| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bisoprolol (hemifumarate) perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bisoprolol (hemifumarate)_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | 0.24267 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.147886 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.120143 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.108003 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0983932 |
| RPLP2 | ribosomal protein, large, P2 | 0.0821917 |
| RPL35A | ribosomal protein L35a | 0.0768253 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0731933 |
| RPS23 | ribosomal protein S23 | 0.0701964 |
| GOLGA4 | golgin A4 | 0.0701471 |
| RPS13 | ribosomal protein S13 | 0.0670078 |
| RPS25 | ribosomal protein S25 | 0.0636707 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0628581 |
| HLA-B | major histocompatibility complex, class I, B | 0.0587583 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0570896 |
| FAT1 | FAT atypical cadherin 1 | 0.0534213 |
| RPL7A | ribosomal protein L7a | 0.0515136 |
| CANX | calnexin | 0.050948 |
| RPL36A | ribosomal protein L36a | 0.0466065 |
| RPL38 | ribosomal protein L38 | 0.0464278 |
| RPL4 | ribosomal protein L4 | 0.0452583 |
| FOXO1 | forkhead box O1 | 0.0427535 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0416977 |
| RPS29 | ribosomal protein S29 | 0.0387184 |
| UGT1A6 | UDP glucuronosyltransferase 1 family, polypeptide A6 | 0.0385574 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0380493 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.037756 |
| RPS24 | ribosomal protein S24 | 0.0367947 |
| RPS11 | ribosomal protein S11 | 0.0340824 |
| RPS15 | ribosomal protein S15 | 0.0335227 |
| PKP2 | plakophilin 2 | 0.0318916 |
| UBC | ubiquitin C | 0.0317079 |
| CLTC | clathrin, heavy chain (Hc) | 0.0315655 |
| ABHD17C | abhydrolase domain containing 17C | 0.0315512 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.030855 |
| CCPG1 | cell cycle progression 1 | 0.0306053 |
| AGR2 | anterior gradient 2 | 0.0298541 |
| RPL8 | ribosomal protein L8 | 0.0294946 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0292425 |
| TXNRD1 | thioredoxin reductase 1 | 0.0291464 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0290198 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0286472 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0284464 |
| PTEN | phosphatase and tensin homolog | 0.0281765 |
| IER3 | immediate early response 3 | 0.0271938 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.027176 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0270151 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0270079 |
| RPS27A | ribosomal protein S27a | 0.0267485 |
| HM13 | histocompatibility (minor) 13 | 0.0262948 |
| RPL28 | ribosomal protein L28 | 0.026046 |
| JMY | junction mediating and regulatory protein, p53 cofactor | 0.0259194 |
| EREG | epiregulin | 0.0258778 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0258225 |
| ATXN1 | ataxin 1 | 0.0257497 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0254629 |
| SHROOM3 | shroom family member 3 | 0.0253239 |
| CALR | calreticulin | 0.0253211 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0252967 |
| SEC24D | SEC24 family member D | 0.0252449 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0251023 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | 0.0250237 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0247649 |
| CEP95 | centrosomal protein 95kDa | 0.0247242 |
| HDLBP | high density lipoprotein binding protein | 0.0247178 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.024605 |
| GOLGB1 | golgin B1 | 0.0244756 |
| RPL31 | ribosomal protein L31 | 0.0244305 |
| GLG1 | golgi glycoprotein 1 | 0.0242594 |
| WWC1 | WW and C2 domain containing 1 | 0.0240565 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0235902 |
| VDAC1 | voltage-dependent anion channel 1 | 0.0225478 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0225097 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0223181 |
| RRBP1 | ribosome binding protein 1 | 0.0221488 |
| NDRG1 | N-myc downstream regulated 1 | 0.0214915 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0213866 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0213213 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0212467 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0209552 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.020699 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0205449 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0205327 |
| HLA-E | major histocompatibility complex, class I, E | 0.0205309 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0204917 |
| RPS10 | ribosomal protein S10 | 0.0203832 |
| GOLGA2 | golgin A2 | 0.0202694 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0202237 |
| RNF145 | ring finger protein 145 | 0.0201037 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0200859 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0200346 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.0197328 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0197305 |
| XPC | xeroderma pigmentosum, complementation group C | 0.0196662 |
| TMEM263 | transmembrane protein 263 | 0.0193045 |
| RAB5A | RAB5A, member RAS oncogene family | 0.0190903 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.0188127 |
| TSPAN8 | tetraspanin 8 | 0.0186282 |
| NKTR | natural killer cell triggering receptor | 0.0184128 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0183844 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.131507 |
| TMSB10 | thymosin beta 10 | -0.0956372 |
| ANXA2 | annexin A2 | -0.0909779 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0844445 |
| RPS19 | ribosomal protein S19 | -0.0826935 |
| RPL23 | ribosomal protein L23 | -0.0823129 |
| RPLP1 | ribosomal protein, large, P1 | -0.0820617 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0766966 |
| RPS3 | ribosomal protein S3 | -0.0735657 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0716467 |
| LMO7 | LIM domain 7 | -0.0687595 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0657092 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0649199 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0576714 |
| RPS6 | ribosomal protein S6 | -0.0575833 |
| MSI2 | musashi RNA-binding protein 2 | -0.0567484 |
| FRMD5 | FERM domain containing 5 | -0.0566047 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0560976 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0553179 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0548983 |
| SPINK13 | serine peptidase inhibitor, Kazal type 13 (putative) | -0.0538297 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0537305 |
| RPL18 | ribosomal protein L18 | -0.0537062 |
| EZR | ezrin | -0.0532353 |
| RPL5 | ribosomal protein L5 | -0.051405 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0480194 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0476665 |
| CLDN4 | claudin 4 | -0.0471139 |
| RPS17 | ribosomal protein S17 | -0.0468722 |
| CALB1 | calbindin 1, 28kDa | -0.0463016 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0461501 |
| RPL13A | ribosomal protein L13a | -0.0460493 |
| RPL34 | ribosomal protein L34 | -0.0454462 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0447938 |
| RPL36 | ribosomal protein L36 | -0.0446771 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0444387 |
| INTS6 | integrator complex subunit 6 | -0.0442665 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0437012 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0425247 |
| MYO5B | myosin VB | -0.0420726 |
| PDLIM5 | PDZ and LIM domain 5 | -0.041937 |
| MX1 | MX dynamin-like GTPase 1 | -0.0408493 |
| OXSR1 | oxidative stress responsive 1 | -0.0404922 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0392814 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0392096 |
| RBM25 | RNA binding motif protein 25 | -0.0388736 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.038718 |
| RPL26 | ribosomal protein L26 | -0.0382145 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0376924 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0374239 |
| SP100 | SP100 nuclear antigen | -0.0373573 |
| RCOR1 | REST corepressor 1 | -0.0366704 |
| RPS8 | ribosomal protein S8 | -0.0364695 |
| RPL9 | ribosomal protein L9 | -0.03636 |
| PLSCR1 | phospholipid scramblase 1 | -0.0358012 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0355754 |
| DENND1A | DENN/MADD domain containing 1A | -0.0354336 |
| PARD3 | par-3 family cell polarity regulator | -0.0351244 |
| DSG3 | desmoglein 3 | -0.0347958 |
| RNF213 | ring finger protein 213 | -0.0346229 |
| YBX3 | Y box binding protein 3 | -0.0346203 |
| UBAP2 | ubiquitin associated protein 2 | -0.0346148 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0344725 |
| MT2A | metallothionein 2A | -0.0344423 |
| SLTM | SAFB-like, transcription modulator | -0.0341885 |
| RIMKLB | ribosomal modification protein rimK-like family member B | -0.0339087 |
| MYO1E | myosin IE | -0.0338967 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0333209 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0332394 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0330701 |
| DSPP | dentin sialophosphoprotein | -0.0325427 |
| RIGI | RNA sensor RIG-I | -0.0325415 |
| RPL19 | ribosomal protein L19 | -0.0318878 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | -0.0311607 |
| COBL | cordon-bleu WH2 repeat protein | -0.0302263 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.030158 |
| CUX1 | cut-like homeobox 1 | -0.0297895 |
| PARD3B | par-3 family cell polarity regulator beta | -0.029727 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0296152 |
| RPS27 | ribosomal protein S27 | -0.0294437 |
| RPL12 | ribosomal protein L12 | -0.0291834 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0289706 |
| PCBP2 | poly(rC) binding protein 2 | -0.0288978 |
| SVIL | supervillin | -0.028661 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0286155 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0283445 |
| CTBP2 | C-terminal binding protein 2 | -0.0280421 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.0279313 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0278728 |
| TC2N | tandem C2 domains, nuclear | -0.0276889 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0276481 |
| TJP1 | tight junction protein 1 | -0.0275738 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.0273325 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0272183 |
| TPI1 | triosephosphate isomerase 1 | -0.0269287 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.026915 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | -0.0268303 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0267951 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0265951 |
| PATJ | PATJ crumbs cell polarity complex component | -0.026556 |
