| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bisoprolol (hemifumarate) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bisoprolol (hemifumarate)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.121197 |
| ACTN4 | actinin, alpha 4 | 0.0907648 |
| RPS16 | ribosomal protein S16 | 0.0883953 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0761508 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0673014 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0636182 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0529648 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0519001 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0514219 |
| PLEKHG2 | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 | 0.0454415 |
| SMYD3 | SET and MYND domain containing 3 | 0.0451528 |
| ZNF780B | zinc finger protein 780B | 0.0439351 |
| RPS24 | ribosomal protein S24 | 0.0432789 |
| SAMD4B | sterile alpha motif domain containing 4B | 0.0431162 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 0.0407133 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0402798 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0376717 |
| ASPH | aspartate beta-hydroxylase | 0.0371595 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0358744 |
| RPLP2 | ribosomal protein, large, P2 | 0.0354309 |
| CARD18 | caspase recruitment domain family, member 18 | 0.0352423 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0333996 |
| RPLP1 | ribosomal protein, large, P1 | 0.0327169 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0316938 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0315955 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0314386 |
| CD44 | CD44 molecule (Indian blood group) | 0.0313817 |
| VMP1 | vacuole membrane protein 1 | 0.0313077 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0309836 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0300738 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.029527 |
| EFNA5 | ephrin-A5 | 0.0294968 |
| EXT1 | exostosin glycosyltransferase 1 | 0.029443 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0284401 |
| BCL2L1 | BCL2-like 1 | 0.0281943 |
| ITGB5 | integrin, beta 5 | 0.0264895 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0260719 |
| RASAL2 | RAS protein activator like 2 | 0.0258814 |
| OSMR | oncostatin M receptor | 0.0256857 |
| KLF6 | Kruppel-like factor 6 | 0.0255436 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0255155 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0253659 |
| ATP9B | ATPase, class II, type 9B | 0.0249702 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0248703 |
| NUP98 | nucleoporin 98kDa | 0.0245984 |
| FHL2 | four and a half LIM domains 2 | 0.0245299 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0245214 |
| EXOC6B | exocyst complex component 6B | 0.0244931 |
| ATG10 | autophagy related 10 | 0.0243175 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0242907 |
| RPL36A | ribosomal protein L36a | 0.0240695 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0240194 |
| SATB2 | SATB homeobox 2 | 0.0240084 |
| DNMBP | dynamin binding protein | 0.023832 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0237267 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0236812 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0236798 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0229295 |
| APP | amyloid beta (A4) precursor protein | 0.0225094 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0224598 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.022346 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.0223045 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0222048 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.0221583 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0216141 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0215423 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0213935 |
| RPL38 | ribosomal protein L38 | 0.0210815 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.021015 |
| BMERB1 | bMERB domain containing 1 | 0.0210034 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0206661 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0203427 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.02025 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0201894 |
| CAVIN1 | caveolae associated protein 1 | 0.0201345 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0198828 |
| AHNAK | AHNAK nucleoprotein | 0.0198706 |
| WWOX | WW domain containing oxidoreductase | 0.0198206 |
| PRELID2 | PRELI domain containing 2 | 0.0197061 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.0195943 |
| SMAD3 | SMAD family member 3 | 0.0195142 |
| BMP6 | bone morphogenetic protein 6 | 0.0194044 |
| EXOC4 | exocyst complex component 4 | 0.0193952 |
| STK4 | serine/threonine kinase 4 | 0.0192854 |
| MCL1 | myeloid cell leukemia 1 | 0.0192427 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0191207 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0191153 |
| AOPEP | aminopeptidase O (putative) | 0.0189604 |
| TRIM66 | tripartite motif containing 66 | 0.0188408 |
| CDK13 | cyclin-dependent kinase 13 | 0.0188184 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0188085 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0187642 |
| MAP3K10 | mitogen-activated protein kinase kinase kinase 10 | 0.0185521 |
| EGR1 | early growth response 1 | 0.0184305 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0184038 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0183804 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0182895 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0179904 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0177121 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0174952 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.160576 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.153254 |
| PTMA | prothymosin, alpha | -0.148158 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.147708 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.116592 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.114184 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.103589 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.101484 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0814096 |
| FBL | fibrillarin | -0.0718038 |
| S100A6 | S100 calcium binding protein A6 | -0.0643544 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0619586 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0613348 |
| ZFP36 | ZFP36 ring finger protein | -0.0540666 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0525793 |
| LDHA | lactate dehydrogenase A | -0.0523588 |
| YBX1 | Y box binding protein 1 | -0.0506486 |
| FTL | ferritin, light polypeptide | -0.0503153 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0490511 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0476551 |
| FMNL2 | formin-like 2 | -0.0467507 |
| HMGA1 | high mobility group AT-hook 1 | -0.0457898 |
| ADM | adrenomedullin | -0.0449025 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0448239 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0438937 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0429229 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0414517 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0408764 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0404435 |
| PFN1 | profilin 1 | -0.0403529 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0402 |
| PCBP2 | poly(rC) binding protein 2 | -0.0377335 |
| GOLGA4 | golgin A4 | -0.0343263 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0336315 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0330299 |
| TMEM123 | transmembrane protein 123 | -0.0329608 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0326589 |
| CD109 | CD109 molecule | -0.031573 |
| PKM | pyruvate kinase, muscle | -0.0312117 |
| WASF2 | WAS protein family, member 2 | -0.0306795 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.029823 |
| SNX14 | sorting nexin 14 | -0.0294389 |
| CENPF | centromere protein F, 350/400kDa | -0.0294184 |
| FOSL1 | FOS-like antigen 1 | -0.0292145 |
| POTEF | POTE ankyrin domain family, member F | -0.0289825 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0289703 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0289606 |
| SEPTIN7 | septin 7 | -0.0283132 |
| RPS6 | ribosomal protein S6 | -0.0274887 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.026662 |
| CCNL1 | cyclin L1 | -0.0265264 |
| TMSB10 | thymosin beta 10 | -0.0264938 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | -0.0260259 |
| SNX3 | sorting nexin 3 | -0.0259001 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0253535 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0248255 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0245192 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | -0.0243508 |
| DSTN | destrin (actin depolymerizing factor) | -0.0242467 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.024121 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0240497 |
| XPO1 | exportin 1 | -0.0239694 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0235007 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0234812 |
| UBC | ubiquitin C | -0.0228386 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0226992 |
| CANX | calnexin | -0.0226436 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0219929 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0216981 |
| TPM2 | tropomyosin 2 (beta) | -0.0216157 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0213723 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0212694 |
| SET | SET nuclear proto-oncogene | -0.021257 |
| SRP54 | signal recognition particle 54kDa | -0.0211054 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0210041 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.020924 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0207022 |
| GSPT1 | G1 to S phase transition 1 | -0.0206857 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0206392 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0205134 |
| RPL23 | ribosomal protein L23 | -0.0201299 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0197701 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0197154 |
| RDX | radixin | -0.0196976 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0189079 |
| PKN2 | protein kinase N2 | -0.0186106 |
| MYOF | myoferlin | -0.0185341 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | -0.0184289 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0184076 |
| CBX3 | chromobox homolog 3 | -0.0184067 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0181621 |
| ARRDC3 | arrestin domain containing 3 | -0.0181538 |
| TPD52 | tumor protein D52 | -0.0180879 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.0180814 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0179958 |
| SETD5 | SET domain containing 5 | -0.0178198 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0178093 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.017596 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0175227 |
| STC2 | stanniocalcin 2 | -0.0173829 |
