| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bisoprolol (hemifumarate) perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bisoprolol (hemifumarate)_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.129339 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0714371 |
| FAT1 | FAT atypical cadherin 1 | 0.0593107 |
| SETD5 | SET domain containing 5 | 0.0557506 |
| HM13 | histocompatibility (minor) 13 | 0.0553374 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0470658 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0443312 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0440038 |
| COPA | coatomer protein complex, subunit alpha | 0.0436655 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0429904 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.042076 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.041619 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0415437 |
| RUNX1 | runt-related transcription factor 1 | 0.0405831 |
| SRP54 | signal recognition particle 54kDa | 0.0392637 |
| ZNF638 | zinc finger protein 638 | 0.0382844 |
| PHF21A | PHD finger protein 21A | 0.0382104 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0380696 |
| YEATS2 | YEATS domain containing 2 | 0.0374206 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0366071 |
| PCBP2 | poly(rC) binding protein 2 | 0.0365963 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0363936 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0361172 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0360186 |
| SCARB1 | scavenger receptor class B, member 1 | 0.0356952 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0355577 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0353694 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0350647 |
| CUX1 | cut-like homeobox 1 | 0.0349758 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0347942 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0345932 |
| CMIP | c-Maf inducing protein | 0.0343284 |
| NDRG1 | N-myc downstream regulated 1 | 0.0342656 |
| GOSR2 | golgi SNAP receptor complex member 2 | 0.0338847 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.033553 |
| FOXO3 | forkhead box O3 | 0.0335259 |
| ZNF609 | zinc finger protein 609 | 0.0333052 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0325414 |
| BPTF | bromodomain PHD finger transcription factor | 0.0324823 |
| POTEF | POTE ankyrin domain family, member F | 0.032013 |
| LARP1B | La ribonucleoprotein domain family, member 1B | 0.0319229 |
| MORF4L2 | mortality factor 4 like 2 | 0.0319013 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0316151 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0315881 |
| LSR | lipolysis stimulated lipoprotein receptor | 0.0313148 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0310113 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0308405 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0305111 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0304982 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0304614 |
| CFAP96 | cilia and flagella associated protein 96 | 0.0304143 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0304072 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0302521 |
| SDC4 | syndecan 4 | 0.0301441 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0298983 |
| DIAPH1 | diaphanous-related formin 1 | 0.0296268 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0295042 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0289059 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.028811 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0283225 |
| YARS1 | tyrosyl-tRNA synthetase 1 | 0.0282978 |
| PHACTR4 | phosphatase and actin regulator 4 | 0.0281886 |
| FLNB | filamin B, beta | 0.0281067 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0280115 |
| PDS5B | PDS5 cohesin associated factor B | 0.0277765 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0277586 |
| MCL1 | myeloid cell leukemia 1 | 0.0276927 |
| EZR | ezrin | 0.027574 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0272069 |
| SEPTIN9 | septin 9 | 0.027106 |
| ZC3H15 | zinc finger CCCH-type containing 15 | 0.0270925 |
| GPBP1L1 | GC-rich promoter binding protein 1-like 1 | 0.027052 |
| EPB41 | erythrocyte membrane protein band 4.1 | 0.026938 |
| MED15 | mediator complex subunit 15 | 0.0267703 |
| EGR1 | early growth response 1 | 0.0266426 |
| KIF5B | kinesin family member 5B | 0.0263462 |
| PGM3 | phosphoglucomutase 3 | 0.02632 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0263156 |
| CDK13 | cyclin-dependent kinase 13 | 0.0262213 |
| RLF | rearranged L-myc fusion | 0.0261529 |
| NUP58 | nucleoporin 58 | 0.0260352 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0260026 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0259246 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0258383 |
| SAFB2 | scaffold attachment factor B2 | 0.0257289 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | 0.0256124 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0255833 |
| KLC1 | kinesin light chain 1 | 0.0255262 |
| WWOX | WW domain containing oxidoreductase | 0.0254757 |
| PREPL | prolyl endopeptidase-like | 0.0253962 |
| APP | amyloid beta (A4) precursor protein | 0.0253336 |
| TESK2 | testis-specific kinase 2 | 0.0251617 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0250465 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | 0.0250282 |
| DIAPH2 | diaphanous-related formin 2 | 0.0249656 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0248941 |
| UBAP1 | ubiquitin associated protein 1 | 0.0248068 |
| FAM193A | family with sequence similarity 193, member A | 0.024677 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0246594 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0246327 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.315497 |
| PTMA | prothymosin, alpha | -0.117884 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0944995 |
| AHNAK | AHNAK nucleoprotein | -0.0934901 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0702599 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0691494 |
| RPL35A | ribosomal protein L35a | -0.0606639 |
| RPL12 | ribosomal protein L12 | -0.0601629 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0578979 |
| OGA | O-GlcNAcase | -0.0573328 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0565872 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.055223 |
| RPS24 | ribosomal protein S24 | -0.053313 |
| RPS19 | ribosomal protein S19 | -0.0529883 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0500376 |
| BBX | bobby sox homolog (Drosophila) | -0.0444682 |
| RPL23 | ribosomal protein L23 | -0.042162 |
| TMSB10 | thymosin beta 10 | -0.0412126 |
| PGK1 | phosphoglycerate kinase 1 | -0.0381426 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0379088 |
| RPS21 | ribosomal protein S21 | -0.0359154 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0355316 |
| PRELID2 | PRELI domain containing 2 | -0.0351928 |
| RPL11 | ribosomal protein L11 | -0.0346653 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0345095 |
| RPS27A | ribosomal protein S27a | -0.0341961 |
| NSD3 | nuclear receptor binding SET domain protein 3 | -0.0341447 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0333021 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0329025 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0324413 |
| ENO1 | enolase 1, (alpha) | -0.0320963 |
| S100A9 | S100 calcium binding protein A9 | -0.031548 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.03131 |
| RPS25 | ribosomal protein S25 | -0.0306617 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0305826 |
| TMEM263 | transmembrane protein 263 | -0.0303545 |
| EPCAM | epithelial cell adhesion molecule | -0.0297866 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0296741 |
| WDR45B | WD repeat domain 45B | -0.0295058 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | -0.0293996 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0291239 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.029007 |
| COG6 | component of oligomeric golgi complex 6 | -0.0286666 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -0.0284167 |
| RPS13 | ribosomal protein S13 | -0.0282982 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0280698 |
| ANLN | anillin, actin binding protein | -0.0279482 |
| RRBP1 | ribosome binding protein 1 | -0.0276854 |
| FN1 | fibronectin 1 | -0.0275087 |
| KRT19 | keratin 19, type I | -0.0269635 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0269176 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0266651 |
| MED13L | mediator complex subunit 13-like | -0.0265625 |
| RPL8 | ribosomal protein L8 | -0.0265456 |
| MYL12B | myosin, light chain 12B, regulatory | -0.026477 |
| KRT18 | keratin 18, type I | -0.0261597 |
| RPL34 | ribosomal protein L34 | -0.0259147 |
| KRT8 | keratin 8, type II | -0.0258824 |
| RPLP1 | ribosomal protein, large, P1 | -0.0256685 |
| USP3 | ubiquitin specific peptidase 3 | -0.0256593 |
| HMGB1 | high mobility group box 1 | -0.0252934 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0249712 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.0249627 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0247419 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0246385 |
| SEPTIN10 | septin 10 | -0.0244741 |
| POU2F1 | POU class 2 homeobox 1 | -0.0244236 |
| LTN1 | listerin E3 ubiquitin protein ligase 1 | -0.0241455 |
| DSG2 | desmoglein 2 | -0.0240175 |
| CBX3 | chromobox homolog 3 | -0.0236488 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0236484 |
| CPNE3 | copine III | -0.0233739 |
| CCDC6 | coiled-coil domain containing 6 | -0.0232725 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0232219 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0230704 |
| INSIG2 | insulin induced gene 2 | -0.0229446 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | -0.0228962 |
| H2AZ1 | H2A.Z variant histone 1 | -0.0228175 |
| NF1 | neurofibromin 1 | -0.0228168 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0227937 |
| QKI | QKI, KH domain containing, RNA binding | -0.0227632 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | -0.0226864 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0226805 |
| TLK1 | tousled-like kinase 1 | -0.0226577 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | -0.0226056 |
| LMO7 | LIM domain 7 | -0.0224629 |
| TXNIP | thioredoxin interacting protein | -0.022377 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | -0.0223274 |
| H1-0 | H1.0 linker histone | -0.0221948 |
| GPR75-ASB3 | GPR75-ASB3 readthrough | -0.0221627 |
| CCSER2 | coiled-coil serine-rich protein 2 | -0.0220892 |
| SEPTIN7 | septin 7 | -0.0220319 |
| RPL31 | ribosomal protein L31 | -0.021994 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0217431 |
| RTN3 | reticulon 3 | -0.0216409 |
| CDC27 | cell division cycle 27 | -0.0216175 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0215792 |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | -0.0212783 |
| IGF2 | insulin-like growth factor 2 | -0.0212644 |
| TPD52 | tumor protein D52 | -0.0212472 |
