| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bisoprolol (hemifumarate) perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bisoprolol (hemifumarate)_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMB3 | laminin, beta 3 | 0.147321 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0981368 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.091835 |
| VCAN | versican | 0.0747357 |
| LMO7 | LIM domain 7 | 0.0693749 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0575058 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0553229 |
| ANXA11 | annexin A11 | 0.0544933 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0532205 |
| PLAUR | plasminogen activator, urokinase receptor | 0.052249 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0493786 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.047556 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0467499 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0462866 |
| FOXO1 | forkhead box O1 | 0.0461129 |
| VCL | vinculin | 0.0436177 |
| CORO1C | coronin, actin binding protein, 1C | 0.0413876 |
| KLK10 | kallikrein-related peptidase 10 | 0.0407915 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0405955 |
| NPSR1 | neuropeptide S receptor 1 | 0.0396749 |
| FERMT1 | fermitin family member 1 | 0.0390591 |
| ACTN4 | actinin, alpha 4 | 0.0388339 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0372288 |
| ITGB4 | integrin, beta 4 | 0.0352832 |
| LAMA4 | laminin, alpha 4 | 0.0329968 |
| PLAT | plasminogen activator, tissue | 0.0326991 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0326228 |
| MIDN | midnolin | 0.0319876 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0302093 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0293183 |
| MYOF | myoferlin | 0.0292039 |
| PERP | PERP, TP53 apoptosis effector | 0.0291163 |
| AHNAK | AHNAK nucleoprotein | 0.0286274 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0283329 |
| TGFA | transforming growth factor, alpha | 0.0272007 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.0270677 |
| LY6E | lymphocyte antigen 6 complex, locus E | 0.0267942 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0265835 |
| KLF6 | Kruppel-like factor 6 | 0.0264024 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0246185 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0242078 |
| HYCC2 | hyccin PI4KA lipid kinase complex subunit 2 | 0.0233856 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0228507 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.0218759 |
| KRT18 | keratin 18, type I | 0.0217393 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.021448 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.021245 |
| FAT1 | FAT atypical cadherin 1 | 0.020831 |
| DUSP12 | dual specificity phosphatase 12 | 0.0204764 |
| DENND2C | DENN/MADD domain containing 2C | 0.0200274 |
| BCL2L1 | BCL2-like 1 | 0.0196764 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | 0.019362 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0188591 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0187886 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0187506 |
| THBD | thrombomodulin | 0.018494 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0184871 |
| JUP | junction plakoglobin | 0.0183653 |
| AZIN1 | antizyme inhibitor 1 | 0.0183531 |
| PRSS3 | protease, serine, 3 | 0.0183488 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.018198 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0180828 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0180676 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.0180254 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.0178846 |
| MX2 | MX dynamin-like GTPase 2 | 0.0178421 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0173566 |
| WWC1 | WW and C2 domain containing 1 | 0.0173488 |
| SNRK | SNF related kinase | 0.0173298 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0173068 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.0172593 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0171285 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0171126 |
| COL17A1 | collagen, type XVII, alpha 1 | 0.0170735 |
| ZNF292 | zinc finger protein 292 | 0.0169853 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0168553 |
| CLIC1 | chloride intracellular channel 1 | 0.0168437 |
| TLK1 | tousled-like kinase 1 | 0.0168271 |
| IER3 | immediate early response 3 | 0.0168123 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0167051 |
| SERINC5 | serine incorporator 5 | 0.0165925 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0164804 |
| FBXO34 | F-box protein 34 | 0.0162547 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0162463 |
| PGK1 | phosphoglycerate kinase 1 | 0.015902 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | 0.0157208 |
| RPS24 | ribosomal protein S24 | 0.0156491 |
| THOC2 | THO complex 2 | 0.0154644 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.015345 |
| ITGB8 | integrin, beta 8 | 0.0151946 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.015132 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0151169 |
| TJP2 | tight junction protein 2 | 0.0150997 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | 0.015063 |
| TMEM164 | transmembrane protein 164 | 0.0149168 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0148717 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 | 0.0148577 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0148319 |
| SREK1IP1 | SREK1-interacting protein 1 | 0.0147628 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0147248 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.179052 |
| EFNA5 | ephrin-A5 | -0.157695 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.144871 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.121144 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.107371 |
| TMSB10 | thymosin beta 10 | -0.102543 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.10131 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0926917 |
| RIOK3 | RIO kinase 3 | -0.0814702 |
| EGFR | epidermal growth factor receptor | -0.0763459 |
| MCL1 | myeloid cell leukemia 1 | -0.0749322 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0741489 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0733631 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0685581 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0679407 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0667918 |
| VIM | vimentin | -0.066755 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0645207 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0617201 |
| RPS2 | ribosomal protein S2 | -0.0605741 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0599386 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0590974 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0587118 |
| FAM107B | family with sequence similarity 107, member B | -0.0571233 |
| POTEF | POTE ankyrin domain family, member F | -0.0561522 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0550391 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0548442 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0543335 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0535717 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0516312 |
| RPS3 | ribosomal protein S3 | -0.0509823 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.049722 |
| ANXA2 | annexin A2 | -0.0489093 |
| MORF4L2 | mortality factor 4 like 2 | -0.0487525 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0475974 |
| RPL37A | ribosomal protein L37a | -0.0465692 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0464308 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0462832 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0456436 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0456374 |
| SBF2 | SET binding factor 2 | -0.0451294 |
| GOLGB1 | golgin B1 | -0.044932 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0447523 |
| TPM3 | tropomyosin 3 | -0.0443445 |
| DIAPH1 | diaphanous-related formin 1 | -0.0442989 |
| RPS6 | ribosomal protein S6 | -0.0436652 |
| EZR | ezrin | -0.043589 |
| PTMA | prothymosin, alpha | -0.043555 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0432291 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | -0.0430878 |
| TXNIP | thioredoxin interacting protein | -0.0428245 |
| RPS8 | ribosomal protein S8 | -0.0428221 |
| MXD1 | MAX dimerization protein 1 | -0.0419584 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0417914 |
| S100A11 | S100 calcium binding protein A11 | -0.0415588 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0414702 |
| RPS27 | ribosomal protein S27 | -0.0407092 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0385787 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0385601 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.038437 |
| PRRC2C | proline-rich coiled-coil 2C | -0.03825 |
| RPL7 | ribosomal protein L7 | -0.0381937 |
| DSPP | dentin sialophosphoprotein | -0.0379702 |
| FAM13A | family with sequence similarity 13, member A | -0.0378832 |
| OPTN | optineurin | -0.0373952 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0373562 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0370602 |
| ASPH | aspartate beta-hydroxylase | -0.0370556 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0366152 |
| FNIP1 | folliculin interacting protein 1 | -0.0359594 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0359561 |
| CDCP1 | CUB domain containing protein 1 | -0.0355492 |
| MED13L | mediator complex subunit 13-like | -0.0349456 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.034392 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0341937 |
| INTS6 | integrator complex subunit 6 | -0.0341535 |
| RPLP1 | ribosomal protein, large, P1 | -0.0341041 |
| CCDC88A | coiled-coil domain containing 88A | -0.0339284 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0334858 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0333676 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.0331241 |
| ERBIN | erbb2 interacting protein | -0.0329743 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0326977 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.032486 |
| RPS12 | ribosomal protein S12 | -0.0324822 |
| TLN1 | talin 1 | -0.0322877 |
| RUNX1 | runt-related transcription factor 1 | -0.0321475 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0321298 |
| RPL11 | ribosomal protein L11 | -0.031986 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0319017 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0316667 |
| RPL12 | ribosomal protein L12 | -0.0316066 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -0.0315127 |
| MUC17 | mucin 17, cell surface associated | -0.0314621 |
| PMM2 | phosphomannomutase 2 | -0.0314561 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0313863 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0312709 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0308291 |
| UBC | ubiquitin C | -0.0307421 |
| RPL5 | ribosomal protein L5 | -0.0305893 |
