| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bisoprolol (hemifumarate) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bisoprolol (hemifumarate)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0657208 |
| MT1X | metallothionein 1X | 0.0488196 |
| SLC12A8 | solute carrier family 12, member 8 | 0.0473823 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0458454 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0440786 |
| ATP13A3 | ATPase type 13A3 | 0.0391654 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0336022 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0331659 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0321912 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0298937 |
| COL5A1 | collagen, type V, alpha 1 | 0.0287533 |
| FLNA | filamin A, alpha | 0.0234616 |
| TGFB2 | transforming growth factor, beta 2 | 0.0230613 |
| NUP153 | nucleoporin 153kDa | 0.0226613 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0221583 |
| NUP58 | nucleoporin 58 | 0.0201144 |
| FLNB | filamin B, beta | 0.0196754 |
| ARF4 | ADP-ribosylation factor 4 | 0.0195156 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0194769 |
| GPR107 | G protein-coupled receptor 107 | 0.0189435 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0188661 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0177524 |
| SMAD3 | SMAD family member 3 | 0.017307 |
| NEK7 | NIMA-related kinase 7 | 0.0170349 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0161383 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0157922 |
| TXNRD1 | thioredoxin reductase 1 | 0.015454 |
| USP3 | ubiquitin specific peptidase 3 | 0.0154405 |
| NCKAP1 | NCK-associated protein 1 | 0.0151082 |
| ARF1 | ADP-ribosylation factor 1 | 0.0149665 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0148334 |
| TMEM41B | transmembrane protein 41B | 0.0146721 |
| HLA-C | major histocompatibility complex, class I, C | 0.0146553 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0146157 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0145565 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0140182 |
| TMEM39A | transmembrane protein 39A | 0.0137707 |
| GANAB | glucosidase, alpha; neutral AB | 0.0137555 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0131066 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0130115 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0128925 |
| GOLGA2 | golgin A2 | 0.0128532 |
| TFG | TRK-fused gene | 0.012767 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0126717 |
| RBM39 | RNA binding motif protein 39 | 0.0125125 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0123144 |
| SCFD2 | sec1 family domain containing 2 | 0.0118954 |
| SNX4 | sorting nexin 4 | 0.0117051 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0116715 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0116102 |
| SRP54 | signal recognition particle 54kDa | 0.0115872 |
| BCL2L1 | BCL2-like 1 | 0.0115812 |
| SUCO | SUN domain containing ossification factor | 0.0115429 |
| CCNL1 | cyclin L1 | 0.0115042 |
| WDR43 | WD repeat domain 43 | 0.0113266 |
| ZNF841 | zinc finger protein 841 | 0.0112869 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0112005 |
| DDB1 | damage-specific DNA binding protein 1, 127kDa | 0.0111119 |
| RAB18 | RAB18, member RAS oncogene family | 0.0109791 |
| TPD52 | tumor protein D52 | 0.0105565 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | 0.0103818 |
| PRKAA1 | protein kinase, AMP-activated, alpha 1 catalytic subunit | 0.010265 |
| CPSF6 | cleavage and polyadenylation specific factor 6, 68kDa | 0.0102369 |
| WRN | Werner syndrome, RecQ helicase-like | 0.0101908 |
| SF1 | splicing factor 1 | 0.0101064 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0100639 |
| LAMA5 | laminin, alpha 5 | 0.0100194 |
| HEG1 | heart development protein with EGF-like domains 1 | 0.00994879 |
| ODF2 | outer dense fiber of sperm tails 2 | 0.00992278 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.00976772 |
| MED14 | mediator complex subunit 14 | 0.00974913 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.009745 |
| QRICH1 | glutamine-rich 1 | 0.00972454 |
| GCN1 | GCN1 activator of EIF2AK4 | 0.00969317 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.00947062 |
| ATXN2L | ataxin 2-like | 0.00947009 |
| H1-0 | H1.0 linker histone | 0.00940378 |
| UBQLN1 | ubiquilin 1 | 0.00936163 |
| AMBRA1 | autophagy/beclin-1 regulator 1 | 0.00934655 |
| BARD1 | BRCA1 associated RING domain 1 | 0.00925962 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.00923859 |
| DENND4C | DENN/MADD domain containing 4C | 0.00922951 |
| PPME1 | protein phosphatase methylesterase 1 | 0.00916297 |
| LONP2 | lon peptidase 2, peroxisomal | 0.00913357 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.00912696 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.00904618 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.00900119 |
| EVI5 | ecotropic viral integration site 5 | 0.00899381 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.00897022 |
| SLC6A4 | solute carrier family 6 (neurotransmitter transporter), member 4 | 0.00895038 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00891727 |
| LOC112694756 | uncharaterized LOC112694756 | 0.00885891 |
| NDFIP2 | Nedd4 family interacting protein 2 | 0.00885291 |
| UCK2 | uridine-cytidine kinase 2 | 0.00878282 |
| SAFB2 | scaffold attachment factor B2 | 0.00876766 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.00874536 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.00869302 |
| RUSC2 | RUN and SH3 domain containing 2 | 0.00866493 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.00863949 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.00861863 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.242568 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.209654 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.194323 |
| HLA-B | major histocompatibility complex, class I, B | -0.134068 |
| MT2A | metallothionein 2A | -0.121929 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.116965 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.115191 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.115181 |
| FTL | ferritin, light polypeptide | -0.115115 |
| NDRG1 | N-myc downstream regulated 1 | -0.109239 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.100809 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0935353 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0933633 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0917188 |
| VIM | vimentin | -0.0905554 |
| ASPH | aspartate beta-hydroxylase | -0.0846103 |
| RPS6 | ribosomal protein S6 | -0.0799623 |
| POTEF | POTE ankyrin domain family, member F | -0.0760543 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0751999 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0717043 |
| ENO1 | enolase 1, (alpha) | -0.0692982 |
| ACTG1 | actin gamma 1 | -0.068668 |
| ANXA2 | annexin A2 | -0.0669673 |
| B2M | beta-2-microglobulin | -0.0658447 |
| TMSB10 | thymosin beta 10 | -0.0656775 |
| DEK | DEK proto-oncogene | -0.0565984 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0540555 |
| LDHA | lactate dehydrogenase A | -0.0539191 |
| RAI14 | retinoic acid induced 14 | -0.0531168 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0511954 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0502187 |
| RPL35A | ribosomal protein L35a | -0.049725 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0491516 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0472966 |
| INTS6 | integrator complex subunit 6 | -0.0472025 |
| DST | dystonin | -0.0470206 |
| MAP1B | microtubule-associated protein 1B | -0.046681 |
| DTNA | dystrobrevin, alpha | -0.04604 |
| PTMA | prothymosin, alpha | -0.0458523 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.044842 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.044168 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0426105 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0423883 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0418884 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0410252 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0407579 |
| ERBIN | erbb2 interacting protein | -0.0401204 |
| RPS8 | ribosomal protein S8 | -0.0400772 |
| ZNF432 | zinc finger protein 432 | -0.0393658 |
| NAV2 | neuron navigator 2 | -0.0388309 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0387853 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0378581 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0378377 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0377488 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0373503 |
| RPL23 | ribosomal protein L23 | -0.0370179 |
| TMSB4X | thymosin beta 4, X-linked | -0.03621 |
| DIAPH3 | diaphanous-related formin 3 | -0.0359874 |
| TPM4 | tropomyosin 4 | -0.0359333 |
| RPLP2 | ribosomal protein, large, P2 | -0.0358413 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0352046 |
| CD44 | CD44 molecule (Indian blood group) | -0.0346491 |
| EGFR | epidermal growth factor receptor | -0.0345362 |
| SMYD3 | SET and MYND domain containing 3 | -0.0344703 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0341708 |
| PFN1 | profilin 1 | -0.0341231 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0339599 |
| CENPF | centromere protein F, 350/400kDa | -0.0337169 |
| PLCB4 | phospholipase C, beta 4 | -0.0332946 |
| CANX | calnexin | -0.0324733 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0321821 |
| ATXN1 | ataxin 1 | -0.0320974 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0319846 |
| ZNF804A | zinc finger protein 804A | -0.0319224 |
| RPL11 | ribosomal protein L11 | -0.0315605 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0313903 |
| KRT7 | keratin 7, type II | -0.0313654 |
| CCND1 | cyclin D1 | -0.0311631 |
| TLE4 | transducin-like enhancer of split 4 | -0.0306024 |
| MMP12 | matrix metallopeptidase 12 | -0.0304618 |
| PRELID2 | PRELI domain containing 2 | -0.0301022 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0299212 |
| PTK2 | protein tyrosine kinase 2 | -0.0298008 |
| GLIS3 | GLIS family zinc finger 3 | -0.0295061 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.029427 |
| S100A6 | S100 calcium binding protein A6 | -0.0291852 |
| RPL12 | ribosomal protein L12 | -0.0288817 |
| RPS3 | ribosomal protein S3 | -0.0288685 |
| GOLGB1 | golgin B1 | -0.0288341 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0288107 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0285413 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0283733 |
| RAD51B | RAD51 paralog B | -0.0283381 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0283117 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0282441 |
| RND3 | Rho family GTPase 3 | -0.028185 |
| RPL5 | ribosomal protein L5 | -0.0281116 |
| RPLP1 | ribosomal protein, large, P1 | -0.0276963 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0276618 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0275447 |
