| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bisoprolol (hemifumarate) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bisoprolol (hemifumarate)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.18297 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.14979 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.125414 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.10517 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.103147 |
| LOC112694756 | uncharaterized LOC112694756 | 0.085222 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.078042 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0773104 |
| PGK1 | phosphoglycerate kinase 1 | 0.0732119 |
| TMSB4X | thymosin beta 4, X-linked | 0.0729838 |
| AHNAK | AHNAK nucleoprotein | 0.0727512 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0706254 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0700723 |
| UBC | ubiquitin C | 0.0642216 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0632601 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0603065 |
| MMP7 | matrix metallopeptidase 7 | 0.0603015 |
| FAM13A | family with sequence similarity 13, member A | 0.0597931 |
| APP | amyloid beta (A4) precursor protein | 0.0595674 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0585449 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0579216 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0542343 |
| MT1X | metallothionein 1X | 0.0539371 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0537479 |
| H1-0 | H1.0 linker histone | 0.0511275 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0486708 |
| LAMB3 | laminin, beta 3 | 0.0475343 |
| FLNA | filamin A, alpha | 0.0456338 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0453217 |
| OGA | O-GlcNAcase | 0.0449737 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0439933 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0436835 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0436214 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.041698 |
| APOL1 | apolipoprotein L, 1 | 0.0408723 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0405267 |
| USP3 | ubiquitin specific peptidase 3 | 0.0394276 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0390035 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0387275 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0383073 |
| FAM162A | family with sequence similarity 162, member A | 0.0381882 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0376758 |
| RBM39 | RNA binding motif protein 39 | 0.0376553 |
| SMAD3 | SMAD family member 3 | 0.0372919 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0371892 |
| SPAG9 | sperm associated antigen 9 | 0.037087 |
| PLAU | plasminogen activator, urokinase | 0.0367418 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0362713 |
| NUP58 | nucleoporin 58 | 0.0362257 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0355174 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0353438 |
| WDR45B | WD repeat domain 45B | 0.0350142 |
| ZNF292 | zinc finger protein 292 | 0.0345698 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0341582 |
| TXNRD1 | thioredoxin reductase 1 | 0.0341252 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0341032 |
| TOP1 | topoisomerase (DNA) I | 0.0340944 |
| CANX | calnexin | 0.0339954 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0337092 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0335453 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0332698 |
| ENO1 | enolase 1, (alpha) | 0.0329123 |
| KLF6 | Kruppel-like factor 6 | 0.0325868 |
| TMEM123 | transmembrane protein 123 | 0.0320819 |
| RLF | rearranged L-myc fusion | 0.0316357 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0312225 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0310708 |
| TGM2 | transglutaminase 2 | 0.030873 |
| ABI1 | abl-interactor 1 | 0.0307675 |
| EZR | ezrin | 0.0307668 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0306576 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0306491 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0304536 |
| CD2AP | CD2-associated protein | 0.0302392 |
| RPL4 | ribosomal protein L4 | 0.0302274 |
| MYOF | myoferlin | 0.0299528 |
| FA2H | fatty acid 2-hydroxylase | 0.0294773 |
| KRT18 | keratin 18, type I | 0.0294664 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0292709 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0290967 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0290202 |
| MATR3 | matrin 3 | 0.0289635 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0287551 |
| RAP2B | RAP2B, member of RAS oncogene family | 0.0286645 |
| KRT8 | keratin 8, type II | 0.0286314 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0285732 |
| LAMC2 | laminin, gamma 2 | 0.0284443 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0282763 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0280011 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0276895 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0276264 |
| TUBB | tubulin, beta class I | 0.0273544 |
| HNF1B | HNF1 homeobox B | 0.0272916 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0268929 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0268462 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.026829 |
| CD47 | CD47 molecule | 0.0266953 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.0265485 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.026283 |
| LOX | lysyl oxidase | 0.0260102 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SAMD4A | sterile alpha motif domain containing 4A | -0.168446 |
| MT2A | metallothionein 2A | -0.154315 |
| TMSB10 | thymosin beta 10 | -0.104242 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0971826 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0892653 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0855957 |
| DTNA | dystrobrevin, alpha | -0.0712572 |
| NABP1 | nucleic acid binding protein 1 | -0.0653099 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0627364 |
| RAD51B | RAD51 paralog B | -0.0624443 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0552683 |
| INTS6 | integrator complex subunit 6 | -0.0547293 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0544827 |
| SP100 | SP100 nuclear antigen | -0.0533806 |
| EGR1 | early growth response 1 | -0.050089 |
| PRKCA | protein kinase C, alpha | -0.0487774 |
| RPL23 | ribosomal protein L23 | -0.0486363 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0480148 |
| RCOR1 | REST corepressor 1 | -0.0478013 |
| HDAC9 | histone deacetylase 9 | -0.0476742 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0470316 |
| FTL | ferritin, light polypeptide | -0.0463799 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0462421 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0461712 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0449825 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0442571 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0421997 |
| GOLGB1 | golgin B1 | -0.0401236 |
| RPL9 | ribosomal protein L9 | -0.0395009 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0394358 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0392589 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0391527 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0380844 |
| TJP1 | tight junction protein 1 | -0.0378365 |
| CMIP | c-Maf inducing protein | -0.0374508 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0369724 |
| ST8SIA6 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 | -0.0363315 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0362784 |
| EFNA5 | ephrin-A5 | -0.0362528 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0361602 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0361176 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0358074 |
| RASAL2 | RAS protein activator like 2 | -0.0354896 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0350906 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0345688 |
| RPS19 | ribosomal protein S19 | -0.0343013 |
| NRG3 | neuregulin 3 | -0.0342514 |
| MX1 | MX dynamin-like GTPase 1 | -0.0341225 |
| MT1E | metallothionein 1E | -0.0337371 |
| RPL37A | ribosomal protein L37a | -0.0329424 |
| HMGA2 | high mobility group AT-hook 2 | -0.0327417 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0326057 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0324165 |
| EGFR | epidermal growth factor receptor | -0.031439 |
| PCNX4 | pecanex 4 | -0.0312899 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0311479 |
| RPL31 | ribosomal protein L31 | -0.0304735 |
| RPS8 | ribosomal protein S8 | -0.0302491 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -0.0301422 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0299934 |
| PHF3 | PHD finger protein 3 | -0.0294993 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0289132 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0287739 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0285845 |
| B2M | beta-2-microglobulin | -0.0285301 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0280902 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0278131 |
| RPS3 | ribosomal protein S3 | -0.0272658 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0270027 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | -0.0268944 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0267985 |
| GPATCH2L | G patch domain containing 2-like | -0.026697 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0266116 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0265178 |
| MUC16 | mucin 16, cell surface associated | -0.0263862 |
| ADAM32 | ADAM metallopeptidase domain 32 | -0.026314 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0261779 |
| NRG1 | neuregulin 1 | -0.0260485 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0258239 |
| PARD3 | par-3 family cell polarity regulator | -0.0255411 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0252851 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0252604 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0252486 |
| USP34 | ubiquitin specific peptidase 34 | -0.0250099 |
| RUNX1 | runt-related transcription factor 1 | -0.0250007 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0249612 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0248872 |
| MYO1E | myosin IE | -0.0248339 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0247231 |
| FBXO11 | F-box protein 11 | -0.0244803 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0242673 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0241087 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0239384 |
| ARF4 | ADP-ribosylation factor 4 | -0.0239079 |
| RNF213 | ring finger protein 213 | -0.0238424 |
| HM13 | histocompatibility (minor) 13 | -0.0238224 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0237655 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0232552 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0232245 |
| FAM107B | family with sequence similarity 107, member B | -0.0231665 |
