| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bisoprolol (hemifumarate) perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bisoprolol (hemifumarate)_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.209233 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | 0.122542 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.121381 |
| VCL | vinculin | 0.113708 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.111977 |
| COL5A2 | collagen, type V, alpha 2 | 0.0949993 |
| CADM2 | cell adhesion molecule 2 | 0.0906557 |
| ZNF608 | zinc finger protein 608 | 0.079338 |
| CDH18 | cadherin 18, type 2 | 0.0786391 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0762488 |
| RIGI | RNA sensor RIG-I | 0.076095 |
| TENM3 | teneurin transmembrane protein 3 | 0.074849 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0707432 |
| CENPF | centromere protein F, 350/400kDa | 0.0555756 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | 0.0533648 |
| MKI67 | marker of proliferation Ki-67 | 0.0512755 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0508057 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0491933 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | 0.0491726 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0470936 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.046921 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0458627 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0445683 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0444028 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0440613 |
| RAD51B | RAD51 paralog B | 0.0437942 |
| NFIA | nuclear factor I/A | 0.042895 |
| ZNF644 | zinc finger protein 644 | 0.0427171 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0421929 |
| VMP1 | vacuole membrane protein 1 | 0.0395326 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0383721 |
| JMJD1C | jumonji domain containing 1C | 0.0376719 |
| TOX | thymocyte selection-associated high mobility group box | 0.0356342 |
| SMAD2 | SMAD family member 2 | 0.0355261 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0351916 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0342337 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | 0.0339925 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0335625 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0333423 |
| NF1 | neurofibromin 1 | 0.0326685 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0323819 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0323691 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0319743 |
| H1-0 | H1.0 linker histone | 0.031375 |
| NFIB | nuclear factor I/B | 0.0313381 |
| ENO1 | enolase 1, (alpha) | 0.031145 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0309877 |
| ACTG1 | actin gamma 1 | 0.0309808 |
| RPL4 | ribosomal protein L4 | 0.0308202 |
| CDK12 | cyclin-dependent kinase 12 | 0.0307971 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0305902 |
| IGF2BP1 | insulin-like growth factor 2 mRNA binding protein 1 | 0.0305153 |
| RPS24 | ribosomal protein S24 | 0.0303399 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | 0.0302759 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0300711 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0300139 |
| FHIT | fragile histidine triad | 0.0294793 |
| RRM2 | ribonucleotide reductase M2 | 0.0287016 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0283676 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0278693 |
| CENPE | centromere protein E, 312kDa | 0.0275499 |
| SHROOM3 | shroom family member 3 | 0.0274735 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0274391 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | 0.0269868 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0268951 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0268675 |
| ATP11A | ATPase, class VI, type 11A | 0.0266923 |
| MED13 | mediator complex subunit 13 | 0.0266333 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0264766 |
| SMAD6 | SMAD family member 6 | 0.0264533 |
| TLK1 | tousled-like kinase 1 | 0.0264433 |
| TNPO3 | transportin 3 | 0.026424 |
| WWOX | WW domain containing oxidoreductase | 0.0262146 |
| RBBP6 | retinoblastoma binding protein 6 | 0.0262111 |
| POTEF | POTE ankyrin domain family, member F | 0.0260355 |
| FAT1 | FAT atypical cadherin 1 | 0.0259009 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0258556 |
| CARD18 | caspase recruitment domain family, member 18 | 0.0256401 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0255055 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0253681 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0253677 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0251359 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0250818 |
| NRG1 | neuregulin 1 | 0.0249751 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0249283 |
| AOPEP | aminopeptidase O (putative) | 0.0248646 |
| MTAP | methylthioadenosine phosphorylase | 0.0248629 |
| PHACTR4 | phosphatase and actin regulator 4 | 0.0248502 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0247658 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0246715 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | 0.0241207 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0240551 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0240007 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0238908 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0232811 |
| HMGB2 | high mobility group box 2 | 0.0232685 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0231409 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.0231293 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0229993 |
| FLNA | filamin A, alpha | 0.0227497 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.125985 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0943022 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0910092 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0907852 |
| PTMA | prothymosin, alpha | -0.0878946 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0722394 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | -0.0700035 |
| TMSB10 | thymosin beta 10 | -0.0672382 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0666384 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.060371 |
| RBM25 | RNA binding motif protein 25 | -0.0603602 |
| FTL | ferritin, light polypeptide | -0.0584497 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0569713 |
| RPS8 | ribosomal protein S8 | -0.052174 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.05196 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0516942 |
| CANX | calnexin | -0.0512139 |
| RPS19 | ribosomal protein S19 | -0.0505888 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0504432 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0489893 |
| RPS6 | ribosomal protein S6 | -0.0475721 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0470624 |
| NDRG1 | N-myc downstream regulated 1 | -0.0467745 |
| MT2A | metallothionein 2A | -0.0467295 |
| RPS3 | ribosomal protein S3 | -0.0453568 |
| RPL12 | ribosomal protein L12 | -0.0432468 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0415155 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0409046 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0394735 |
| NGLY1 | N-glycanase 1 | -0.0390773 |
| MXI1 | MAX interactor 1, dimerization protein | -0.038768 |
| WDR45B | WD repeat domain 45B | -0.0386153 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0379383 |
| RNF145 | ring finger protein 145 | -0.0365601 |
| EFNA5 | ephrin-A5 | -0.0359038 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0355763 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0354481 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0343082 |
| PCBP2 | poly(rC) binding protein 2 | -0.0336895 |
| NEBL | nebulette | -0.0325564 |
| RPL23 | ribosomal protein L23 | -0.0324051 |
| VIM | vimentin | -0.0322897 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0321683 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0321312 |
| RPL31 | ribosomal protein L31 | -0.0320409 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0314507 |
| RPLP1 | ribosomal protein, large, P1 | -0.0314219 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0312746 |
| RPL5 | ribosomal protein L5 | -0.0306965 |
| GOLGA4 | golgin A4 | -0.0304566 |
| FN1 | fibronectin 1 | -0.0304441 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0296199 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0295175 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0294543 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0293498 |
| RPS27 | ribosomal protein S27 | -0.0286911 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0286134 |
| RPL13A | ribosomal protein L13a | -0.0285575 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0279566 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0278888 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.027756 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0275285 |
| RPL34 | ribosomal protein L34 | -0.0273411 |
| RPL36 | ribosomal protein L36 | -0.0273384 |
| FNBP1L | formin binding protein 1-like | -0.0267151 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0262401 |
| SUN1 | Sad1 and UNC84 domain containing 1 | -0.025985 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0259759 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0258102 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.025516 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0249755 |
| S100A6 | S100 calcium binding protein A6 | -0.0249037 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0248158 |
| INSIG2 | insulin induced gene 2 | -0.0247932 |
| PHIP | pleckstrin homology domain interacting protein | -0.0247894 |
| FAM162A | family with sequence similarity 162, member A | -0.024704 |
| SOX2 | SRY (sex determining region Y)-box 2 | -0.0246172 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0245901 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.024301 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0241442 |
| USP37 | ubiquitin specific peptidase 37 | -0.0240603 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0240182 |
| RPL18 | ribosomal protein L18 | -0.0236366 |
| FOXO3 | forkhead box O3 | -0.0235258 |
| HLA-B | major histocompatibility complex, class I, B | -0.0234584 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0234388 |
| SEC24D | SEC24 family member D | -0.023343 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0233368 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0231536 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0228769 |
| KDM6B | lysine (K)-specific demethylase 6B | -0.0226316 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0225981 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0224247 |
| ZC3H13 | zinc finger CCCH-type containing 13 | -0.0223442 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0222944 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0220078 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0219356 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.02184 |
| RPL28 | ribosomal protein L28 | -0.0218317 |
| RPL37A | ribosomal protein L37a | -0.0217873 |
