| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bisoprolol (hemifumarate) perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bisoprolol (hemifumarate)_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.0493855 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0391816 |
| MKI67 | marker of proliferation Ki-67 | 0.0331043 |
| RPLP1 | ribosomal protein, large, P1 | 0.0288899 |
| FTL | ferritin, light polypeptide | 0.0284953 |
| RPL37 | ribosomal protein L37 | 0.0279659 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0278738 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0272803 |
| SS18 | synovial sarcoma translocation, chromosome 18 | 0.0250155 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0249791 |
| HMGA2 | high mobility group AT-hook 2 | 0.0240022 |
| EGFR | epidermal growth factor receptor | 0.0234933 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0233206 |
| STIL | SCL/TAL1 interrupting locus | 0.0230367 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | 0.0221085 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0220553 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | 0.0218194 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0217994 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.021773 |
| RAD21 | RAD21 homolog (S. pombe) | 0.021708 |
| CEP57 | centrosomal protein 57kDa | 0.0216241 |
| RTN4 | reticulon 4 | 0.0211828 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.0210145 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0209112 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0204982 |
| RPL23 | ribosomal protein L23 | 0.0204792 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0203261 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0202894 |
| FN1 | fibronectin 1 | 0.0202075 |
| CADM2 | cell adhesion molecule 2 | 0.019938 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0198562 |
| DIAPH3 | diaphanous-related formin 3 | 0.0196419 |
| AHNAK | AHNAK nucleoprotein | 0.0193738 |
| STC1 | stanniocalcin 1 | 0.0193552 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0193051 |
| H1-0 | H1.0 linker histone | 0.0192954 |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | 0.0192917 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.0192427 |
| TTK | TTK protein kinase | 0.0192011 |
| COL1A2 | collagen, type I, alpha 2 | 0.0191754 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0191661 |
| NDE1 | nudE neurodevelopment protein 1 | 0.0188953 |
| PHF14 | PHD finger protein 14 | 0.0188867 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0188391 |
| ADIPOR2 | adiponectin receptor 2 | 0.0187856 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.01866 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0186379 |
| KIF11 | kinesin family member 11 | 0.0186334 |
| KIF18A | kinesin family member 18A | 0.0186312 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0185325 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0185023 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0184559 |
| RPL36 | ribosomal protein L36 | 0.0184213 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0183931 |
| CENPE | centromere protein E, 312kDa | 0.0181801 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.017894 |
| ECT2 | epithelial cell transforming 2 | 0.0178938 |
| DST | dystonin | 0.0178464 |
| ATXN1 | ataxin 1 | 0.0177553 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.017495 |
| ST3GAL3 | ST3 beta-galactoside alpha-2,3-sialyltransferase 3 | 0.0172601 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0171618 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.016757 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0166654 |
| ELP4 | elongator acetyltransferase complex subunit 4 | 0.0166409 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0166041 |
| CLTA | clathrin, light chain A | 0.0164081 |
| KLF10 | Kruppel-like factor 10 | 0.0162739 |
| KIF18B | kinesin family member 18B | 0.0161827 |
| RPS17 | ribosomal protein S17 | 0.0160864 |
| IFT74 | intraflagellar transport 74 | 0.0158138 |
| RPL35 | ribosomal protein L35 | 0.0158098 |
| MLEC | malectin | 0.0157916 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0156633 |
| BARD1 | BRCA1 associated RING domain 1 | 0.0156595 |
| SARNP | SAP domain containing ribonucleoprotein | 0.0156534 |
| AGRN | agrin | 0.01564 |
| INHBA | inhibin, beta A | 0.015515 |
| RUNX1 | runt-related transcription factor 1 | 0.015474 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.015396 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0153502 |
| ANKRD11 | ankyrin repeat domain 11 | 0.015268 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0152366 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0151639 |
| ATN1 | atrophin 1 | 0.0150975 |
| ATP13A3 | ATPase type 13A3 | 0.0150863 |
| CDCA2 | cell division cycle associated 2 | 0.0150574 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0149362 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0149348 |
| HLA-A | major histocompatibility complex, class I, A | 0.01489 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0148361 |
| TENM3 | teneurin transmembrane protein 3 | 0.0148034 |
| UBE2V2 | ubiquitin-conjugating enzyme E2 variant 2 | 0.0147193 |
| DEPDC1B | DEP domain containing 1B | 0.014613 |
| ARHGAP35 | Rho GTPase activating protein 35 | 0.0145562 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.014434 |
| SNX1 | sorting nexin 1 | 0.0144153 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0143626 |
| ZFP36 | ZFP36 ring finger protein | 0.0142873 |
| BBX | bobby sox homolog (Drosophila) | 0.0142106 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.164683 |
| MEST | mesoderm specific transcript | -0.127773 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0918184 |
| QKI | QKI, KH domain containing, RNA binding | -0.0815704 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0617997 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0587871 |
| LDHA | lactate dehydrogenase A | -0.0556329 |
| MED13L | mediator complex subunit 13-like | -0.0537263 |
| IGF2R | insulin-like growth factor 2 receptor | -0.0534811 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0509152 |
| HMGA1 | high mobility group AT-hook 1 | -0.0493497 |
| SRPK2 | SRSF protein kinase 2 | -0.046858 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0466801 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0462223 |
| NFIB | nuclear factor I/B | -0.0459126 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0453514 |
| RPL35A | ribosomal protein L35a | -0.0440025 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0439051 |
| ENO1 | enolase 1, (alpha) | -0.0410367 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0401114 |
| IER3 | immediate early response 3 | -0.038394 |
| FOXC1 | forkhead box C1 | -0.0380258 |
| JMJD1C | jumonji domain containing 1C | -0.0372362 |
| PDGFC | platelet derived growth factor C | -0.0361634 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0358624 |
| HOXC10 | homeobox C10 | -0.0358575 |
| GOLGA4 | golgin A4 | -0.0348306 |
| PHF3 | PHD finger protein 3 | -0.0343045 |
| FCHSD2 | FCH and double SH3 domains 2 | -0.0341404 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0333126 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -0.0332836 |
| RPLP0 | ribosomal protein, large, P0 | -0.0329031 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0326872 |
| MGP | matrix Gla protein | -0.0325799 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0324298 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.032409 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0313845 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0312787 |
| POTEF | POTE ankyrin domain family, member F | -0.0306016 |
| PHIP | pleckstrin homology domain interacting protein | -0.0304456 |
| RPL7A | ribosomal protein L7a | -0.0301147 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0293102 |
| MEOX2 | mesenchyme homeobox 2 | -0.0292663 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0290956 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.028881 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0282617 |
| TRERF1 | transcriptional regulating factor 1 | -0.027481 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0274571 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0270985 |
| MEIS2 | Meis homeobox 2 | -0.0268334 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0267636 |
| PTMA | prothymosin, alpha | -0.0266592 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0266466 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0265142 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0261543 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0260401 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0259699 |
| SIK3 | SIK family kinase 3 | -0.0253405 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0252351 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0251384 |
| PCM1 | pericentriolar material 1 | -0.0250012 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0246876 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0246096 |
| TULP4 | tubby like protein 4 | -0.0244817 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | -0.0244697 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0240411 |
| NBEA | neurobeachin | -0.0239559 |
| RPS13 | ribosomal protein S13 | -0.0237397 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0234131 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.023374 |
| MDN1 | MDN1, midasin homolog (yeast) | -0.0233403 |
| IGF2 | insulin-like growth factor 2 | -0.0232735 |
| PCNX4 | pecanex 4 | -0.0230858 |
| RABGAP1 | RAB GTPase activating protein 1 | -0.0230768 |
| ITGAV | integrin, alpha V | -0.0230398 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0227788 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0225683 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0225109 |
| TCERG1 | transcription elongation regulator 1 | -0.0224773 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0224505 |
| RYBP | RING1 and YY1 binding protein | -0.0224303 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0223328 |
| SFTPA2 | surfactant protein A2 | -0.022239 |
| RPS6 | ribosomal protein S6 | -0.0220872 |
| FAM193A | family with sequence similarity 193, member A | -0.0220333 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0219006 |
| CABIN1 | calcineurin binding protein 1 | -0.0218121 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0217742 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0215981 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.0215319 |
| ANO6 | anoctamin 6 | -0.02141 |
| NCOA1 | nuclear receptor coactivator 1 | -0.0213437 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0212157 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0211608 |
| CECR2 | cat eye syndrome chromosome region, candidate 2 | -0.0210502 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | -0.0209392 |
| CALD1 | caldesmon 1 | -0.0209224 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0208493 |
| U2SURP | U2 snRNP-associated SURP domain containing | -0.0207841 |
| DIPK2A | divergent protein kinase domain 2A | -0.0207396 |
