| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bisoprolol (hemifumarate) perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bisoprolol (hemifumarate)_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.137095 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0465711 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0277293 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0274179 |
| FLNA | filamin A, alpha | 0.0266766 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0243679 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0235526 |
| SMAD3 | SMAD family member 3 | 0.0231642 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0221456 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.022008 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0201947 |
| AXL | AXL receptor tyrosine kinase | 0.0194191 |
| ACTN4 | actinin, alpha 4 | 0.018489 |
| PKM | pyruvate kinase, muscle | 0.0184683 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0184616 |
| NDRG1 | N-myc downstream regulated 1 | 0.0180137 |
| DOT1L | DOT1-like histone H3K79 methyltransferase | 0.0160045 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0159653 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.015654 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0155247 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0153939 |
| RRM2 | ribonucleotide reductase M2 | 0.0147849 |
| SEPTIN9 | septin 9 | 0.0144267 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0140134 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0139314 |
| MT2A | metallothionein 2A | 0.0137079 |
| NECTIN2 | nectin cell adhesion molecule 2 | 0.0135951 |
| NPTN | neuroplastin | 0.0134686 |
| NUP58 | nucleoporin 58 | 0.0133832 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0128528 |
| MSN | moesin | 0.0120705 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0118758 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0118328 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0117569 |
| PER1 | period circadian clock 1 | 0.011607 |
| FOSL1 | FOS-like antigen 1 | 0.0114527 |
| USP3 | ubiquitin specific peptidase 3 | 0.0113925 |
| FOSL2 | FOS-like antigen 2 | 0.0113721 |
| CD82 | CD82 molecule | 0.011266 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0111527 |
| RYBP | RING1 and YY1 binding protein | 0.0111439 |
| MT1X | metallothionein 1X | 0.0108088 |
| WWOX | WW domain containing oxidoreductase | 0.0106855 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0102731 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0102443 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.0102394 |
| CD44 | CD44 molecule (Indian blood group) | 0.0101698 |
| NAV2 | neuron navigator 2 | 0.0100426 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.00995865 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.00981119 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.00976086 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.00973592 |
| EZR | ezrin | 0.00971021 |
| ICAM1 | intercellular adhesion molecule 1 | 0.00968922 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.00958297 |
| TXNRD1 | thioredoxin reductase 1 | 0.00957238 |
| TGM2 | transglutaminase 2 | 0.00956027 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.00955373 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.00950984 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00940164 |
| LDHA | lactate dehydrogenase A | 0.00938074 |
| ZNF292 | zinc finger protein 292 | 0.00929729 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.00927215 |
| PRRC2A | proline-rich coiled-coil 2A | 0.00924047 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.00915851 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.00910062 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.00882154 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.00871994 |
| RFWD3 | ring finger and WD repeat domain 3 | 0.00871357 |
| TFRC | transferrin receptor | 0.00858939 |
| EGR1 | early growth response 1 | 0.00858215 |
| KIAA1217 | KIAA1217 | 0.00850854 |
| CDCP1 | CUB domain containing protein 1 | 0.00845769 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00828716 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.00814105 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.00811972 |
| AGRN | agrin | 0.008116 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.00809058 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.00798485 |
| CCNL1 | cyclin L1 | 0.00795586 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.00786185 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.00782288 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.00774293 |
| DIAPH1 | diaphanous-related formin 1 | 0.00771926 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.00769492 |
| ECT2 | epithelial cell transforming 2 | 0.00769477 |
| TPM3 | tropomyosin 3 | 0.00767695 |
| SF1 | splicing factor 1 | 0.00762336 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 0.0076093 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.00757821 |
| FHL2 | four and a half LIM domains 2 | 0.00754505 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) | 0.00752528 |
| CUL3 | cullin 3 | 0.00740437 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.00733736 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.00731429 |
| SNX9 | sorting nexin 9 | 0.00728889 |
| CLIC4 | chloride intracellular channel 4 | 0.0072826 |
| XPO1 | exportin 1 | 0.00724267 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.00720819 |
| BARD1 | BRCA1 associated RING domain 1 | 0.00718641 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.277209 |
| VIM | vimentin | -0.270356 |
| HMGA2 | high mobility group AT-hook 2 | -0.138747 |
| CDH13 | cadherin 13 | -0.131216 |
| TMSB10 | thymosin beta 10 | -0.123819 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.121147 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0916189 |
| RAI14 | retinoic acid induced 14 | -0.0897609 |
| ASPH | aspartate beta-hydroxylase | -0.0873133 |
| IGF2 | insulin-like growth factor 2 | -0.082264 |
| COL5A1 | collagen, type V, alpha 1 | -0.077629 |
| DST | dystonin | -0.0735359 |
| EXT1 | exostosin glycosyltransferase 1 | -0.071867 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0703512 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0650581 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0566378 |
| FMN1 | formin 1 | -0.0557145 |
| LAMB3 | laminin, beta 3 | -0.0554388 |
| CANX | calnexin | -0.0520818 |
| CLMP | CXADR-like membrane protein | -0.0457044 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0446247 |
| AHNAK | AHNAK nucleoprotein | -0.044167 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0436371 |
| ACTG1 | actin gamma 1 | -0.0435146 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0432911 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0428453 |
| GLIS3 | GLIS family zinc finger 3 | -0.0423334 |
| LOX | lysyl oxidase | -0.0421948 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0417863 |
| TENM2 | teneurin transmembrane protein 2 | -0.0413124 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0411783 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0410008 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0404864 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0401408 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0397432 |
| MYO10 | myosin X | -0.0369945 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0364185 |
| PTMA | prothymosin, alpha | -0.0362779 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0351871 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0348469 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0347894 |
| IL1B | interleukin 1, beta | -0.0347391 |
| ENO1 | enolase 1, (alpha) | -0.0346324 |
| CCND1 | cyclin D1 | -0.0345557 |
| PCBP3 | poly(rC) binding protein 3 | -0.0344415 |
| RRBP1 | ribosome binding protein 1 | -0.0337172 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.033333 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0324276 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0320299 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0318737 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0318159 |
| SBF2 | SET binding factor 2 | -0.0311999 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0310287 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0308948 |
| NF1 | neurofibromin 1 | -0.0299089 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0292511 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0290789 |
| INHBA | inhibin, beta A | -0.0289355 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0286287 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0283457 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0281217 |
| RPS6 | ribosomal protein S6 | -0.028076 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.028044 |
| PDE10A | phosphodiesterase 10A | -0.0279876 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0279578 |
| PRELID2 | PRELI domain containing 2 | -0.0278697 |
| CUX1 | cut-like homeobox 1 | -0.0275919 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0274758 |
| GOLGB1 | golgin B1 | -0.0273072 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.027295 |
| USP34 | ubiquitin specific peptidase 34 | -0.0269213 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0268954 |
| MYO9A | myosin IXA | -0.0266291 |
| DNAAF9 | dynein axonemal assembly factor 9 | -0.0266074 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0263991 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0262579 |
| GRB10 | growth factor receptor-bound protein 10 | -0.026222 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.026126 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0260518 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.026018 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0258757 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0258066 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0254211 |
| FRMD4A | FERM domain containing 4A | -0.0253237 |
| TMEM165 | transmembrane protein 165 | -0.0251793 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0251504 |
| ANKRD12 | ankyrin repeat domain 12 | -0.025129 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0251166 |
| ANXA2 | annexin A2 | -0.0247672 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0244081 |
| NAV1 | neuron navigator 1 | -0.0243793 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0243352 |
| EGFR | epidermal growth factor receptor | -0.0242737 |
| MAP4 | microtubule-associated protein 4 | -0.0241866 |
| CALU | calumenin | -0.0240392 |
| EHBP1 | EH domain binding protein 1 | -0.0239813 |
| SEPTIN2 | septin 2 | -0.0239763 |
| MMP12 | matrix metallopeptidase 12 | -0.0233038 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0232324 |
| COL1A1 | collagen, type I, alpha 1 | -0.0232138 |
