| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bisoprolol (hemifumarate) perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bisoprolol (hemifumarate)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.0913374 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0730641 |
| VIM | vimentin | 0.068363 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0586342 |
| RPL35A | ribosomal protein L35a | 0.05298 |
| IER3 | immediate early response 3 | 0.0509389 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0445969 |
| TMSB10 | thymosin beta 10 | 0.038505 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0382284 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0379952 |
| RPLP2 | ribosomal protein, large, P2 | 0.0349579 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0349359 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0340482 |
| RPS24 | ribosomal protein S24 | 0.032966 |
| RPS25 | ribosomal protein S25 | 0.0315813 |
| PARD3 | par-3 family cell polarity regulator | 0.0299151 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0298182 |
| GLCCI1 | glucocorticoid induced 1 | 0.0283662 |
| C15ORF48 | chromosome 15 open reading frame 48 | 0.0271629 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0268085 |
| EGR1 | early growth response 1 | 0.026308 |
| VCL | vinculin | 0.025692 |
| ZNF804A | zinc finger protein 804A | 0.0253851 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0253593 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0250314 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0245184 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0238456 |
| MAP1B | microtubule-associated protein 1B | 0.0238053 |
| COL12A1 | collagen, type XII, alpha 1 | 0.0236657 |
| S100A10 | S100 calcium binding protein A10 | 0.0235953 |
| MECOM | MDS1 and EVI1 complex locus | 0.02297 |
| CLMP | CXADR-like membrane protein | 0.0229418 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0228281 |
| CDK14 | cyclin-dependent kinase 14 | 0.022704 |
| MEMO1 | mediator of cell motility 1 | 0.0220322 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0219542 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0217336 |
| CUX1 | cut-like homeobox 1 | 0.0215661 |
| USP3 | ubiquitin specific peptidase 3 | 0.0214608 |
| VDAC1 | voltage-dependent anion channel 1 | 0.0208272 |
| NAV1 | neuron navigator 1 | 0.0207989 |
| CAVIN1 | caveolae associated protein 1 | 0.020606 |
| ABI1 | abl-interactor 1 | 0.0201914 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0197312 |
| CALR | calreticulin | 0.0195933 |
| HMGA2 | high mobility group AT-hook 2 | 0.0195744 |
| RPLP0 | ribosomal protein, large, P0 | 0.0194705 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0188911 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0188516 |
| RPLP1 | ribosomal protein, large, P1 | 0.0186571 |
| HEG1 | heart development protein with EGF-like domains 1 | 0.0183568 |
| CDH13 | cadherin 13 | 0.018235 |
| RPS23 | ribosomal protein S23 | 0.0181814 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0180301 |
| CCNI | cyclin I | 0.0179831 |
| RPS11 | ribosomal protein S11 | 0.0176736 |
| HAS2 | hyaluronan synthase 2 | 0.0174287 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0174106 |
| MARS1 | methionyl-tRNA synthetase 1 | 0.017331 |
| EZR | ezrin | 0.0173275 |
| POU2F1 | POU class 2 homeobox 1 | 0.0170755 |
| ACTG1 | actin gamma 1 | 0.0170593 |
| ACTN4 | actinin, alpha 4 | 0.0170342 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0169409 |
| RPL7A | ribosomal protein L7a | 0.0167954 |
| RPL8 | ribosomal protein L8 | 0.0165033 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0164574 |
| TBL1X | transducin (beta)-like 1X-linked | 0.0157908 |
| NRG1 | neuregulin 1 | 0.0157779 |
| OXR1 | oxidation resistance 1 | 0.0156511 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0156276 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0153152 |
| NCOA2 | nuclear receptor coactivator 2 | 0.0153053 |
| MEF2A | myocyte enhancer factor 2A | 0.0151774 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.0151418 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.015118 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0150671 |
| PRSS23 | protease, serine, 23 | 0.0150598 |
| RPL32 | ribosomal protein L32 | 0.0150224 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0148893 |
| RPS16 | ribosomal protein S16 | 0.0147525 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0146749 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0144232 |
| ENOSF1 | enolase superfamily member 1 | 0.0144222 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0143881 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0142835 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0140447 |
| TMEM263 | transmembrane protein 263 | 0.0140314 |
| MAP4 | microtubule-associated protein 4 | 0.0138775 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0136658 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0135862 |
| CDK12 | cyclin-dependent kinase 12 | 0.0134363 |
| ADAM12 | ADAM metallopeptidase domain 12 | 0.0133763 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0133615 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0130596 |
| HLA-B | major histocompatibility complex, class I, B | 0.0130136 |
| CAPNS1 | calpain, small subunit 1 | 0.0129651 |
| NPR2 | natriuretic peptide receptor 2 | 0.0129446 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | 0.0129307 |
| RPS15 | ribosomal protein S15 | 0.0128161 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SMAD3 | SMAD family member 3 | -0.126242 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.124117 |
| GOLGA4 | golgin A4 | -0.0964471 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0895823 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0865209 |
| PCBP2 | poly(rC) binding protein 2 | -0.082938 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0824541 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0799799 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0788606 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0747188 |
| RBM39 | RNA binding motif protein 39 | -0.0723682 |
| RPS2 | ribosomal protein S2 | -0.0706741 |
| USP34 | ubiquitin specific peptidase 34 | -0.069259 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0688963 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0668387 |
| EFNA5 | ephrin-A5 | -0.0667011 |
| PRELID2 | PRELI domain containing 2 | -0.0636228 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0618991 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0613877 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0570339 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0558275 |
| NDRG1 | N-myc downstream regulated 1 | -0.0506421 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0501929 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0488322 |
| JMJD1C | jumonji domain containing 1C | -0.0479366 |
| OGA | O-GlcNAcase | -0.0471946 |
| VEGFA | vascular endothelial growth factor A | -0.0470106 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0467154 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0458912 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0453555 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0452183 |
| RUNX1 | runt-related transcription factor 1 | -0.0451978 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0449909 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0447894 |
| ETV6 | ets variant 6 | -0.0441865 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0419497 |
| RPS6 | ribosomal protein S6 | -0.0414806 |
| KYNU | kynureninase | -0.0414228 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0405537 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0401446 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0396976 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0392957 |
| JAK1 | Janus kinase 1 | -0.0389042 |
| ATXN1 | ataxin 1 | -0.0385384 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0382035 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0380956 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0380346 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.0377792 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0371038 |
| DST | dystonin | -0.0367173 |
| HDAC9 | histone deacetylase 9 | -0.0364767 |
| FAM13A | family with sequence similarity 13, member A | -0.0363128 |
| B2M | beta-2-microglobulin | -0.0360798 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0359243 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0353195 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0348935 |
| LRRC49 | leucine rich repeat containing 49 | -0.0346681 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0345612 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0344914 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | -0.0341889 |
| ZNF638 | zinc finger protein 638 | -0.034014 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0338413 |
| ZNF292 | zinc finger protein 292 | -0.0333729 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | -0.0326601 |
| EGFR | epidermal growth factor receptor | -0.0321222 |
| CANX | calnexin | -0.032023 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0319822 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.0319686 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0317136 |
| TPR | translocated promoter region, nuclear basket protein | -0.0316527 |
| FAM107B | family with sequence similarity 107, member B | -0.0311318 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0310835 |
| STC1 | stanniocalcin 1 | -0.0309516 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0308408 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | -0.0306381 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | -0.0306019 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0305536 |
| MSN | moesin | -0.0304839 |
| ASPH | aspartate beta-hydroxylase | -0.0304158 |
| CLTC | clathrin, heavy chain (Hc) | -0.0303337 |
| PHF21A | PHD finger protein 21A | -0.0300002 |
| ANKRD36 | ankyrin repeat domain 36 | -0.0299322 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0298141 |
| LCOR | ligand dependent nuclear receptor corepressor | -0.0297667 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | -0.02973 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0295702 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0295025 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0291249 |
| NBAS | neuroblastoma amplified sequence | -0.0290626 |
| ANGPTL4 | angiopoietin-like 4 | -0.0289574 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0289061 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.028734 |
| XPO1 | exportin 1 | -0.0286121 |
| SPAG9 | sperm associated antigen 9 | -0.0285312 |
| UBXN4 | UBX domain protein 4 | -0.0284997 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0283758 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0283157 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0282629 |
| NAV2 | neuron navigator 2 | -0.0279417 |
| SUCO | SUN domain containing ossification factor | -0.0277051 |
