| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bimiralisib perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bimiralisib_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.211577 |
| SQSTM1 | sequestosome 1 | 0.104772 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0867221 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0733268 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0677143 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0616915 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0606864 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0574465 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0518384 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0492117 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0462053 |
| VMP1 | vacuole membrane protein 1 | 0.0440179 |
| WWOX | WW domain containing oxidoreductase | 0.0397479 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0376422 |
| TXNIP | thioredoxin interacting protein | 0.0361903 |
| TXNRD1 | thioredoxin reductase 1 | 0.0357474 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0353027 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.0349114 |
| CENPP | centromere protein P | 0.0344198 |
| TENM2 | teneurin transmembrane protein 2 | 0.0343356 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0339467 |
| NTN4 | netrin 4 | 0.0337407 |
| GOLGB1 | golgin B1 | 0.0335473 |
| FOXP1 | forkhead box P1 | 0.0328588 |
| RAB31 | RAB31, member RAS oncogene family | 0.0325655 |
| SIK2 | salt-inducible kinase 2 | 0.0324548 |
| NBEA | neurobeachin | 0.0324382 |
| SCAPER | S-phase cyclin A-associated protein in the ER | 0.0320724 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0315878 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0306764 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0298362 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0296853 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.029293 |
| BRD2 | bromodomain containing 2 | 0.0286196 |
| PHF3 | PHD finger protein 3 | 0.0285987 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0282519 |
| AEBP2 | AE binding protein 2 | 0.0282065 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0278571 |
| RPS12 | ribosomal protein S12 | 0.0277744 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0277656 |
| DST | dystonin | 0.0272259 |
| MED13L | mediator complex subunit 13-like | 0.026768 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | 0.0264131 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0263948 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0257346 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0256039 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | 0.025306 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0252055 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0251295 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0250927 |
| TLE4 | transducin-like enhancer of split 4 | 0.0245649 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.0235525 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | 0.0233118 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0231882 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.023079 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.0228918 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0223733 |
| TOR1AIP2 | torsin A interacting protein 2 | 0.0222842 |
| MED13 | mediator complex subunit 13 | 0.021896 |
| WDR70 | WD repeat domain 70 | 0.0217673 |
| RPS25 | ribosomal protein S25 | 0.0217203 |
| RPS3 | ribosomal protein S3 | 0.0216968 |
| CREBBP | CREB binding protein | 0.0213073 |
| EEA1 | early endosome antigen 1 | 0.0211112 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0209918 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0209094 |
| ACYP2 | acylphosphatase 2, muscle type | 0.0207777 |
| DENND5B | DENN/MADD domain containing 5B | 0.0206463 |
| FTL | ferritin, light polypeptide | 0.0206223 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0206048 |
| GLCCI1 | glucocorticoid induced 1 | 0.0205972 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0205686 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0204574 |
| INTS6 | integrator complex subunit 6 | 0.0204468 |
| B2M | beta-2-microglobulin | 0.0204026 |
| CUX1 | cut-like homeobox 1 | 0.0203738 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0202612 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0202045 |
| SPAG16 | sperm associated antigen 16 | 0.0201842 |
| RABGAP1 | RAB GTPase activating protein 1 | 0.0193672 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | 0.0192183 |
| SMYD3 | SET and MYND domain containing 3 | 0.0190783 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0190144 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.018975 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0188052 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0187107 |
| FNIP1 | folliculin interacting protein 1 | 0.0187061 |
| BPTF | bromodomain PHD finger transcription factor | 0.0185296 |
| LMO7 | LIM domain 7 | 0.0184688 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0184297 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0184206 |
| RPL36 | ribosomal protein L36 | 0.0183347 |
| STAT5B | signal transducer and activator of transcription 5B | 0.0181542 |
| ATXN7L1 | ataxin 7-like 1 | 0.0178284 |
| MSI2 | musashi RNA-binding protein 2 | 0.0177381 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.0175802 |
| GOLM2 | golgi membrane protein 2 | 0.0175494 |
| FLCN | folliculin | 0.0172825 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0172237 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0171663 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | -0.162211 |
| VIM | vimentin | -0.125178 |
| HMGA2 | high mobility group AT-hook 2 | -0.109255 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.105168 |
| TMSB10 | thymosin beta 10 | -0.102055 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0942775 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0933035 |
| FLNB | filamin B, beta | -0.0918442 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0899418 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0856659 |
| FMNL2 | formin-like 2 | -0.0847465 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0784574 |
| ANGPTL4 | angiopoietin-like 4 | -0.075137 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0749641 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0694611 |
| CAPRIN2 | caprin family member 2 | -0.0682786 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0681614 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0679333 |
| NDRG1 | N-myc downstream regulated 1 | -0.0665117 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0661739 |
| PTMA | prothymosin, alpha | -0.0658006 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0655136 |
| DNER | delta/notch-like EGF repeat containing | -0.0620073 |
| PKM | pyruvate kinase, muscle | -0.0619131 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.060983 |
| ASPH | aspartate beta-hydroxylase | -0.0590614 |
| MT2A | metallothionein 2A | -0.0575741 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0564333 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0561786 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0556302 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0545503 |
| SNX14 | sorting nexin 14 | -0.0542217 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0532731 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0532147 |
| MYO9B | myosin IXB | -0.0529567 |
| MSN | moesin | -0.0511411 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.050849 |
| CD44 | CD44 molecule (Indian blood group) | -0.0506813 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0501274 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.049841 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0479709 |
| DTNA | dystrobrevin, alpha | -0.0477982 |
| NAV2 | neuron navigator 2 | -0.0476186 |
| EGR1 | early growth response 1 | -0.0473066 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0468187 |
| SETD5 | SET domain containing 5 | -0.0453466 |
| MAP1B | microtubule-associated protein 1B | -0.0452099 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0448006 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.044716 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0441857 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.043296 |
| ACTN1 | actinin, alpha 1 | -0.042915 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0425471 |
| PYGL | phosphorylase, glycogen, liver | -0.042367 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0422939 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0415596 |
| NIBAN2 | niban apoptosis regulator 2 | -0.0415084 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0413431 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0409289 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0408901 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0403775 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0403481 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.0402873 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0396179 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0387775 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0387315 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0379165 |
| SPAG9 | sperm associated antigen 9 | -0.0378476 |
| PTK2 | protein tyrosine kinase 2 | -0.037561 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0374807 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0373857 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0373806 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0371362 |
| MCL1 | myeloid cell leukemia 1 | -0.0370999 |
| NGLY1 | N-glycanase 1 | -0.0369904 |
| RGS17 | regulator of G-protein signaling 17 | -0.0369888 |
| POTEF | POTE ankyrin domain family, member F | -0.0368163 |
| ITGB5 | integrin, beta 5 | -0.0362265 |
| ACER3 | alkaline ceramidase 3 | -0.0361131 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0361014 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0358306 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0356942 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0349654 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0339504 |
| FMN1 | formin 1 | -0.0338406 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0338221 |
| CALU | calumenin | -0.0335871 |
| NKTR | natural killer cell triggering receptor | -0.0332855 |
| NHSL1 | NHS-like 1 | -0.0330269 |
| ANKRD37 | ankyrin repeat domain 37 | -0.0330059 |
| IER3 | immediate early response 3 | -0.0329233 |
| ADM | adrenomedullin | -0.0328832 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0328608 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0326812 |
| PARD3 | par-3 family cell polarity regulator | -0.0326715 |
| ATXN1 | ataxin 1 | -0.0325181 |
| PFN1 | profilin 1 | -0.0325 |
| KIAA1671 | KIAA1671 | -0.032368 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0318363 |
| SEC24A | SEC24 family member A | -0.0318247 |
