| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bisoprolol (hemifumarate) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bisoprolol (hemifumarate)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VGF | VGF nerve growth factor inducible | 0.176228 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.129244 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.127328 |
| FN1 | fibronectin 1 | 0.120115 |
| GPC6 | glypican 6 | 0.106815 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.079393 |
| NLGN1 | neuroligin 1 | 0.0790213 |
| FMN1 | formin 1 | 0.0736117 |
| FRMD4A | FERM domain containing 4A | 0.0580202 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0520168 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0434852 |
| COL19A1 | collagen, type XIX, alpha 1 | 0.0424387 |
| PDE10A | phosphodiesterase 10A | 0.0410211 |
| TNNC1 | troponin C type 1 (slow) | 0.0391067 |
| PRELID2 | PRELI domain containing 2 | 0.0384575 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0354507 |
| NAV1 | neuron navigator 1 | 0.0353939 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0350054 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | 0.0348498 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0335598 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0313831 |
| NAV3 | neuron navigator 3 | 0.0309902 |
| PCDH7 | protocadherin 7 | 0.030656 |
| MACROD2 | MACRO domain containing 2 | 0.0304833 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0301748 |
| OXR1 | oxidation resistance 1 | 0.0290914 |
| DST | dystonin | 0.0280422 |
| EHBP1 | EH domain binding protein 1 | 0.0278416 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0276513 |
| ASPH | aspartate beta-hydroxylase | 0.0272643 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.027178 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0268788 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0268022 |
| CDK14 | cyclin-dependent kinase 14 | 0.0265853 |
| CTTNBP2 | cortactin binding protein 2 | 0.0255957 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | 0.024116 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0240442 |
| EXOC4 | exocyst complex component 4 | 0.0236783 |
| CUX1 | cut-like homeobox 1 | 0.0225451 |
| ATXN1 | ataxin 1 | 0.0224275 |
| RAD51B | RAD51 paralog B | 0.0223483 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0221715 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0216809 |
| NAV2 | neuron navigator 2 | 0.0215262 |
| SETBP1 | SET binding protein 1 | 0.0211004 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0210987 |
| AHNAK | AHNAK nucleoprotein | 0.0187067 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.018476 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.018343 |
| FHIT | fragile histidine triad | 0.0183041 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0180936 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0180622 |
| ZNF704 | zinc finger protein 704 | 0.0179576 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | 0.0179015 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0176724 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0176377 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0176081 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | 0.0174057 |
| SCFD2 | sec1 family domain containing 2 | 0.0172517 |
| NEGR1 | neuronal growth regulator 1 | 0.0170045 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0167892 |
| SEPTIN9 | septin 9 | 0.0165994 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0165876 |
| RUNX1 | runt-related transcription factor 1 | 0.0163752 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0162095 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0161883 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.01612 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0154781 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0151308 |
| ZSWIM5 | zinc finger, SWIM-type containing 5 | 0.0150649 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 0.0147705 |
| RFX7 | regulatory factor X, 7 | 0.0146536 |
| SMYD3 | SET and MYND domain containing 3 | 0.0145247 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0143806 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0143446 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0141352 |
| FGF13 | fibroblast growth factor 13 | 0.014033 |
| RNF213 | ring finger protein 213 | 0.0138566 |
| NHSL1 | NHS-like 1 | 0.0136864 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0134789 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.013363 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0132251 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | 0.0132069 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0131962 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0131624 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.01314 |
| GHR | growth hormone receptor | 0.0130977 |
| KIAA1549L | KIAA1549-like | 0.0130516 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0130265 |
| PKP4 | plakophilin 4 | 0.0129803 |
| PARVB | parvin, beta | 0.0129253 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0129075 |
| ALMS1 | Alstrom syndrome protein 1 | 0.0128504 |
| LSAMP | limbic system-associated membrane protein | 0.0128222 |
| CFAP20DC | CFAP20 domain containing | 0.0125033 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0124376 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0123837 |
| NRCAM | neuronal cell adhesion molecule | 0.0122821 |
| TULP4 | tubby like protein 4 | 0.012232 |
| STRIP2 | striatin interacting protein 2 | 0.0122146 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.262876 |
| NDRG1 | N-myc downstream regulated 1 | -0.134811 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.11106 |
| VIM | vimentin | -0.102429 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0959688 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0917895 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0898997 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0753807 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0645749 |
| MT2A | metallothionein 2A | -0.0596278 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0590543 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0563707 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0534109 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0517034 |
| CDC73 | cell division cycle 73 | -0.0512808 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0510246 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0508075 |
| ZNF292 | zinc finger protein 292 | -0.0463124 |
| NUP58 | nucleoporin 58 | -0.0449643 |
| RNF145 | ring finger protein 145 | -0.0427132 |
| FTL | ferritin, light polypeptide | -0.042169 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0417999 |
| COPA | coatomer protein complex, subunit alpha | -0.0414038 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0405204 |
| RYBP | RING1 and YY1 binding protein | -0.0402459 |
| COG5 | component of oligomeric golgi complex 5 | -0.0397476 |
| ANXA2 | annexin A2 | -0.0396134 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0390815 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0387254 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0385638 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0381247 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0379578 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0379026 |
| PTMA | prothymosin, alpha | -0.0378782 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0377244 |
| WDR45B | WD repeat domain 45B | -0.0374191 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0372703 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0359208 |
| EGR1 | early growth response 1 | -0.0354138 |
| RLF | rearranged L-myc fusion | -0.0352384 |
| TMSB10 | thymosin beta 10 | -0.0344691 |
| CALR | calreticulin | -0.0322709 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0315991 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0311813 |
| NPR2 | natriuretic peptide receptor 2 | -0.0311333 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.031053 |
| HELZ | helicase with zinc finger | -0.0309398 |
| CCNL1 | cyclin L1 | -0.0308695 |
| RHEB | Ras homolog enriched in brain | -0.03048 |
| ADM | adrenomedullin | -0.0296956 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0293076 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0276697 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0268657 |
| S100A6 | S100 calcium binding protein A6 | -0.0267546 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.026065 |
| FMNL2 | formin-like 2 | -0.0258546 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0257442 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0250747 |
| FOSL1 | FOS-like antigen 1 | -0.0250591 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.024963 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0246997 |
| INSIG2 | insulin induced gene 2 | -0.0242309 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0239198 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0238519 |
| PHF21A | PHD finger protein 21A | -0.0234757 |
| UBC | ubiquitin C | -0.0231704 |
| YBX1 | Y box binding protein 1 | -0.0231471 |
| RPLP1 | ribosomal protein, large, P1 | -0.0230607 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0230234 |
| SRPK2 | SRSF protein kinase 2 | -0.023009 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0227855 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.022329 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0222314 |
| SEC24A | SEC24 family member A | -0.0222306 |
| CD109 | CD109 molecule | -0.0219892 |
| RBM39 | RNA binding motif protein 39 | -0.0214406 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0213875 |
| GOLGA4 | golgin A4 | -0.0213286 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0212511 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | -0.0211362 |
| JUN | jun proto-oncogene | -0.0211136 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0210933 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0208633 |
| XPO1 | exportin 1 | -0.0208423 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0208189 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0206177 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0205231 |
| RPS19 | ribosomal protein S19 | -0.0204657 |
| SSBP3 | single stranded DNA binding protein 3 | -0.0201037 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0198504 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | -0.0196145 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0195662 |
| USP3 | ubiquitin specific peptidase 3 | -0.0191685 |
| RBM33 | RNA binding motif protein 33 | -0.0190586 |
| MEF2A | myocyte enhancer factor 2A | -0.0190272 |
| CABIN1 | calcineurin binding protein 1 | -0.0190116 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0189481 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0187329 |
| ARRDC3 | arrestin domain containing 3 | -0.0186534 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0185994 |
