSC22D2 | TSC22 domain family, member 2 | 0.022162 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0221202 |
| H1-4 | H1.4 linker histone, cluster member | 0.0220285 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0220238 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0219988 |
| PDE7A | phosphodiesterase 7A | 0.0218321 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.176039 |
| VIM | vimentin | -0.145034 |
| ITGAV | integrin, alpha V | -0.0951875 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0897537 |
| THBS1 | thrombospondin 1 | -0.0866547 |
| TMSB10 | thymosin beta 10 | -0.0749371 |
| SYT1 | synaptotagmin I | -0.0733126 |
| PTMA | prothymosin, alpha | -0.0716327 |
| ACTG1 | actin gamma 1 | -0.0679193 |
| NRG1 | neuregulin 1 | -0.0652105 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0600896 |
| DST | dystonin | -0.0585897 |
| NCAM2 | neural cell adhesion molecule 2 | -0.056156 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0519627 |
| FAM171B | family with sequence similarity 171, member B | -0.0516773 |
| RPL35A | ribosomal protein L35a | -0.0515262 |
| POTEF | POTE ankyrin domain family, member F | -0.0506622 |
| ARHGAP15 | Rho GTPase activating protein 15 | -0.0483804 |
| TMSB4X | thymosin beta 4, X-linked | -0.0477544 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0475867 |
| COL5A2 | collagen, type V, alpha 2 | -0.0474402 |
| CENPF | centromere protein F, 350/400kDa | -0.0469871 |
| NPAS3 | neuronal PAS domain protein 3 | -0.046583 |
| SLC44A5 | solute carrier family 44, member 5 | -0.04617 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0448606 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0446804 |
| PGK1 | phosphoglycerate kinase 1 | -0.0446666 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0431096 |
| RPS24 | ribosomal protein S24 | -0.0430521 |
| PCDH7 | protocadherin 7 | -0.0430434 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0428116 |
| PFN1 | profilin 1 | -0.0425476 |
| RPLP1 | ribosomal protein, large, P1 | -0.0420341 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.041689 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.0399418 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.039784 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0394947 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0390007 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0388819 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0381794 |
| CAVIN1 | caveolae associated protein 1 | -0.0378311 |
| HMGB1 | high mobility group box 1 | -0.0372969 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.036907 |
| DMD | dystrophin | -0.0359978 |
| ACTN4 | actinin, alpha 4 | -0.0358296 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0358013 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0350991 |
| CALR | calreticulin | -0.0348698 |
| CCN2 | cellular communication network factor 2 | -0.0348269 |
| TXNRD1 | thioredoxin reductase 1 | -0.0346983 |
| YBX1 | Y box binding protein 1 | -0.0344678 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0342502 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | -0.0340392 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.033936 |
| PCDH9 | protocadherin 9 | -0.0332846 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.03315 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0328713 |
| ANXA1 | annexin A1 | -0.032798 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0325318 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0322175 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0320962 |
| GPC3 | glypican 3 | -0.0319405 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0314857 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0311428 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0311367 |
| PKM | pyruvate kinase, muscle | -0.0308112 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0304393 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0300838 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0299135 |
| SFRP4 | secreted frizzled-related protein 4 | -0.029771 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0296113 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0295401 |
| RIGI | RNA sensor RIG-I | -0.0293646 |
| SEPTIN7 | septin 7 | -0.0286062 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0285954 |
| TUT4 | terminal uridylyl transferase 4 | -0.0277708 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0277196 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0277126 |
| RPL37 | ribosomal protein L37 | -0.0276932 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0275002 |
| RPS13 | ribosomal protein S13 | -0.0274608 |
| CENPE | centromere protein E, 312kDa | -0.0273931 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0273704 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | -0.0273139 |
| LOC112694756 | uncharaterized LOC112694756 | -0.027262 |
| FOXP1 | forkhead box P1 | -0.0272588 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0271488 |
| RBM20 | RNA binding motif protein 20 | -0.0269523 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0268701 |
| EMP1 | epithelial membrane protein 1 | -0.0268619 |
| NELL2 | NEL-like 2 (chicken) | -0.0268562 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0265294 |
| COL1A2 | collagen, type I, alpha 2 | -0.026267 |
| RTN4 | reticulon 4 | -0.0261916 |
| SLC30A8 | solute carrier family 30 (zinc transporter), member 8 | -0.0261791 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0261399 |
| TPM1 | tropomyosin 1 (alpha) | -0.0261278 |
| MTCL1 | microtubule crosslinking factor 1 | -0.0259299 |
| AHNAK | AHNAK nucleoprotein | -0.025879 |
| CANX | calnexin | -0.025867 |
