Bipolar Disorder_frontal cortex_GSE5389 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE5389
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Genes

600 genes differentially expressed during Bipolar Disorder_frontal cortex_GSE5389 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
RBM19 RNA binding motif protein 19 3.75111
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 3.43596
SLCO5A1 solute carrier organic anion transporter family, member 5A1 3.17688
KIF18A kinesin family member 18A 2.9782
CXCL5 chemokine (C-X-C motif) ligand 5 2.8208
HEMK1 HemK methyltransferase family member 1 2.80597
PRSS12 protease, serine, 12 (neurotrypsin, motopsin) 2.80132
CCHCR1 coiled-coil alpha-helical rod protein 1 2.79923
ADAM19 ADAM metallopeptidase domain 19 2.79452
PGA5 pepsinogen 5, group I (pepsinogen A) 2.75058
TGM2 transglutaminase 2 2.74284
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 2.73487
RBMS2 RNA binding motif, single stranded interacting protein 2 2.69072
TSPAN2 tetraspanin 2 2.68247
ZNF813 zinc finger protein 813 2.67579
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 2.6164
ZKSCAN5 zinc finger with KRAB and SCAN domains 5 2.61404
TRIM29 tripartite motif containing 29 2.59808
GPRC5A G protein-coupled receptor, class C, group 5, member A 2.58194
KIF11 kinesin family member 11 2.57257
SYNC syncoilin, intermediate filament protein 2.50421
LRRC63 leucine rich repeat containing 63 2.50076
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 2.49255
SIRT5 sirtuin 5 2.4841
PGAP3 post-GPI attachment to proteins 3 2.46993
CPT1A carnitine palmitoyltransferase 1A (liver) 2.43605
ASMT acetylserotonin O-methyltransferase 2.38994
ZNF219 zinc finger protein 219 2.38108
RPS4XP9 ribosomal protein S4X pseudogene 9 2.36962
CLEC4M C-type lectin domain family 4, member M 2.36252
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2 2.34047
FCMR Fc fragment of IgM receptor 2.33356
NCLN nicalin 2.33335
INVS inversin 2.31156
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 2.31018
MNS1 meiosis-specific nuclear structural 1 2.30106
PQLC3 PQ loop repeat containing 3 2.29004
IGFBP1 insulin-like growth factor binding protein 1 2.27944
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) 2.26555
KRT35 keratin 35, type I 2.26044
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 2.24979
PLSCR3 phospholipid scramblase 3 2.24691
ZNF230 zinc finger protein 230 2.2351
MUC4 mucin 4, cell surface associated 2.22497
FZD1 frizzled class receptor 1 2.22088
RANBP10 RAN binding protein 10 2.21882
MAGEB1 melanoma antigen family B1 2.21569
PPBPP2 pro-platelet basic protein pseudogene 2 2.21414
STEAP3 STEAP family member 3, metalloreductase 2.21052
KIAA1456 KIAA1456 2.20813
PTGER3 prostaglandin E receptor 3 (subtype EP3) 2.20798
RPL4 ribosomal protein L4 2.20467
TRIM48 tripartite motif containing 48 2.20157
STX2 syntaxin 2 2.20028
HIST1H3F histone cluster 1, H3f 2.19942
PUS3 pseudouridylate synthase 3 2.19831
MAPK7 mitogen-activated protein kinase 7 2.19007
KIR3DX1 killer cell immunoglobulin-like receptor, three domains, X1 2.18301
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.18207
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative) 2.17431
TAPT1 transmembrane anterior posterior transformation 1 2.16655
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 2.16382
RAVER2 ribonucleoprotein, PTB-binding 2 2.15228
PDGFRL platelet-derived growth factor receptor-like 2.15071
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 2.12414
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like 2.11964
WHSC1 Wolf-Hirschhorn syndrome candidate 1 2.11692
OR1D4 olfactory receptor, family 1, subfamily D, member 4 (gene/pseudogene) 2.10764
CASP4 caspase 4, apoptosis-related cysteine peptidase 2.1075
ACACA acetyl-CoA carboxylase alpha 2.09322
PKNOX1 PBX/knotted 1 homeobox 1 2.0868
MPPE1 metallophosphoesterase 1 2.07503
CAV3 caveolin 3 2.07491
ZNF710 zinc finger protein 710 2.07335
ADCY9 adenylate cyclase 9 2.07283
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 2.07005
HIST1H3A histone cluster 1, H3a 2.06994
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) 2.06787
ADCY6 adenylate cyclase 6 2.06741
SCN9A sodium channel, voltage gated, type IX alpha subunit 2.06319
HOXB7 homeobox B7 2.05652
IFNA8 interferon, alpha 8 2.05437
UTS2 urotensin 2 2.044
ACOX3 acyl-CoA oxidase 3, pristanoyl 2.04319
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 2.03937
IGKC immunoglobulin kappa constant 2.03041
TNP1 transition protein 1 (during histone to protamine replacement) 2.03004
KIAA0040 KIAA0040 2.02264
MYH8 myosin, heavy chain 8, skeletal muscle, perinatal 2.02091
STK17B serine/threonine kinase 17b 2.01432
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 2.00182
EIF3F eukaryotic translation initiation factor 3, subunit F 1.99133
EVC Ellis van Creveld protein 1.98236
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 1.98055
NEU3 sialidase 3 (membrane sialidase) 1.97992
EFNA4 ephrin-A4 1.97872
MZF1 myeloid zinc finger 1 1.97556
TMEM71 transmembrane protein 71 1.97498
PEMT phosphatidylethanolamine N-methyltransferase 1.97116
LOC1720 dihydrofolate reductase pseudogene 1.96763
IFNA6 interferon, alpha 6 1.96596
DDIT3 DNA-damage-inducible transcript 3 1.95984
SMIM2 small integral membrane protein 2 1.95978
ZCCHC14 zinc finger, CCHC domain containing 14 1.95322
IL10 interleukin 10 1.95205
AFF2 AF4/FMR2 family, member 2 1.94712
CENPF centromere protein F, 350/400kDa 1.94679
ALG3 ALG3, alpha-1,3- mannosyltransferase 1.946
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1 1.93854
OR3A1 olfactory receptor, family 3, subfamily A, member 1 1.9377
CDK2 cyclin-dependent kinase 2 1.93667
C3ORF52 chromosome 3 open reading frame 52 1.93579
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 1.91688
LOC57399 uncharacterized gastric protein ZA52P 1.91486
PIP prolactin-induced protein 1.91003
EDEM2 ER degradation enhancer, mannosidase alpha-like 2 1.90419
ZNF839 zinc finger protein 839 1.8948
TBC1D22B TBC1 domain family, member 22B 1.89459
SMR3B submaxillary gland androgen regulated protein 3B 1.89438
PITX2 paired-like homeodomain 2 1.89218
TMEM80 transmembrane protein 80 1.88811
INADL InaD-like (Drosophila) 1.88366
HS3ST3B1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 1.88284
ARG1 arginase 1 1.88219
SLC25A31 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31 1.88214
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 1.87917
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 1.87833
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) 1.87629
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7 1.87602
GYPA glycophorin A (MNS blood group) 1.87581
LCK LCK proto-oncogene, Src family tyrosine kinase 1.87226
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal) 1.86519
TLL1 tolloid-like 1 1.86422
PSG3 pregnancy specific beta-1-glycoprotein 3 1.86371
GPR18 G protein-coupled receptor 18 1.86325
IAPP islet amyloid polypeptide 1.86045
TCP10L t-complex 10-like 1.85817
PLAUR plasminogen activator, urokinase receptor 1.84997
GTF2A1 general transcription factor IIA, 1, 19/37kDa 1.84932
ZNF750 zinc finger protein 750 1.84712
NOD2 nucleotide-binding oligomerization domain containing 2 1.84659
EN1 engrailed homeobox 1 1.84332
ZNF557 zinc finger protein 557 1.8243
CDSN corneodesmosin 1.81553
SIRT6 sirtuin 6 1.81303
SEC24D SEC24 family member D 1.80922
EPYC epiphycan 1.80462
ERCC1 excision repair cross-complementation group 1 1.80272
MYO15A myosin XVA 1.79856
CENPI centromere protein I 1.79495
CR2 complement component (3d/Epstein Barr virus) receptor 2 1.789
CA12 carbonic anhydrase XII 1.78541
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7 1.78487
MPZL2 myelin protein zero-like 2 1.78304
DOLK dolichol kinase 1.78256
MYBPC2 myosin binding protein C, fast type 1.78065
RIPK2 receptor-interacting serine-threonine kinase 2 1.77822
PKLR pyruvate kinase, liver and RBC 1.77507
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 1.77368
DEC1 deleted in esophageal cancer 1 1.77261
DPH2 DPH2 homolog (S. cerevisiae) 1.77257
TRIM15 tripartite motif containing 15 1.77227
WNT9A wingless-type MMTV integration site family, member 9A 1.77151
XKR8 XK, Kell blood group complex subunit-related family, member 8 1.76841
SNED1 sushi, nidogen and EGF-like domains 1 1.76802
GCM2 glial cells missing homolog 2 (Drosophila) 1.76587
TSHR thyroid stimulating hormone receptor 1.76485
GFRA3 GDNF family receptor alpha 3 1.76461
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 1.75902
LOC100506469 1.75871
MAB21L2 mab-21-like 2 (C. elegans) 1.75779
PP14571 uncharacterized LOC100130449 1.75255
ADGRV1 adhesion G protein-coupled receptor V1 1.7511
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 1.7508
TK1 thymidine kinase 1, soluble 1.74788
GMPS guanine monphosphate synthase 1.74777
PLCG1 phospholipase C, gamma 1 1.74685
NXF2 nuclear RNA export factor 2 1.74632
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 1.74524
CALCB calcitonin-related polypeptide beta 1.74446
HIST1H2BM histone cluster 1, H2bm 1.7426
MSX2 msh homeobox 2 1.74206
GOSR2 golgi SNAP receptor complex member 2 1.74057
ZNF419 zinc finger protein 419 1.73988
SPANXC SPANX family, member C 1.73982
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal) 1.73869
PLA2G3 phospholipase A2, group III 1.73483
NHEJ1 nonhomologous end-joining factor 1 1.73458
PLXNB2 plexin B2 1.73436
PDPR pyruvate dehydrogenase phosphatase regulatory subunit 1.72993
MLXIP MLX interacting protein 1.72933
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A 1.72687
TEAD3 TEA domain family member 3 1.7252
TSPY1 testis specific protein, Y-linked 1 1.72268
FGF6 fibroblast growth factor 6 1.71802
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 1.71082
ZNF257 zinc finger protein 257 1.70947
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 1.70904
AGTR1 angiotensin II receptor, type 1 1.7073
GINS2 GINS complex subunit 2 (Psf2 homolog) 1.7044
STAP1 signal transducing adaptor family member 1 1.70299
MB myoglobin 1.70203
RAG2 recombination activating gene 2 1.70002
GALNS galactosamine (N-acetyl)-6-sulfatase 1.69807
RCVRN recoverin 1.69738
CTSS cathepsin S 1.69663
TFEC transcription factor EC 1.69355
DRD5 dopamine receptor D5 1.692
SIM1 single-minded family bHLH transcription factor 1 1.69092
MUC1 mucin 1, cell surface associated 1.68969
FBXO42 F-box protein 42 1.68735
OR10C1 olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene) 1.68669
S100A5 S100 calcium binding protein A5 1.68623
TEAD4 TEA domain family member 4 1.68528
MGAM maltase-glucoamylase 1.68465
C9 complement component 9 1.68413
HDC histidine decarboxylase 1.68313
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 1.68084
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2 1.68078
CDY1 chromodomain protein, Y-linked, 1 1.67759
SLC44A4 solute carrier family 44, member 4 1.67193
CEP152 centrosomal protein 152kDa 1.67136
MYH4 myosin, heavy chain 4, skeletal muscle 1.67059
IL19 interleukin 19 1.66714
MMP2 matrix metallopeptidase 2 1.66465
MTMR7 myotubularin related protein 7 1.66331
ASB4 ankyrin repeat and SOCS box containing 4 1.66189
WISP3 WNT1 inducible signaling pathway protein 3 1.66168
F5 coagulation factor V (proaccelerin, labile factor) 1.66113
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 1.65779
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) 1.65607
BMP2K BMP2 inducible kinase 1.65581
FOXN2 forkhead box N2 1.65571
KNTC1 kinetochore associated 1 1.65452
TGFB2 transforming growth factor, beta 2 1.65203
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 1.64721
LRRC3B leucine rich repeat containing 3B 1.64373
PDLIM3 PDZ and LIM domain 3 1.64123
RARS2 arginyl-tRNA synthetase 2, mitochondrial 1.64093
KCNK5 potassium channel, two pore domain subfamily K, member 5 1.63781
RBM47 RNA binding motif protein 47 1.63712
TMEM156 transmembrane protein 156 1.63648
COL14A1 collagen, type XIV, alpha 1 1.63606
SLC26A10 solute carrier family 26, member 10 1.63413
CYTIP cytohesin 1 interacting protein 1.6339
PIGC phosphatidylinositol glycan anchor biosynthesis, class C 1.63225
MARCH3 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase 1.62705
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 1.62483
JCHAIN joining chain of multimeric IgA and IgM 1.62443
DAZL deleted in azoospermia-like 1.62431
RAB3IP RAB3A interacting protein 1.62344
RBFA ribosome binding factor A (putative) 1.62147
TTTY1 testis-specific transcript, Y-linked 1 (non-protein coding) 1.62084
CLDN15 claudin 15 1.6193
HPX hemopexin 1.61871
ZNF208 zinc finger protein 208 1.61849
HOXD3 homeobox D3 1.61537
KCNA10 potassium channel, voltage gated shaker related subfamily A, member 10 1.61409
PLAU plasminogen activator, urokinase 1.61398
ADAM2 ADAM metallopeptidase domain 2 1.61396
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase) 1.61382
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime 1.61361
ZNF407 zinc finger protein 407 1.61356
ADAM12 ADAM metallopeptidase domain 12 1.60964
STX17 syntaxin 17 1.6095
HHLA1 HERV-H LTR-associating 1 1.60886
IGKV1OR2-108 immunoglobulin kappa variable 1/OR2-108 (non-functional) 1.6067
MTTP microsomal triglyceride transfer protein 1.60438
LAS1L LAS1-like (S. cerevisiae) 1.60412
INPP5B inositol polyphosphate-5-phosphatase, 75kDa 1.60304
MFAP5 microfibrillar associated protein 5 1.60183
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 1.60101
CPS1-IT1 CPS1 intronic transcript 1 1.60065
LAMC3 laminin, gamma 3 1.59611
CHEK2 checkpoint kinase 2 1.59581
LGALS4 lectin, galactoside-binding, soluble, 4 1.5955
TNN tenascin N 1.59342
OR2J2 olfactory receptor, family 2, subfamily J, member 2 1.592
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1 1.59152
RBM34 RNA binding motif protein 34 1.59109
ADAM29 ADAM metallopeptidase domain 29 1.58988
NPEPL1 aminopeptidase-like 1 1.58651
ETHE1 ethylmalonic encephalopathy 1 1.5864
TEX13B testis expressed 13B 1.58578
TRIM38 tripartite motif containing 38 1.58506
KLHL18 kelch-like family member 18 1.58506
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 1.58499
CTRL chymotrypsin-like 1.58104
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 1.57903
CDC25C cell division cycle 25C 1.57851
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.57673
MBL1P mannose-binding lectin (protein A) 1, pseudogene 1.57611
OVGP1 oviductal glycoprotein 1, 120kDa 1.57609
COL4A4 collagen, type IV, alpha 4 1.57519
KIF23 kinesin family member 23 1.57456
ZNF468 zinc finger protein 468 1.57165
POMT1 protein-O-mannosyltransferase 1 1.57147
ANXA2P2 annexin A2 pseudogene 2 1.5701
TMPRSS4 transmembrane protease, serine 4 1.56979
HIST1H2BH histone cluster 1, H2bh 1.5697

decreased expression

Symbol Name Standardized Value
BCAP29 B-cell receptor-associated protein 29 -2.70861
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 -2.51098
CEP104 centrosomal protein 104kDa -2.465
ING4 inhibitor of growth family, member 4 -2.44057
MCF2L2 MCF.2 cell line derived transforming sequence-like 2 -2.37296
BLZF1 basic leucine zipper nuclear factor 1 -2.32944
TEP1 telomerase-associated protein 1 -2.31389
CXCL6 chemokine (C-X-C motif) ligand 6 -2.29958
CALM2 calmodulin 2 (phosphorylase kinase, delta) -2.29294
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme -2.29145
SELE selectin E -2.2509
AKAP11 A kinase (PRKA) anchor protein 11 -2.22434
IREB2 iron-responsive element binding protein 2 -2.21475
FBXO4 F-box protein 4 -2.18642
GK glycerol kinase -2.18339
MTRF1L mitochondrial translational release factor 1-like -2.16604
LPAR4 lysophosphatidic acid receptor 4 -2.14215
RAB11FIP1 RAB11 family interacting protein 1 (class I) -2.08733
TFAM transcription factor A, mitochondrial -2.07919
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) -2.06978
RABGAP1 RAB GTPase activating protein 1 -2.069
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 -2.06675
NCOA2 nuclear receptor coactivator 2 -2.04977
KLF9 Kruppel-like factor 9 -2.04943
FAM162A family with sequence similarity 162, member A -2.04146
IL26 interleukin 26 -2.02483
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD) -1.99999
CYLD cylindromatosis (turban tumor syndrome) -1.99908
ARHGAP26 Rho GTPase activating protein 26 -1.99063
MAGEC1 melanoma antigen family C1 -1.98564
ANKRD10 ankyrin repeat domain 10 -1.97493
INCENP inner centromere protein antigens 135/155kDa -1.96743
CNOT4 CCR4-NOT transcription complex, subunit 4 -1.96238
TBP TATA box binding protein -1.95732
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) -1.94615
FAM63B family with sequence similarity 63, member B -1.92902
MSTN myostatin -1.92257
UBE2D1 ubiquitin-conjugating enzyme E2D 1 -1.91854
LOC440434 aminopeptidase puromycin sensitive pseudogene -1.90512
PPARA peroxisome proliferator-activated receptor alpha -1.8916
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein -1.88175
PCDHB13 protocadherin beta 13 -1.88064
TRAC T cell receptor alpha constant -1.85837
MBTD1 mbt domain containing 1 -1.84554
FMO3 flavin containing monooxygenase 3 -1.82609
C6ORF223 chromosome 6 open reading frame 223 -1.8217
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 -1.81816
CELF1 CUGBP, Elav-like family member 1 -1.80637
DPPA4 developmental pluripotency associated 4 -1.79057
JAK2 Janus kinase 2 -1.7883
ZNF394 zinc finger protein 394 -1.77165
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome) -1.77128
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 -1.76658
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial -1.76591
SLC26A3 solute carrier family 26 (anion exchanger), member 3 -1.76103
FBN2 fibrillin 2 -1.75574
SOX30 SRY (sex determining region Y)-box 30 -1.75164
PPIE peptidylprolyl isomerase E (cyclophilin E) -1.7505
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial -1.72613
FAM69A family with sequence similarity 69, member A -1.72333
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 -1.71981
PRIM2 primase, DNA, polypeptide 2 (58kDa) -1.71434
MYH1 myosin, heavy chain 1, skeletal muscle, adult -1.7092
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 -1.69778
SUMO2 small ubiquitin-like modifier 2 -1.69378
CSNK2A1 casein kinase 2, alpha 1 polypeptide -1.68959
CDC27 cell division cycle 27 -1.68389
ADNP2 ADNP homeobox 2 -1.6827
HAPLN1 hyaluronan and proteoglycan link protein 1 -1.67891
MAN1A2 mannosidase, alpha, class 1A, member 2 -1.67001
CKAP4 cytoskeleton-associated protein 4 -1.65724
CSDE1 cold shock domain containing E1, RNA-binding -1.65672
AFP alpha-fetoprotein -1.6538
PDCL phosducin-like -1.65181
ZNF780B zinc finger protein 780B -1.65098
ARNT aryl hydrocarbon receptor nuclear translocator -1.64995
PDCD1LG2 programmed cell death 1 ligand 2 -1.64638
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 -1.6365
C2ORF49 chromosome 2 open reading frame 49 -1.63341
SART3 squamous cell carcinoma antigen recognized by T cells 3 -1.62861
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 -1.62417
EGR2 early growth response 2 -1.62072
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 -1.61515
GJA5 gap junction protein, alpha 5, 40kDa -1.60881
MORF4L1 mortality factor 4 like 1 -1.60788
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) -1.60701
HEXA hexosaminidase A (alpha polypeptide) -1.60222
CATSPER2 cation channel, sperm associated 2 -1.59929
RAB9BP1 RAB9B, member RAS oncogene family pseudogene 1 -1.58062
PCGF1 polycomb group ring finger 1 -1.5784
STMN3 stathmin-like 3 -1.57217
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 -1.57173
CIDEA cell death-inducing DFFA-like effector a -1.56865
RUFY3 RUN and FYVE domain containing 3 -1.56701
FBXO5 F-box protein 5 -1.56167
MED13L mediator complex subunit 13-like -1.56089
POLD3 polymerase (DNA-directed), delta 3, accessory subunit -1.55732
UBFD1 ubiquitin family domain containing 1 -1.55326
RRH retinal pigment epithelium-derived rhodopsin homolog -1.54563
LCMT2 leucine carboxyl methyltransferase 2 -1.54517
KLHL11 kelch-like family member 11 -1.53424
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 -1.53332
CALU calumenin -1.53305
OR51E2 olfactory receptor, family 51, subfamily E, member 2 -1.53233
HCFC2 host cell factor C2 -1.52707
DOPEY2 dopey family member 2 -1.52576
FGF20 fibroblast growth factor 20 -1.51855
RAB27B RAB27B, member RAS oncogene family -1.51463
TRIM33 tripartite motif containing 33 -1.51263
BRIP1 BRCA1 interacting protein C-terminal helicase 1 -1.51079
KRT6B keratin 6B, type II -1.50367
RFX7 regulatory factor X, 7 -1.50236
CDCA8 cell division cycle associated 8 -1.49939
CD1D CD1d molecule -1.49777
MAPK14 mitogen-activated protein kinase 14 -1.49162
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila) -1.49061
DIO1 deiodinase, iodothyronine, type I -1.48916
FOXM1 forkhead box M1 -1.48596
ZNF44 zinc finger protein 44 -1.48304
ZMYM2 zinc finger, MYM-type 2 -1.48078
DDI2 DNA-damage inducible 1 homolog 2 (S. cerevisiae) -1.48051
TGOLN2 trans-golgi network protein 2 -1.47264
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 -1.47143
ZFX zinc finger protein, X-linked -1.46347
CUL4B cullin 4B -1.46101
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -1.45488
UBE3A ubiquitin protein ligase E3A -1.45484
C8ORF4 chromosome 8 open reading frame 4 -1.45457
NAP1L1 nucleosome assembly protein 1-like 1 -1.45416
GALR1 galanin receptor 1 -1.45271
OSBPL8 oxysterol binding protein-like 8 -1.4519
COPA coatomer protein complex, subunit alpha -1.45124
STX7 syntaxin 7 -1.44822
SLC25A30 solute carrier family 25, member 30 -1.44762
ZNF250 zinc finger protein 250 -1.44422
FBXO21 F-box protein 21 -1.44033
CFI complement factor I -1.43536
C2ORF44 chromosome 2 open reading frame 44 -1.43347
HEXIM1 hexamethylene bis-acetamide inducible 1 -1.43194
OSMR oncostatin M receptor -1.42451
STXBP6 syntaxin binding protein 6 (amisyn) -1.42283
MBNL1 muscleblind-like splicing regulator 1 -1.41992
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 -1.41617
USP33 ubiquitin specific peptidase 33 -1.41277
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 -1.41132
FXN frataxin -1.40659
RASAL2 RAS protein activator like 2 -1.40502
KYNU kynureninase -1.40235
CRCP CGRP receptor component -1.39862
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 -1.39264
MGC4859 uncharacterized LOC79150 -1.39112
DGKE diacylglycerol kinase, epsilon 64kDa -1.39098
NUP210 nucleoporin 210kDa -1.3902
NCK1 NCK adaptor protein 1 -1.38845
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase -1.38599
CD47 CD47 molecule -1.38393
KLHL28 kelch-like family member 28 -1.38102
C17ORF75 chromosome 17 open reading frame 75 -1.38078
MRPS18B mitochondrial ribosomal protein S18B -1.38069
ZNF16 zinc finger protein 16 -1.37649
NCL nucleolin -1.37644
CUL5 cullin 5 -1.37219
SLC30A6 solute carrier family 30 (zinc transporter), member 6 -1.37131
ATF6 activating transcription factor 6 -1.36955
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3 -1.36861
MIA2 melanoma inhibitory activity 2 -1.36234
NFE2L1 nuclear factor, erythroid 2-like 1 -1.3618
CENPJ centromere protein J -1.36
HEXA-AS1 HEXA antisense RNA 1 -1.35865
USP53 ubiquitin specific peptidase 53 -1.35783
ACTL7B actin-like 7B -1.35752
PDPN podoplanin -1.357
RIOK3 RIO kinase 3 -1.35515
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -1.35461
TUBGCP5 tubulin, gamma complex associated protein 5 -1.35366
GPR85 G protein-coupled receptor 85 -1.3532
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase -1.35244
MYB v-myb avian myeloblastosis viral oncogene homolog -1.35067
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa -1.34763
FPR2 formyl peptide receptor 2 -1.34415
LENEP lens epithelial protein -1.34333
OSBPL1A oxysterol binding protein-like 1A -1.34132
EIF1AX eukaryotic translation initiation factor 1A, X-linked -1.33384
EDNRA endothelin receptor type A -1.33372
MCM3AP minichromosome maintenance complex component 3 associated protein -1.3331
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae) -1.33151
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1 -1.32998
RECQL RecQ helicase-like -1.32874
CEP68 centrosomal protein 68kDa -1.32836
SREK1IP1 SREK1-interacting protein 1 -1.32586
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene -1.3224
IER2 immediate early response 2 -1.32159
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit -1.32137
PRDM2 PR domain containing 2, with ZNF domain -1.3203
TRBC1 T cell receptor beta constant 1 -1.32025
EDN2 endothelin 2 -1.32024
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein -1.31769
INTS7 integrator complex subunit 7 -1.31728
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 -1.31617
NR5A2 nuclear receptor subfamily 5, group A, member 2 -1.31524
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase -1.31508
BRWD1 bromodomain and WD repeat domain containing 1 -1.31487
FEZ2 fasciculation and elongation protein zeta 2 (zygin II) -1.31227
USP48 ubiquitin specific peptidase 48 -1.31185
NMT2 N-myristoyltransferase 2 -1.31095
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) -1.31077
PANK3 pantothenate kinase 3 -1.31075
RBM12B RNA binding motif protein 12B -1.30942
TCL1B T-cell leukemia/lymphoma 1B -1.30757
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding) -1.30168
ERAP1 endoplasmic reticulum aminopeptidase 1 -1.30006
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 -1.29976
ELAVL2 ELAV like neuron-specific RNA binding protein 2 -1.29731
MOB3B MOB kinase activator 3B -1.2968
ATF2 activating transcription factor 2 -1.29594
OTUD7B OTU deubiquitinase 7B -1.29553
NPVF neuropeptide VF precursor -1.29514
FGFR1 fibroblast growth factor receptor 1 -1.29202
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 -1.29132
CRX cone-rod homeobox -1.28466
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa -1.28347
CD38 CD38 molecule -1.28227
KDM6B lysine (K)-specific demethylase 6B -1.27678
WFDC2 WAP four-disulfide core domain 2 -1.27513
PRSS38 protease, serine, 38 -1.27184
FAM120A family with sequence similarity 120A -1.26964
TNIP3 TNFAIP3 interacting protein 3 -1.26944
PEX10 peroxisomal biogenesis factor 10 -1.26398
MMP10 matrix metallopeptidase 10 -1.26115
WRN Werner syndrome, RecQ helicase-like -1.25933
ACBD3 acyl-CoA binding domain containing 3 -1.25849
RAB5B RAB5B, member RAS oncogene family -1.25578
MDM4 MDM4, p53 regulator -1.25296
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 -1.25259
SNORA21 small nucleolar RNA, H/ACA box 21 -1.25186
C18ORF25 chromosome 18 open reading frame 25 -1.25079
TAOK1 TAO kinase 1 -1.25048
ADORA2A adenosine A2a receptor -1.24825
LRP12 low density lipoprotein receptor-related protein 12 -1.2466
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 -1.24618
THADA thyroid adenoma associated -1.24534
TOM1L2 target of myb1-like 2 (chicken) -1.24498
MCOLN3 mucolipin 3 -1.24363
PPP6R3 protein phosphatase 6, regulatory subunit 3 -1.24178
ZMYND8 zinc finger, MYND-type containing 8 -1.24084
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -1.24057
KIAA0100 KIAA0100 -1.23891
CALHM2 calcium homeostasis modulator 2 -1.23884
PCDHGA10 protocadherin gamma subfamily A, 10 -1.2382
SECISBP2 SECIS binding protein 2 -1.23748
PARD6B par-6 family cell polarity regulator beta -1.23538
FBXO11 F-box protein 11 -1.23264
IRGC immunity-related GTPase family, cinema -1.23148
PDE5A phosphodiesterase 5A, cGMP-specific -1.22684
ZNF573 zinc finger protein 573 -1.22425
PKM pyruvate kinase, muscle -1.22219
IL10RB interleukin 10 receptor, beta -1.22194
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 -1.22189
KCNAB3 potassium channel, voltage gated subfamily A regulatory beta subunit 3 -1.22183
TBC1D5 TBC1 domain family, member 5 -1.22146
RPL36AL ribosomal protein L36a-like -1.22122
C7ORF25 chromosome 7 open reading frame 25 -1.21712
LINC00474 long intergenic non-protein coding RNA 474 -1.21711
APOM apolipoprotein M -1.21426
ATM ATM serine/threonine kinase -1.21409
FTO fat mass and obesity associated -1.2107
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D -1.21061
PTGFR prostaglandin F receptor (FP) -1.20885
FABP1 fatty acid binding protein 1, liver -1.20747
POGZ pogo transposable element with ZNF domain -1.2074
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 -1.20696
RAB14 RAB14, member RAS oncogene family -1.20674
NFX1 nuclear transcription factor, X-box binding 1 -1.20198
REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae) -1.20186
POMP proteasome maturation protein -1.20098
CHD9 chromodomain helicase DNA binding protein 9 -1.20094
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) -1.20031
RBM26 RNA binding motif protein 26 -1.19971
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 -1.19889
RAD54L RAD54-like (S. cerevisiae) -1.19851
ENSA endosulfine alpha -1.19814
MYH7B myosin, heavy chain 7B, cardiac muscle, beta -1.19691
ADCY2 adenylate cyclase 2 (brain) -1.19589
AKT2 v-akt murine thymoma viral oncogene homolog 2 -1.19046
ANGEL1 angel homolog 1 (Drosophila) -1.1899
ZNF500 zinc finger protein 500 -1.18861
CDH3 cadherin 3, type 1, P-cadherin (placental) -1.18683
VAMP4 vesicle-associated membrane protein 4 -1.18644
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1 -1.18553
ID2B inhibitor of DNA binding 2B, dominant negative helix-loop-helix protein (pseudogene) -1.18392
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) -1.18332
SLC16A6 solute carrier family 16, member 6 -1.18001
PTK7 protein tyrosine kinase 7 (inactive) -1.17969
BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1 -1.1778
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4 -1.17702
RPH3AL rabphilin 3A-like (without C2 domains) -1.17529
MYO1B myosin IB -1.17507
WWC2 WW and C2 domain containing 2 -1.17439
SPAG11B sperm associated antigen 11B -1.17438
GPM6A glycoprotein M6A -1.17267
Funding