| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bisoprolol (hemifumarate) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bisoprolol (hemifumarate)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.106142 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0616417 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0559989 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0553372 |
| VCL | vinculin | 0.0552789 |
| PGK1 | phosphoglycerate kinase 1 | 0.0508086 |
| CTSB | cathepsin B | 0.0465731 |
| PKM | pyruvate kinase, muscle | 0.0459519 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0446553 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0432893 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0426034 |
| SMAD3 | SMAD family member 3 | 0.0411178 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0397143 |
| CD44 | CD44 molecule (Indian blood group) | 0.037506 |
| RTN4 | reticulon 4 | 0.037425 |
| NUP58 | nucleoporin 58 | 0.0351476 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0344727 |
| RPS23 | ribosomal protein S23 | 0.0324663 |
| RPS25 | ribosomal protein S25 | 0.032057 |
| VGF | VGF nerve growth factor inducible | 0.0320201 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0319305 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0316495 |
| FN1 | fibronectin 1 | 0.0295701 |
| RPL4 | ribosomal protein L4 | 0.028771 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0286861 |
| POTEF | POTE ankyrin domain family, member F | 0.0281019 |
| LDHA | lactate dehydrogenase A | 0.0274156 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0271392 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0264181 |
| TPM4 | tropomyosin 4 | 0.0260952 |
| CALR | calreticulin | 0.025874 |
| TMEM123 | transmembrane protein 123 | 0.0257739 |
| AHNAK | AHNAK nucleoprotein | 0.0257215 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0254259 |
| IL6ST | interleukin 6 signal transducer | 0.0241258 |
| RPL7A | ribosomal protein L7a | 0.0240367 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0239025 |
| UBC | ubiquitin C | 0.0236934 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0234164 |
| CDK17 | cyclin-dependent kinase 17 | 0.0230682 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0229715 |
| ANXA2 | annexin A2 | 0.0228151 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0225957 |
| RPLP0 | ribosomal protein, large, P0 | 0.0224153 |
| RLF | rearranged L-myc fusion | 0.0222797 |
| ZNF292 | zinc finger protein 292 | 0.0220746 |
| ACTN1 | actinin, alpha 1 | 0.0220125 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0216924 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0214922 |
| FRMD6 | FERM domain containing 6 | 0.0213754 |
| RPS24 | ribosomal protein S24 | 0.0212594 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0212498 |
| CCN2 | cellular communication network factor 2 | 0.0209159 |
| RPL36A | ribosomal protein L36a | 0.0206388 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0202613 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0202587 |
| YTHDF3 | YTH N(6)-methyladenosine RNA binding protein 3 | 0.0200887 |
| FLNA | filamin A, alpha | 0.0197315 |
| TFG | TRK-fused gene | 0.0196972 |
| BDNF | brain-derived neurotrophic factor | 0.0196501 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0196278 |
| NUP153 | nucleoporin 153kDa | 0.0194268 |
| AXL | AXL receptor tyrosine kinase | 0.019416 |
| RPL35A | ribosomal protein L35a | 0.0191463 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0190852 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0183022 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.018112 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0180561 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0179895 |
| VDAC1 | voltage-dependent anion channel 1 | 0.0179338 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0177986 |
| RBM27 | RNA binding motif protein 27 | 0.0176916 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0176627 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0175569 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0174368 |
| QKI | QKI, KH domain containing, RNA binding | 0.0173011 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0172535 |
| MTF2 | metal response element binding transcription factor 2 | 0.0170032 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0168834 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0165153 |
| RPS15 | ribosomal protein S15 | 0.0164594 |
| WDR43 | WD repeat domain 43 | 0.0163974 |
| NRP2 | neuropilin 2 | 0.0162823 |
| HLA-E | major histocompatibility complex, class I, E | 0.0160328 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0160081 |
| EIF3M | eukaryotic translation initiation factor 3, subunit M | 0.0159814 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0158657 |
| PYROXD1 | pyridine nucleotide-disulphide oxidoreductase domain 1 | 0.0158288 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0158061 |
| MORF4L1 | mortality factor 4 like 1 | 0.0157189 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | 0.0156677 |
| RASA2 | RAS p21 protein activator 2 | 0.0156587 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.015598 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.015596 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0155128 |
| TAPBP | TAP binding protein (tapasin) | 0.0154622 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0153293 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.0152578 |
| FOXJ3 | forkhead box J3 | 0.015117 |
| TUBA1B | tubulin, alpha 1b | 0.0150314 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EFNA5 | ephrin-A5 | -0.256704 |
| DTNA | dystrobrevin, alpha | -0.186415 |
| EXT1 | exostosin glycosyltransferase 1 | -0.170491 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.154548 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.13626 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.112859 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.108498 |
| ASPH | aspartate beta-hydroxylase | -0.102224 |
| TMSB10 | thymosin beta 10 | -0.101887 |
| LSAMP | limbic system-associated membrane protein | -0.101863 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0970271 |
| GPC6 | glypican 6 | -0.0870125 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0867671 |
| FTL | ferritin, light polypeptide | -0.0850184 |
| MT2A | metallothionein 2A | -0.0848272 |
| RUNX1 | runt-related transcription factor 1 | -0.0838878 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0833759 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0815271 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0768587 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0764039 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0758653 |
| PTK2 | protein tyrosine kinase 2 | -0.0753762 |
| NTM | neurotrimin | -0.0749657 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0707113 |
| CDH13 | cadherin 13 | -0.0700665 |
| YBX3 | Y box binding protein 3 | -0.0698178 |
| KIAA1549L | KIAA1549-like | -0.069137 |
| PRKCE | protein kinase C, epsilon | -0.0681631 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0665461 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0654241 |
| RPS6 | ribosomal protein S6 | -0.0654107 |
| RPS19 | ribosomal protein S19 | -0.064813 |
| RPL23 | ribosomal protein L23 | -0.0639603 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0633003 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0620024 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0617791 |
| HDAC9 | histone deacetylase 9 | -0.0575652 |
| RPS3 | ribosomal protein S3 | -0.0566643 |
| DST | dystonin | -0.0550715 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0535938 |
| FMNL2 | formin-like 2 | -0.0518569 |
| RPL37A | ribosomal protein L37a | -0.0509242 |
| TLE4 | transducin-like enhancer of split 4 | -0.049919 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.049662 |
| ZNF804A | zinc finger protein 804A | -0.0495599 |
| RPL36 | ribosomal protein L36 | -0.0489471 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0470539 |
| NAV1 | neuron navigator 1 | -0.0448967 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0446412 |
| RPL26 | ribosomal protein L26 | -0.0429683 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0424736 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0414931 |
| MSR1 | macrophage scavenger receptor 1 | -0.041258 |
| USP34 | ubiquitin specific peptidase 34 | -0.0410604 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.038825 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0385033 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0384054 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0378431 |
| RIGI | RNA sensor RIG-I | -0.0376336 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0371165 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.036984 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0366985 |
| NABP1 | nucleic acid binding protein 1 | -0.0361295 |
| HMGA2 | high mobility group AT-hook 2 | -0.0360932 |
| RPLP1 | ribosomal protein, large, P1 | -0.0359263 |
| EGR1 | early growth response 1 | -0.0358834 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0358492 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0357697 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0355988 |
| TMPRSS15 | transmembrane protease, serine 15 | -0.0354311 |
| RPL13A | ribosomal protein L13a | -0.0353929 |
| NDRG1 | N-myc downstream regulated 1 | -0.0353168 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0351503 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0351264 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0351171 |
| ZNF638 | zinc finger protein 638 | -0.0344134 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0341399 |
| DSCAM | Down syndrome cell adhesion molecule | -0.033957 |
| SSH2 | slingshot protein phosphatase 2 | -0.0337828 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0337109 |
| NF1 | neurofibromin 1 | -0.033617 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0334866 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0329814 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0329273 |
| DGKI | diacylglycerol kinase, iota | -0.0328377 |
| AEBP2 | AE binding protein 2 | -0.0328374 |
| KIAA1217 | KIAA1217 | -0.0324777 |
| PTCHD4 | patched domain containing 4 | -0.0322445 |
| PRELID2 | PRELI domain containing 2 | -0.0321687 |
| GOLGA4 | golgin A4 | -0.0319192 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0318728 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0315989 |
| RPL12 | ribosomal protein L12 | -0.0311794 |
| MYO10 | myosin X | -0.0309602 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0308934 |
| ACTG1 | actin gamma 1 | -0.0302144 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0299331 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0299052 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | -0.0297991 |
| RPS2 | ribosomal protein S2 | -0.0297036 |
