| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bisoprolol (hemifumarate) perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bisoprolol (hemifumarate)_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.133648 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.120243 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.107665 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.096705 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0860178 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0814175 |
| TXNIP | thioredoxin interacting protein | 0.0704477 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.069596 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.061109 |
| LCN2 | lipocalin 2 | 0.0586862 |
| RUNX1 | runt-related transcription factor 1 | 0.0573027 |
| H1-0 | H1.0 linker histone | 0.0559506 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0540659 |
| ATP11A | ATPase, class VI, type 11A | 0.0539775 |
| SP100 | SP100 nuclear antigen | 0.0538404 |
| RNF213 | ring finger protein 213 | 0.0525378 |
| EPHB2 | EPH receptor B2 | 0.0522697 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0504882 |
| ATXN1 | ataxin 1 | 0.0488909 |
| TMEM62 | transmembrane protein 62 | 0.0482908 |
| NCKAP5 | NCK-associated protein 5 | 0.0479658 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0471404 |
| MAP7 | microtubule-associated protein 7 | 0.0469637 |
| FOXP1 | forkhead box P1 | 0.0468938 |
| MX2 | MX dynamin-like GTPase 2 | 0.046803 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0445439 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.044239 |
| XAF1 | XIAP associated factor 1 | 0.0422762 |
| RNF43 | ring finger protein 43 | 0.0421745 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0418257 |
| SPATA13 | spermatogenesis associated 13 | 0.0409102 |
| LYZ | lysozyme | 0.0408019 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0405666 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0386302 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0382884 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0373724 |
| PRKCA | protein kinase C, alpha | 0.0373183 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0371733 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0368406 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0367028 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0365468 |
| STK24 | serine/threonine kinase 24 | 0.0365217 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0363262 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0360696 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0358909 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0356494 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0347875 |
| RAD51B | RAD51 paralog B | 0.0346098 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0343705 |
| NF1 | neurofibromin 1 | 0.0333834 |
| PMP22 | peripheral myelin protein 22 | 0.0333739 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0332473 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | 0.0323174 |
| ADAR | adenosine deaminase, RNA-specific | 0.0320687 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0315392 |
| CD46 | CD46 molecule, complement regulatory protein | 0.031317 |
| OARD1 | O-acyl-ADP-ribose deacylase 1 | 0.0311549 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0308604 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0308095 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0308074 |
| IFNGR1 | interferon gamma receptor 1 | 0.030735 |
| MYO10 | myosin X | 0.0305277 |
| MED13L | mediator complex subunit 13-like | 0.0301841 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0295167 |
| FMN1 | formin 1 | 0.0291875 |
| TRERF1 | transcriptional regulating factor 1 | 0.0289513 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0286325 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0284641 |
| ITGA1 | integrin, alpha 1 | 0.028235 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0281022 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.028009 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0275205 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0274185 |
| CDC42SE2 | CDC42 small effector 2 | 0.0273198 |
| RIGI | RNA sensor RIG-I | 0.0273072 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0272864 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.027184 |
| PRELID2 | PRELI domain containing 2 | 0.0269704 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0268841 |
| MED13 | mediator complex subunit 13 | 0.0265422 |
| KIAA1217 | KIAA1217 | 0.026151 |
| CD2AP | CD2-associated protein | 0.0261252 |
| APP | amyloid beta (A4) precursor protein | 0.0258536 |
| UBAC2 | UBA domain containing 2 | 0.0257856 |
| ITGA6 | integrin, alpha 6 | 0.0257528 |
| VCL | vinculin | 0.0257052 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0256908 |
| MSI2 | musashi RNA-binding protein 2 | 0.025539 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 0.0254794 |
| ACTN4 | actinin, alpha 4 | 0.0254769 |
| SSH2 | slingshot protein phosphatase 2 | 0.0252155 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0251548 |
| HDAC4 | histone deacetylase 4 | 0.0248711 |
| EHBP1 | EH domain binding protein 1 | 0.0246903 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.02458 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0245169 |
| PTK2 | protein tyrosine kinase 2 | 0.0244757 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0244565 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0244308 |
| SYT1 | synaptotagmin I | 0.0242184 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | -0.166474 |
| EGR1 | early growth response 1 | -0.11736 |
| AREG | amphiregulin | -0.0815369 |
| ANXA2 | annexin A2 | -0.0799484 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0709127 |
| EZR | ezrin | -0.0681907 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0576085 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0563668 |
| B2M | beta-2-microglobulin | -0.0527035 |
| NDRG1 | N-myc downstream regulated 1 | -0.0526208 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.051273 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0489646 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0477812 |
| ERBIN | erbb2 interacting protein | -0.0476239 |
| INTS6 | integrator complex subunit 6 | -0.0422647 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0383517 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0379474 |
| EFNB2 | ephrin-B2 | -0.0376482 |
| SQSTM1 | sequestosome 1 | -0.0374363 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.037106 |
| MT2A | metallothionein 2A | -0.036769 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0356071 |
| MYO1E | myosin IE | -0.0346994 |
| CSTB | cystatin B (stefin B) | -0.0333269 |
| CLDN4 | claudin 4 | -0.033144 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0327877 |
| FTL | ferritin, light polypeptide | -0.0325643 |
| CCNL1 | cyclin L1 | -0.0322265 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0316635 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0301078 |
| SEC24A | SEC24 family member A | -0.0297982 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0295442 |
| HM13 | histocompatibility (minor) 13 | -0.029249 |
| SPAG9 | sperm associated antigen 9 | -0.029016 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0288394 |
| ARF4 | ADP-ribosylation factor 4 | -0.0288024 |
| MCL1 | myeloid cell leukemia 1 | -0.0287106 |
| ANXA1 | annexin A1 | -0.0284144 |
| PERP | PERP, TP53 apoptosis effector | -0.0281355 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.0280346 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0274764 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0273858 |
| HKDC1 | hexokinase domain containing 1 | -0.0271964 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0262579 |
| ADM | adrenomedullin | -0.0262158 |
| GOLGA4 | golgin A4 | -0.0261018 |
| TMSB10 | thymosin beta 10 | -0.0251626 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0251155 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0249237 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0248025 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0243142 |
| SDCBP | syndecan binding protein (syntenin) | -0.0242998 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.024111 |
| NABP1 | nucleic acid binding protein 1 | -0.023893 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0238324 |
| RPS3 | ribosomal protein S3 | -0.0236599 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.02365 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0235195 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0231996 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.022982 |
| JUN | jun proto-oncogene | -0.0228623 |
| IRF1 | interferon regulatory factor 1 | -0.0227737 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0227376 |
| TJP1 | tight junction protein 1 | -0.0223344 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.022217 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0221858 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0218989 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.021483 |
| CDHR2 | cadherin-related family member 2 | -0.0212731 |
| POTEF | POTE ankyrin domain family, member F | -0.0210915 |
| VIM | vimentin | -0.0209798 |
| ZNF165 | zinc finger protein 165 | -0.0208641 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.0207836 |
| MORF4L2 | mortality factor 4 like 2 | -0.020605 |
| RPLP1 | ribosomal protein, large, P1 | -0.0204211 |
| RND3 | Rho family GTPase 3 | -0.0203928 |
| CALU | calumenin | -0.0203418 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0202779 |
| RPL37A | ribosomal protein L37a | -0.0201667 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0200164 |
| LMNA | lamin A/C | -0.0197693 |
| ACTG1 | actin gamma 1 | -0.0195107 |
| GK | glycerol kinase | -0.0194822 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.019386 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0192525 |
| RAB5A | RAB5A, member RAS oncogene family | -0.019237 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0190022 |
| RPL34 | ribosomal protein L34 | -0.0188166 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0188156 |
| PRSS22 | protease, serine, 22 | -0.0187379 |
| RPS6 | ribosomal protein S6 | -0.018563 |
| KRT23 | keratin 23, type I | -0.018449 |
| LDHA | lactate dehydrogenase A | -0.0184239 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0183816 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0182663 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | -0.0182358 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0178076 |
| KIF16B | kinesin family member 16B | -0.0177524 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0177203 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.0177117 |
