| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bisoprolol (hemifumarate) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bisoprolol (hemifumarate)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0357856 |
| TBC1D12 | TBC1 domain family, member 12 | 0.0238722 |
| UPP1 | uridine phosphorylase 1 | 0.0204248 |
| ANXA5 | annexin A5 | 0.0193352 |
| NID1 | nidogen 1 | 0.0190409 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0181857 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0177134 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.01759 |
| FLNA | filamin A, alpha | 0.0164417 |
| HDLBP | high density lipoprotein binding protein | 0.0163795 |
| MYO10 | myosin X | 0.0162816 |
| HBP1 | HMG-box transcription factor 1 | 0.0157627 |
| TFRC | transferrin receptor | 0.0154038 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0153056 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 0.015181 |
| NUP155 | nucleoporin 155kDa | 0.0150242 |
| FLII | flightless I homolog (Drosophila) | 0.0146013 |
| UGGT1 | UDP-glucose glycoprotein glucosyltransferase 1 | 0.0144062 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0142537 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0140819 |
| HYOU1 | hypoxia up-regulated 1 | 0.0138304 |
| NCKAP1 | NCK-associated protein 1 | 0.0138127 |
| PCDH18 | protocadherin 18 | 0.0137845 |
| ATP11B | ATPase, class VI, type 11B | 0.0136664 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.01337 |
| RNF10 | ring finger protein 10 | 0.0132225 |
| CCNYL1 | cyclin Y-like 1 | 0.0132168 |
| TCF20 | transcription factor 20 (AR1) | 0.0131581 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0131403 |
| H1-4 | H1.4 linker histone, cluster member | 0.013111 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0130886 |
| MARK2 | MAP/microtubule affinity-regulating kinase 2 | 0.0130885 |
| CLDND1 | claudin domain containing 1 | 0.0130417 |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 | 0.0129696 |
| CDK17 | cyclin-dependent kinase 17 | 0.0129664 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0129315 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0129263 |
| SPOPL | speckle-type POZ protein-like | 0.0128878 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0128393 |
| CIP2A | cellular inhibitor of PP2A | 0.0128227 |
| WDR1 | WD repeat domain 1 | 0.0127645 |
| EXTL3 | exostosin-like glycosyltransferase 3 | 0.0127173 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0127127 |
| TOB2 | transducer of ERBB2, 2 | 0.0126355 |
| CCPG1 | cell cycle progression 1 | 0.0125854 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0124375 |
| HDAC3 | histone deacetylase 3 | 0.0124162 |
| AKIRIN1 | akirin 1 | 0.0123323 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0123135 |
| NUDCD3 | NudC domain containing 3 | 0.0123072 |
| INCENP | inner centromere protein antigens 135/155kDa | 0.012214 |
| AGO1 | argonaute RISC catalytic component 1 | 0.0121854 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | 0.0121108 |
| KDM1A | lysine (K)-specific demethylase 1A | 0.0120231 |
| RALGAPB | Ral GTPase activating protein, beta subunit (non-catalytic) | 0.0120137 |
| GANAB | glucosidase, alpha; neutral AB | 0.0119627 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0119547 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0119367 |
| TMEM248 | transmembrane protein 248 | 0.0119311 |
| CDC42 | cell division cycle 42 | 0.0119174 |
| TRIM33 | tripartite motif containing 33 | 0.0118662 |
| LSM8 | LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.0118385 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0117556 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0116971 |
| SFT2D2 | SFT2 domain containing 2 | 0.0115761 |
| STX16 | syntaxin 16 | 0.0115191 |
| CMTM4 | CKLF-like MARVEL transmembrane domain containing 4 | 0.0114858 |
| PAIP1 | poly(A) binding protein interacting protein 1 | 0.0114394 |
| SERGEF | secretion regulating guanine nucleotide exchange factor | 0.0114301 |
| UBE2A | ubiquitin-conjugating enzyme E2A | 0.0113382 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0113347 |
| NIBAN1 | niban apoptosis regulator 1 | 0.01131 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0112962 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0112453 |
| LEMD3 | LEM domain containing 3 | 0.0111842 |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) | 0.0111401 |
| EXOSC8 | exosome component 8 | 0.0111346 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 0.0110967 |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits | 0.011095 |
| BNC2 | basonuclin 2 | 0.0110591 |
| TNIK | TRAF2 and NCK interacting kinase | 0.011043 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0110327 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.0110166 |
| SNX2 | sorting nexin 2 | 0.011005 |
| ACVR2A | activin A receptor, type IIA | 0.0110041 |
| STRN | striatin, calmodulin binding protein | 0.0109627 |
| CLPTM1 | cleft lip and palate associated transmembrane protein 1 | 0.0109461 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0109419 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0109417 |
| SIN3A | SIN3 transcription regulator family member A | 0.0109383 |
| LDHD | lactate dehydrogenase D | 0.0109005 |
| FLCN | folliculin | 0.0108972 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.0108827 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) | 0.0108522 |
| NARS2 | asparaginyl-tRNA synthetase 2, mitochondrial (putative) | 0.0108488 |
| DSPP | dentin sialophosphoprotein | 0.0108484 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0108353 |
| TNPO1 | transportin 1 | 0.0108098 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0107919 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.0107687 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.166439 |
| VIM | vimentin | -0.166358 |
| TMSB10 | thymosin beta 10 | -0.160831 |
| COL11A1 | collagen, type XI, alpha 1 | -0.142901 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.118816 |
| GPC3 | glypican 3 | -0.114478 |
| PTMA | prothymosin, alpha | -0.113082 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.10072 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0951807 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0873777 |
| PCDH9 | protocadherin 9 | -0.0822774 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0816075 |
| CADM2 | cell adhesion molecule 2 | -0.0737524 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0732958 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0719219 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0718092 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0717742 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0698012 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.068535 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0664447 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0662479 |
| RPS8 | ribosomal protein S8 | -0.0661819 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -0.0658257 |
| RPL23 | ribosomal protein L23 | -0.0647566 |
| RPL37A | ribosomal protein L37a | -0.0608595 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0591878 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0588546 |
| RPS6 | ribosomal protein S6 | -0.0580819 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0568516 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0562154 |
| GNAS | GNAS complex locus | -0.0558852 |
| RPLP1 | ribosomal protein, large, P1 | -0.0557451 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0549025 |
| PEG10 | paternally expressed 10 | -0.054364 |
| TMSB4X | thymosin beta 4, X-linked | -0.0532486 |
| COL5A2 | collagen, type V, alpha 2 | -0.0525115 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0516039 |
| PHIP | pleckstrin homology domain interacting protein | -0.0508612 |
| ACTG1 | actin gamma 1 | -0.0491039 |
| JMJD1C | jumonji domain containing 1C | -0.0481035 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0477584 |
| RPL35A | ribosomal protein L35a | -0.0476785 |
| SPAG9 | sperm associated antigen 9 | -0.0472588 |
| LRRC4C | leucine rich repeat containing 4C | -0.0470951 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0458982 |
| RPL9 | ribosomal protein L9 | -0.0458958 |
| PLPP1 | phospholipid phosphatase 1 | -0.0457182 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0456786 |
| MAP4 | microtubule-associated protein 4 | -0.0450492 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0448729 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0448265 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.044699 |
| COL1A2 | collagen, type I, alpha 2 | -0.0441617 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0438108 |
| HMGB1 | high mobility group box 1 | -0.043763 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0432048 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.0431868 |
| CENPF | centromere protein F, 350/400kDa | -0.0429132 |
| NRG1 | neuregulin 1 | -0.042727 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0423377 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0416147 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.041351 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0411961 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0401679 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0401032 |
| RPS16 | ribosomal protein S16 | -0.0399195 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0397231 |
| RPS12 | ribosomal protein S12 | -0.0387665 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0387604 |
| SNX6 | sorting nexin 6 | -0.0386447 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.038431 |
| METAP2 | methionyl aminopeptidase 2 | -0.0382137 |
| MKI67 | marker of proliferation Ki-67 | -0.0378505 |
| PFN1 | profilin 1 | -0.0376753 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0367429 |
| ANXA2 | annexin A2 | -0.0367001 |
| RPS19 | ribosomal protein S19 | -0.0366705 |
| RPS3 | ribosomal protein S3 | -0.0360743 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0358507 |
| RPL34 | ribosomal protein L34 | -0.0353713 |
| PTK2 | protein tyrosine kinase 2 | -0.0353642 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0353259 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | -0.035237 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0351737 |
| FBXO11 | F-box protein 11 | -0.0351571 |
| ENAH | enabled homolog (Drosophila) | -0.0350885 |
| RPL37 | ribosomal protein L37 | -0.0347493 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0346188 |
| FTL | ferritin, light polypeptide | -0.03455 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0340592 |
| RAD51B | RAD51 paralog B | -0.0339082 |
| RPL12 | ribosomal protein L12 | -0.0338429 |
| NOP58 | NOP58 ribonucleoprotein | -0.0337279 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0336587 |
| RPL11 | ribosomal protein L11 | -0.0332594 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0331488 |
| RPL5 | ribosomal protein L5 | -0.0330188 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0329696 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0328268 |
| B2M | beta-2-microglobulin | -0.0325736 |
