| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bimiralisib perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bimiralisib_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.125282 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.123935 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.114822 |
| VCL | vinculin | 0.0978907 |
| PDGFC | platelet derived growth factor C | 0.0852707 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0736184 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0731777 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0688814 |
| EGFR | epidermal growth factor receptor | 0.0650532 |
| ZNF608 | zinc finger protein 608 | 0.06435 |
| HDAC9 | histone deacetylase 9 | 0.0640902 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0604941 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0586223 |
| EZR | ezrin | 0.0559309 |
| GLI3 | GLI family zinc finger 3 | 0.0540761 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0533827 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0532472 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0504664 |
| RPL26 | ribosomal protein L26 | 0.0492969 |
| PRELID2 | PRELI domain containing 2 | 0.0457873 |
| TJP1 | tight junction protein 1 | 0.0426109 |
| MYO5C | myosin VC | 0.0424195 |
| HSPB1 | heat shock 27kDa protein 1 | 0.0408157 |
| ANXA1 | annexin A1 | 0.040815 |
| RPS8 | ribosomal protein S8 | 0.0402345 |
| BMP2K | BMP2 inducible kinase | 0.0390827 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0384731 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0382092 |
| NBEA | neurobeachin | 0.0378835 |
| RPS2 | ribosomal protein S2 | 0.0364438 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0360406 |
| FOXP1 | forkhead box P1 | 0.0355791 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0340095 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0333577 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0332244 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0325666 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0311367 |
| RPL18 | ribosomal protein L18 | 0.0297837 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0295824 |
| H1-4 | H1.4 linker histone, cluster member | 0.0295364 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0289019 |
| RPL7 | ribosomal protein L7 | 0.0282208 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.027651 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0274113 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | 0.0271043 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0268792 |
| RPL12 | ribosomal protein L12 | 0.0268743 |
| PLK2 | polo-like kinase 2 | 0.0267772 |
| PYGB | phosphorylase, glycogen; brain | 0.026356 |
| TMCO3 | transmembrane and coiled-coil domains 3 | 0.0263193 |
| RIPOR2 | RHO family interacting cell polarization regulator 2 | 0.0260204 |
| AHNAK | AHNAK nucleoprotein | 0.0259964 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0259551 |
| RPS6 | ribosomal protein S6 | 0.0255 |
| TRIM24 | tripartite motif containing 24 | 0.0253238 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | 0.0251302 |
| NUP153 | nucleoporin 153kDa | 0.0249405 |
| CAVIN2 | caveolae associated protein 2 | 0.0248573 |
| RPS12 | ribosomal protein S12 | 0.0244115 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0243073 |
| TASOR2 | transcription activation suppressor family member 2 | 0.0240192 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0240028 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0238845 |
| ZNF638 | zinc finger protein 638 | 0.023761 |
| VMP1 | vacuole membrane protein 1 | 0.0234468 |
| DUSP4 | dual specificity phosphatase 4 | 0.0234049 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.0233272 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0230634 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0223715 |
| JMJD1C | jumonji domain containing 1C | 0.0223131 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0222945 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0222444 |
| GLI2 | GLI family zinc finger 2 | 0.0222118 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0221001 |
| ZNF217 | zinc finger protein 217 | 0.0216811 |
| TMEM65 | transmembrane protein 65 | 0.0214188 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0213421 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0212609 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.021188 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0210824 |
| RPLP2 | ribosomal protein, large, P2 | 0.0208692 |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 | 0.0206997 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.0205946 |
| RPL32 | ribosomal protein L32 | 0.0204529 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0203402 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0201391 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0200217 |
| FAM91A1 | family with sequence similarity 91, member A1 | 0.0198846 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0197756 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0197527 |
| MLIP | muscular LMNA-interacting protein | 0.0196654 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0195661 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0194542 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.019411 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0193932 |
| RPL21 | ribosomal protein L21 | 0.0193012 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0189629 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.0187686 |
| RACK1 | receptor for activated C kinase 1 | 0.0186448 |
| FER1L6 | fer-1-like family member 6 | 0.0186065 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.267856 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.118154 |
| PKM | pyruvate kinase, muscle | -0.100282 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0856992 |
| RPL35A | ribosomal protein L35a | -0.0836027 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0709751 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0702544 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0671851 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0622508 |
| RBM39 | RNA binding motif protein 39 | -0.0598897 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0571176 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0532535 |
| POTEF | POTE ankyrin domain family, member F | -0.0474718 |
| PFN1 | profilin 1 | -0.0474417 |
| S100A6 | S100 calcium binding protein A6 | -0.0463539 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0452347 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0437516 |
| FHIT | fragile histidine triad | -0.0425131 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0422509 |
| VIM | vimentin | -0.0419706 |
| RPL9 | ribosomal protein L9 | -0.0413691 |
| DIAPH3 | diaphanous-related formin 3 | -0.0413106 |
| WDR45B | WD repeat domain 45B | -0.0412881 |
| ACTG1 | actin gamma 1 | -0.0407769 |
| PRDX2 | peroxiredoxin 2 | -0.0406934 |
| TMSB10 | thymosin beta 10 | -0.039431 |
| FTL | ferritin, light polypeptide | -0.0386747 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0381011 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0380795 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0375594 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0370265 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0362506 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0361616 |
| MED13L | mediator complex subunit 13-like | -0.0351584 |
| TMSB4X | thymosin beta 4, X-linked | -0.0342636 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0335705 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0332554 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0329336 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0325878 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0324743 |
| NDRG1 | N-myc downstream regulated 1 | -0.0311624 |
| RPL13A | ribosomal protein L13a | -0.0311525 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0306671 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0305812 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0305161 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0301543 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0299673 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0298545 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0298146 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.029574 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0288535 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0288466 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0283895 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0283386 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0283141 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0282268 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0274496 |
| RPL27A | ribosomal protein L27a | -0.0274276 |
| HLA-B | major histocompatibility complex, class I, B | -0.0266079 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0265999 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0265846 |
| HLA-E | major histocompatibility complex, class I, E | -0.0265728 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0265447 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0262469 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0259842 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0257236 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0255642 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0255109 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0255091 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0254983 |
| SRP54 | signal recognition particle 54kDa | -0.0254522 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0249475 |
| SS18 | synovial sarcoma translocation, chromosome 18 | -0.0249435 |
| DARS1 | aspartyl-tRNA synthetase 1 | -0.0246793 |
| CCNL1 | cyclin L1 | -0.0243281 |
| GNAS | GNAS complex locus | -0.0242683 |
| GOLGA4 | golgin A4 | -0.0239899 |
| NF1 | neurofibromin 1 | -0.0239334 |
| PCBP2 | poly(rC) binding protein 2 | -0.0238254 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0237372 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0236484 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0236007 |
| EVI5 | ecotropic viral integration site 5 | -0.0235107 |
| MORF4L1 | mortality factor 4 like 1 | -0.0235102 |
| RPS19 | ribosomal protein S19 | -0.0233874 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0233835 |
| STAG2 | stromal antigen 2 | -0.0233152 |
| ZNF207 | zinc finger protein 207 | -0.0233117 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0229884 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0229163 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0224435 |
| CRPPA | CDP-L-ribitol pyrophosphorylase A | -0.0223469 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | -0.022309 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0220808 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0218514 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.0217526 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0215789 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0215654 |
| MEF2A | myocyte enhancer factor 2A | -0.02153 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.02137 |
