| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bisoprolol (hemifumarate) perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bisoprolol (hemifumarate)_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.11889 |
| COL6A3 | collagen, type VI, alpha 3 | 0.102279 |
| MT2A | metallothionein 2A | 0.0861636 |
| MT1X | metallothionein 1X | 0.0808975 |
| ASPH | aspartate beta-hydroxylase | 0.0648838 |
| AHNAK | AHNAK nucleoprotein | 0.0570053 |
| EXT1 | exostosin glycosyltransferase 1 | 0.053004 |
| RPLP2 | ribosomal protein, large, P2 | 0.0509768 |
| OSMR | oncostatin M receptor | 0.045079 |
| STC1 | stanniocalcin 1 | 0.04498 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.04337 |
| TNNC1 | troponin C type 1 (slow) | 0.042797 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0403337 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0364435 |
| RPS24 | ribosomal protein S24 | 0.0355 |
| LOC112694756 | uncharaterized LOC112694756 | 0.032231 |
| CALN1 | calneuron 1 | 0.0314284 |
| RPS23 | ribosomal protein S23 | 0.0311829 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0305561 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0303354 |
| FLNA | filamin A, alpha | 0.0284831 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0266315 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0263626 |
| LOX | lysyl oxidase | 0.0256732 |
| ACTN1 | actinin, alpha 1 | 0.0255255 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0254804 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0253858 |
| RPL32 | ribosomal protein L32 | 0.0252957 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0251422 |
| RPL38 | ribosomal protein L38 | 0.0248709 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0244611 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0244439 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0244124 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0242405 |
| ENO1 | enolase 1, (alpha) | 0.0242301 |
| TPTE | transmembrane phosphatase with tensin homology | 0.0241769 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0241143 |
| RPS13 | ribosomal protein S13 | 0.0237443 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0236807 |
| BPTF | bromodomain PHD finger transcription factor | 0.0235328 |
| RRBP1 | ribosome binding protein 1 | 0.0234003 |
| SEPTIN10 | septin 10 | 0.023163 |
| ACTN4 | actinin, alpha 4 | 0.0230798 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0229856 |
| EMP1 | epithelial membrane protein 1 | 0.0227415 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0227197 |
| SDC4 | syndecan 4 | 0.0226161 |
| RPL7A | ribosomal protein L7a | 0.021954 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.0215965 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0214478 |
| LMNA | lamin A/C | 0.0212967 |
| PMM2 | phosphomannomutase 2 | 0.0212079 |
| SEPTIN9 | septin 9 | 0.021058 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0210253 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0209208 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0207659 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0207239 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0207207 |
| HDLBP | high density lipoprotein binding protein | 0.0205209 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0204797 |
| CANX | calnexin | 0.020301 |
| SMYD3 | SET and MYND domain containing 3 | 0.0201578 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.0200084 |
| TXNIP | thioredoxin interacting protein | 0.0198593 |
| SMAD3 | SMAD family member 3 | 0.0197344 |
| CFAP96 | cilia and flagella associated protein 96 | 0.0196419 |
| GANAB | glucosidase, alpha; neutral AB | 0.0193068 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.0191082 |
| TMEM263 | transmembrane protein 263 | 0.0190627 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0189802 |
| VGF | VGF nerve growth factor inducible | 0.0188117 |
| FAM20C | family with sequence similarity 20, member C | 0.0185476 |
| ARCN1 | archain 1 | 0.0185352 |
| NAV2 | neuron navigator 2 | 0.0185023 |
| RPL35A | ribosomal protein L35a | 0.0184029 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0183243 |
| RPL28 | ribosomal protein L28 | 0.0181815 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0180754 |
| DUSP6 | dual specificity phosphatase 6 | 0.0180383 |
| RUNX1 | runt-related transcription factor 1 | 0.0179355 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.017893 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | 0.0178449 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0177995 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.0177533 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0176751 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0176741 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0175857 |
| RPS11 | ribosomal protein S11 | 0.0175791 |
| CCND2 | cyclin D2 | 0.0174698 |
| FLNB | filamin B, beta | 0.0174025 |
| RPS29 | ribosomal protein S29 | 0.0173636 |
| PDXK | pyridoxal (pyridoxine, vitamin B6) kinase | 0.0171699 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0168198 |
| ATXN1 | ataxin 1 | 0.0167873 |
| ARF1 | ADP-ribosylation factor 1 | 0.0166739 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0166516 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.0163954 |
| GOLGA3 | golgin A3 | 0.0163074 |
| NSRP1 | nuclear speckle splicing regulatory protein 1 | 0.0162183 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0161674 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.209057 |
| TMSB10 | thymosin beta 10 | -0.103077 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0907822 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.076897 |
| FAM13A | family with sequence similarity 13, member A | -0.0629151 |
| NDRG1 | N-myc downstream regulated 1 | -0.0619293 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0616349 |
| CADM1 | cell adhesion molecule 1 | -0.0615061 |
| FTL | ferritin, light polypeptide | -0.0608963 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0604028 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0592927 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0589425 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0578249 |
| B2M | beta-2-microglobulin | -0.0550995 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.054631 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0539295 |
| ADM | adrenomedullin | -0.0517064 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0503018 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0498036 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0482965 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0482408 |
| SMC4 | structural maintenance of chromosomes 4 | -0.044569 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0441082 |
| SPAG9 | sperm associated antigen 9 | -0.0435445 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0434404 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0433787 |
| GNAS | GNAS complex locus | -0.043315 |
| SETD5 | SET domain containing 5 | -0.0429983 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0425449 |
| USP3 | ubiquitin specific peptidase 3 | -0.0418825 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0415292 |
| PTMA | prothymosin, alpha | -0.0411153 |
| RPL37A | ribosomal protein L37a | -0.0409198 |
| PCBP2 | poly(rC) binding protein 2 | -0.0407622 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0406008 |
| RTN4 | reticulon 4 | -0.0399966 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0390883 |
| HELZ | helicase with zinc finger | -0.0382953 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0380242 |
| RNF145 | ring finger protein 145 | -0.0373909 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0369772 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0369735 |
| POTEF | POTE ankyrin domain family, member F | -0.0360321 |
| RLF | rearranged L-myc fusion | -0.0353018 |
| NOP58 | NOP58 ribonucleoprotein | -0.035266 |
| ANLN | anillin, actin binding protein | -0.0349309 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0344742 |
| VEGFA | vascular endothelial growth factor A | -0.0344444 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0343517 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0340322 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0334453 |
| DEPP1 | DEPP autophagy regulator 1 | -0.0333389 |
| MATR3 | matrin 3 | -0.0333258 |
| YBX1 | Y box binding protein 1 | -0.0331624 |
| RPS8 | ribosomal protein S8 | -0.0331613 |
| JMJD1C | jumonji domain containing 1C | -0.0329848 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0329281 |
| TPI1 | triosephosphate isomerase 1 | -0.0328305 |
| SET | SET nuclear proto-oncogene | -0.0326856 |
| RBM39 | RNA binding motif protein 39 | -0.032303 |
| FOSL1 | FOS-like antigen 1 | -0.0315755 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0315389 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | -0.0313736 |
| SEPTIN7 | septin 7 | -0.0311865 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0308367 |
| CCNL1 | cyclin L1 | -0.0308072 |
| NUP58 | nucleoporin 58 | -0.0307258 |
| ANXA5 | annexin A5 | -0.0306435 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0301979 |
| ZNF395 | zinc finger protein 395 | -0.0298157 |
| HMGA1 | high mobility group AT-hook 1 | -0.0297993 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0296903 |
| COLEC11 | collectin sub-family member 11 | -0.029205 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0291816 |
| BBX | bobby sox homolog (Drosophila) | -0.0289512 |
| MAP1B | microtubule-associated protein 1B | -0.0288106 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0286464 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0285103 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0281729 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0279466 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0278102 |
| RELCH | RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing | -0.0277299 |
| GDF15 | growth differentiation factor 15 | -0.0273872 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0273244 |
| COPA | coatomer protein complex, subunit alpha | -0.0272655 |
| TPM3 | tropomyosin 3 | -0.0271082 |
| SRP54 | signal recognition particle 54kDa | -0.0270365 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0269284 |
| CENPF | centromere protein F, 350/400kDa | -0.026688 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0266077 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0263035 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0261088 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0260935 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0260341 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | -0.0260337 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0260217 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0260042 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0260042 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0258193 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0257826 |
