| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bisoprolol (hemifumarate) perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bisoprolol (hemifumarate)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AHNAK | AHNAK nucleoprotein | 0.188028 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.164256 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.094084 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0861115 |
| VCL | vinculin | 0.0816403 |
| FLNB | filamin B, beta | 0.0770072 |
| PKM | pyruvate kinase, muscle | 0.0726252 |
| EGFR | epidermal growth factor receptor | 0.0681989 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0676604 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0647891 |
| LOC112694756 | uncharaterized LOC112694756 | 0.064528 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0623776 |
| BMP10 | bone morphogenetic protein 10 | 0.0623213 |
| UBC | ubiquitin C | 0.0531387 |
| EZR | ezrin | 0.0530905 |
| GLI2 | GLI family zinc finger 2 | 0.0469322 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0456274 |
| CCND1 | cyclin D1 | 0.0439284 |
| PYGB | phosphorylase, glycogen; brain | 0.0431227 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0429828 |
| ENO1 | enolase 1, (alpha) | 0.0420706 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.038006 |
| RPL4 | ribosomal protein L4 | 0.0365659 |
| APP | amyloid beta (A4) precursor protein | 0.0361014 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0353561 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0353267 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.035135 |
| DUSP4 | dual specificity phosphatase 4 | 0.0344896 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0339163 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0332803 |
| AMOTL2 | angiomotin like 2 | 0.0328605 |
| HDAC9 | histone deacetylase 9 | 0.0320914 |
| GLI3 | GLI family zinc finger 3 | 0.0319541 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0311205 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0307083 |
| MYO5C | myosin VC | 0.0296764 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0293702 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0293106 |
| GSE1 | Gse1 coiled-coil protein | 0.0289446 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0282482 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0272916 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0266571 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.026389 |
| ZNF608 | zinc finger protein 608 | 0.0262071 |
| TXNRD1 | thioredoxin reductase 1 | 0.0258201 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0251997 |
| RPS27A | ribosomal protein S27a | 0.0250238 |
| MYOF | myoferlin | 0.0236336 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | 0.0234079 |
| HDLBP | high density lipoprotein binding protein | 0.0232187 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0232114 |
| PLXNA1 | plexin A1 | 0.0230619 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0227031 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0224053 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0220903 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0220751 |
| ANLN | anillin, actin binding protein | 0.0219524 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | 0.0216476 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0216196 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0215258 |
| FOXP1 | forkhead box P1 | 0.0213111 |
| ATP9B | ATPase, class II, type 9B | 0.0212231 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0204108 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0202402 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0202038 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0199517 |
| FBLN2 | fibulin 2 | 0.0193168 |
| CRPPA | CDP-L-ribitol pyrophosphorylase A | 0.0191124 |
| FAT1 | FAT atypical cadherin 1 | 0.018843 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0187407 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.0184358 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0182899 |
| SQSTM1 | sequestosome 1 | 0.0182539 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0179275 |
| TBL1X | transducin (beta)-like 1X-linked | 0.0177856 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0177345 |
| UNC13A | unc-13 homolog A (C. elegans) | 0.0177153 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.0173776 |
| MARS1 | methionyl-tRNA synthetase 1 | 0.0173213 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0172345 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0171252 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0171055 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.0169342 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.016896 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | 0.0168132 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.016736 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0165851 |
| RPL37A | ribosomal protein L37a | 0.0165422 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.0161315 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0161167 |
| ZNF217 | zinc finger protein 217 | 0.016062 |
| FHAD1 | forkhead-associated (FHA) phosphopeptide binding domain 1 | 0.0160061 |
| ACTN4 | actinin, alpha 4 | 0.0158391 |
| SEPTIN9 | septin 9 | 0.0158281 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.0157416 |
| IRS1 | insulin receptor substrate 1 | 0.0155837 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.0155119 |
| LOXL3 | lysyl oxidase-like 3 | 0.0154459 |
| VAPB | VAMP (vesicle-associated membrane protein)-associated protein B and C | 0.0153862 |
| ZNF106 | zinc finger protein 106 | 0.0153525 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.116255 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.101765 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0691223 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0634353 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0594418 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0590892 |
| PFN1 | profilin 1 | -0.055762 |
| ZNF292 | zinc finger protein 292 | -0.0527578 |
| GOLGA4 | golgin A4 | -0.0522727 |
| PTMA | prothymosin, alpha | -0.0504131 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0499656 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0488161 |
| RPL35A | ribosomal protein L35a | -0.0472696 |
| RBM39 | RNA binding motif protein 39 | -0.0451703 |
| SETD5 | SET domain containing 5 | -0.0420478 |
| EVI5 | ecotropic viral integration site 5 | -0.0418147 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0395943 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0394264 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0389147 |
| QKI | QKI, KH domain containing, RNA binding | -0.0389083 |
| NUP58 | nucleoporin 58 | -0.0387007 |
| RPLP0 | ribosomal protein, large, P0 | -0.038609 |
| CCNL1 | cyclin L1 | -0.0383582 |
| TXNIP | thioredoxin interacting protein | -0.038347 |
| RPS19 | ribosomal protein S19 | -0.0382412 |
| XPO1 | exportin 1 | -0.0379472 |
| DSTN | destrin (actin depolymerizing factor) | -0.0371404 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.036739 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0364486 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0357424 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0357026 |
| ACTG1 | actin gamma 1 | -0.035634 |
| FAM162A | family with sequence similarity 162, member A | -0.0356256 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0353084 |
| RNF145 | ring finger protein 145 | -0.0341961 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0331263 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0325347 |
| FTL | ferritin, light polypeptide | -0.0322049 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.032153 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0319687 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0311745 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0310477 |
| PCM1 | pericentriolar material 1 | -0.0309906 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0308038 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0305859 |
| PHIP | pleckstrin homology domain interacting protein | -0.0300889 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0297584 |
| RPL27A | ribosomal protein L27a | -0.0294567 |
| SEPTIN7 | septin 7 | -0.0289608 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0289195 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0287445 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0285158 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0284402 |
| ECT2 | epithelial cell transforming 2 | -0.0276471 |
| POTEF | POTE ankyrin domain family, member F | -0.0274882 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0273053 |
| CDC73 | cell division cycle 73 | -0.0266768 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.026092 |
| TFG | TRK-fused gene | -0.0260723 |
| COPA | coatomer protein complex, subunit alpha | -0.0259011 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0258905 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0256615 |
| HELZ | helicase with zinc finger | -0.0252643 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0251457 |
| SRP54 | signal recognition particle 54kDa | -0.0248683 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0247459 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0246999 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.024369 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.0243557 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0243367 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0242477 |
| RPS23 | ribosomal protein S23 | -0.0237876 |
| USP3 | ubiquitin specific peptidase 3 | -0.0236127 |
| DENND4C | DENN/MADD domain containing 4C | -0.0235958 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0234293 |
| SRPK2 | SRSF protein kinase 2 | -0.023282 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0232088 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0231969 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0231394 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0228817 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0228684 |
| KIF5B | kinesin family member 5B | -0.0228638 |
| GNAS | GNAS complex locus | -0.0228498 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.022737 |
| SKIC3 | SKI3 subunit of superkiller complex | -0.0226714 |
| MTF2 | metal response element binding transcription factor 2 | -0.0224251 |
| ARF4 | ADP-ribosylation factor 4 | -0.0223305 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | -0.0221774 |
| ATOSA | atos homolog A | -0.0219998 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0215687 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0215651 |
| ZNF207 | zinc finger protein 207 | -0.0215234 |
| RLF | rearranged L-myc fusion | -0.0214224 |
| RPL21 | ribosomal protein L21 | -0.0214151 |
| RPS24 | ribosomal protein S24 | -0.0212201 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.0212193 |
| NF1 | neurofibromin 1 | -0.0211933 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0210833 |
| CALR | calreticulin | -0.0210346 |
| JMJD1C | jumonji domain containing 1C | -0.0209536 |
