| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bisoprolol (hemifumarate) perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bisoprolol (hemifumarate)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.21312 |
| FBN1 | fibrillin 1 | 0.118156 |
| PLAT | plasminogen activator, tissue | 0.103869 |
| COL3A1 | collagen, type III, alpha 1 | 0.0925961 |
| THBS2 | thrombospondin 2 | 0.0781036 |
| PODXL | podocalyxin-like | 0.0671256 |
| LOXL2 | lysyl oxidase-like 2 | 0.0550694 |
| NAV1 | neuron navigator 1 | 0.0469347 |
| APP | amyloid beta (A4) precursor protein | 0.0440912 |
| CD44 | CD44 molecule (Indian blood group) | 0.0439881 |
| COL1A2 | collagen, type I, alpha 2 | 0.0437373 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0424965 |
| CTSB | cathepsin B | 0.0401555 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0389297 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0370026 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0359637 |
| FLNB | filamin B, beta | 0.035136 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0348584 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0347705 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0325175 |
| LOX | lysyl oxidase | 0.0324657 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0315556 |
| ATP13A3 | ATPase type 13A3 | 0.0297246 |
| SDC4 | syndecan 4 | 0.0295647 |
| SBF2 | SET binding factor 2 | 0.0290573 |
| HLA-B | major histocompatibility complex, class I, B | 0.0267595 |
| STC1 | stanniocalcin 1 | 0.0262605 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.025953 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0259352 |
| MT1X | metallothionein 1X | 0.0257568 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0253341 |
| TRIM56 | tripartite motif containing 56 | 0.0248428 |
| EHBP1 | EH domain binding protein 1 | 0.0245089 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0244994 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0238156 |
| AHNAK | AHNAK nucleoprotein | 0.0236542 |
| SEPTIN9 | septin 9 | 0.0235797 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0232706 |
| BPTF | bromodomain PHD finger transcription factor | 0.0229934 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0226938 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0224189 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0223575 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0221688 |
| ADAR | adenosine deaminase, RNA-specific | 0.0218463 |
| COL5A2 | collagen, type V, alpha 2 | 0.0215207 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0214387 |
| LOC112694756 | uncharaterized LOC112694756 | 0.020915 |
| FRMD5 | FERM domain containing 5 | 0.0206742 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0200608 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0192799 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0189728 |
| TXNIP | thioredoxin interacting protein | 0.0188768 |
| MPZL1 | myelin protein zero-like 1 | 0.0183712 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0182743 |
| GPC6 | glypican 6 | 0.0182584 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.018019 |
| GASK1B | golgi associated kinase 1B | 0.0177698 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0176013 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | 0.0175632 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.017158 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0171341 |
| MB21D2 | Mab-21 domain containing 2 | 0.0171177 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.0169923 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0169801 |
| ARF1 | ADP-ribosylation factor 1 | 0.0169739 |
| CLSTN2 | calsyntenin 2 | 0.0169209 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0168457 |
| OGA | O-GlcNAcase | 0.016536 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0164788 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0163849 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.016318 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0160712 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0158778 |
| TCF25 | transcription factor 25 (basic helix-loop-helix) | 0.0158563 |
| NF1 | neurofibromin 1 | 0.0158254 |
| MTSS1 | metastasis suppressor 1 | 0.0157736 |
| DNAAF9 | dynein axonemal assembly factor 9 | 0.0157382 |
| PRKD3 | protein kinase D3 | 0.0157114 |
| NPR2 | natriuretic peptide receptor 2 | 0.0156919 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0156823 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0155801 |
| SLF2 | SMC5-SMC6 complex localization factor 2 | 0.015501 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0154734 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0154219 |
| PRKCSH | protein kinase C substrate 80K-H | 0.0153652 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0153589 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0152046 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | 0.015176 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0151605 |
| MYOF | myoferlin | 0.015019 |
| EPN2 | epsin 2 | 0.0149331 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0148851 |
| TRAM2 | translocation associated membrane protein 2 | 0.0147257 |
| WDR26 | WD repeat domain 26 | 0.0146811 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | 0.0146748 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0145778 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0144439 |
| C1D | C1D nuclear receptor corepressor | 0.0144183 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0144133 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0143968 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.23078 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.220506 |
| TMSB10 | thymosin beta 10 | -0.162856 |
| VIM | vimentin | -0.125189 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.116613 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.111747 |
| CDH13 | cadherin 13 | -0.103765 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0824111 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.079765 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0696148 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0663128 |
| POTEF | POTE ankyrin domain family, member F | -0.0658075 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0641535 |
| EGFR | epidermal growth factor receptor | -0.0633062 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0630277 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0623468 |
| MAP1B | microtubule-associated protein 1B | -0.0610289 |
| LMNA | lamin A/C | -0.0589421 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0570314 |
| B2M | beta-2-microglobulin | -0.0553729 |
| COL5A1 | collagen, type V, alpha 1 | -0.0553017 |
| NDRG1 | N-myc downstream regulated 1 | -0.0531259 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0507606 |
| FTL | ferritin, light polypeptide | -0.0505077 |
| CSTB | cystatin B (stefin B) | -0.0501699 |
| COPA | coatomer protein complex, subunit alpha | -0.0491767 |
| FN1 | fibronectin 1 | -0.0449363 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.044771 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0437439 |
| RIGI | RNA sensor RIG-I | -0.0433932 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0428901 |
| RND3 | Rho family GTPase 3 | -0.0422862 |
| S100A6 | S100 calcium binding protein A6 | -0.0422515 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0406137 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0403576 |
| TAGLN2 | transgelin 2 | -0.0398517 |
| MSI2 | musashi RNA-binding protein 2 | -0.0382837 |
| HDAC9 | histone deacetylase 9 | -0.0382606 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0373807 |
| FOSL1 | FOS-like antigen 1 | -0.036962 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0350885 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0349818 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0349602 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0348382 |
| TPM4 | tropomyosin 4 | -0.0337677 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | -0.0331372 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0327371 |
| MT2A | metallothionein 2A | -0.0326041 |
| INTS6 | integrator complex subunit 6 | -0.0324344 |
| SPAG9 | sperm associated antigen 9 | -0.032161 |
| CALR | calreticulin | -0.0316715 |
| LDHA | lactate dehydrogenase A | -0.0315677 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0315157 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0312966 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0312455 |
| S100A11 | S100 calcium binding protein A11 | -0.0312223 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0311785 |
| CENPF | centromere protein F, 350/400kDa | -0.0309874 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0309077 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0306731 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0302673 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0295332 |
| EFNA5 | ephrin-A5 | -0.0291762 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0288207 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0285225 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0278711 |
| ADM | adrenomedullin | -0.0277616 |
| PFN1 | profilin 1 | -0.0277384 |
| FBXO11 | F-box protein 11 | -0.0275956 |
| SEC61G | Sec61 gamma subunit | -0.027489 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0268386 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.026816 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0266965 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0265964 |
| SP100 | SP100 nuclear antigen | -0.0264495 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0264174 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0264164 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0257351 |
| FSTL1 | follistatin-like 1 | -0.0255521 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0251108 |
| PTMA | prothymosin, alpha | -0.0249031 |
| TPI1 | triosephosphate isomerase 1 | -0.0248009 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0239742 |
| ZNF207 | zinc finger protein 207 | -0.0238678 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0237353 |
| RPS8 | ribosomal protein S8 | -0.0237252 |
| ACTG1 | actin gamma 1 | -0.0237173 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0234989 |
| PKM | pyruvate kinase, muscle | -0.0234617 |
| RACK1 | receptor for activated C kinase 1 | -0.0234299 |
| GOLGB1 | golgin B1 | -0.0234074 |
| SUCO | SUN domain containing ossification factor | -0.0233919 |
| RPL23 | ribosomal protein L23 | -0.0230008 |
| JUN | jun proto-oncogene | -0.0228853 |
| RPS3 | ribosomal protein S3 | -0.0226529 |
| CD109 | CD109 molecule | -0.0226113 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.0224398 |
| CANX | calnexin | -0.0224025 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0223035 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0222812 |
