| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bisoprolol (hemifumarate) perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bisoprolol (hemifumarate)_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VGF | VGF nerve growth factor inducible | 0.110409 |
| PDE10A | phosphodiesterase 10A | 0.108952 |
| TENM1 | teneurin transmembrane protein 1 | 0.0715732 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0542557 |
| CENPF | centromere protein F, 350/400kDa | 0.0501279 |
| PITPNM2 | phosphatidylinositol transfer protein, membrane-associated 2 | 0.0453328 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0399514 |
| MKI67 | marker of proliferation Ki-67 | 0.0374494 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.033723 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0294936 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0278864 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0278658 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0273899 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.026936 |
| IGF2 | insulin-like growth factor 2 | 0.0269324 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0239474 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0237834 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0233814 |
| GRAMD4 | GRAM domain containing 4 | 0.0230206 |
| FTL | ferritin, light polypeptide | 0.0229412 |
| PTMA | prothymosin, alpha | 0.0228509 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0219597 |
| RPL23 | ribosomal protein L23 | 0.0210753 |
| FAT1 | FAT atypical cadherin 1 | 0.0207688 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0205079 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0204307 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0193487 |
| RTN4 | reticulon 4 | 0.0187416 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0186786 |
| SASH1 | SAM and SH3 domain containing 1 | 0.0181618 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0180288 |
| CALCA | calcitonin-related polypeptide alpha | 0.0180064 |
| DIAPH3 | diaphanous-related formin 3 | 0.0179399 |
| CEP70 | centrosomal protein 70kDa | 0.017892 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0177462 |
| TUBB | tubulin, beta class I | 0.0176957 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0174828 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | 0.0174254 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0173308 |
| IRF2BPL | interferon regulatory factor 2 binding protein-like | 0.0173223 |
| PRC1 | protein regulator of cytokinesis 1 | 0.0169719 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0166356 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0164438 |
| SEZ6L2 | seizure related 6 homolog (mouse)-like 2 | 0.0163356 |
| PDS5B | PDS5 cohesin associated factor B | 0.0163171 |
| CENPE | centromere protein E, 312kDa | 0.0160621 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0155395 |
| CLASP2 | cytoplasmic linker associated protein 2 | 0.0155019 |
| RACGAP1 | Rac GTPase activating protein 1 | 0.0153419 |
| RPS10 | ribosomal protein S10 | 0.0152925 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0152349 |
| TXNIP | thioredoxin interacting protein | 0.0152328 |
| KIF4A | kinesin family member 4A | 0.0152078 |
| MYEF2 | myelin expression factor 2 | 0.0151859 |
| TTK | TTK protein kinase | 0.0150556 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) | 0.0150235 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0149572 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.014847 |
| PER1 | period circadian clock 1 | 0.0147643 |
| RPS15 | ribosomal protein S15 | 0.0145055 |
| DNAH5 | dynein, axonemal, heavy chain 5 | 0.0144258 |
| VAV2 | vav 2 guanine nucleotide exchange factor | 0.0144006 |
| CDH12 | cadherin 12, type 2 (N-cadherin 2) | 0.0143251 |
| KIF1A | kinesin family member 1A | 0.0142478 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0141284 |
| CDCA8 | cell division cycle associated 8 | 0.0140823 |
| RPL26 | ribosomal protein L26 | 0.0140646 |
| ARHGAP11A | Rho GTPase activating protein 11A | 0.0140099 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0139913 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.0139793 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0138947 |
| HDGF | hepatoma-derived growth factor | 0.0138884 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.0138654 |
| LMNA | lamin A/C | 0.0137892 |
| GAS2L3 | growth arrest-specific 2 like 3 | 0.0137759 |
| XPO1 | exportin 1 | 0.0137713 |
| GSTP1 | glutathione S-transferase pi 1 | 0.013756 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0137339 |
| STMN1 | stathmin 1 | 0.013667 |
| TMSB10 | thymosin beta 10 | 0.013634 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0136333 |
| CKAP2L | cytoskeleton associated protein 2-like | 0.0135918 |
| INTS1 | integrator complex subunit 1 | 0.0134953 |
| SESN3 | sestrin 3 | 0.0134255 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0133661 |
| NUF2 | NUF2, NDC80 kinetochore complex component | 0.0133207 |
| RNF145 | ring finger protein 145 | 0.0133155 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 0.0133056 |
| TPX2 | TPX2, microtubule-associated | 0.0132876 |
| KIF23 | kinesin family member 23 | 0.0131414 |
| RPLP2 | ribosomal protein, large, P2 | 0.013111 |
| RPL19 | ribosomal protein L19 | 0.0130595 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0129761 |
| RPS25 | ribosomal protein S25 | 0.01294 |
| KNL1 | kinetochore scaffold 1 | 0.0129344 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0128624 |
| H1-0 | H1.0 linker histone | 0.0126783 |
| KIF2C | kinesin family member 2C | 0.0126289 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0125769 |
| ZC3H7A | zinc finger CCCH-type containing 7A | 0.0125714 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NALF1 | NALCN channel auxiliary factor 1 | -0.212368 |
| GPC6 | glypican 6 | -0.172453 |
| NRG1 | neuregulin 1 | -0.15539 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.149161 |
| STC1 | stanniocalcin 1 | -0.127797 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.126359 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.118012 |
| SMYD3 | SET and MYND domain containing 3 | -0.110138 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.106565 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.10204 |
| NDRG1 | N-myc downstream regulated 1 | -0.100109 |
| RORA | RAR-related orphan receptor A | -0.0989497 |
| MAP1B | microtubule-associated protein 1B | -0.0881089 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.0871371 |
| MCL1 | myeloid cell leukemia 1 | -0.0855872 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0834555 |
| KCNB2 | potassium channel, voltage gated Shab related subfamily B, member 2 | -0.0813757 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0807793 |
| SNTG1 | syntrophin, gamma 1 | -0.0773459 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0755476 |
| NBEA | neurobeachin | -0.0710897 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0709119 |
| SCG2 | secretogranin II | -0.070888 |
| ESRRG | estrogen-related receptor gamma | -0.0652024 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | -0.0639523 |
| DTNA | dystrobrevin, alpha | -0.0634299 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0631055 |
| CHGB | chromogranin B | -0.0628114 |
| NKAIN2 | Na+/K+ transporting ATPase interacting 2 | -0.0623088 |
| ACTG1 | actin gamma 1 | -0.0612606 |
| PTCHD4 | patched domain containing 4 | -0.0598544 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0589687 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0585474 |
| EFNA5 | ephrin-A5 | -0.0582433 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0553714 |
| ASPH | aspartate beta-hydroxylase | -0.0540458 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0540369 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0523515 |
| FAM13A | family with sequence similarity 13, member A | -0.0518382 |
| ENO1 | enolase 1, (alpha) | -0.0510737 |
| ST18 | suppression of tumorigenicity 18, zinc finger | -0.0510458 |
| GPC5 | glypican 5 | -0.0490764 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0489867 |
| TMSB4X | thymosin beta 4, X-linked | -0.0486449 |
| EPHA6 | EPH receptor A6 | -0.0479252 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.047321 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0465242 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit | -0.0462857 |
| ARFGEF3 | ARFGEF family member 3 | -0.0462437 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | -0.0459658 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0455708 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0448984 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0422071 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0418438 |
| KIF26B | kinesin family member 26B | -0.0412258 |
| NCKAP5 | NCK-associated protein 5 | -0.0406412 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 | -0.0405482 |
| SETX | senataxin | -0.0402741 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.0401218 |
| EGR1 | early growth response 1 | -0.0400022 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0392139 |
| DENND4A | DENN/MADD domain containing 4A | -0.038285 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0380008 |
| NELL1 | NEL-like 1 (chicken) | -0.0374116 |
| CPE | carboxypeptidase E | -0.0372479 |
| CDK13 | cyclin-dependent kinase 13 | -0.0361291 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | -0.0360933 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0359158 |
| MT2A | metallothionein 2A | -0.0355963 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0352651 |
| KLHL29 | kelch-like family member 29 | -0.035173 |
| CANX | calnexin | -0.0351162 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0348352 |
| TOX | thymocyte selection-associated high mobility group box | -0.0348104 |
| GOLGB1 | golgin B1 | -0.0339095 |
| KCND2 | potassium channel, voltage gated Shal related subfamily D, member 2 | -0.0336 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0334547 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.0332254 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0330621 |
| ZMAT4 | zinc finger, matrin-type 4 | -0.0330286 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0328246 |
| NAV2 | neuron navigator 2 | -0.0325754 |
| ZFHX3 | zinc finger homeobox 3 | -0.0325308 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0324683 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0321353 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0320973 |
| INHBA | inhibin, beta A | -0.0317762 |
| LRFN2 | leucine rich repeat and fibronectin type III domain containing 2 | -0.0317242 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.031445 |
| LSAMP | limbic system-associated membrane protein | -0.0311764 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0307867 |
| ASIC2 | acid sensing (proton gated) ion channel 2 | -0.0304811 |
| TPD52 | tumor protein D52 | -0.0302098 |
| RIT2 | Ras-like without CAAX 2 | -0.0292407 |
| AUTS2 | autism susceptibility candidate 2 | -0.0291706 |
| CNTNAP2 | contactin associated protein-like 2 | -0.0291432 |
| FN1 | fibronectin 1 | -0.0284886 |
| TUSC3 | tumor suppressor candidate 3 | -0.0284317 |
| ZNF804A | zinc finger protein 804A | -0.0280076 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0279502 |
