| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bisoprolol (hemifumarate) perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bisoprolol (hemifumarate)_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FGFR2 | fibroblast growth factor receptor 2 | 0.0510779 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0330357 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0329009 |
| FLNA | filamin A, alpha | 0.0311324 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0306267 |
| PDE10A | phosphodiesterase 10A | 0.0304674 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.028476 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0277679 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0256057 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0253022 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0243539 |
| EP400 | E1A binding protein p400 | 0.0240948 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | 0.0239229 |
| NPSR1 | neuropeptide S receptor 1 | 0.0237394 |
| SDC4 | syndecan 4 | 0.0236247 |
| RPS16 | ribosomal protein S16 | 0.0235599 |
| CD2AP | CD2-associated protein | 0.023212 |
| FRMD6 | FERM domain containing 6 | 0.0229471 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0229356 |
| ACTN4 | actinin, alpha 4 | 0.0224931 |
| H1-0 | H1.0 linker histone | 0.0223565 |
| CORO1C | coronin, actin binding protein, 1C | 0.0222249 |
| MSI2 | musashi RNA-binding protein 2 | 0.0220851 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.021901 |
| ZFP36 | ZFP36 ring finger protein | 0.0217751 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0211234 |
| MNT | MAX network transcriptional repressor | 0.0209597 |
| RASA2 | RAS p21 protein activator 2 | 0.0203885 |
| AHNAK | AHNAK nucleoprotein | 0.0202493 |
| ZNF292 | zinc finger protein 292 | 0.0200021 |
| POM121 | POM121 transmembrane nucleoporin | 0.0199201 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0198784 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0198208 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0196993 |
| RORA | RAR-related orphan receptor A | 0.0195776 |
| RPS2 | ribosomal protein S2 | 0.0195246 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0195237 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0194974 |
| KLF6 | Kruppel-like factor 6 | 0.0193783 |
| RPL4 | ribosomal protein L4 | 0.0193552 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0192785 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0192232 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0191941 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0191842 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0189593 |
| SPAG9 | sperm associated antigen 9 | 0.0189088 |
| MORF4L2 | mortality factor 4 like 2 | 0.018867 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0187597 |
| MT1X | metallothionein 1X | 0.0186886 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | 0.018658 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0183937 |
| KRT18 | keratin 18, type I | 0.0183266 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0182327 |
| PELP1 | proline, glutamate and leucine rich protein 1 | 0.0180979 |
| TMEM259 | transmembrane protein 259 | 0.0179829 |
| FLNB | filamin B, beta | 0.0178398 |
| FOCAD | focadhesin | 0.0177992 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0177677 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0177312 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0176753 |
| CARS1 | cysteinyl-tRNA synthetase 1 | 0.0176648 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0176567 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0175594 |
| IQSEC1 | IQ motif and Sec7 domain 1 | 0.0175211 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0174989 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0172464 |
| VGF | VGF nerve growth factor inducible | 0.0172115 |
| SEC14L2 | SEC14-like 2 (S. cerevisiae) | 0.0172088 |
| ANKMY2 | ankyrin repeat and MYND domain containing 2 | 0.0171735 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0171254 |
| APP | amyloid beta (A4) precursor protein | 0.0170892 |
| HMGA1 | high mobility group AT-hook 1 | 0.0169422 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0169069 |
| FHIT | fragile histidine triad | 0.0169053 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0169003 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0168028 |
| DIPK1A | divergent protein kinase domain 1A | 0.0167469 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0167235 |
| SAFB2 | scaffold attachment factor B2 | 0.0167098 |
| CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | 0.0166391 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 0.0166358 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0166204 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0166108 |
| CLSTN1 | calsyntenin 1 | 0.0165951 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0165859 |
| MINK1 | misshapen-like kinase 1 | 0.0165614 |
| DYNC1I2 | dynein, cytoplasmic 1, intermediate chain 2 | 0.0165576 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0164646 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.0163437 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0162971 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0162866 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0162739 |
| UBE3A | ubiquitin protein ligase E3A | 0.0162469 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0162431 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0161999 |
| SYT1 | synaptotagmin I | 0.0161273 |
| RPL13A | ribosomal protein L13a | 0.0161091 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0160709 |
| CMC2 | C-x(9)-C motif containing 2 | 0.015945 |
| YBX3 | Y box binding protein 3 | 0.0158895 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.380981 |
| VIM | vimentin | -0.197069 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.18418 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.151156 |
| FN1 | fibronectin 1 | -0.150799 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.150478 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.132784 |
| HLA-B | major histocompatibility complex, class I, B | -0.129186 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.12776 |
| B2M | beta-2-microglobulin | -0.12467 |
| POTEF | POTE ankyrin domain family, member F | -0.0949218 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0926665 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0864189 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0862408 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0856834 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0766845 |
| COL6A1 | collagen, type VI, alpha 1 | -0.075506 |
| CD44 | CD44 molecule (Indian blood group) | -0.0698102 |
| MAP1B | microtubule-associated protein 1B | -0.0677244 |
| ENO1 | enolase 1, (alpha) | -0.0633515 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0613143 |
| CDH13 | cadherin 13 | -0.0612959 |
| IL6 | interleukin 6 | -0.0584156 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0581505 |
| CALD1 | caldesmon 1 | -0.0580051 |
| MT2A | metallothionein 2A | -0.052803 |
| SEPTIN7 | septin 7 | -0.0515528 |
| CALR | calreticulin | -0.0507155 |
| CANX | calnexin | -0.0503356 |
| CALU | calumenin | -0.0494752 |
| UBC | ubiquitin C | -0.0493481 |
| STC1 | stanniocalcin 1 | -0.049016 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0486677 |
| NAV1 | neuron navigator 1 | -0.0468114 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0463505 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0459466 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0451438 |
| GLIS3 | GLIS family zinc finger 3 | -0.0441545 |
| LOX | lysyl oxidase | -0.0432551 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0429995 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0425387 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0424793 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0420047 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0416611 |
| S100A10 | S100 calcium binding protein A10 | -0.041323 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0405899 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0404403 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0394923 |
| ASPH | aspartate beta-hydroxylase | -0.0389899 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0370686 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0361426 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0358413 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0346813 |
| VEGFC | vascular endothelial growth factor C | -0.0343567 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | -0.0337309 |
| ZNF395 | zinc finger protein 395 | -0.0334626 |
| VEGFA | vascular endothelial growth factor A | -0.0329507 |
| FTL | ferritin, light polypeptide | -0.0327625 |
| TMSB10 | thymosin beta 10 | -0.0327328 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0323766 |
| TPM4 | tropomyosin 4 | -0.0321834 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.03182 |
| ACTG1 | actin gamma 1 | -0.0317781 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.03139 |
| PGK1 | phosphoglycerate kinase 1 | -0.0309711 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0308507 |
| RNF24 | ring finger protein 24 | -0.0306043 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0300517 |
| NRXN3 | neurexin 3 | -0.0299178 |
| COG6 | component of oligomeric golgi complex 6 | -0.0298185 |
| PKM | pyruvate kinase, muscle | -0.0296589 |
| TNS3 | tensin 3 | -0.0294623 |
| HLA-A | major histocompatibility complex, class I, A | -0.0294587 |
| CDK6 | cyclin-dependent kinase 6 | -0.0293615 |
| TMSB4X | thymosin beta 4, X-linked | -0.0289156 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.0288328 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.028273 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0282099 |
| RAI14 | retinoic acid induced 14 | -0.0274902 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0265158 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0263425 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0260952 |
| FNDC3A | fibronectin type III domain containing 3A | -0.026027 |
| ANXA5 | annexin A5 | -0.0257933 |
| RTN4 | reticulon 4 | -0.025556 |
| HMGA2 | high mobility group AT-hook 2 | -0.0254112 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0253363 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0251466 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0250465 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0249957 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0249049 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0242653 |
| KYNU | kynureninase | -0.0241203 |
| ARF4 | ADP-ribosylation factor 4 | -0.0240729 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0239651 |
| COL1A2 | collagen, type I, alpha 2 | -0.02384 |
| HLA-C | major histocompatibility complex, class I, C | -0.0237908 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0237578 |
| RPS6 | ribosomal protein S6 | -0.0237027 |
| HIP1 | huntingtin interacting protein 1 | -0.0233892 |
