| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bisoprolol (hemifumarate) perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bisoprolol (hemifumarate)_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.12204 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.110911 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0985768 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0785952 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0781246 |
| TSC22D2 | TSC22 domain family, member 2 | 0.063973 |
| LAMB3 | laminin, beta 3 | 0.0607354 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0605983 |
| KRT17 | keratin 17, type I | 0.0594626 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0566849 |
| PLAT | plasminogen activator, tissue | 0.0559771 |
| AHNAK | AHNAK nucleoprotein | 0.0536733 |
| TGM2 | transglutaminase 2 | 0.0524716 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0518109 |
| PGK1 | phosphoglycerate kinase 1 | 0.0506513 |
| KRT18 | keratin 18, type I | 0.0504931 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0460332 |
| NAV2 | neuron navigator 2 | 0.0429575 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0410613 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0398069 |
| KRT19 | keratin 19, type I | 0.039156 |
| SDC4 | syndecan 4 | 0.0389108 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0370353 |
| HLA-A | major histocompatibility complex, class I, A | 0.0364385 |
| TXNIP | thioredoxin interacting protein | 0.0363901 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0355764 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0352775 |
| ANLN | anillin, actin binding protein | 0.0350648 |
| CALR | calreticulin | 0.0341825 |
| TOP1 | topoisomerase (DNA) I | 0.0336307 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0330372 |
| MATR3 | matrin 3 | 0.0327372 |
| ARRDC3 | arrestin domain containing 3 | 0.0323431 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0322688 |
| TC2N | tandem C2 domains, nuclear | 0.0321837 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0308891 |
| WWC1 | WW and C2 domain containing 1 | 0.0307516 |
| USP3 | ubiquitin specific peptidase 3 | 0.0307268 |
| XPO1 | exportin 1 | 0.0305213 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0297717 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0297641 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0296984 |
| LDHA | lactate dehydrogenase A | 0.0296777 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0296188 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0292667 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0287263 |
| TMEM123 | transmembrane protein 123 | 0.0286448 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0283864 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0280809 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0280534 |
| CDCP1 | CUB domain containing protein 1 | 0.0280282 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0272726 |
| MKI67 | marker of proliferation Ki-67 | 0.0271853 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0268058 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0265671 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0265029 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0262132 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.026048 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0256138 |
| LAMA5 | laminin, alpha 5 | 0.0255355 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0252729 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0249024 |
| LATS2 | large tumor suppressor kinase 2 | 0.0248761 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0243637 |
| TXNRD1 | thioredoxin reductase 1 | 0.0241514 |
| EZR | ezrin | 0.0239916 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0238381 |
| KRT8 | keratin 8, type II | 0.0237962 |
| AFAP1 | actin filament associated protein 1 | 0.0237293 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.023698 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0236819 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0236625 |
| ATP13A3 | ATPase type 13A3 | 0.0233099 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.023299 |
| RTN4 | reticulon 4 | 0.0230892 |
| CANX | calnexin | 0.0229736 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | 0.0222069 |
| PLEC | plectin | 0.022126 |
| OGA | O-GlcNAcase | 0.0216701 |
| HLA-B | major histocompatibility complex, class I, B | 0.0215817 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0215386 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.021528 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0214216 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0213803 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0212939 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0211669 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | 0.0209269 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0208588 |
| CENPF | centromere protein F, 350/400kDa | 0.0207836 |
| HLA-C | major histocompatibility complex, class I, C | 0.0207524 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0205746 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0205603 |
| RNF145 | ring finger protein 145 | 0.0205389 |
| NCKAP1 | NCK-associated protein 1 | 0.0204081 |
| TUBB | tubulin, beta class I | 0.0203374 |
| WDR45B | WD repeat domain 45B | 0.0202651 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0202613 |
| KLF10 | Kruppel-like factor 10 | 0.0202609 |
| GSN | gelsolin | 0.0201537 |
| TFG | TRK-fused gene | 0.020096 |
| Symbol | Name | Standardized Value |
|---|---|---|
| INTS6 | integrator complex subunit 6 | -0.168513 |
| LMO7 | LIM domain 7 | -0.149971 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.110397 |
| FN1 | fibronectin 1 | -0.0976695 |
| PLSCR1 | phospholipid scramblase 1 | -0.0938238 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0895307 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0886016 |
| TJP1 | tight junction protein 1 | -0.0854365 |
| SYT14 | synaptotagmin XIV | -0.0812296 |
| PDLIM5 | PDZ and LIM domain 5 | -0.080989 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0800398 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0788831 |
| HDAC9 | histone deacetylase 9 | -0.0780572 |
| TMSB10 | thymosin beta 10 | -0.07706 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0762307 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0758365 |
| RPS3 | ribosomal protein S3 | -0.0725952 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0654032 |
| VCL | vinculin | -0.0638592 |
| MYO6 | myosin VI | -0.0631978 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0628964 |
| ACTG1 | actin gamma 1 | -0.0622858 |
| EGR1 | early growth response 1 | -0.0618375 |
| RNF213 | ring finger protein 213 | -0.0617597 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0611396 |
| RPS8 | ribosomal protein S8 | -0.0610771 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0598941 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0583314 |
| MUC4 | mucin 4, cell surface associated | -0.0577333 |
| MYO1E | myosin IE | -0.0548493 |
| SVIL | supervillin | -0.0547007 |
| RPL23 | ribosomal protein L23 | -0.0545663 |
| RIGI | RNA sensor RIG-I | -0.0544276 |
| MUC16 | mucin 16, cell surface associated | -0.0543941 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0537061 |
| RCOR1 | REST corepressor 1 | -0.0526191 |
| ETV6 | ets variant 6 | -0.0525289 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0519029 |
| RAD51B | RAD51 paralog B | -0.0513372 |
| GOLGB1 | golgin B1 | -0.0511199 |
| RASAL2 | RAS protein activator like 2 | -0.0510221 |
| CD44 | CD44 molecule (Indian blood group) | -0.0475329 |
| HMGA2 | high mobility group AT-hook 2 | -0.0467663 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0464005 |
| RPS6 | ribosomal protein S6 | -0.046069 |
| MT2A | metallothionein 2A | -0.046029 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.045968 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0457044 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0447737 |
| RPL37A | ribosomal protein L37a | -0.0442148 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0439432 |
| ANXA2 | annexin A2 | -0.0437606 |
| SIK3 | SIK family kinase 3 | -0.0435636 |
| ZDHHC13 | zinc finger, DHHC-type containing 13 | -0.0425697 |
| ERBIN | erbb2 interacting protein | -0.0417202 |
| EMP1 | epithelial membrane protein 1 | -0.0415474 |
| RPS19 | ribosomal protein S19 | -0.0414734 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0414432 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0412614 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0408989 |
| PTMA | prothymosin, alpha | -0.0404954 |
| ASPH | aspartate beta-hydroxylase | -0.0396308 |
| AEBP2 | AE binding protein 2 | -0.03958 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0388296 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0387845 |
| VMP1 | vacuole membrane protein 1 | -0.0383541 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0382986 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0382596 |
| RPL9 | ribosomal protein L9 | -0.0380552 |
| RPL31 | ribosomal protein L31 | -0.0375247 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.037429 |
| SQSTM1 | sequestosome 1 | -0.0370024 |
| GNAS | GNAS complex locus | -0.0364947 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.036378 |
| RACK1 | receptor for activated C kinase 1 | -0.0360563 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0357787 |
| EXOC4 | exocyst complex component 4 | -0.035538 |
| IFI44L | interferon-induced protein 44-like | -0.0355162 |
| IFI44 | interferon-induced protein 44 | -0.0354887 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0353561 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0353108 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0349397 |
| UBAP2 | ubiquitin associated protein 2 | -0.0349035 |
| MX1 | MX dynamin-like GTPase 1 | -0.0348819 |
| THRB | thyroid hormone receptor, beta | -0.034772 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | -0.0346964 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0345834 |
| EHBP1 | EH domain binding protein 1 | -0.0343575 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0339828 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.033711 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | -0.0336552 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0333067 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0328467 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0328156 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0326504 |
| DAPK1 | death-associated protein kinase 1 | -0.03208 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | -0.0320621 |
| RPL12 | ribosomal protein L12 | -0.0319224 |
| TLE4 | transducin-like enhancer of split 4 | -0.0315637 |
| FMNL2 | formin-like 2 | -0.0315283 |
