| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bimiralisib perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bimiralisib_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EXT1 | exostosin glycosyltransferase 1 | 0.116231 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0919483 |
| STC2 | stanniocalcin 2 | 0.0772544 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0721886 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0649535 |
| NRG1 | neuregulin 1 | 0.0636308 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0606885 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0583575 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.056858 |
| EFNA5 | ephrin-A5 | 0.0568369 |
| PALLD | palladin, cytoskeletal associated protein | 0.056308 |
| B2M | beta-2-microglobulin | 0.055381 |
| INTS6 | integrator complex subunit 6 | 0.0524642 |
| VCL | vinculin | 0.0502251 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0497895 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0478225 |
| PLIN2 | perilipin 2 | 0.0471175 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0465904 |
| MYOF | myoferlin | 0.0464976 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0464062 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0450655 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0443124 |
| RASAL2 | RAS protein activator like 2 | 0.043905 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0432822 |
| GPC6 | glypican 6 | 0.0419555 |
| RPL31 | ribosomal protein L31 | 0.0415239 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0414352 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0413893 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0395519 |
| ENO1 | enolase 1, (alpha) | 0.0390751 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0390352 |
| FTL | ferritin, light polypeptide | 0.0390122 |
| NXN | nucleoredoxin | 0.0389541 |
| DSTN | destrin (actin depolymerizing factor) | 0.0389507 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0380859 |
| RPS12 | ribosomal protein S12 | 0.0380427 |
| RAI14 | retinoic acid induced 14 | 0.0374992 |
| HMGA2 | high mobility group AT-hook 2 | 0.0372412 |
| NTN4 | netrin 4 | 0.0369251 |
| AEBP2 | AE binding protein 2 | 0.0367068 |
| GOLGB1 | golgin B1 | 0.0360728 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0360538 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0356141 |
| RPL37A | ribosomal protein L37a | 0.0348154 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0345364 |
| IFI44L | interferon-induced protein 44-like | 0.0340415 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0335113 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0333043 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0324807 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0319871 |
| FHIT | fragile histidine triad | 0.0317868 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0317777 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0316949 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0315408 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0306998 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0298019 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0293964 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0290697 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0289048 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0288535 |
| RAB10 | RAB10, member RAS oncogene family | 0.0287332 |
| MYADM | myeloid-associated differentiation marker | 0.0285833 |
| ACTG1 | actin gamma 1 | 0.0284315 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0282967 |
| TGFB2 | transforming growth factor, beta 2 | 0.0275286 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0274977 |
| RPS8 | ribosomal protein S8 | 0.0273689 |
| EGFR | epidermal growth factor receptor | 0.0272582 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0270901 |
| SIRT1 | sirtuin 1 | 0.0270088 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.026731 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0266499 |
| TXNIP | thioredoxin interacting protein | 0.0262965 |
| MYO1E | myosin IE | 0.0260253 |
| VEGFA | vascular endothelial growth factor A | 0.0258499 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.025732 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0257175 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.0257005 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0250129 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0248885 |
| RPS3 | ribosomal protein S3 | 0.0248099 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0247994 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0245218 |
| SVIL | supervillin | 0.0244608 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0244351 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0242961 |
| NOVA1 | neuro-oncological ventral antigen 1 | 0.0241835 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0241297 |
| RPS27 | ribosomal protein S27 | 0.0240226 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0240222 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0239506 |
| RPS23 | ribosomal protein S23 | 0.0237413 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0235898 |
| ATF6 | activating transcription factor 6 | 0.0235599 |
| AHI1 | Abelson helper integration site 1 | 0.0234676 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0234127 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0233535 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0232093 |
| FHL2 | four and a half LIM domains 2 | 0.0231835 |
| MCL1 | myeloid cell leukemia 1 | 0.0231497 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.325379 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.13204 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.122042 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.093609 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0906013 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0888307 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0887062 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0758235 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0717281 |
| FN1 | fibronectin 1 | -0.0678332 |
| PELO | pelota homolog (Drosophila) | -0.0627554 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0600153 |
| CENPF | centromere protein F, 350/400kDa | -0.0592684 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0587268 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0569087 |
| AHR | aryl hydrocarbon receptor | -0.0533129 |
| OGA | O-GlcNAcase | -0.0527157 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0526172 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0518333 |
| MKI67 | marker of proliferation Ki-67 | -0.0497676 |
| WDR45B | WD repeat domain 45B | -0.0488418 |
| CANX | calnexin | -0.0487653 |
| SPAG9 | sperm associated antigen 9 | -0.0484318 |
| ITGA1 | integrin, alpha 1 | -0.047467 |
| EREG | epiregulin | -0.0435994 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0435768 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0433763 |
| SMOX | spermine oxidase | -0.0430731 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0430338 |
| RBM39 | RNA binding motif protein 39 | -0.042847 |
| ARF1 | ADP-ribosylation factor 1 | -0.0422215 |
| ETNK1 | ethanolamine kinase 1 | -0.0417037 |
| PTMA | prothymosin, alpha | -0.0412602 |
| CD44 | CD44 molecule (Indian blood group) | -0.0411095 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0409865 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0389203 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0384439 |
| TMSB4X | thymosin beta 4, X-linked | -0.0383724 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0376719 |
| HELZ | helicase with zinc finger | -0.0370117 |
| H1-0 | H1.0 linker histone | -0.0368909 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0364063 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0363028 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0361466 |
| TFG | TRK-fused gene | -0.0361353 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0360864 |
| PKM | pyruvate kinase, muscle | -0.035819 |
| ZNF292 | zinc finger protein 292 | -0.0354707 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0350621 |
| SUCO | SUN domain containing ossification factor | -0.0350589 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0346879 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0346577 |
| RNF145 | ring finger protein 145 | -0.0345687 |
| NUP58 | nucleoporin 58 | -0.0344467 |
| NEK7 | NIMA-related kinase 7 | -0.0340973 |
| HPCAL1 | hippocalcin-like 1 | -0.0340955 |
| COPA | coatomer protein complex, subunit alpha | -0.0340693 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0340587 |
| USP3 | ubiquitin specific peptidase 3 | -0.0340135 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0334168 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0333111 |
| GOLT1B | golgi transport 1B | -0.0331701 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0330075 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0328788 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0323848 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0321061 |
| RBM25 | RNA binding motif protein 25 | -0.03201 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0316766 |
| RLF | rearranged L-myc fusion | -0.031208 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0311469 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0311328 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0309895 |
| ANLN | anillin, actin binding protein | -0.0307201 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0306141 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0305243 |
| CDC27 | cell division cycle 27 | -0.0303426 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0302497 |
| COG5 | component of oligomeric golgi complex 5 | -0.0299768 |
| RTN4 | reticulon 4 | -0.029417 |
| FNBP1 | formin binding protein 1 | -0.0290571 |
| SEPTIN7 | septin 7 | -0.0288947 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0286193 |
| TMEM156 | transmembrane protein 156 | -0.0282697 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0281124 |
| PTK2 | protein tyrosine kinase 2 | -0.0280675 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.0280237 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.0279543 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0279344 |
| S100A6 | S100 calcium binding protein A6 | -0.0278339 |
| PIM3 | Pim-3 proto-oncogene, serine/threonine kinase | -0.0276979 |
| ETV6 | ets variant 6 | -0.0274911 |
| CDC73 | cell division cycle 73 | -0.0270612 |
| TXNRD1 | thioredoxin reductase 1 | -0.0268141 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0267301 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0263978 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0263004 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0261701 |
| RHEB | Ras homolog enriched in brain | -0.0258998 |
| FOXO3 | forkhead box O3 | -0.0258138 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.025772 |
