| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bisoprolol (hemifumarate) perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bisoprolol (hemifumarate)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GATA3 | GATA binding protein 3 | 0.0631625 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0550589 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0472051 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0450522 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0419357 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0391417 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.036379 |
| GLG1 | golgi glycoprotein 1 | 0.0345053 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0340389 |
| ENAH | enabled homolog (Drosophila) | 0.0339204 |
| FOXO3 | forkhead box O3 | 0.0336469 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.031902 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0317171 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0312841 |
| RPL35A | ribosomal protein L35a | 0.030774 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0305776 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0304398 |
| FKBP1A | FK506 binding protein 1A, 12kDa | 0.0304127 |
| SIK3 | SIK family kinase 3 | 0.0299826 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0293101 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0292981 |
| SEC24B | SEC24 family member B | 0.0286354 |
| MEF2A | myocyte enhancer factor 2A | 0.0282043 |
| ZNF148 | zinc finger protein 148 | 0.0281951 |
| NFIB | nuclear factor I/B | 0.0281729 |
| JMJD1C | jumonji domain containing 1C | 0.0281074 |
| RAB3GAP2 | RAB3 GTPase activating protein subunit 2 (non-catalytic) | 0.0280813 |
| TMEM259 | transmembrane protein 259 | 0.0274518 |
| RPS23 | ribosomal protein S23 | 0.027049 |
| IGF2 | insulin-like growth factor 2 | 0.0269219 |
| QKI | QKI, KH domain containing, RNA binding | 0.026854 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0264474 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0262105 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0261818 |
| TGOLN2 | trans-golgi network protein 2 | 0.0260568 |
| ATXN2 | ataxin 2 | 0.0260499 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0259382 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.025904 |
| EZR | ezrin | 0.0258064 |
| FAM193A | family with sequence similarity 193, member A | 0.0256874 |
| TMED10 | transmembrane emp24-like trafficking protein 10 (yeast) | 0.0255144 |
| HACE1 | HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 | 0.0255017 |
| RBM20 | RNA binding motif protein 20 | 0.0254745 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0254589 |
| KDM5A | lysine (K)-specific demethylase 5A | 0.0252808 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0252776 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.024899 |
| TAPBP | TAP binding protein (tapasin) | 0.0246616 |
| PHKB | phosphorylase kinase, beta | 0.0244774 |
| RNF145 | ring finger protein 145 | 0.0243376 |
| RUNX1 | runt-related transcription factor 1 | 0.0242069 |
| PKM | pyruvate kinase, muscle | 0.0241459 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0238918 |
| RHOA | ras homolog family member A | 0.023873 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0235673 |
| CHN1 | chimerin 1 | 0.0235053 |
| GNG2 | guanine nucleotide binding protein (G protein), gamma 2 | 0.0234456 |
| TFG | TRK-fused gene | 0.0233028 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0232442 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | 0.0231827 |
| CEP170 | centrosomal protein 170kDa | 0.023106 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.023013 |
| PBRM1 | polybromo 1 | 0.022544 |
| ARHGAP10 | Rho GTPase activating protein 10 | 0.0223164 |
| ZNF292 | zinc finger protein 292 | 0.0222556 |
| RBM27 | RNA binding motif protein 27 | 0.022203 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0221281 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0218771 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0217987 |
| RAD51B | RAD51 paralog B | 0.0217644 |
| RPL3 | ribosomal protein L3 | 0.0216364 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0215441 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0214675 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0212006 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0210874 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0210814 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0209557 |
| CXXC5 | CXXC finger protein 5 | 0.0208972 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0208829 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.0204978 |
| SOX11 | SRY (sex determining region Y)-box 11 | 0.02047 |
| PHF14 | PHD finger protein 14 | 0.0204148 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0204108 |
| CDK8 | cyclin-dependent kinase 8 | 0.0204076 |
| RPS15 | ribosomal protein S15 | 0.0202184 |
| PCDH9 | protocadherin 9 | 0.0201685 |
| ATP5MG | ATP synthase membrane subunit g | 0.0200952 |
| NBAS | neuroblastoma amplified sequence | 0.0199284 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0198678 |
| ZRANB2 | zinc finger, RAN-binding domain containing 2 | 0.0198259 |
| EIF4E | eukaryotic translation initiation factor 4E | 0.0197112 |
| PFN1 | profilin 1 | 0.0196351 |
| TP53BP1 | tumor protein p53 binding protein 1 | 0.0194682 |
| USP8 | ubiquitin specific peptidase 8 | 0.0194663 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 0.0194548 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0194225 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0194027 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0193677 |
| GLI3 | GLI family zinc finger 3 | 0.0193279 |
| FBXO28 | F-box protein 28 | 0.0190339 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.198166 |
| FMN1 | formin 1 | -0.144028 |
| NRG1 | neuregulin 1 | -0.132219 |
| PTMA | prothymosin, alpha | -0.123806 |
| FAM13A | family with sequence similarity 13, member A | -0.0780641 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0748188 |
| RPL34 | ribosomal protein L34 | -0.0738251 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0695391 |
| FTL | ferritin, light polypeptide | -0.0689738 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.066961 |
| NDRG1 | N-myc downstream regulated 1 | -0.0651565 |
| RPLP1 | ribosomal protein, large, P1 | -0.0635506 |
| TRIB2 | tribbles pseudokinase 2 | -0.0632525 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0627325 |
| RPL23 | ribosomal protein L23 | -0.0624767 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0623802 |
| COL3A1 | collagen, type III, alpha 1 | -0.0574206 |
| SEPTIN2 | septin 2 | -0.0552955 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0542611 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0514848 |
| VCL | vinculin | -0.0511719 |
| ACTG1 | actin gamma 1 | -0.0494381 |
| RPL26 | ribosomal protein L26 | -0.0487634 |
| SYT1 | synaptotagmin I | -0.04789 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0476971 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0471215 |
| VIM | vimentin | -0.0459474 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0454382 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0453778 |
| SEPTIN9 | septin 9 | -0.0451838 |
| LMNA | lamin A/C | -0.0451344 |
| TMSB10 | thymosin beta 10 | -0.045085 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0445845 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0437596 |
| COL1A1 | collagen, type I, alpha 1 | -0.0436531 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0433621 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0432164 |
| RACK1 | receptor for activated C kinase 1 | -0.0429497 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0428452 |
| MSI2 | musashi RNA-binding protein 2 | -0.0417146 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0416012 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0408101 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0407847 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0405032 |
| RPS27A | ribosomal protein S27a | -0.040006 |
| CANX | calnexin | -0.0394049 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0390968 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.039074 |
| PCBP3 | poly(rC) binding protein 3 | -0.0389564 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.038349 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0380442 |
| STC1 | stanniocalcin 1 | -0.0378602 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0369575 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.036663 |
| H3-3B | H3.3 histone B | -0.0363381 |
| LPIN1 | lipin 1 | -0.0362784 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0357522 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0352139 |
| NCOR1 | nuclear receptor corepressor 1 | -0.035096 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.034796 |
| TCERG1 | transcription elongation regulator 1 | -0.0346675 |
| LDHA | lactate dehydrogenase A | -0.0345711 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0342106 |
| SQSTM1 | sequestosome 1 | -0.0341148 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0340652 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0339519 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0339196 |
| CFDP1 | craniofacial development protein 1 | -0.033818 |
| RPL5 | ribosomal protein L5 | -0.033796 |
| SP100 | SP100 nuclear antigen | -0.0335241 |
| ENO1 | enolase 1, (alpha) | -0.0329226 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0329179 |
| RPL9 | ribosomal protein L9 | -0.0318362 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0317228 |
| GPC5 | glypican 5 | -0.0314541 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0313433 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0313039 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0305275 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | -0.0305131 |
| FRMD4A | FERM domain containing 4A | -0.0303544 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.030327 |
| TPM4 | tropomyosin 4 | -0.0302937 |
| RPS24 | ribosomal protein S24 | -0.0302644 |
| FN1 | fibronectin 1 | -0.0302106 |
| RPL11 | ribosomal protein L11 | -0.0302062 |
| TCF12 | transcription factor 12 | -0.0299186 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0295716 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0294613 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0293752 |
| ASPH | aspartate beta-hydroxylase | -0.0292847 |
| SMYD3 | SET and MYND domain containing 3 | -0.0292497 |
| PHF3 | PHD finger protein 3 | -0.0292435 |
| RPS8 | ribosomal protein S8 | -0.0291614 |
| CRH | corticotropin releasing hormone | -0.0290453 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0288708 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0287898 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0287342 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0285779 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0285429 |
| BLTP3B | bridge-like lipid transfer protein family member 3B | -0.0285201 |
