| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bisoprolol (hemifumarate) perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bisoprolol (hemifumarate)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | 0.115093 |
| VCL | vinculin | 0.0869198 |
| NPSR1 | neuropeptide S receptor 1 | 0.0784397 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0519584 |
| TNS4 | tensin 4 | 0.0514874 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0511944 |
| ACTG1 | actin gamma 1 | 0.0468534 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0435841 |
| TPM4 | tropomyosin 4 | 0.0410476 |
| RPL35A | ribosomal protein L35a | 0.0383552 |
| FHIT | fragile histidine triad | 0.0375455 |
| SMYD3 | SET and MYND domain containing 3 | 0.035892 |
| ONECUT3 | one cut homeobox 3 | 0.0352876 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0348747 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0347429 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0341119 |
| EGFR | epidermal growth factor receptor | 0.0337533 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0335347 |
| RAD51B | RAD51 paralog B | 0.032018 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0317534 |
| FLNB | filamin B, beta | 0.0317198 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0315644 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0273258 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0263744 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.0259725 |
| TFF1 | trefoil factor 1 | 0.0256767 |
| TMEM45B | transmembrane protein 45B | 0.025309 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0248973 |
| RPL31 | ribosomal protein L31 | 0.0246127 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0245295 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0244049 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0242443 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0237884 |
| RPS29 | ribosomal protein S29 | 0.0236842 |
| RPS24 | ribosomal protein S24 | 0.0234964 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.0234233 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | 0.0231991 |
| CUX1 | cut-like homeobox 1 | 0.0231281 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0230519 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0227439 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0224623 |
| HM13 | histocompatibility (minor) 13 | 0.0222908 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0222237 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.022145 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0219618 |
| FRMD5 | FERM domain containing 5 | 0.0219504 |
| RPS25 | ribosomal protein S25 | 0.021766 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0216803 |
| EXOC4 | exocyst complex component 4 | 0.0216324 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.021407 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0212937 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0211769 |
| SEPTIN9 | septin 9 | 0.0210445 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.020863 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | 0.020802 |
| IER3 | immediate early response 3 | 0.0206823 |
| RPL9 | ribosomal protein L9 | 0.0204449 |
| RPS13 | ribosomal protein S13 | 0.0203991 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0202284 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0201867 |
| MYO1E | myosin IE | 0.0199089 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.019533 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0193538 |
| DENND1A | DENN/MADD domain containing 1A | 0.0193033 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | 0.0191877 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0188496 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0185067 |
| PRSS3 | protease, serine, 3 | 0.0184089 |
| PRELID2 | PRELI domain containing 2 | 0.0183834 |
| INTS6 | integrator complex subunit 6 | 0.0182678 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0180677 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0176477 |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | 0.0174291 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0173033 |
| FLNA | filamin A, alpha | 0.0172053 |
| RPLP2 | ribosomal protein, large, P2 | 0.0171558 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0171236 |
| RPS23 | ribosomal protein S23 | 0.0170501 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0170018 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0166533 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0166288 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0165829 |
| TUFT1 | tuftelin 1 | 0.0164784 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0164705 |
| TPM1 | tropomyosin 1 (alpha) | 0.0162391 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0161276 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0161249 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0160809 |
| DIAPH2 | diaphanous-related formin 2 | 0.0159868 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | 0.015971 |
| CCDC91 | coiled-coil domain containing 91 | 0.0159379 |
| LAMB3 | laminin, beta 3 | 0.0158508 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0158212 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | 0.0156895 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0156014 |
| HDAC4 | histone deacetylase 4 | 0.0155713 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0155565 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0155328 |
| DYM | dymeclin | 0.0154894 |
| PDE10A | phosphodiesterase 10A | 0.0153899 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.337518 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.193925 |
| PTMA | prothymosin, alpha | -0.164362 |
| TXNIP | thioredoxin interacting protein | -0.129142 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.122351 |
| EZR | ezrin | -0.117179 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.112433 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.106247 |
| LMO7 | LIM domain 7 | -0.106043 |
| ITGA6 | integrin, alpha 6 | -0.0982104 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0931761 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0733584 |
| DSPP | dentin sialophosphoprotein | -0.0713475 |
| RNF145 | ring finger protein 145 | -0.070569 |
| TMSB10 | thymosin beta 10 | -0.0687914 |
| LDHA | lactate dehydrogenase A | -0.0660078 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0647324 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0647275 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0639153 |
| EPCAM | epithelial cell adhesion molecule | -0.0636049 |
| ANXA2 | annexin A2 | -0.0621706 |
| MED13L | mediator complex subunit 13-like | -0.0600075 |
| YBX1 | Y box binding protein 1 | -0.0591451 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.0588698 |
| ANXA1 | annexin A1 | -0.0580373 |
| PGK1 | phosphoglycerate kinase 1 | -0.0580177 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0575939 |
| WDR45B | WD repeat domain 45B | -0.0575367 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0571014 |
| FNBP1L | formin binding protein 1-like | -0.0557369 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0556064 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0530115 |
| RPL12 | ribosomal protein L12 | -0.0520789 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0516934 |
| RPLP1 | ribosomal protein, large, P1 | -0.051074 |
| RPLP0 | ribosomal protein, large, P0 | -0.0487241 |
| EMP1 | epithelial membrane protein 1 | -0.0477913 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0471189 |
| RPL18 | ribosomal protein L18 | -0.0465308 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0465256 |
| RPS6 | ribosomal protein S6 | -0.0462508 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0449644 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0440964 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0434536 |
| FAM13A | family with sequence similarity 13, member A | -0.0429049 |
| KIF5B | kinesin family member 5B | -0.0420369 |
| RBM39 | RNA binding motif protein 39 | -0.0417492 |
| S100A6 | S100 calcium binding protein A6 | -0.0417098 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0414213 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0405583 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0404261 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0400303 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0395139 |
| GOLGA4 | golgin A4 | -0.0394579 |
| ZNF292 | zinc finger protein 292 | -0.0392736 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0389604 |
| PCBP2 | poly(rC) binding protein 2 | -0.0388398 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0387813 |
| RPS19 | ribosomal protein S19 | -0.0383364 |
| ENO1 | enolase 1, (alpha) | -0.0383174 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0378105 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0377855 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0376733 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0374305 |
| RPL32 | ribosomal protein L32 | -0.0372533 |
| AFF1 | AF4/FMR2 family, member 1 | -0.03632 |
| USP6NL | USP6 N-terminal like | -0.036044 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0359364 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0357883 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0344072 |
| TPD52 | tumor protein D52 | -0.0343505 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0341983 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | -0.0341549 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0340685 |
| CLCN3 | chloride channel, voltage-sensitive 3 | -0.0339724 |
| YBX3 | Y box binding protein 3 | -0.0339455 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0337735 |
| TFG | TRK-fused gene | -0.0334989 |
| COPA | coatomer protein complex, subunit alpha | -0.0334908 |
| RPL36 | ribosomal protein L36 | -0.0331172 |
| CANX | calnexin | -0.0329584 |
| RPL34 | ribosomal protein L34 | -0.0324064 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0323397 |
| SHROOM3 | shroom family member 3 | -0.0321002 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0319724 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0319335 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0315654 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0313949 |
| ATF4 | activating transcription factor 4 | -0.0313536 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0312869 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0312549 |
| HELZ | helicase with zinc finger | -0.0310379 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0305868 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.030366 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | -0.030281 |
| NUP58 | nucleoporin 58 | -0.0302069 |
| PCM1 | pericentriolar material 1 | -0.0300864 |
| HMGA1 | high mobility group AT-hook 1 | -0.0300675 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.029792 |
| JMJD1C | jumonji domain containing 1C | -0.0296927 |
