| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bisoprolol (hemifumarate) perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
169 genes differentially expressed following the Bisoprolol (hemifumarate)_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.105927 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.101631 |
| VIM | vimentin | 0.0788767 |
| PKM | pyruvate kinase, muscle | 0.0703151 |
| TMSB10 | thymosin beta 10 | 0.066187 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0640869 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0572672 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.053167 |
| EZR | ezrin | 0.0513245 |
| SNX9 | sorting nexin 9 | 0.0505956 |
| FLNB | filamin B, beta | 0.0501937 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0500007 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0499177 |
| JMJD1C | jumonji domain containing 1C | 0.0496428 |
| EGR1 | early growth response 1 | 0.0437736 |
| CANX | calnexin | 0.0435173 |
| PCBP2 | poly(rC) binding protein 2 | 0.0434094 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0430845 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0410949 |
| AHNAK | AHNAK nucleoprotein | 0.040872 |
| PGK1 | phosphoglycerate kinase 1 | 0.0386699 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0373992 |
| RPS6 | ribosomal protein S6 | 0.0369409 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.035813 |
| NDRG1 | N-myc downstream regulated 1 | 0.0349714 |
| RPS16 | ribosomal protein S16 | 0.0332546 |
| RBM39 | RNA binding motif protein 39 | 0.0326917 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0323441 |
| ITGA6 | integrin, alpha 6 | 0.0310287 |
| AREG | amphiregulin | 0.0307713 |
| KRT8 | keratin 8, type II | 0.028613 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0255518 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0254698 |
| LDHA | lactate dehydrogenase A | 0.0249781 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0239005 |
| RPS3 | ribosomal protein S3 | 0.0237934 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0234564 |
| RPL23 | ribosomal protein L23 | 0.023255 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.022988 |
| RPLP1 | ribosomal protein, large, P1 | 0.0223655 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0220814 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0202295 |
| IGF2 | insulin-like growth factor 2 | 0.019726 |
| WASF2 | WAS protein family, member 2 | 0.0191004 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0189869 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0188873 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0181498 |
| SMYD3 | SET and MYND domain containing 3 | 0.0173109 |
| MT2A | metallothionein 2A | 0.0158335 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0154613 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0152127 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0150259 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0149088 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0142867 |
| FTL | ferritin, light polypeptide | 0.01247 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0124682 |
| RPS8 | ribosomal protein S8 | 0.011997 |
| LAMB3 | laminin, beta 3 | 0.0112378 |
| ANXA2 | annexin A2 | 0.011219 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0108203 |
| RPLP2 | ribosomal protein, large, P2 | 0.0107371 |
| UBE2K | ubiquitin-conjugating enzyme E2K | 0.010109 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.00974771 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.00959455 |
| LOC112694756 | uncharaterized LOC112694756 | 0.00915267 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | 0.00860787 |
| MYO5B | myosin VB | 0.00749636 |
| LMO7 | LIM domain 7 | 0.00746708 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.00734602 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.00722775 |
| RBM25 | RNA binding motif protein 25 | 0.00538684 |
| MYOF | myoferlin | 0.00472409 |
| KAT6B | K(lysine) acetyltransferase 6B | 0.00465697 |
| SETD5 | SET domain containing 5 | 0.00446007 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.00427499 |
| RACK1 | receptor for activated C kinase 1 | 0.00390204 |
| YBX3 | Y box binding protein 3 | 0.00378558 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.00365889 |
| RPL37 | ribosomal protein L37 | 0.00342183 |
| RPL7 | ribosomal protein L7 | 0.00292596 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.00280814 |
| FAT1 | FAT atypical cadherin 1 | 4.69006E-4 |
| RPL37A | ribosomal protein L37a | 4.18942E-4 |
| FNDC3B | fibronectin type III domain containing 3B | 3.41985E-4 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE10A | phosphodiesterase 10A | -0.123183 |
| EGFR | epidermal growth factor receptor | -0.0923492 |
| FN1 | fibronectin 1 | -0.0779831 |
| PHIP | pleckstrin homology domain interacting protein | -0.0718 |
| GPC6 | glypican 6 | -0.0669393 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0642697 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0550929 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0550141 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0537003 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0535611 |
| USP34 | ubiquitin specific peptidase 34 | -0.0503173 |
| DST | dystonin | -0.0495995 |
| ENO1 | enolase 1, (alpha) | -0.048383 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0439132 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0429294 |
| SLTM | SAFB-like, transcription modulator | -0.0427113 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0408013 |
| MYO6 | myosin VI | -0.0406111 |
| EFNA5 | ephrin-A5 | -0.0392772 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0363138 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0363007 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0346826 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0341583 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0336866 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0336451 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0328273 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0320319 |
| PTK2 | protein tyrosine kinase 2 | -0.030847 |
| MMP12 | matrix metallopeptidase 12 | -0.0299198 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0297071 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0290004 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.028418 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0276148 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0269174 |
| SBF2 | SET binding factor 2 | -0.0257613 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0244796 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0211484 |
| MCL1 | myeloid cell leukemia 1 | -0.0208702 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0208073 |
| FMNL2 | formin-like 2 | -0.0189568 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0176876 |
| ZNF292 | zinc finger protein 292 | -0.0174176 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0174173 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0168631 |
| UBE2Z | ubiquitin-conjugating enzyme E2Z | -0.0166414 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0158687 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.015839 |
| MYO1E | myosin IE | -0.0147323 |
| NF1 | neurofibromin 1 | -0.0138933 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0133598 |
| SP100 | SP100 nuclear antigen | -0.0127409 |
| YEATS2 | YEATS domain containing 2 | -0.0126237 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0124082 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0117119 |
| FNIP1 | folliculin interacting protein 1 | -0.0112604 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0108694 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0105114 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0104281 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0100759 |
| NPC1 | Niemann-Pick disease, type C1 | -0.009969 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.00922354 |
| NAV2 | neuron navigator 2 | -0.00912405 |
| TPM4 | tropomyosin 4 | -0.00911212 |
| AFF4 | AF4/FMR2 family, member 4 | -0.00909813 |
| STC1 | stanniocalcin 1 | -0.00842647 |
| OGA | O-GlcNAcase | -0.00770348 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.00769147 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.00707496 |
| ASPH | aspartate beta-hydroxylase | -0.00675951 |
| PUM2 | pumilio RNA-binding family member 2 | -0.00631741 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.00627147 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.00599459 |
| RPL26 | ribosomal protein L26 | -0.00589338 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.00584905 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.00492431 |
| STAG2 | stromal antigen 2 | -0.00474737 |
| CARD16 | caspase recruitment domain family, member 16 | -0.00394438 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.00382867 |
| TPD52 | tumor protein D52 | -0.00343034 |
| RPL19 | ribosomal protein L19 | -0.00214817 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.00190371 |
| CDK6 | cyclin-dependent kinase 6 | -0.00188591 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.00105579 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -3.21097E-4 |
| CD44 | CD44 molecule (Indian blood group) | -4.88962E-5 |
