| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bisoprolol (hemifumarate) perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bisoprolol (hemifumarate)_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.0947609 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0505745 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0393743 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.031632 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0294427 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0261859 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0234027 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0233649 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.0233118 |
| RPL4 | ribosomal protein L4 | 0.0228215 |
| TUBB | tubulin, beta class I | 0.0218995 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0198895 |
| MKI67 | marker of proliferation Ki-67 | 0.0176751 |
| CAVIN1 | caveolae associated protein 1 | 0.0165781 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0154425 |
| TXNRD1 | thioredoxin reductase 1 | 0.0150393 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0150002 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.01435 |
| PKM | pyruvate kinase, muscle | 0.0142335 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0126653 |
| YBX3 | Y box binding protein 3 | 0.0123294 |
| RRM2 | ribonucleotide reductase M2 | 0.0122546 |
| UBE2S | ubiquitin-conjugating enzyme E2S | 0.0118204 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | 0.0116399 |
| HMGA1 | high mobility group AT-hook 1 | 0.0113381 |
| YBX1 | Y box binding protein 1 | 0.0109108 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0108114 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0107588 |
| FLNA | filamin A, alpha | 0.0105069 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0102223 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.00983497 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.00980849 |
| UCK2 | uridine-cytidine kinase 2 | 0.00969238 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.00958005 |
| PTBP1 | polypyrimidine tract binding protein 1 | 0.0094312 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.00937461 |
| PER1 | period circadian clock 1 | 0.00936843 |
| RPS2 | ribosomal protein S2 | 0.0090268 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.00889396 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | 0.00883795 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.00882782 |
| SDC4 | syndecan 4 | 0.0087579 |
| PFKP | phosphofructokinase, platelet | 0.00872433 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.00870328 |
| RAD21 | RAD21 homolog (S. pombe) | 0.00857229 |
| CCT3 | chaperonin containing TCP1, subunit 3 (gamma) | 0.00843112 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.008422 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.00839354 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.00831908 |
| ELL | elongation factor RNA polymerase II | 0.00821998 |
| TMEM123 | transmembrane protein 123 | 0.00799188 |
| CAPNS1 | calpain, small subunit 1 | 0.0078395 |
| TACC3 | transforming, acidic coiled-coil containing protein 3 | 0.00780572 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.00773693 |
| BAG6 | BCL2-associated athanogene 6 | 0.00773319 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.00760502 |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B | 0.0075853 |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 | 0.00753971 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 0.0075287 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.00743221 |
| AZIN1 | antizyme inhibitor 1 | 0.00735353 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.00734177 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.00732349 |
| KLF6 | Kruppel-like factor 6 | 0.00725386 |
| DOT1L | DOT1-like histone H3K79 methyltransferase | 0.00725332 |
| RAI1 | retinoic acid induced 1 | 0.0071999 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.00715896 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 0.00715096 |
| SF1 | splicing factor 1 | 0.00709931 |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | 0.00705146 |
| RPN2 | ribophorin II | 0.0069731 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.00694768 |
| KIF18B | kinesin family member 18B | 0.0069466 |
| PTMS | parathymosin | 0.00689561 |
| RPSA | ribosomal protein SA | 0.00686055 |
| WBP11 | WW domain binding protein 11 | 0.00680436 |
| ILF2 | interleukin enhancer binding factor 2 | 0.00677839 |
| PCGF2 | polycomb group ring finger 2 | 0.006722 |
| AREG | amphiregulin | 0.00672118 |
| CDC20 | cell division cycle 20 | 0.00668028 |
| ATXN2L | ataxin 2-like | 0.00665611 |
| VARS1 | valyl-tRNA synthetase 1 | 0.00664545 |
| UBE2C | ubiquitin-conjugating enzyme E2C | 0.00663464 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0065891 |
| NEK2 | NIMA-related kinase 2 | 0.00657156 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.00653102 |
| CEP170B | centrosomal protein 170B | 0.0065182 |
| RPL18 | ribosomal protein L18 | 0.00651766 |
| H1-0 | H1.0 linker histone | 0.00648406 |
| CMC2 | C-x(9)-C motif containing 2 | 0.00646665 |
| TUBG1 | tubulin, gamma 1 | 0.00643109 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | 0.00641832 |
| CDCA2 | cell division cycle associated 2 | 0.00641115 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.00640398 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.00639242 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.00633891 |
| NUP93 | nucleoporin 93kDa | 0.00630286 |
| FAM168A | family with sequence similarity 168, member A | 0.00629395 |
| CALM3 | calmodulin 3 (phosphorylase kinase, delta) | 0.0062776 |
| TCOF1 | Treacher Collins-Franceschetti syndrome 1 | 0.0062753 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.18902 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.151536 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.133296 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.131253 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.130153 |
| MT2A | metallothionein 2A | -0.11846 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.116917 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0985597 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0924924 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0919814 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0769211 |
| PARD3 | par-3 family cell polarity regulator | -0.0759952 |
| VIM | vimentin | -0.0703789 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0654037 |
| SVIL | supervillin | -0.0653401 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0585279 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0579137 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0555823 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0552837 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0552304 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.054772 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0541679 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0540562 |
| USP34 | ubiquitin specific peptidase 34 | -0.0535369 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0531942 |
| KYNU | kynureninase | -0.0516954 |
| EGFR | epidermal growth factor receptor | -0.0509097 |
| ACTG1 | actin gamma 1 | -0.050893 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0505844 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0503227 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0500188 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0497551 |
| PYGL | phosphorylase, glycogen, liver | -0.047504 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0462143 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0460638 |
| TMSB10 | thymosin beta 10 | -0.0451831 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0450434 |
| COPA | coatomer protein complex, subunit alpha | -0.0446263 |
| ASPH | aspartate beta-hydroxylase | -0.0444551 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0442305 |
| IGF2 | insulin-like growth factor 2 | -0.0439334 |
| DST | dystonin | -0.0436984 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0434235 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0433994 |
| CMIP | c-Maf inducing protein | -0.042844 |
| POTEF | POTE ankyrin domain family, member F | -0.0419157 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0415665 |
| GLIS3 | GLIS family zinc finger 3 | -0.0411347 |
| S100A6 | S100 calcium binding protein A6 | -0.040897 |
| FMNL2 | formin-like 2 | -0.0401631 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0400444 |
| OSMR | oncostatin M receptor | -0.0399888 |
| UTRN | utrophin | -0.0390974 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0386801 |
| HLA-B | major histocompatibility complex, class I, B | -0.0381081 |
| NEGR1 | neuronal growth regulator 1 | -0.0380317 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0375274 |
| PTK2 | protein tyrosine kinase 2 | -0.0361378 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0360918 |
| PDLIM5 | PDZ and LIM domain 5 | -0.035828 |
| ERBIN | erbb2 interacting protein | -0.0354044 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0352648 |
| FAM107B | family with sequence similarity 107, member B | -0.0350127 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0349644 |
| EHBP1 | EH domain binding protein 1 | -0.0347116 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0346463 |
| ATXN1 | ataxin 1 | -0.0344631 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0343114 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0340833 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0336222 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.033452 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.03324 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0332108 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0331366 |
| GLG1 | golgi glycoprotein 1 | -0.0330244 |
| GOLGA4 | golgin A4 | -0.0329377 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0327874 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0326481 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0320813 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0320503 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0319124 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0316783 |
| NUMB | numb homolog (Drosophila) | -0.0310716 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0306737 |
| MCL1 | myeloid cell leukemia 1 | -0.0304707 |
| SBF2 | SET binding factor 2 | -0.0299062 |
| EXOC6B | exocyst complex component 6B | -0.0298381 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0297278 |
| DENND4A | DENN/MADD domain containing 4A | -0.0293965 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.029314 |
| MYOF | myoferlin | -0.0293005 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0291065 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0289068 |
| BICC1 | BicC family RNA binding protein 1 | -0.0284885 |
| CUX1 | cut-like homeobox 1 | -0.0284818 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0284068 |
| NF1 | neurofibromin 1 | -0.0280245 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0279393 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0277023 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0276492 |
