| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bisoprolol (hemifumarate) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bisoprolol (hemifumarate)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.141581 |
| FN1 | fibronectin 1 | 0.105006 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0687336 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0636402 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0632128 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0595072 |
| RTN4 | reticulon 4 | 0.0531069 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0506083 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0482712 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0449718 |
| MKI67 | marker of proliferation Ki-67 | 0.041292 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0412155 |
| MSN | moesin | 0.0407726 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0333758 |
| TPM4 | tropomyosin 4 | 0.0318381 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0303871 |
| CENPF | centromere protein F, 350/400kDa | 0.0302308 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.027961 |
| ARRDC3 | arrestin domain containing 3 | 0.0278833 |
| ATP13A3 | ATPase type 13A3 | 0.0266941 |
| ZNF292 | zinc finger protein 292 | 0.0265928 |
| ANLN | anillin, actin binding protein | 0.0257004 |
| DENND5A | DENN/MADD domain containing 5A | 0.0241895 |
| KIF4A | kinesin family member 4A | 0.0231941 |
| THBS1 | thrombospondin 1 | 0.0229153 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0220006 |
| DUSP5 | dual specificity phosphatase 5 | 0.02132 |
| TXNRD1 | thioredoxin reductase 1 | 0.0210071 |
| TPX2 | TPX2, microtubule-associated | 0.0209194 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0205829 |
| DIAPH3 | diaphanous-related formin 3 | 0.0202377 |
| SDC4 | syndecan 4 | 0.0201772 |
| CDCP1 | CUB domain containing protein 1 | 0.020091 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0198695 |
| TAPBP | TAP binding protein (tapasin) | 0.0196281 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0191495 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0188862 |
| KLF6 | Kruppel-like factor 6 | 0.0187386 |
| TMEM123 | transmembrane protein 123 | 0.0186527 |
| SYAP1 | synapse associated protein 1 | 0.0182065 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0180582 |
| SMAD3 | SMAD family member 3 | 0.017712 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0173339 |
| CLIC4 | chloride intracellular channel 4 | 0.0173297 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0172133 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0169934 |
| NUP153 | nucleoporin 153kDa | 0.0166267 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.016426 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0162712 |
| KIF11 | kinesin family member 11 | 0.0162632 |
| FLNA | filamin A, alpha | 0.0159197 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0155339 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0154305 |
| ACTN1 | actinin, alpha 1 | 0.0152575 |
| TRAF3IP2 | TRAF3 interacting protein 2 | 0.0152262 |
| RUNX2 | runt-related transcription factor 2 | 0.0150656 |
| MX1 | MX dynamin-like GTPase 1 | 0.0150619 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0150552 |
| LDLR | low density lipoprotein receptor | 0.0150433 |
| YME1L1 | YME1-like 1 ATPase | 0.0148693 |
| TMEM41B | transmembrane protein 41B | 0.0145366 |
| OSMR | oncostatin M receptor | 0.0144572 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0143939 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0142564 |
| TUBB | tubulin, beta class I | 0.0141957 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0141828 |
| PLPP3 | phospholipid phosphatase 3 | 0.0136149 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0135295 |
| ANXA5 | annexin A5 | 0.0134709 |
| CALD1 | caldesmon 1 | 0.0134429 |
| TXNIP | thioredoxin interacting protein | 0.0133762 |
| TTK | TTK protein kinase | 0.0133759 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0133664 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0133081 |
| CDC42SE2 | CDC42 small effector 2 | 0.0132939 |
| IL6ST | interleukin 6 signal transducer | 0.0132641 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0132035 |
| RASA2 | RAS p21 protein activator 2 | 0.0132023 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0131877 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0130957 |
| EZR | ezrin | 0.0128515 |
| ADNP | activity-dependent neuroprotector homeobox | 0.0127347 |
| PRKCSH | protein kinase C substrate 80K-H | 0.0126641 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0126558 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0126496 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0125851 |
| NAV2 | neuron navigator 2 | 0.0125298 |
| TGFB2 | transforming growth factor, beta 2 | 0.0123866 |
| ECT2 | epithelial cell transforming 2 | 0.0123813 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0123516 |
| AXL | AXL receptor tyrosine kinase | 0.0123429 |
| MED14 | mediator complex subunit 14 | 0.0119498 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0119343 |
| KIF18A | kinesin family member 18A | 0.0118528 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0118391 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0118212 |
| APP | amyloid beta (A4) precursor protein | 0.0117016 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0115581 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0115401 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.01147 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.175848 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.138024 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.111266 |
| FRMD4A | FERM domain containing 4A | -0.108033 |
| HLA-B | major histocompatibility complex, class I, B | -0.0967428 |
| FTL | ferritin, light polypeptide | -0.0966353 |
| HMGA2 | high mobility group AT-hook 2 | -0.092926 |
| TMSB10 | thymosin beta 10 | -0.0918295 |
| GLIS3 | GLIS family zinc finger 3 | -0.0908411 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0770474 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0701606 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.068577 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0673915 |
| CDH13 | cadherin 13 | -0.0671825 |
| HDAC9 | histone deacetylase 9 | -0.0660685 |
| RPS6 | ribosomal protein S6 | -0.0657237 |
| MT2A | metallothionein 2A | -0.0650917 |
| DST | dystonin | -0.0637185 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0615936 |
| RPL23 | ribosomal protein L23 | -0.0595548 |
| B2M | beta-2-microglobulin | -0.0587027 |
| INTS6 | integrator complex subunit 6 | -0.0577756 |
| RPL37A | ribosomal protein L37a | -0.0571958 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0562787 |
| RPS8 | ribosomal protein S8 | -0.0558098 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0554662 |
| RPS3 | ribosomal protein S3 | -0.0540361 |
| RPS12 | ribosomal protein S12 | -0.0538207 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0509214 |
| HLA-A | major histocompatibility complex, class I, A | -0.0503969 |
| RPL9 | ribosomal protein L9 | -0.0502436 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0478699 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0475067 |
| LDHA | lactate dehydrogenase A | -0.0471782 |
| PDE10A | phosphodiesterase 10A | -0.0471542 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0460083 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0453415 |
| RAI14 | retinoic acid induced 14 | -0.0450027 |
| RPLP1 | ribosomal protein, large, P1 | -0.0441383 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0441144 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0439812 |
| IER3 | immediate early response 3 | -0.0436153 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0433474 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0432391 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0418078 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0417193 |
| SQSTM1 | sequestosome 1 | -0.0410623 |
| RPS19 | ribosomal protein S19 | -0.0407468 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0399524 |
| RPL26 | ribosomal protein L26 | -0.0397341 |
| RACK1 | receptor for activated C kinase 1 | -0.0390303 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0381773 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.037768 |
| DIAPH2 | diaphanous-related formin 2 | -0.037237 |
| RPL5 | ribosomal protein L5 | -0.0363695 |
| NDRG1 | N-myc downstream regulated 1 | -0.036161 |
| RPL31 | ribosomal protein L31 | -0.0343722 |
| RPL12 | ribosomal protein L12 | -0.0343456 |
| EFNA5 | ephrin-A5 | -0.034208 |
| RPL19 | ribosomal protein L19 | -0.0329798 |
| CANX | calnexin | -0.0328643 |
| PTMA | prothymosin, alpha | -0.0325305 |
| RPL35A | ribosomal protein L35a | -0.0324176 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0321396 |
| RPL36 | ribosomal protein L36 | -0.0320407 |
| ATXN1 | ataxin 1 | -0.0315975 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0315669 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0313076 |
| ASPH | aspartate beta-hydroxylase | -0.0312328 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.030968 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0299708 |
| COL5A1 | collagen, type V, alpha 1 | -0.0298579 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0298482 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0297424 |
| RND3 | Rho family GTPase 3 | -0.0294548 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0292023 |
| RPL11 | ribosomal protein L11 | -0.0291562 |
| EGFR | epidermal growth factor receptor | -0.0290554 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0290331 |
| ADM | adrenomedullin | -0.0289328 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.028899 |
| PRELID2 | PRELI domain containing 2 | -0.0286966 |
| RPS4X | ribosomal protein S4, X-linked | -0.0286302 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0285797 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0284188 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0284077 |
| RPS14 | ribosomal protein S14 | -0.0282658 |
| ACTG1 | actin gamma 1 | -0.028144 |
| GOLGB1 | golgin B1 | -0.027742 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0275442 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0272073 |
| PLIN2 | perilipin 2 | -0.0271656 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0270973 |
| PRKCA | protein kinase C, alpha | -0.0270947 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0268952 |
| PHF3 | PHD finger protein 3 | -0.0268324 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0262242 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0260992 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0256576 |
| RPL13A | ribosomal protein L13a | -0.0256284 |
