| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bisoprolol (hemifumarate) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bisoprolol (hemifumarate)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.224638 |
| COL1A1 | collagen, type I, alpha 1 | 0.0910164 |
| CDH13 | cadherin 13 | 0.080522 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0800331 |
| HLA-B | major histocompatibility complex, class I, B | 0.0787937 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0756198 |
| COL1A2 | collagen, type I, alpha 2 | 0.0741181 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0697928 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0622299 |
| MMP12 | matrix metallopeptidase 12 | 0.0594084 |
| COL5A1 | collagen, type V, alpha 1 | 0.0591925 |
| EML5 | echinoderm microtubule associated protein like 5 | 0.0588183 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0582058 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0563736 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0561794 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0559516 |
| LOXL2 | lysyl oxidase-like 2 | 0.055528 |
| TPM1 | tropomyosin 1 (alpha) | 0.0542798 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0527914 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0523882 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0489717 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0487699 |
| CADM1 | cell adhesion molecule 1 | 0.0473278 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0467621 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0462577 |
| INHBA | inhibin, beta A | 0.0453232 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.045299 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0438481 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0422279 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0405389 |
| NAV1 | neuron navigator 1 | 0.0393788 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0387626 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0386288 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0359643 |
| HLA-A | major histocompatibility complex, class I, A | 0.0359516 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0358643 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0347903 |
| CA12 | carbonic anhydrase XII | 0.0340525 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0332356 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0323353 |
| MYOF | myoferlin | 0.0320721 |
| B2M | beta-2-microglobulin | 0.031897 |
| IL1B | interleukin 1, beta | 0.0314383 |
| COLEC10 | collectin sub-family member 10 (C-type lectin) | 0.0313213 |
| HDAC9 | histone deacetylase 9 | 0.0299882 |
| MTSS1 | metastasis suppressor 1 | 0.0296516 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0290519 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0289864 |
| MMP2 | matrix metallopeptidase 2 | 0.028211 |
| RNF213 | ring finger protein 213 | 0.0275462 |
| EGR1 | early growth response 1 | 0.0273543 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0270889 |
| CD109 | CD109 molecule | 0.0270605 |
| VEGFA | vascular endothelial growth factor A | 0.0267905 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0257963 |
| APCDD1L | adenomatosis polyposis coli down-regulated 1-like | 0.025548 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0255312 |
| FHIT | fragile histidine triad | 0.0253016 |
| FBXO32 | F-box protein 32 | 0.0252229 |
| TMEM178B | transmembrane protein 178B | 0.0250299 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0249094 |
| RND3 | Rho family GTPase 3 | 0.0245388 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0242914 |
| JUN | jun proto-oncogene | 0.0239866 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0237909 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.023778 |
| TNS3 | tensin 3 | 0.0237281 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0237084 |
| RAI14 | retinoic acid induced 14 | 0.0236185 |
| FAT1 | FAT atypical cadherin 1 | 0.0235113 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0234968 |
| EGFR | epidermal growth factor receptor | 0.0230347 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0226541 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0221552 |
| HLA-E | major histocompatibility complex, class I, E | 0.0220091 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0218626 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0216128 |
| COL5A2 | collagen, type V, alpha 2 | 0.0215927 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0214439 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0213763 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0213293 |
| SQSTM1 | sequestosome 1 | 0.0209799 |
| AGBL1 | ATP/GTP binding protein-like 1 | 0.0209182 |
| HLA-C | major histocompatibility complex, class I, C | 0.0207522 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0207493 |
| CLIC4 | chloride intracellular channel 4 | 0.0204216 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0202295 |
| DST | dystonin | 0.0202291 |
| TWIST2 | twist family bHLH transcription factor 2 | 0.0200927 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0199039 |
| NRP1 | neuropilin 1 | 0.0197707 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0197354 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0195505 |
| RIGI | RNA sensor RIG-I | 0.0193393 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0191325 |
| GLIS3 | GLIS family zinc finger 3 | 0.0191055 |
| STC2 | stanniocalcin 2 | 0.0190886 |
| COL27A1 | collagen, type XXVII, alpha 1 | 0.0187573 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0186335 |
| SP100 | SP100 nuclear antigen | 0.0185646 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.171826 |
| MT2A | metallothionein 2A | -0.148782 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.135086 |
| GOLGA4 | golgin A4 | -0.0509588 |
| ZNF292 | zinc finger protein 292 | -0.0507313 |
| CENPF | centromere protein F, 350/400kDa | -0.0477328 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0441174 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0435343 |
| RBM39 | RNA binding motif protein 39 | -0.041282 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0405317 |
| CD44 | CD44 molecule (Indian blood group) | -0.0387929 |
| DIAPH3 | diaphanous-related formin 3 | -0.035542 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0348281 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0347029 |
| SETD5 | SET domain containing 5 | -0.0346211 |
| PGK1 | phosphoglycerate kinase 1 | -0.0343668 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0338654 |
| RPLP1 | ribosomal protein, large, P1 | -0.0335241 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0323896 |
| TMSB10 | thymosin beta 10 | -0.0298305 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0296652 |
| COPA | coatomer protein complex, subunit alpha | -0.0291522 |
| TPX2 | TPX2, microtubule-associated | -0.0289405 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0289138 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0283251 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0279815 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0273301 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0271922 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0271252 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.026928 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0268926 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0267962 |
| SEPTIN7 | septin 7 | -0.0258135 |
| MKI67 | marker of proliferation Ki-67 | -0.0258047 |
| ECT2 | epithelial cell transforming 2 | -0.0256178 |
| TMEM39A | transmembrane protein 39A | -0.0251823 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.024999 |
| CENPE | centromere protein E, 312kDa | -0.024955 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0246123 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0245653 |
| COG6 | component of oligomeric golgi complex 6 | -0.0245106 |
| KIF20B | kinesin family member 20B | -0.0241293 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0240195 |
| TFG | TRK-fused gene | -0.023911 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0236572 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.023483 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.0234472 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.023284 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0229732 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0226542 |
| SBF2 | SET binding factor 2 | -0.0222879 |
| NPTN | neuroplastin | -0.0220088 |
| RPS19 | ribosomal protein S19 | -0.0217228 |
| GPSM2 | G-protein signaling modulator 2 | -0.0213819 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0212786 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0212381 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0211318 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0210628 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0209631 |
| ZNF644 | zinc finger protein 644 | -0.0206108 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0205859 |
| TBC1D23 | TBC1 domain family, member 23 | -0.0202222 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.020167 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0201497 |
| KIF4A | kinesin family member 4A | -0.0201129 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0200907 |
| VMP1 | vacuole membrane protein 1 | -0.0199624 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0199124 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0197919 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0196565 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0196138 |
| PRC1 | protein regulator of cytokinesis 1 | -0.0194795 |
| VCL | vinculin | -0.0194184 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0193971 |
| RLIM | ring finger protein, LIM domain interacting | -0.0193488 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | -0.0190101 |
| CLINT1 | clathrin interactor 1 | -0.0188832 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0186053 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0185928 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0185882 |
| FKBP1A | FK506 binding protein 1A, 12kDa | -0.018548 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0185386 |
| PCBP2 | poly(rC) binding protein 2 | -0.0182435 |
| RTN4 | reticulon 4 | -0.0181495 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0181234 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | -0.0180923 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0180168 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0179364 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0178826 |
| PTMA | prothymosin, alpha | -0.0178598 |
| ACTN4 | actinin, alpha 4 | -0.0178424 |
| MSN | moesin | -0.0178329 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0178302 |
| SCFD2 | sec1 family domain containing 2 | -0.0176179 |
| ETNK1 | ethanolamine kinase 1 | -0.0175516 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | -0.0175363 |
| LDHA | lactate dehydrogenase A | -0.0174505 |
| TMF1 | TATA element modulatory factor 1 | -0.0173675 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0172242 |
| YBX1 | Y box binding protein 1 | -0.0171296 |
